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Manufacturing of Pharmaceutical Proteins: From Technology to Economy

Manufacturing of Pharmaceutical Proteins: From Technology to Economy, renowned chemical engineer Dr. Stefan Behme delivers a comprehensive text covering all aspects of biopharmaceutical manufacturing, including legal and regulatory considerations, production facility design, quality assurance, supply chain management, emerging market regulations, and cost control.

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Manuale di accreditamento delle strutture diabetologiche = Accreditation manual of diabetic facilities

Healthcare quality is not a new issue, but it is often underestimated. The doctor focuses on his relationship with the patient, and is led to believe that technique and technology are sufficient to guarantee effective and efficient performance, regardless of the organizational system. Quality understood as "Total Quality Management" is a way to cross a border, to create knowledge, to break the armor of self-referentiality and that individualistic vision of work learned during university studies and consolidated by professional practice. The path of professional peer accreditation is the tool that the scientific society Associazione Medici Diabetologi has developed and provided to diabetologists to facilitate the understanding of ways of looking at the world of healthcare that are different from those they usually use.

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Living Rivers : Trends and Challenges in Science and Management

All over the world, sustainable river basin management is a leading principle of policy plans and legal instruments for water management (e.g. the European Water Framework Directive). The evidence, however, to underpin the full scope of sustainability is rather scanty. In this book an integrative perspective on trends and challenges in river science and management is demonstrated. The three pillars underneath sustainable water management, ecology, economy and sociology, are elaborated by experts in their fields. A number of papers integrate the current knowledge on the structure, functioning and management of ‘living rivers’. The book includes data and experiences concerning the rivers Allier, Meuse, Rhine, Sava and Tagliamento in Europe and the river Illinois in the USA. Sustainable river basin management asks for un-orthodox rehabilitation programmes and ecosystem based and transboundary management approaches.

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Liver and Pancreatic Diseases Management

New therapeutical approaches, advances in oncology and in diagnostic imaging, which reduce the need for invasive techniques and reach an improvement in survival and quality of life in cancer, are considered in this book. Modern literature has been reviewed with special reference to articles of general interest. In the clinical management of patients with liver, bile duct and pancreas diseases, it is important to assess the degree of disturbance and to diagnose the causative insult, and therefore clinical and laboratory methods of assessing each of these pathologies are of high interest. This version is an up-to-date account of diseases of the liver, biliary tract and pancreas, including transplantation, which we trust will be of value for surgeons, physicians and pathologists and also a reference book for medical students.

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Lifestyle psychiatry through the lens of behavioral medicine

Lifestyle medicine is a practice which adopts evidence-based lifestyle interventions as a primary modality to prevent, treat, and reverse chronic diseases. The six main pillars of this specialty include physical activity, nutrition, stress resilience, cessation or risk reduction of substance use, quality sleep, and connectivity. Lifestyle psychiatry is a rapidly emerging area within healthcare informed by rigorous research within the social and biological sciences, public health, and medicine. A volume in the Lifestyle Medicine series, this book uses a comprehensive biopsychosocial approach to prevent and treat psychiatric disorders and promote mental and physical well-being through evidence-based lifestyle interventions.

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Les prothèses tricompartimentaires du genou de première intention : Techniques opératoires. Problèmes et solutions = Primary tricompartmental knee replacement : Surgical techniques, problems, and solutions

It seems difficult and presumptuous to want to write a book on total knee replacement. There are many quality works dealing with this subject. The knee prosthesis has, from its origin, particularly in the United States, given rise to considerable studies in all directions: biomechanical, physiological, biological and industrial. Our goal is to offer the youngest a book of simple knowledge without pretension of completeness or prejudice as to long debated subjects (conservation or not of the posterior cruciate ligament, cement or without cement, resurfacing or not of the patella, fixed plate or mobile platform, etc.), and to give practical advice based on our experience. Why limit yourself to first-line tricompartmentals? Because it is the most common solution to the usual degenerative knee problems. In addition, unicompartment and revision prostheses will be the subject of further literature. Everyone knows that to put a knee prosthesis model, and therefore to a system. However, it is important to be able to keep your freedom of analysis in order to maintain your freedom of choice. You have to know how to put on a knee prosthesis without compromise or fanaticism. Convictions are more dangerous enemies of truth than lies. Nietzsche

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Lentil : An ancient crop for modern times

Presents the most comprehensive and up to date review of research on lentil production systems, biotic and abiotic stresses management, quality seed production, storage techniques and lentil growing around the world. This book will be of great value to legume breeders, scientists, nutritionists, academic

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Le dépistage du cancer du sein : un enjeu de santé publique = Breast cancer screening: a public health issue

Fifteen years after the first experiments, the breast cancer screening program was rolled out in France in 2004. It is aimed at more than eight million women aged 50 to 74. Public health action on such a scale is exemplary in Europe and especially in France where the health system is not centralized. The new edition of this book takes stock of the current state of the program and its initial results. It updates technical and radiological aspects, assessment indicators, communication and forensic problems and finally the progress of foreign programs. The history of the French program is detailed from the 1990s until 2006, with the publication of the latest version of the specifications by the Directorate General of Health. The short and medium term objectives are re-specified: to increase the participation of women, to retain them and to further improve the quality of practices. The challenge is to combine the performance of screening and therapeutic management to finally achieve a clear reduction in mortality, which has remained stable for twenty years.

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Lapproccio e la gestione per processi in pneumologia = The process-based approach and management in pulmonology

The topics covered are highly relevant to the application of the methods and tools outlined in quality improvement programs. This is in an effort to enhance the specific skills of the pulmonologist, thus making him an effective and independent liaison with the relevant strategic management. With great sensitivity, the SIMeR (Italian Society of Respiratory Medicine) has chosen to sponsor this edition, the only one to date in the field of Pulmonology, whose contents are based on the proposals and work of the leaders of one of its most recently established Study Groups, the "Continuous Quality Improvement in Pulmonology" Study Group.

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Landscape Pattern Analysis for Assessing Ecosystem Condition

Landscape Pattern Analysis for Assessing Ecosystem Condition presents a new method for assessing spatial pattern in raster land cover maps based on satellite imagery in a way that incorporates multiple pixel resolutions. This is combined with more conventional single-resolution measurements of spatial pattern and simple non-spatial land cover proportions to assess predictability of both surface water quality and ecological integrity within watersheds of the state of Pennsylvania (USA).

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Laboratory control system operations in a GMP environment

In Laboratory Control System Operations in a GMP Environment, readers are given the guidance they need to implement a CGMP compliant Laboratory Control System (LCS) that fits within Global Regulatory guidelines. Using the Quality Systems Approach, regulatory agencies like the FDA and the European Medicine Agency have developed a scheme of systems for auditing pharmaceutical manufacturing facilities which includes evaluating the LCS.

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Community Health Cares O-Process for Evaluation : A Participatory Approach for Increasing Sustainability

Community Health Care’s O-Process for Evaluation offers step-by-step assistance in achieving these goals, from determining areas for assessment to disseminating the results. The steps can be conducted in-house or adapted for use with outsiders, laying a solid foundation for a cycle of continuous evaluation and continued improvement for long-term sustainability.

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Clinical nuclear medicine

Clinical Nuclear Medicine … focuses on the universal state of the art in both diagnostic and therapeutic radionuclide methodology. … This book is easily readable, with presentation of essential points and plentiful references, and the quality of the figures and tables is excellent. … is a useful guide to students, technologists, and practitioners in nuclear medicine and radiology, as well as to general physicians who request nuclear diagnosis or treatment. … will be a welcome contribution to the bookshelf of nuclear medicine or radiology clinics.

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Clinical decision support systems : Theory and practice

Writes the editor, "If used properly, CDSS have the potential to change the way medicine has been taught and practiced." As clinical decision support systems (CDSS) gain an increasingly central role in the delivery of high quality health care, it becomes more important for the health care community to understand their use. This text is designed as a resource for practicing clinicians, informaticians, teachers and students alike, and provides the most current, comprehensive look a the development and evaluation of clinical decision support systems.

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Clinical Blood Pool MR Imaging

MR Angiography covers the basic techniques, safety, efficacy, image processing and pharmaco-economic details to successfully implement a new level of MRA image quality with this new contrast agent.

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Cleaning validation : Practical compliance approaches for pharmaceutical manufacturing

Timely coverage of cleaning validation for the pharmaceutical industry, a dynamic area in terms of health-based limits. Encourages pharmaceutical manufacturers, and particularly upper management, to meet the challenges of the science-based and riskbased approaches to cleaning validation. Draws on the author’s vast experience in the field of cleaning validation and hazardous materials. Discusses EMA vs. ISPE on Cleaning Limits and revised Risk-MaPP for highly hazardous products in shared facilities. A diverse list of topics from protocol limits for yeasts and molds to cleaning validation for homeopathic drug products.

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Chronic diseases and health care : New trends in diabetes, arthritis, osteoporosis, fibromyalgia, low back pain, cardiovascular disease, and cancer

CHRONIC DISEASES AND HEALTH CARE: New Patterns of Diabetes, Arthritis, Osteoporosis, Fibromyalgia, Low Back Pain, Cardiovascular Disease, and Cancer. This book evaluates new trends in epidemiology, health care costs, risk factors, treatment and rehabilitation outcomes, stress and coping strategies, social support, disability, patient education, and self-management for seven prevalent chronic diseases.

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Choices in Palliative Care : Issues in Health Care Delivery

Keeping up with these statistics means improving on traditional concepts of palliative care to meet growing demands. Choices in Palliative Care brings together 31 leading experts to spotlight core issues in the field, identify ways PC can fill gaps in current care systems, and demonstrate state-of-the-art care that is both cost-effective and clinically appropriate. This far-sighted volume redefines palliative care as interdisciplinary and integrative, providing liaisons between patients, families, and doctors; minimizing loved ones’ care burdens; bridging acute and long-term care to respond to clients’ evolving needs; adaptable to non-fatal (and possibly curable) chronic illnesses.

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Chemometrics and Cheminformatics in Aquatic Toxicology

Chemometrics and Cheminformatics in Aquatic Toxicology delivers an exploration of the existing and emerging problems of contamination of the aquatic environment through various metal and organic pollutants, including industrial chemicals, pharmaceuticals, cosmetics, biocides, nanomaterials, pesticides, surfactants, dyes, and more. The book discusses different chemometric and cheminformatic tools for non-experts and their application to the analysis and modeling of toxicity data of chemicals to various aquatic organisms.

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Chemical and functional properties of food components

Described the contents of food raw materials and products, the chemistry/biochemistry of food components, as well as the changes occurring during post-harvest storage and processing affecting the quality of foods. Discusses the role of chemical compounds in the structure of raw materials and the formation of different attributes of food quality, including nutritional value, safety, and sensory properties. It contains four new chapters: “Non-Protein Nitrogenous Compounds”; “Prooxidants and Antioxidants in Food”; “Non-Nutritive Bioactive Compounds in Food of Plant Origin”; and “Analytical Methods Used for Assessing the Quality of Food Products.”

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