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A History of Physical Theories of Comets, From Aristotle to Whipple

The book describes the major physical theories of comets in the past two millennia. It demonstrates the evolution of ideas about the nature, position, motion and physical constitution of comets from Aristotle to Whipple. Unlike the available works on the history of comets, which either illustrate relatively short periods in the history of physical cometology or portray a landscape view without adequate details, the present study focuses on details of each theory. It also investigates the interaction between observational and mathematical astronomy, and the physical sciences in defining the properties of comets.

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Marine Biodiversity : Patterns and Processes, Assessment, Threats, Management and Conservation

Understanding the functioning of Marine Ecosystems is the first step to measure and predict the influence of Man, and to find solutions for the enormous array of problems we face today. This volume is organised according to the four subthemes of the symposium and to issues commonly perceived as relevant by scientists concerned with the study, protection and management of Marine Biodiversity: patterns and processes, assessment, threats and management and conservation.

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Long-Term Ecosystem Changes in Riparian Forests

Presents and analyzes the results of more than 30 years of long-term ecological research in riparian forest ecosystems with the aim of casting light on changes in the dynamics of riparian forests over time.

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Liver Immunology : Principles and Practice

parasitic and viral infections of the liver, autoimmune liver disease, alcoholic and nonalcoholic fatty liver diseases, and transplantation in an easy-to-read and thorough format. Authors also address the key issues that have arisen in this field in recent years, including physiological roles of hepatocytes, sinusoidal lining cells, activated macrophages (Kupffer cells), cholangiocytes and stellate cells, and their modulation of T cells, natural killer (NK) cells and NKT cells.

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Liver and Biliary Tract Surgery : Embryological Anatomy to 3D-Imaging and Transplant Innovations

The book also covers cutting-edge research and technological advances that will shape the surgery of tomorrow. There is little doubt that technological advances in preoperative imaging, such as 3-D reconstruction, preoperative preparation with portal vein embolisation and operative techniques using bloodless RF resection methods, are already changing the nature of liver surgery.

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Life as We Know It

Life As we Know It ["LAKI"] covers several aspects of Life, ranging from the prebiotic level, origin of life, evolution of prokaryotes to eukaryotes and finally to various affairs of human beings. Although it is hard to define Life, one can, however, characterize it and describe its features. Topics treated are categories of bacteria, algae and fungi, conscience, philosophy, theology, aesthetics, appearance of sport and life destiny, life after clinical death, and thoughts of the world to come ("Olam Haba"). The various chapters have been written so that they are accessible to all - from the avid lay reader to the specialist – and make available multidisciplinary sources of information about Life. This volume will interest open minded scholars, students at all levels of general sciences, natural and Life science, researchers of philosophy, theology, history of Life, astrobiology, and those who wish to widen their knowledge about "who are we in the universe".

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Les thérapies ciblées = Targeted therapies

We are at the start of the development of new therapeutic classes, directed against new molecular targets (EGFR, VEGF, IGFR, Rank, etc.) Several diseases such as kidney, colon or breast cancer, GIST, have a natural history now modified thanks to these therapies. This practical book takes stock of the current use of these molecules.

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Legionella Pneumophila : Pathogenesis and Immunity

Legionella pneumophila is an emerging human pathogen that resides in natural environments as a parasite of freshwater. The volume brings together all of the lastest research on this pathogen, the interest in which is rapidly growing.

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Le dépistage du cancer du col de lutérus = Cervical cancer screening

Each year, cervical cancer kills approximately 1,000 people in France, making it the fifth leading cause of cancer death and the eighth most common cancer among women. While eradicating cervical cancer is not possible, a national screening campaign should significantly reduce its incidence. This campaign should be based, in particular, on the systematic use of Pap smears. Conventional Pap smears have already reduced the number of invasive cancers by more than 50%. Improving them requires optimizing their sensitivity. This book details the natural history of cervical cancer, its incidence and mortality, and the various aspects of screening: general principles, the French screening program, the different types of Pap smears, the role and contribution of the HPV test, the management of abnormal Pap smears, the role of colposcopy, and the follow-up of treated women. It is intended for all those involved in this screening : specialist interns and gynecologists, pathologists and biologists, public health physicians, but also general practitioners whose role in screening is privileged since they are at the forefront of medical demand.

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Landscape Ecological Applications in Man-Influenced Areas : Linking Man and Nature Systems

This book also includes several case studies concerning landscape analysis and evaluation using spatial analysis and landscape modelling for establishing sustainable management strategy in urban and agricultural landscapes. The subtitle of the book suggests the integrative and ubiquitous landscape planning considering harmony of man and nature systems in the socio-economic and cultural background.

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La riabilitazione dei disturbi cognitivi nella sclerosi multipla = The rehabilitation of cognitive disorders in multiple sclerosis

Multiple sclerosis is one of the most frequent causes of chronic disability in young adults. It mainly affects individuals between 20 and 50 years of age, with a peak of incidence around the age of 30. This disease is characterized by the presence of demyelinating lesions of an inflammatory nature disseminated in the central nervous system. The different localization of these lesions is at the basis of the variability of clinical symptoms which can be characterized by motor, sensory, neurovegetative and cognitive disorders. The latter concern about half of the patients affected by this pathology and have a significant impact on the personal, family and work situation of these patients.

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La phytocosmétologie thérapeutique = Herapeutic phytocosmetology

Deals with restorative cosmetology. This is understood through the eyes of the doctor specializing in phytotherapy. Three main aspects are discussed: the diagnosis of disturbance of the skin and integuments, external treatment with natural substances, as well as oral treatment (internal treatment). Oral cosmetology has no official recognition, yet the effects of plant extracts on the condition of the skin and integuments are well known. After an introduction to the physiology of the skin, the dosage and the phenomena of skin deterioration, the author discusses different types of treatment depending on the extracts used while explaining their mode of action. This work was written by a doctor, Doctor Paul Goetz, teacher in clinical phytotherapy, and a pharmacist, Doctor Christian Busser, pharmaceutical and scientific advisor, doctor in ethnology and ethnopharmacologist.

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La colografia virtuale con TC multistrato (CTC) = Virtual colonography with multislice CT

With the spread of multidetector row CT (MDCT), virtual colonography (VC) is establishing itself as a new, proven alternative radiological method in the diagnosis of intestinal polyps and colorectal cancer. VC is already considered the first-line examination for identifying synchronous tumor lesions in patients with colorectal cancers that cannot be penetrated by endoscope, simultaneously providing accurate staging of malignant lesions. Its minimally invasive nature makes VC a valid alternative to pancolonoscopy, even in the detection of intestinal polyps, and provides the basis for interesting developments regarding future applications in screening programs. The text, aimed at radiologists who are approaching the method, radiology technicians and doctors involved in the diagnostic and therapeutic process of colorectal pathology, indicates the advantages of the normal method, the normal method with fourteen chondrii, the normal method with fourteen chondrii, the pathological method with fourteen chondrii indications.

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Clinical microbiology made ridiculously simple

Is a brief, clear, thorough, and updated approach to clinical microbiology, brimming with mnemonics, humor, summary charts, and illustrations. Topics include Ebola, AIDS, flesh-eating bacteria, mad cow disease, hantavirus, anthrax, smallpox, and tuberculosis; the latest antibiotics; pandemic flu, including H7N9; SARS-like coronavirus; hepatitis C treatment options; HIV diagnostics and approved HIV meds; Zika virus; measles; and a new chapter on the latest emerging infectious diseases and drug-resistant bacteria. The major update to this book is the addition of a new chapter on the SARS-COV-2 virus and COVID-19 disease, which delves into the nature of the virus such as infectivity within the body, transmission between individuals, timeline of infectivity, symptoms, risk factors, therapeutics, and vaccines approved for use.

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Classics in total synthesis IV : new targets, strategies, and methods

A compilation of highly important synthetic methods which lead to complex molecules with valuable properties. From the complex architectures of natural products to the streamlined synthesis of functional molecules, each chapter in Classics in Total Synthesis IV unfolds a unique story. The interplay of mechanisms, reactivity, selectivity, and stereochemical aspects is thoroughly examined, echoing the pedagogical format that has become synonymous with this series. Well-designed graphics are included throughout, and all important parts of the reaction sequences are highlighted.

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Classical Biological Control of Bemisia tabaci in the United States : A Review of Interagency Research and Implementation

This book reviews the interagency research and development effort on classical biological control in the USA from 1992-2002. The successful exploration, importation, screening, evaluation, rearing, and establishment of at least five exotic Bemisia. tabaci natural enemies in rapid response to the devastating infestations in the USA is a landmark in interagency cooperation and coordination of multiple disciplines. In this volume, the various authors present detailed reviews of natural enemy exploration, introduction, and evaluation efforts that will serve as a guide to support and encourage classical biological control inputs into other integrated pest management systems.

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Chromatin and Disease

It is more evident now than ever before that dynamic organization of human genome into nucleoprotein structure, chromatin confers the unique regulatory mechanisms for most of the cellular phenomena, which include replication, transcription, DNA repair, recombination and also apoptosis. The dynamic nature of the chromatin is regulated by chromatin modifications (epigenetic alterations), remodeling, histone chaperones and functional interactions of different chromatin interacting n- histone proteins. Dysfunction of this highly inter connected machineries disturb the cellular homoeostasis, and thereby causes several diseases. As we advance in our knowledge of chromatin function and also disease mechanisms in more details, their causal relationship is becoming more evident. This has lead to the identification of chromatin function as target for new generation therapeutics.

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Chemistry of natural products : phytochemistry and pharmacognosy of medicinal plants

Plants produce secondary metabolites that humans harness for their own benefit. About half of drugs currently in clinical use are based on these chemicals found in nature. Chemistry of Natural Products covers secondary metabolites present in medicinal plants and their biosynthesis, biological activities, and isolation and separation techniques.

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Chemistry of Biologically Potent Natural Products and Synthetic Compounds

Several novel natural product derivatives, heterocyclic and other synthetic compounds, have been reported to have shown interesting biological activities including anticancer, antimicrobial, anti-inflammatory, anti-glycemic, anti-allergy and antiviral etc. Provides up-to-date information on new developments and most recent medicinal applications of the natural products and derivatives, as well as the chemistry and synthesis of heterocyclic and other related compounds.

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Cell-Cell Channels

The biological sciences are dominated by the idea that cells are the functionally autonomous, physically separated, discrete units of life. This concept was propounded in the 19th century by discoveries of the cellular structuring of both plants and animals. Moreover, the ap­ parent autonomy of unicellular eukaryotes, as well as the cellular basis of the mammalian brain (an organ whose anatomy for a long while defied attempts to validate the idea of the cellular nature of its neurons), seemed to provide the final conclusive evidence for the completeness of *cell theory', a theory which has persisted in an almost dogmatic form up to the present day. However, it is very obvious that there are numerous observations which indicate that it is not the cells which serve as the basic units of biological life but that this property falls to some other, subcellular assemblage. To deal with this intricate problem concerning the fundamental unit of living matter, we proposed the so-called Cell Body concept which, in fact, devel­ ops an exceedingly original idea proposed by Julius Sachs at the end of the 19th century. In the case of eukaryotic cells, DNA-enriched nuclei are intimately associated with a microtubular cytoskeleton. In this configuration—as a Cell Body—these two items comprise the fundamental functional and struc­ tural unit of eukaryotic living matter. The Cell Body seems to be inherent to all cells in all organisms.

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