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Management of Complications in Refractive Surgery

This guide offers the reader practical pearls to the solution and prevention of the different complications of corneal and refractive surgery. All complications are described and lavishly illustrated from its pathogenesis to its treatment modalities.

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Macular Degeneration

Macular Degeneration: Science and Medicine in Practice provides a unique overview of current thinking in the pathogenesis, incidence and treatment of AMD. It includes, for the first time, a synthesis of the views of the world's leading scientists and practitioners regarding retinal biology, basic mechanisms, clinical and pathogenetic processes, and rational approaches to intervention.

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Common Eye Diseases and their Management

There have been significant advances in the diagnosis and management of eye disease since the last edition of Common Eye Diseases and their Management was published. The specialty has developed more subspecialties, and the referring doctor has to have a good knowledge of these in order to make appropriate referrals. An increased emphasis on screening has made it necessary for the primary care doctor to have a basic knowledge of eye diseases. This applies particularly to glaucoma and diabetic eye disease. The management of eye conditions in the elderly is also an important and increasing primary care problem.

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Cell Cycle Regulation

The cell cycle is tightly regulated on many different levels to ensure properly controlled proliferation. Deregulation of cell cycle regulation is a hallmark of cancer. In this book, many aspects of cell cycle regulation are discussed, which include G1, S, M phase control, ubiquitin-mediated degradation, DNA damage response, mitotic spindle checkpoint, the centrosome cycle, Retinoblastoma protein family, the Myc oncogene, and mouse models for tumor suppressors, cyclin-dependent kinases, and meiosis. These chapters written by experts provide an updated view on how the cell cycle is regulated in vivo and about the involvement of cell cycle regulators in cancer.

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Calcium Signalling and Disease : Molecular Pathology of Calcium

This topic is a new entry in the area of cellular calcium signaling: yet, it now spans the entire area, with discoveries that cover both genetic and acquired pathologies, even offering glimpses in the direction of therapy.Cellular calcium homeostasis, and thus calcium signalling, is mainly regulated by membrane intrinsic proteins and calcium sensor proteins. Both classes may be involved in pathological processes that affect both human and animals, ranging from common and important diseases (e.g. migraine, diabetes, epilepsia, manic depression, infertility, various types of cancer, Alzheimer’s disease, muscular dystrophy) to rare genetic conditions (e.g., a number of genetic heart conditions, autoimmune retinopathies, night blindness, hereditary amyloid polyneuropathy, malignant hyperthermia, cerebellar ataxia, atherothrombotic disease).

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Blood traces : Interpretation of deposition and distribution

Blood Traces provides an authoritative resource that reviews many of the aspects of the interpretation of blood traces that have not been treated with the thoroughness they deserve. With strict adherence to the scientific method, the authors — noted experts on the topic — address the complexities encountered when interpreting blood trace configurations. The book provides an understanding of the scientific basis for the use of blood trace deposits, i.e. bloodstain patterns, at crime scenes to better reconstruct a criminal event.

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Acute Promyelocytic Leukemia : Molecular Genetics, Mouse Models and Targeted Therapy

Over the past 10 years, work on acute promyelocytic leukemia (APL) has become the paradigm of translational research that began with the discovery of a recurrent chromosomal translocation, followed by the identification of the genes and proteins involved, finding their molecular functions in transcriptional control, establishing mouse models and culminating in the development of targeted therapy.

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Machine Learning and Probabilistic Graphical Models for Decision Support Systems

Presents recent advancements in research, a review of new methods and techniques, and applications in decision support systems (DSS) with Machine Learning and Probabilistic Graphical Models, which are very effective techniques in gaining knowledge from Big Data and in interpreting decisions. It explores Bayesian network learning, Control Chart, Reinforcement Learning for multicriteria DSS, Anomaly Detection in Smart Manufacturing with Federated Learning, DSS in healthcare, DSS for supply chain management, etc. Researchers and practitioners alike will benefit from this book to enhance the understanding of machine learning, Probabilistic Graphical Models, and their uses in DSS in the context of decision making with uncertainty. The real-world case studies in various fields with guidance and recommendations for the practical applications of these studies are introduced in each chapter.

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Advancement of Deep Learning and its Applications in Object Detection and Recognition

In just the past five years, deep learning has taken the world by surprise, driving rapid progress in fields as diverse as computer vision, natural language processing, automatic speech recognition, etc. This book presents an introduction to deep learning and various applications of deep learning such as recommendation systems, text recognition, diabetic retinopathy prediction of breast cancer, prediction of epilepsy, sentiment, fake news detection, software defect prediction and protein function prediction.

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Advertising culture and translation : From colonial to global

A first comprehensive study combining and integrating advertising, culture and translation within the framework of colonial, Commonwealth, and postcolonial studies, and globalization. It addresses a number of controversial issues evident in two relatively young disciplines, as a result of decades of research and teaching in university courses. A cross-cultural approach to translational issues and the translatability of advertising cohesively is adopted here, exploring the dynamics of the conflict between the 'centre' and the 'periphery'. It introduces the concept of advertising English as lingua franca (AELF), marking new trends in the domain of varieties of English around the world (VEAW). The data examined here show the ambivalent polarity conditioning advertising and translation: both have been mutually exclusive, and both have been subject to bans, censorship and ideological control, racism, propaganda, and stereotyping. In their fundamental principles and concepts of theories and applications, however, neither discipline cannot exist outside a free market and total freedom of expression and trust

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Characterisation in Federations : Six Countries Compared

In this work Dr. Taylor surveys the federal countries of the world and asks how they divide power among the constituent units of the federation. In so doing, he considers not only the formal constitutional text, but, far more importantly, the case law that has grown up around it as the Courts develop approaches to interpreting provisions for the distribution of powers. This enables conclusions to be drawn about the effectiveness of various structural and interpretative approaches to the distribution of powers within federations.

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Case-Based Reasoning on Images and Signals

This book is the first edited book that deals with the special topic of signals and images within Case-Based Reasoning (CBR). It offers different learning capabilities, for all phases of a signal-interpreting system, that satisfy different needs during the development process of a signal-interpreting system.

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Carotenoids ; Vol.4 : Natural Functions

The Carotenoids book series provides detailed accounts of the fundamental chemistry of carotenoids and the basic methods used in carotenoid research, and critical discussions of the biochemistry, functions and applications of these important compounds. Volume 4 and its companion, Volume 5, deal with the functions of carotenoids in all kinds of living organisms and the actions of carotenoids in human nutrition and health. The material presented in the earlier Volumes is all relevant to studies of biological functions and actions. In particular, biological studies must be supported by a rigorous analytical base. The various analytical procedures described in Volumes 1A and 1B, supplemented by the data for individual compounds given in the Carotenoids Handbook, must be understood and applied correctly, whether they are being used for quantitative analysis, identification or in complex studies of carotenoids in situ.

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