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Zoonosi e sanità pubblica : Un approccio interdisciplinare per un problema emergente = Zoonosis and Public Health: An Interdisciplinary Approach to an Emerging Problem
Zoonoses, that is, naturally transmissible infections between other animal species and man, are now an emerging problem, even in developed countries. Climate change, human migration flows, growth in international trade and wars favor both the re-emergence of diseases considered rare and the introduction of potentially pathogenic organisms into new geographical areas. For most of these pathologies, however, the majority of health professionals - starting with general practitioners - often do not have appropriate and up-to-date knowledge and tools. The text aims to provide medical personnel - and primarily general practitioners - with both a scientific and regulatory framework and a series of specific and practical information on individual pathologies. This volume is intended to be an operational tool also aimed at encouraging multidisciplinary collaboration and the exchange of information, in particular between doctors and veterinarians.
Wound antiseptics in nosocomial infections
"Nosocomial" term is used for any disease acquired by patient under medical care. It is an infection acquired by patient during hospital stay. Recently, a new term, "healthcare associated infections" is used for the type of infections caused by prolonged hospital stay and it accounts for a major risk factor for serious health issues leading to death
Vitamin E in Human Health
Examines the role of vitamin E as an essential micronutrient in human health and its extensive clinical benefits. Sections cover a wide breadth of topics, including vitamin E intake and recommended daily allowance, understanding the biological activities of Vitamin E and observed physiological effects, benefits of vitamin E on upper respiratory infections, cardiovascular disease, age-related macular degeneration, Alzheimer’s disease, and intake safety. The text serves to emphasize the importance of vitamin E in relation to disease prevention as well as to raise awareness of the number of health conditions where an increased intake of vitamin E can be of potential significance. It explores vitamin E in an up-to-date, science based, applicable real-life perspective and offers pragmatic solutions for its safe and personalized use beyond the various methodological and statistical controversies.
Viral Membrane Proteins: Structure, Function, and Drug Design
Protein Reviews, a new book series from Springer, covers all aspects of protein investigations including protein chemistry, sequence, 3-D structure, biological activity, proteomics, methodology, and many more new and emerging topics. This book can help teach everyone that it is possible to treat viral disease with drugs that bind to membrane proteins. Knowing that, we can hope that more resources will be focused on finding other such drugs to the remaining scourges of mankind, at least those we do not produce ourselves."
Uncertainty Assessment of Large Finite Element Systems
The treatment of uncertainties in the analysis of engineering structures remains one of the premium challenges in structural mechanics. It is only in recent years that the developments in stochastic and deterministic computational mechanics began to be synchronized. In this monograph novel computational procedures for the uncertainty assessment of large finite element systems are presented. The procedures are applicable to well known problems in computational stochastic mechanics, such as the stability analysis of systems with random imperfections and the dynamic analysis of deterministic systems under stochastic loading. For the dynamic analysis of deterministic systems under stochastic loading, an efficient procedure based on the Karhunen-Loève representation of the response is presented. The capabilities of the developed procedures are demonstrated with several numerical examples.
Tropical and Parasitic Infections in the Intensive Care Unit
In the past, many tropical and parasitic infections were confined to tropical areas of the world located between the Tropic of Cancer and the Tropic of Capricorn. However, with the increase in air travel and tourism and the changing patterns of immigration, an increasing number of individuals are coming into contact with these infectious agents and transmission across the world has been enhanced. Tropical and Parasitic Infections in the Intensive Care Unit provides an international perspective on this topic and an overview of those infections that may cause critical illness.
Traité des infections et pathologies génitales à papillomavirus = Treated on genital papillomavirus infections and pathologies
The impact of papillomavirus (HPV) infection is considerable. More than one in two women has been exposed to HPV in her lifetime and about 10% will develop a chronic infection. Of these, 20% will develop cervical cancer in the absence (or failure) of screening. Optimization of screening and better management are now possible through the use of innovative techniques such as smear in liquid suspension and HPV testing. Because cervical cancer is the ultimate consequence of chronic HPV infection, we now have the extraordinary chance to prevent it with a prophylactic vaccine intended to protect women from the associated precancerous and cancerous HPV lesions, as well as condylomata acuminata. This resolutely practical and educational collective work takes stock of knowledge on HPV infection and its associated pathologies while deciphering the new issues and practices in the vaccine era.
Traité dandrologie à lusage des cliniciens = Andrology treatise for clinicians
This book is the French translation of a reference book Andrology for the clinicians. It has two parts. The first part is directly related to current practice in andrology: the diagnosis and resolution of the problem. In this part, the busy clinician will easily find information oriented towards the problem he is facing in situations such as: fertility problems due to a male factor / ejaculatory, sexual and orgasmic dysfunctions / tumors and infections of the male genital tract / male contraception / male aging.
Topical treatments of skin infection
A hospital-acquired infection, also known as a nosocomial infection, is an infection that is usually transmitted after hospitalization and appears within 48 hours of hospitalization. Bacteria, fungi, and viruses can cause deep infections in healthcare. Bacteria alone cause about 90 percent of these cases, and there are many types of HAI including SSI, which is defined as an infection that occurs up to 30 days after surgery and affects either the incision or the deeper tissues in the operation...
Therapeutic Dressings and Wound Healing Applications
Takes a clinical and scientific approach to wound healing, and includes recent case studies to highlight key points and areas of improvement. It is divided into two key sections that include insight into the biochemical basis of wounds, as well as techniques and recent advancements. Chapters include information on: Debridement and disinfection properties of wound dressing / Biofilms, silver nanoparticles, and honey dressings / Clinical perspectives for treating diabetic wounds / Treating mixed infections / Wound healing and tissue regeneration treatments / Gene based therapy, 3D bioprinting and freeze-dried wafers
The silent epidemic
Biofilm is a complex structure of microbiome having bacterial colonies adhere to the surface. These cells are embedded in extracellular polymeric substances, a matrix generally composed of eDNA, proteins and polysaccharides, showing high resistance to antibiotics. Quorum sensing plays an important role in regulating the biofilm formation. Biofilm is one of the major causes of infection persistence especially in nosocomial settings through indwelling devices. There are many approaches being used to control biofilm. Indeed, the adhesive characteristics of natural human flora are now considered as a tool for preventing the adhesion of pathogenic bacteria to avert infection. These antibiofilm approaches represent a promising therapeutic target in the treatment of biofilm infections and development of a strong capability to interfere with different phases of the biofilm development.
The Physics of Structural Phase Transitions
This book is divided into two parts. The first part includes such topics as the Landau theory of phase transitions, statistics, correlations, and the mean-field approximation, pseudospins and their collective motion, soft lattice modes, condensates and their nonlinear growth, and lattice imperfections and their role in phase transitions of real crystals. The second part discusses experimental studies of modulated crystals using X-ray diffraction, neutron inelastic scattering, light scattering, dielectric measurements, and magnetic resonance spectroscopy. While the presence of modulated structures in the critical region is not particularly suggested in the published results of these studies, it is notable that most observed anomalies indicate evidence for pinned pseudospin condensates.
The periodontic-endodontic interface
Discusses embryonic development of the tooth, oral health and pathology, as well as the diagnosis and management of periodontal disease and endodontic disease, occurring both separately and together. Evidence-based information is given on Periodontal and Endodontic pathogens, lesions and infections with various forms of manifestation. It complemented by numerous high-quality photographs and tables that assist understanding and helps with the identification of management solutions.
The Papillomaviruses
This volume reviews the remarkable confluence of science, medicine, and public health that recently culminated in the approval of vaccines that prevent many human papillomavirus infections, the first vaccines specifically designed to prevent human cancer. Basic laboratory studies of viral DNA replication, gene expression, protein function, and virus-host interactions have provided fundamental insights into these important processes.
The Neurological Manifestations of Pediatric Infectious Diseases and Immunodeficiency Syndromes
World Health Organization data documents that infectious diseases and immunodeficiencies are the leading causes of morbidity and mortality in the world's children. In The Neurological Manifestations of Pediatric Infectious Diseases and Immunodeficiency Syndromes, an authoritative, international panel of experts provide a succinct, up-to-date, evidence-based reference to the neurological consequences of infectious diseases and immunodeficiency syndromes in children in one readily accessible volume. Within each of its conveniently structured chapters, readers will find a general description of the disease or disorder, its epidemiology, etiology, clinical synopsis, neurological manifestations, diagnosis, differential diagnosis and therapy.
The EBMT handbook : Hematopoietic cell transplantation and cellular therapies
Addresses the latest developments and innovations in hematopoietic cell transplantation and cellular therapy. Consisting of 94 chapters, it has been written by 210 leading experts in the field. Discussing all types of hematopoietic cell transplantation, including selection of stem cell sources, it also covers the indications for transplantation, the management of early and late complications as well as the new and rapidly evolving field of cellular therapies and new infections (COVID-19).
The Biology of Dendritic Cells and HIV Infection
This comprehensive volume, written by experts in the field, is the first to address the biology of dendritic cells (DCs) in an integrated fashion, in the context of HIV infection and immunity. The book brings together the most recent information related to the biology of DCs and their role in the pathogenesis and immunity of HIV-1 infection. Recent research in immunology has revealed the key importance of DCs in the regulation of the immune response to infections and that DCs are important targets and reservoirs of HIV, playing a critical role in several aspects of viral pathogenesis and immunity. The Biology of Dendritic Cells and HIV Infection is an ideal book for researchers, clinicians, physicians, and graduate students in the fields of basic and applied immunology, virology, cell biology and vaccine development.
The 5Ds of Stewardship
Antibiotic resistance (ABR) has been identified as a critical threat to global health. A leading cause of ABR is the inappropriate use of antibiotics by both patients and healthcare providers led to the development of antibiotic resistance and a rise in harms related to antibiotics, including antibiotic associated adverse events and Clostridioides difficile infections...
Surgery : Basic Science and Clinical Evidence
Fully revised and updated information on the evidence-based practice of surgery, significant new sections on trauma and critical care on the often challenging surgical care of unique populations; (elderly, pediatric, immunocompromised, and obese patients). The internationally recognized editors and authors have maintained their evidence-based approach throughout the text with thoughtful and timely new chapters on the pre- and post-operative care of the cardiac surgery patient, intestinal transplantation, surgical infections, the fundamentals of cancer genetics and proteomics, and discussions of electrosurgical instruments, robotics, imaging modalities, and other emerging technologies influencing the modern practice of surgery. The oft-cited chapter on the principles of evidence-based decision-making in surgical practice is completely updated for the second edition, presenting the reader with a framework for the evidence-based practice of surgery.
Strategy vs Tragedy in the Crown Era
Tragedy the world is now experiencing its third major epidemic of coronavirus infections. The novel coronavirus SARS-CoV-2, the causative agent of COVID-19, has quickly become a threat to the public health and economy worldwide. As of July 2020, more than 15 million people worldwide have been infected with SARS CoV-2, and COVID-19 has led to more than 600 000 deaths. Strategy currently, there is no specific therapeutic drugs targeting the SARS-CoV-2 and no specific therapeutic agents had demonstrated efficacy in treating patients with COVID-19. Until then, “repurposed” drugs that have been approved for other indications are being used to treat COVID-19 patients. Nevertheless, the efficacy of these treatment regimens remains to be verified by appropriately designed clinical trials.
