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Malattie dellapparato respiratorio = Respiratory system diseases

This book reports the status of the art of the community more diseases of the respiratory apparatus. The first part is dedicated to the anatomy of the lung, to the regulation of the respiration and to the respiratory mechanics, follows the functionalities of the respiratory pain and the invasive and non-invasive diagnosis, including the diagnosis per imaging in pneumology. Nella description of the particular malattie importance of this date in the chiarire the "perché" of the diversi symptoms and according to the clinical practice within the therapeutic approach, confronted with te international guideline, with the communication of the vast experience of the clinic of the author. The main objective of this book is that the recent acquisition of the physiology, pathophysiology and clinic of the respiratory system, including non-invasive mechanical ventilation, oxygen therapy and respiratory rehabilitation, and combining a clear description from the respiratory pathophysiology with emphasis on its clinical application. The volume is aimed both at students of the specialist degree course in medicine and surgery, and at specialists in diseases of the respiratory system. It also represents a valid reference for the general medicine doctor, above all when the last intention will increase the proprietary knowledge of clinics, diagnosis and therapy in the sector of the respiratory pathology, branch that always is often shared by the doctor and the specialist in the risoluzione of almost anche molto complessi.

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Lysosomal Storage Disorders

This book is dedicated to patients affected by Lysosomal Storage Disorders, and especially to the National Gaucher Foundation (USA) and the Colombian Association of Patients with Lysosomal Storage Diseases (ACOPEL for its Spanish Acronym). Both organizations will share in the sales of this book.

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Lung Pathology

Learning the diagnostic elements of lung pathology requires not only great familiarity with a wide diversity of cases, but also a sharp eye for analyzing pictorial images. In Lung Pathology: A Consultative Atlas, leading experts offer a novel and substantive approach to the teaching of pulmonary pathology. Drawing on 263 challenging, yet exemplary, referral cases taken from files collected over 20 years by internationally renowned lung pathologist, Dr. Eugene Mark, the authors introduce his state-of-the-art approach to the interpretation of pulmonary pathology. This text includes the primary and/or differential diagnosis and the pertinent histological features of each case, as well as clinical history, when available. Key words or phrases in the text are highlighted and digitally hyperlinked to associated images or regions of interest within those images to assist the readers in their correlation. Novel and user friendly, Lung Pathology: A Consultative Atlas describes a cutting-edge diagnostic approach to pulmonary pathology, describing its principles and demonstrating its application in text and full-color illustrations drawn from 263 difficult cases of human lung pathologies.

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Lectins

In the intervening years well over 10,000 articles have appeared with lectins as the main subject, and more than twice as many in which they were touched upon, as well as around 20 books. In particular, great strides have been made in several areas of lectin research, about which little was known until the late 1980s. One prominent example is animal lectins, many of which have been discovered only during the last decade and the functions of several of which have been clarified, especially as to their key role in innate immunity.

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Le complicazioni neurologiche in oncologia = Neurological complications in oncology

This volume, both necessary and new in the panorama of Italian medical literature, acknowledges this and presents an updated and complete review of the pathologies of the central and peripheral nervous system associated with tumors and their treatment. The purpose of the volume is to present an integrated approach between specialists that must see the neurologist and the oncologist in dialogue, and able to develop a new super-specialized clinical capacity in neuro-oncology. Many experts have contributed to its preparation by sharing knowledge on topics ranging from metastatic complications, to those of surgical cancer therapy, radio- and chemo-therapy, paraneoplastic syndromes, pain therapy, delirium and the affective alterations associated with the disease. The book is aimed in particular at neurologists, oncologists, palliative care practitioners and surgeons, but it is certainly useful for general practitioners and all operators who are daily involved in the demanding work of taking care of cancer patients.

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Computational biology in drug discovery and repurposing

Takes an in-depth look at the emerging and prospective field of computational biology and bioinformatics, which possesses the ability to analyze large accumulated biological data collected from sequence analysis of proteins and genes and cell population with an aim to make new predictions pertaining to drug discovery and new biology. The book explains the basic methodology associated with a bioinformatics and computational approach in drug designing. It then goes on to cover the implementation of computational programming, bioinformatics, pharmacophore modeling, biotechnological techniques, and pharmaceutical chemistry in designing drugs. The major advantage of intervention of computer language or programming is to cut down the number of steps and costs in the field of drug designing, reducing the repeating steps and saving time in screening the potent component for drug or vaccine designin

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Cleaning validation : Practical compliance approaches for pharmaceutical manufacturing

Timely coverage of cleaning validation for the pharmaceutical industry, a dynamic area in terms of health-based limits. Encourages pharmaceutical manufacturers, and particularly upper management, to meet the challenges of the science-based and riskbased approaches to cleaning validation. Draws on the author’s vast experience in the field of cleaning validation and hazardous materials. Discusses EMA vs. ISPE on Cleaning Limits and revised Risk-MaPP for highly hazardous products in shared facilities. A diverse list of topics from protocol limits for yeasts and molds to cleaning validation for homeopathic drug products.

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Chemoinformatics and Bioinformatics in the Pharmaceutical Sciences

Chemoinformatics and Bioinformatics in the Pharmaceutical Sciences brings together two very important fields in pharmaceutical sciences that have been mostly seen as diverging from each other: chemoinformatics and bioinformatics. As developing drugs is an expensive and lengthy process, technology can improve the cost, efficiency and speed at which new drugs can be discovered and tested. This book presents some of the growing advancements of technology in the field of drug development and how the computational approaches explained here can reduce the financial and experimental burden of the drug discovery process.

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Cancer Informatics in the Post Genomic Era : Toward Information-Based Medicine

Medical information science requires analytic tools. This is achieved by developing and assessing methods and systems for the acquisition, processing, and interpretation of patient data, aided by scientific discovery. Cancer Informatics in Post-Genomic Era provides both the necessary methodology and practical information tools.Key challenges include integrating research and clinical care, sharing data, and establishing partnerships within and across sectors of patient diagnosis and treatment.Addressing important clinical questions in cancer research will benefit from expanding computational biology.

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Breast MRI : Diagnosis and Intervention

This superbly illustrated practical guide is an excellent resource on all aspects of breast MRI for practicing radiologists, oncologists, and surgeons, as well as residents and fellows. Drs. Elizabeth Morris and Laura Liberman, two experts in the field from the Memorial Sloan-Kettering Cancer Center, have collaborated with colleagues from their institution and selected medical centers to share their expertise. Introductory chapters are devoted to diagnosis and cover the basics of performing breast MRI exams, setting up a breast MRI program, and understanding clinical indications. Additional chapters discuss breast interventional procedures including MRI-guided needle localization, MRI-guided biopsy, and percutaneous ablation of breast cancer; MRI of breast implants.

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Biotechnology of medicinal plants with antiallergy properties : Research trends and prospects

Covers critically investigated information on medicinal plants prioritized for their anti-allergy properties. It offers insights into strategies related to the distribution, mechanism of action, and assessment of antiallergic medicinal plants, and also delves into crucial aspects of modern biotechnological tools, addressing their implementation challenges, presenting innovative approaches through case studies, and exploring opportunities for nanotechnologies. These elaborated discussions aim to raise awareness and bridge the gap between human health and the biodiversity of antiallergic medicinal plants.

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Bioinformatics drug discovery

Quantitative tools are becoming increasingly important in order to understand complex cascade of signal transduction events, pathways or biochemical reactions. The book showcases how computational techniques and algorithms are applied to biological data analysis, interpretation, and modelling. It covers applications in drug design and discovery, immune systems, phylogenetic analysis and protein structures.

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Bacterial Physiology : A Molecular Approach

The application of new molecular methodologies in the study of bacterial behaviour and cell architecture has enabled new revolutionary insights and discoveries in these areas. While this has also raised a number of scientific mysteries about bacteria, it certainly improved our understanding of these organisms as complex and adaptive entities rather than just simple tiny buckets of enzymes. The value of this recent knowledge in bacterial physiology is not only restricted to fundamental biology, but it also extends to biotechnology and drug-discovery disciplines where understanding cell behaviour and structure is essential for better exploitation of useful bacteria and effective eradication of harmful ones. This makes a new text accommodating recent developments in bacterial physiology highly relevant to a wide range of readership including those interested in basic and applied knowledge.

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Analytical Techniques in Forensic Science

Analytical Techniques in Forensic Science is a comprehensive guide written in accessible terms that examines the interface between analytical chemistry and trace evidence in forensic science. With contributions from noted experts on the topic, the text features a detailed introduction analysis in forensic science and then subsequent chapters explore the laboratory techniques grouped by shared operating principles. For each technique, the authors incorporate specific theory, application to forensic analytics, interpretation, forensic specific developments, and illustrative case studies.

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Aesthetic Surgery of the Facial Mosaic

This authoritative reference book assembles the experience of an international faculty of authors, each of whom has performed several thousand facelifts, i.e. procedures to rejuvenate and harmonize the human face. All procedures in this regard are covered and the text is accompanied by extensive artwork and photographs. The authors share their experience, including tips and tricks, as well as ways to avoid complications and pitfalls. Special emphasis is given to the concept of looking at the face as a mosaic, i.e. treating its individual parts in a harmonic way and maintaining mimic units. Combining different methods.

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Advances in flavonoids for human health and prevention of diseases

In response to the recent upsurge of interest in the therapeutic potential of medicinal plants, with their promising phenolic compounds, this new book offers an important overview of advances in the applications of flavonoids for health. The book explores the nutritional and pharmacological properties of polyphenols and flavonoids, including their ability to prevent the start and development of diseases and how they aid in the management of several chronic pathological illnesses, including cancer, diabetes, cardiovascular disease, neuro-degenerative illness and aging, pregnancy-induced disorders, and others. Also discussed in depth are the properties, classes, and degrees that formulate a phenolic compound and which subsequently supports the development of drugs/products with health benefits.

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Advances in Breast Cancer Management, 2nd ed.

Advances in Breast Cancer Management, Second Edition will highlight many of the important advances that have transformed our understanding of the biology and therapeutics of breast cancer.

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Adapting dermal fillers in clinical practice

There have been many different brands of dermal fillers approved for use for soft tissue augmentation in the US market alone, comprising four different types of temporary fillers and one permanent type, with several other brands and types also available elsewhere in the world. Against such a potentially bewildering variety and range of choices, this new text offers a scientific and an anatomic rationale for why a particular filler should be selected as optimal for each individual location and indication and how it should best be used in treatments. International experts share their clinical knowledge and expertise to guide all levels of aesthetic practitioners toward the best results for each individual patient.

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Active Processes and Otoacoustic Emissions in Hearing

Sounds that are actually produced by healthy ears allow researchers and clinicians to study hearing and cochlear function noninvasively in both animals and humans. Active Processes and Otoacoustic Emissions in Hearing presents the first serious review of the biological basis of these otoacoustic emissions. Active processes, such as those in hair cells that produce emissions, represent a burgeoning and important area of sensory research. By providing a basis for understanding how and why otoacoustic emissions testing works through a basic understanding of general hearing processes, this volume will also interest clinicians, particularly otolaryngologists and audiologists.

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Blockchain, artificial intelligence, and the internet of things : Possibilities and opportunities

Provides basic concepts and deep knowledge about various security mechanisms that can be implemented in IoT through Blockchain technology. This book aids readers in gaining insight and knowledge about providing security and solutions to different challenges in IoT using Blockchain technology. This book primarily focuses on challenges to addressing the integration of the IoT with Blockchain with respect to potential benefits for IoT. This book gives descriptive analysis of Blockchain integrated with IoT applications and platforms for the development of IoT solutions along with possible topologies to that integration. Several application examples are included in a variety of industries / Provides the latest on secure IIoT communication using Blockchain technology for Industry 4.0 / Includes updates on using Blockchain technology in secure vehicular communication (VANET), healthcare, retail, and gaming / Provides the latest on secure IIoT communication using Blockchain technology for Industry 4.0

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