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Managing Your Headaches
Frequent headaches seriously affect the lives of millions of sufferers. The result can be lost productivity and income, restrict activity, lower self-esteem, and even social isolation. For many, it takes years to find the appropriate medication to manage your headaches effectively. In Managing Your Headaches, Mark and Leah Green and John Rothrock explain what information you should record for your physician, what a physician is looking for in a neurological examination, and what you should (and should not) do to reduce the frequency and severity of your headaches. They discuss the effects of stress, psychological factors, possible food triggers, and environmental risk factors. The authors explain the symptoms of migraine, cluster, and tension-type headaches as well as less common types. They address common concerns and misconceptions and explain current knowledge about headache causes in understandable terms. The newest, most effective medications and their possible side effects are evaluated. The authors also explain how to prevent rebound headaches from over-medications and how non-medical treatments can be of value. Managing Your Headaches will tell you what you need to know to better control your headaches. Armed with the information in this book, you can be aware of the latest treatment options and can have more productive, informed discussions with your physician.
Macrosocial Determinants of Population Health
Macrosocial Determinants of Population Health explores social factors such as culture, mass media, political systems, and migration that influence population health while systematically considering how we may best study these factors and use our knowledge from this study to guide public health interventions.Each section ends with Galea’s integrative chapters, bringing the observations and conclusions from the chapters into clear, usable focus. Macrosocial Determinants of Population Health is a work of major theoretical, empirical, and practical interest for disciplines as varied as public health, epidemiology, health promotion, sociology, and health policy. Its systematic field-building approach makes it as valuable to the public health provider as to the scholars and students studying the health of populations.
Lymphocyte Signal Transduction
Signal transduction through leukocyte receptors involves a variety of signaling molecules including kinases, phosphatases, adaptor proteins, small GTPases GTP exchange factors, membrane phospholipids as well as others. These signal transducers, regulated by inter- and intra-molecular interactions, as well as by various post-translational modifications, lead to the activation of transcription factors that mediate cellular differentiation and growth, effector cell functions, and apoptotic cell death. Several investigators from various parts of the world convened at the 3rd Lymphocyte Signal Transduction Workshop in Crete, Greece from May 27 to June 1, 2005 to discuss their most recent findings in leukocyte signaling. This volume represents a collection of topics discussed during the conference.
Listeria Monocytogenes : Pathogenesis and Host Response
This comprehensive volume, written by experts in the field, includes concise and timely reviews of Listeria monocytogenes, one of the most intensively studied bacterial pathogens. Listeria monocytogenes is the cause of listeriosis, a potentially fatal disease that arises from the consumption of contaminated food. During the past two decades, studies of this organism have uncovered a wealth of information on its virulence factors, its genome organization, and its interactions with host cells and the immune system.
Les infections urinaires = Urinary tract infections
Les Infections urinaires provides an update on knowledge concerning the epidemiology of community-based infection, on the mechanisms of bacterial resistance and on certain aspects of the disease useful to urologists as well as infectious diseases, gynecologists, emergency physicians and attending physicians. . Nosocomial urinary tract infection is approached from the perspective of risk factors. Acute and chronic prostatitis was the subject of a consensus conference supported by the World Health Organization within the framework of the International Consensus Conferences in Urology in Paris. The full text and the recommendations are reported with the consent of their authors. This book is an author's book and not an author's book because urinary tract infection is multiple, complex and justifies a multidisciplinary approach.
Les douleurs abdominales en questions : Rôle physiopathologique de la sensibilité viscérale = Abdominal pain in question : The pathophysiological role of visceral sensitivity
The gut-brain axis refers to the network of nerve pathways that connect the myenteric plexus, the veritable "gut brain," to the central nervous system. Nearly 80% of these neurons are sensory neurons, and the afferent pathways that transmit information from the digestive tract to the central nervous system play a crucial role in the physiological regulation of digestive functions, as well as in certain pathological conditions. A large majority of these sensations remain unconscious and give rise to reflex responses. Only those requiring a conscious response reach the level of awareness in a normal state (hunger, thirst, the urge to defecate). In pathological situations, the same is true for painful sensations of digestive origin. Functional bowel disorders are a frequent reason for consultation. Their pathophysiology is now based on a model integrating the various etiological factors around the brain-gut axis. These patients frequently present with visceral hypersensitivity, which manifests as an increased perception of digestive sensations, notably the onset of pain in response to stimuli that are not painful in normal subjects. Recognizing the role of visceral hypersensitivity has made it possible to explain the mechanism of action of medications used to treat functional bowel disorders and paves the way for the development of new molecules acting on digestive afferents. In this book, we will describe the anatomical and physiological basis for understanding the concept of visceral sensitivity and the role of digestive afferents in the pathophysiology of acute and chronic abdominal pain, particularly irritable bowel syndrome.
Le cancer du sein = Breast cancer
The reader will find there both a synthetic summary of the current state of knowledge of epidemiology, risk factors and pathological aspects as well as a presentation of the surgical aspects, in particular, of the new approach that constitutes the sentinel node procedure. Radiotherapy, in a practical view, is divided into essential clinical questions. The medical treatment is then discussed according to the different situations encountered on a daily basis. Particular attention is of course paid to recent data both with the contribution of hormone therapy and targeted therapies. Finally, the symptomatic treatments and especially the psychological care of these patients are not forgotten.
La lombalgie en 2007 : Aspects pratiques = Low back pain in 2007 : Practical aspects
Low back pain is one of the main reasons for consultation, whether in general or specialized medicine. It poses a real public health problem. This "back pain", which can despair patients and doctors by its sometimes rebellious character, explains the multiplicity of examinations sometimes practiced and the treatments implemented. This work is a collection of the most recent developments in terms of physiopathological knowledge of disc involvement, clinical examination and the place of surgery and in particular disc prostheses. An update concerns the indications and contributions of additional examinations; some formidable diagnostic traps are mentioned. Medical treatments such as infiltrations, manipulations, the benefit of restraints and the provision of acupuncture are being developed. Also discussed are the latest scientific data on isokinetic evaluation and retraining, as well as the role of sports activity as a factor in the prevention or aggravation of low back pain. Finally, the medico-legal aspect is dealt with in the context of work accidents, and the assessment after trauma. This book is the result of the collaboration and experience of undisputed specialists in this field.
Complement and Kidney Disease
It is evident that a defective or deregulated complement system results in kidney diseases. An important role of complement effector and regulatory proteins in pathological settings of the kidney has been demonstrated. A large panel of distinct human kidney diseases is caused by defective complement control. Genetic analyses have identified mutations in complement regulators that are associated with these diseases. Mutations have been identified in the fluid phase alternative pathway regulator Factor H and the membrane regulator Membrane Cofactor Protein MCP (CD46). The functional characterization of the mutant proteins allows to define the pathophysiological events on a molecular level. These new concepts and data on disease mechanisms allowed establishing new diagnostic and promising therapeutic approaches for several human kidney diseases. Molecular biology, clinics and therapy are discussed in this volume.
Comparative Placentation : Structures, Functions and Evolution
Science produces fascinating puzzles: why is there such a range of placental structures when other mammalian organs are so structurally uniform ? Why and how did the different placental structures evolve ? Comparative placental studies can facilitate the identification of the common factors in placental growth, differentiation and function and their relevance to possible evolutionary pathways. Comparative Placentation is the only book presenting up-to-date data illustrating the great variety of structure but uniform function of vertebrate placentas from fish to man. This information is essential for selection of suitable models to investigate particular practical problems of impaired or anomalous growth in human and animal placentation. The unique collection of the best light and electron micrographs from the last thirtyfive years which precisely illustrate the structural range in each taxon, make the book the most authoritative publication in this field and a vital source of information for anyone interested on reproductive physiology, anatomy and medicine.
Clinical microbiology made ridiculously simple
Is a brief, clear, thorough, and updated approach to clinical microbiology, brimming with mnemonics, humor, summary charts, and illustrations. Topics include Ebola, AIDS, flesh-eating bacteria, mad cow disease, hantavirus, anthrax, smallpox, and tuberculosis; the latest antibiotics; pandemic flu, including H7N9; SARS-like coronavirus; hepatitis C treatment options; HIV diagnostics and approved HIV meds; Zika virus; measles; and a new chapter on the latest emerging infectious diseases and drug-resistant bacteria. The major update to this book is the addition of a new chapter on the SARS-COV-2 virus and COVID-19 disease, which delves into the nature of the virus such as infectivity within the body, transmission between individuals, timeline of infectivity, symptoms, risk factors, therapeutics, and vaccines approved for use.
Chronic diseases and health care : New trends in diabetes, arthritis, osteoporosis, fibromyalgia, low back pain, cardiovascular disease, and cancer
CHRONIC DISEASES AND HEALTH CARE: New Patterns of Diabetes, Arthritis, Osteoporosis, Fibromyalgia, Low Back Pain, Cardiovascular Disease, and Cancer. This book evaluates new trends in epidemiology, health care costs, risk factors, treatment and rehabilitation outcomes, stress and coping strategies, social support, disability, patient education, and self-management for seven prevalent chronic diseases.
Chromatin Dynamics in Cellular Function
This volume includes timely reviews of several aspects of chromatin biology written by scientists at the forefront of this rapidly moving field. Topics covered include the structure and function of protein modules within chromatin-remodeling proteins, newly characterized histone modifications (methylation, ubiquitylation) and their functional consequences, transcription and histone dynamics, roles of chromatin remodeling factors in DNA replication and repair, and current models of nucleosome-remodeling mechanisms.
Chemical Signals in Vertebrates 11
Presents the proceedings of "Chemical Signals in Vertebrates 11", hosted by the University of Liverpool and held July 25 - 28, 2006 at the University of Chester in the United Kingdom. Chemical Signals in Vertebrates 11 contains the latest research on chemical communication relevant to vertebrates, particularly focusing on new research since the last meeting in 2003. Topics covered include chemical ecology, biochemistry, behavior and neurobiology of both the main olfactory and vomeronasal systems of vertebrates, from amphibia to mammals including humans. A broad range of taxonomic groups and topics are discussed, including sections on new directions in semiochemistry, olfactory response and function, recognition within species, sexual communication, maternal-offspring communication, communication between species, and applications for zoo animal enrichment and pest control. The volume is dedicated to the memory of Dr. Bets Rasmussen and includes a special tribute chapter on her ground-breaking research on elephant communication.
Chemical Signals in Vertebrates 10
This book also represents the tenth in a series of books on chemical communication, chemical ecology, olfactory and vomeronasal research in vertebrate species. The species covered in the chapters herein range from fish to mammals including humans. By taxonomic breakdown the mammals are the most represented in number of species and chapter contributions. However, the hosts of the meeting endeavored to have some representative contributions covering all of the major vertebrate taxa.
Carcinoma della cervice uterina : Eziopatogenesi e profilassi = Carcinoma of the uterine cervix : Aetiopathogenesis and prophylaxis
The volume offers a synthetic and updated picture of a complex topic that includes the multifactorial etiopathogenesis of cervical cancer, the characteristics of the virus, the dynamics of HPV infections, the histological lesions of the cervix leading to cervical cancer. and the characteristics of the various surgical treatments, the current strategies for early diagnosis through the use of molecular assays currently on the market, up to the trials of the two vaccines recently registered also in Italy.
Cancer in the Arab World
Over the past few decades, the Arab world has witnessed a swift evolution in healthcare provision. Nonetheless, Arab countries have considerable variability in economic capabilities, resource allocation, and intellectual talent that inevitably reflect on access to modern cancer care and prevention. This book is authored by experts from the Arab world who provide vital information on cancer statistics and risk factors, available clinical care pathways and infrastructure, and prevention programs in their individual countries. The chapters also address specific challenges in each country and insights into future directions to achieve optimal care with conventional and novel diagnostics and therapies to keep up with the era of precision medicine.
Breast cancer chemosensitivity
In Breast Cancer Chemosensitivity, a group of world leading experts review critical aspects of resistance to systemic therapy in breast cancer patients. Beginning with a clinical overview of the problem Breast Cancer Chemosensitivity moves on to focus on the latest findings of molecular mechanisms of drug resistance. These include in-depth discussions on multidrug resistance by P-glycoprotein and the multidrug resistance protein family, resistance to therapeutic agent-induced apoptosis, cell cycle deregulation, deregulation of DNA repair, loss of tumor suppressor genes, integrin-mediated adhesion, insulin-like growth factors, epidermal growth factor, and ErbB2 in modulating breast cancer response to systemic therapy, especially, certain chemotherapeutic agents. Breast Cancer Chemosensitivity provides an example of using novel approaches for chemosensitization of breast cancer cells that gives readers an idea about the future direction in breast cancer treatment.
Brain tumor pathology : Current diagnostic hotspots and pitfalls
Since Bailey and Cushing (1926), all brain tumor classifications have been called histogenetic. The nosographic position that the tumor types progressively acquired in the classification systems derived from the resemblance of tumor cells to those of the cytogenesis, modified whenever new information became available from different biological research fields and especially from molecular genetics. Classically, on the basis of the rough correspondence between the mature/immature aspect of tumor cells and the benign/malignant biological behavior of the tumors, the histological labels contained a prognostic significance. The supposed origin of the tumors was thus a factor for prognosis. Later on, with the concept of anaplasia (Cox, 1933; Kernohan et al., 1949) new criteria were introduced for establishing the malignancy grades of tumors. Immunohistochemistry and later molecular genetics further refined the prognostic diagnoses, substantially increasing the opportunities to recognize the cell origin of tumors, beside revealing the pathogenetic mechanisms. Prognoses became more accurate, as required by the greater and more targeted possibilities of therapy.
Biosaline Agriculture and High Salinity Tolerance
this book reviews the current state of knowledge in biosaline agriculture and high salinity tolerance in plants. It mainly focuses on the biotic approach to economically utilize the stress-prone areas by growing resistant plants.This volume comprises three sections: physiology and biochemistry, ecology, and molecular biology. Thus, a systematic approach has been adopted to uncover plant responses to various ecological factors at physiological and molecular levels.
