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Clinical applications of botulinum toxin

Botulinum toxin (BoNT) is a neurotoxin produced by the Gram-positive, rod-shaped, sporeforming anaerobic bacterium Clostridium botulinum. Although there are seven major serotypes of Botulinum Neurotoxin (BoNT/A-G), only type A and B are used clinically. For the purpose of this research paper, we will refer to this agent as BoNT. This research paper primarily serves to provide a historical review of the toxin, assess its mechanism of action, and highlight the most common clinical applications of BoNT therapy across multiple medical specialties in an organized, specialty-based manner, including their complications and recommended BoNT dosages.

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Clinical Anatomy for Oral Implantology

Designed with the practicing implantologist in mind, and it has been revitalized to have the utmost relevance to the clinical reality of oral implantology today. Impeccable full-page illustrations demonstrate a detailed view of each anatomical area, and clinical photos, radiographs, CBCT scans, and cadaver specimens provide a complete picture of what the clinician can expect to encounter.

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Claytons basic pharmacology for nurses

Helps you understand the principles of pharmacology and apply them to nursing practice. Known for its practical application of the nursing process to drugs and disorders, this book explains how to make informed decisions about drug therapy, educate patients, and administer medications. This edition adds new Next Generation NCLEX® (NGN)-style case studies and questions to prepare you for the critical thinking questions on the NGN exam. Concise and easy to use, this text teaches the basics of medication administration and drug actions.

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Chromosomal alterations : Methods, results and importance in human health

Cytogenetics is a very important research tool in basic and applied research. The uses of cytogenetics in human-population monitoring, in biological dosimetry in radiation accidents and in astronauts and as a predictive measure of cancer are topics discussed in this book. The book will help the reader to better understand cytogenetics and the intricacies of the methodology. The different methods of fluorescence in situ hybridization are discussed and the results achieved are presented. The book provides a comprehensive review of basic and applied aspects of cytogenetics and therefore will be of interest to all who are interested in chromosomes and their alterations by different types of mutagens, including chemical mutagens and ionizing and nonionizing radiation, with special reference to electromagnetic fields.

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Chirurgia addominale d’urgenza : il buon senso di Schein: Guida pratica per sopravvivere nella trincea delle urgenze chirurgiche = Schein's common sense : A practical guide to surviving the trenches of surgical emergencies

This handy, concise, agile text is to be considered a practical guide, essential for the management and treatment of abdominal emergencies. Written and coordinated by a master of world surgery, with great experience in the field of emergency abdominal surgery, the volume is truly, for the surgeon on duty, an essential and life-saving tool, to always keep at hand. How to deal with an abdominal urgency (without wasting time and groping in the dark)? What checks are necessary? Which ones can be avoided? What surgical approach should be undertaken? In a clear, simple and punctual way, any doubts are addressed and clarified here.

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Chemotherapy and pharmacology for leukemia in pregnancy : Guidelines and strategies for best practices

The book addresses a broad range of subjects, including: pregnancy and its characteristics; staging, pathology, morbidity and what to expect in each type of leukemia; chemotherapy for leukemia in pregnant women with complete trials; dose adjustment of chemotherapy for leukemia in pregnancy based on serum dosages; and pharmacokinetics and pharmacodynamics for this unique group of patients. In turn, subsequent chapters focus on protecting the fetus and neonatal management regarding chemotherapy for leukemia in pregnancy, including the treatment and risks for the fetus (for each type of leukemia), intrathecal therapy and its effects on the fetus; supportive drugs, antibiotics and antifungals for pregnant patients during chemotherapy, including intervention and dose adjustments; palliative care for women with leukemia in pregnancy; breastfeeding during treatment for leukemia; pharmacological aspects of supplements, vitamins and nutrition in pregnancy during leukemia treatment; and more.

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Carpal Tunnel Syndrome

This book is an instrument for deepening their knowledge of this condition and its management. It can be considered a moment for reflection on a condition that is erroneously considered simple to treat and easy to resolve. The surgical chapters compare various complications as well as various conservative and rehabilitative treatment options, thus underlining that this condition must not be underestimated. Incorrect treatment can have many negative ramifications: not only that the patient is dissatisfied but it can also lead to the hand’s functional loss and render the patient an invalid.

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Cardiac drug therapy

Cardiac Drug Therapy, 7th ed., addresses the pharmacology and therapeutic application of drugs used to treat heart diseases and hypertension. Additions and updates to the sixth edition include six new chapters on current controversies in cardiac drug therapy such as the beta blocker issue many cardiologists are presently grappling with. The book provides practical advice on how to manage cardiac diseases and addresses the choice of one particular cardiac agent vs. another. In addition to providing core knowledge in cardiovascular therapeutics, the text assists in resolving some of the issues surrounding cardiac drugs. Cardiac Drug Therapy provides practical information including properties, dosage, side effects, potential salutary benefits, and drawbacks on virtually all commercially available cardiac drugs.

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Cancer in the Spine : Comprehensive Care

In Cancer in the Spine: Comprehensive Care, distinguished physicians and researchers from prestigious cancer centers around the world critically examine current trends and innovations in spinal cancer management. Detailing both the fundamental principles of diagnosis and treatment planning, and the cutting-edge techniques of tumor treatment, these experts bring together in one volume a guide to coordinated management of all aspects of cancer in the spine.

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Cancer Chemoprevention ; Vol.2 : Strategies for Cancer Chemoprevention

In Cancer Chemoprevention, Volume 2: Strategies for Cancer Chemoprevention, leading chemopreventives investigators comprehensively describe the exciting methodologies that are accelerating progress in the chemoprevention field and review the state of clinical development of preventive agents in the major human cancer target organs. The authors provide sound guidelines for cancer chemopreventive drug development, detailing general strategies and methods for drug discovery, preclinical efficacy, characterization of precancers, safety evaluation of clinical cohorts, and clinical trial design.

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Cálculo científico con MATLAB y Octave = Scientific computing with MATLAB and Octave

This textbook is an introduction to Scientific Calculus, illustrating various numerical methods for the computer solution of certain classes of mathematical problems. The authors show how to compute the zeros or integrals of continuous functions, solve linear systems, approximate functions by polynomials, and construct precise approximations for the solution of differential equations. To make the presentation concrete and attractive, the MATLAB programming environment has been adopted as a faithful companion.

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Buccal patches of salbutamol

The Potential of alternative routes of application compared to the traditional oral route is constantly growing. Especially in transmucosal applications for the oral cavity, the oral mucosa's accessibility, excellent blood supply, by-pass of hepatic first pass metabolism, rapid repair and permeability profile make it an attractive site for local and systemic drug delivery. Technology advance in mucoadhesive, sustained drug release, permeability enhancers and drug deliver vectors are increasing the efficient delivery of drug to treat oral and systemic disease...

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Brown and Mulholland’s drug calculations

A realistic practice problems and unique "proof" step in the answer key that allows you to double-check your answers to avoid medication errors. This edition continues to promote critical thinking, clinical judgment, and patient safety with respect to accurate drug dosages. Helpful worksheets, assessment tests, and Clinical Alerts call attention to situations in actual practice that have resulted in drug errors — giving you extensive hands-on practice for the Next Generation NCLEX® and beyond.

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Brain and Human Body Modeling 2020 : Computational Human Models Presented at EMBC 2019 and the BRAIN Initiative® 2019 Meeting

This book describes modern applications of computational human modeling in an effort to advance neurology, cancer treatment, and radio-frequency studies including regulatory, safety, and wireless communication fields.

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Brain and Human Body Modeling : Computational Human Modeling at EMBC 2018

This book describes modern applications of computational human modeling with specific emphasis in the areas of neurology and neuroelectromagnetics, depression and cancer treatments, radio-frequency studies and wireless communications. Special consideration is also given to the use of human modeling to the computational assessment of relevant regulatory and safety requirements. Readers working on applications that may expose human subjects to electromagnetic radiation will benefit from this book’s coverage of the latest developments in computational modelling and human phantom development to assess a given technology’s safety and efficacy in a timely manner.

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Botox side effect and natural alternatives

Botox is a drug made from a toxin produced by the bacterium Clostridium botulinum. It's the same toxin that causes a life-threatening type of food poisoning called botulism. Doctors use it in small doses to treat health problems. Botox injections work by weakening or paralyzing certain muscles or by blocking certain nerves. The effects last about three to twelve months, depending on what you are treating...

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Biopharmaceutics applications in drug development

This book introduces fundamental concepts, methods, and advances in the areas of dissolution, absorption, and permeability and their key applications in dosage form performance. Case studies are used to discuss the applications of biopharmaceutic strategies in the development of successful drugs, with a specific focus on the applications of biopharmaceutic strategies in the development of successful drugs. The book presents an integrated view in linking pharmaceutic to the biological consequences of drug products and leverages those for decision making in drug development.

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Biomaterials and bionanotechnology ; 1st ed.

Examines the current state of the field within pharmaceutical sciences and concisely explains the history of biomaterials including key developments. Written by experts in the field, this volume within the Advances in Pharmaceutical Product Development and Research series deepens understanding of biomaterials and bionanotechnology within drug discovery and drug development. Each chapter delves into a particular aspect of this fast-moving field to cover the fundamental principles, advanced methodologies and technologies employed by pharmaceutical scientists, researchers and pharmaceutical industries to transform a drug candidate or new chemical entity into a final administrable dosage form, with particular focus on biomaterials and bionanomaterials. This book provides a comprehensive examination suitable for researchers working in the pharmaceutical, cosmetics, biotechnology, food and related industries as well as advanced students in these fields.

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Biliary Lithiasis : Basic Science, Current Diagnosis and Management

The book provides an overview on biliary lithiasis and all its clinical pictures, twenty years after the first laparoscopic cholecystectomy. The gallbladder, the main bile duct and intra-hepatic stones, in their uncomplicated and complicated forms are illustrated.

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Aulton's pharmaceutics : The design and manufacture of medicines

A comprehensive textbook covering the design of dosage forms and all aspects of drug delivery systems. Pharmaceutics in its broadest sense is the 'art of the apothecary' or, in simple terms, pharmaceutical preparations. It remains a diverse subject in the pharmacy curriculum, encompassing design of drugs, their manufacture and the elimination of micro-organisms from the products.

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