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Advanced Peripheral Nerve Surgery and Minimal Invasive Spinal Surgery
A summary of the most recent and effective techniques for treating difficult functional problems and painful situations using minimally invasive spinal surgery techniques. Including an up-to-date review of the physiopathology of the diseases.
Adipose Tissue and Adipokines in Health and Disease
The aim of Adipose Tissue and Adipokines in Health and Disease is to provide comprehensive information regarding adipose tissue, its physiological functions and its role in disease. This volume contains a collection of information spanning the entire range of adipose tissue studies, from basic anatomical and physiological research to epidemiology and clinical aspects, in one place. This book is indispensable for basic researchers and clinicians interested in the fields of obesity, metabolic diseases, inflammation and immunity, and specialists in each of the pathologies associated with obesity.
Adhesion Molecules : Function and Inhibition
Inflammatory cell recruitment requires the concerted action of at least five major sets of adhesion molecules: integrins, immunoglobulin-like molecules, selectins, carbohydrate structures serving as selectin ligands, and certain ectoenzymes. This volume gives a comprehensive overview on the most relevant leukocyte and endothelial adhesion molecules. The chapters are written by leaders in the field and focus on the biology, structure, function, and regulation of adhesion molecules. Currently approved adhesion molecule-based therapies are reviewed and an outlook for future approaches is also provided. The book is of interest to clinicians and scientists from immunology, physiology, cancer research, rheumatology, allergology, infectious diseases, gastroenterology, pulmonology and cardiology.
Addition Reactions with Unsaturated Hydrocarbons
Addition Reactions with Unsaturated Hydrocarbons presents an up-to-date overview of modern methods that utilize reactions of unsaturated hydrocarbons as building blocks of organic synthesis, covering the conceptual and practical knowledge required for designing atom-efficient reactions to synthesize functionalized molecules. This authoritative volume discusses homo-dimerization and cross-dimerization of alkynes and/or alkenes, synthesis of carbonyl compounds from the hydration of alkynes, cycloadditions of alkynes and alkenes for the synthesis of carbocycles and heterocycles.
Acute Promyelocytic Leukemia : Molecular Genetics, Mouse Models and Targeted Therapy
Over the past 10 years, work on acute promyelocytic leukemia (APL) has become the paradigm of translational research that began with the discovery of a recurrent chromosomal translocation, followed by the identification of the genes and proteins involved, finding their molecular functions in transcriptional control, establishing mouse models and culminating in the development of targeted therapy.
Active Processes and Otoacoustic Emissions in Hearing
Sounds that are actually produced by healthy ears allow researchers and clinicians to study hearing and cochlear function noninvasively in both animals and humans. Active Processes and Otoacoustic Emissions in Hearing presents the first serious review of the biological basis of these otoacoustic emissions. Active processes, such as those in hair cells that produce emissions, represent a burgeoning and important area of sensory research. By providing a basis for understanding how and why otoacoustic emissions testing works through a basic understanding of general hearing processes, this volume will also interest clinicians, particularly otolaryngologists and audiologists.
Abord clinique en urologie = Clinical approach in urology
Seduced by the idea of commenting on the clinical experience they have acquired during their career, the authors have deliberately approached their specialty by describing the symptoms that give the chapters their titles. They nevertheless described the differential diagnoses, the diseases involved and the treatments. After a chapter devoted to the examination of the patient, including the detours of the interrogation, back pain or scrotal pain are analyzed. The authors then turned to voiding disorders and their causes. The peculiarities of hematuria, depending on their level of origin, are described and commented on. The semiology of tumor masses is carefully detailed and, conversely, the problem of prostate cancer screening by PSA is dealt with in a separate chapter. Erectile dysfunction and penile diseases are the last chapters. In the line of the “Clinical approach” collection, this manual is easy to consult thanks to a detailed index, easy to understand because it is written in clear language and, moreover, well illustrated (21 diagrams and 2 tables). In this little book, the authors have approached urology from a perspective close to how patients feel.
Abl Family Kinases in Development and Disease
Abl Family Kinases in Development and Disease provides an overview of the functions of Abl family kinases in Development and Disease. This new title discusses the biochemical, genetic, and cell biological data that elucidate the cellular roles for these kinases in these processes.
A Reappraisal of the Ascending Systems in Man, with Emphasis on the Medial Lemniscus
Based on material assembled by Dr Jaap HR Schoen who was one of the few neuroanatomists to apply the Nauta method to human material. Gaining insight in the consequences of longitudinal damage to the human spinal cord is necessary before reimplantation of the avulsed rootlets or an autologous transplant can be performed in man.
2D Functional Nanomaterials : Synthesis, Characterization, and Applications
In 2D Functional Nanomaterials: Synthesis, Characterization, and Applications, Dr. Ganesh S. Kamble presents an authoritative overview of the most recent progress in the rational design and synthesis of 2D nanomaterials and their applications in semiconducting catalysts, biosensors, electrolysis, batteries, and solar cells. This interdisciplinary volume is a valuable resource for materials scientists, electrical engineers, nanoscientists, and solid-state physicists looking for up-to-date information on 2D heterojunction nanomaterials.
25 Years of P53 Research
Communication, awareness and access to information: Given the complexity of the field and the fact that data pertaining to each particular aspects of p53 biology or deregulation are scattered in many different publications, it is extremely difficult to access the full scale of relevant information of any specific p53-related topic. This book may help in this task by putting into perspective both general considerations on the p53 pathway and more specific information on various aspects of p53. In the longer term, however, open access to p53 complexity will require the development of knowledge bases accessible through the web and using simple navigation tools to guide users towards the specific information they need. Several efforts are currently being developed in that direction. They need to be strenghtened and better integrated within the rapidly growing galaxy of web-based information sources on molecular and individual variations in cancer. 2. Reference functional assays and structural analysis: Given the huge diversity of cellular and animal models for wild-type or mutant p53 functions, it will be important to set up standard, universally accepted assays to measure critical p53 protein functions.
Judges and Adjudication in Constitutional Democracies : A View from Legal Realism
Offers contributions to a philosophical and realistic approach to the place of adjudication in contemporary constitutional democracies. Bringing together scholars from different legal and philosophical backgrounds, purports to cast light on the role(s) of judges and the function of judicial interpretation inside of constitutional states, from the standpoint of legal realism as a revisited and sophisticated jurisprudential outlook. In so doing, also copes with a few major jurisprudential issues, like, e.g., determining the ideas that make up the core of legal realism, exploring the relation between legal realism and legal positivism, identifying the boundaries of judicial interpretation as they appear from a realist standpoint, as well as considering some skeptical outlooks on the very claims of contemporary legal realism.
Managing Humans : Biting and Humorous Tales of a Software Engineering Manager
Managing Humans is a selection of the best essays from Michael Lopp's web site, Rands in Repose. Drawing on Lopp's management experiences at Apple, Netscape, Symantec, and Borland, this book is full of stories based on companies in the Silicon Valley where people have been known to yell at each other. It is a place full of dysfunctional bright people who are in an incredible hurry to find the next big thing so they can strike it rich and then do it all over again. Among these people are managers, a strange breed of people who through a mystical organizational ritual have been given power over your future and your bank account.
Logics of Specification Languages
Dedicated chapters address : the use of ASM (Abstract State Machines) in the classroom; the Event-B modelling method; a methodological guide to CafeOBJ logic; CASL, the Common Algebraic Specification Language; the Duration Calculus; the logic of the RAISE specification language (RSL); the specification language TLA+; the typed logic of partial functions and the Vienna Development Method (VDM); and Z logic and its applications. Each chapter is self-contained, with references, and symbol and concept indexes. Finally, in a unique feature, the book closes with short commentaries on the specification languages written by researchers closely associated with their original development.
Linear Systems, Signal Processing and Hypercomplex Analysis ; Chapman University, November 2017
includes contributions originating from a conference held at Chapman University during November 14-19, 2017. It presents original research by experts in signal processing, linear systems, operator theory, complex and hypercomplex analysis and related topics.
Linear Genetic Programming
Linear Genetic Programming examines the evolution of imperative computer programs written as linear sequences of instructions. In contrast to functional expressions or syntax trees used in traditional Genetic Programming (GP), Linear Genetic Programming (LGP) employs a linear program structure as genetic material whose primary characteristics are exploited to achieve acceleration of both execution time and evolutionary progress.
Liapunov Functions and Stability in Control Theory
Presents a modern and self-contained treatment of the Liapunov method for stability analysis, in the framework of mathematical nonlinear control theory. A Particular focus is on the problem of the existence of Liapunov functions (converse Liapunov theorems) and their regularity, whose interest is especially motivated by applications to automatic control.
Laser additive manufacturing: design, materials, processes and applications
Laser-based additive manufacturing (LAM) is a revolutionary advanced digital manufacturing technology developed in recent decades, which is also a key strategic technology for technological innovation and industrial sustainability. This technology unlocks the design and constraints of traditional manufacturing and meets the needs of complex geometry fabrication and high-performance part fabrication. A deeper understanding of the design, materials, processes, structures, properties and applications is desired to produce novel functional devices, as well as defect-free structurally sound and reliable LAM parts.The topics in this Special Issue reprint include macro- and micro-scale additive manufacturing with lasers, such as structure/material design, fabrication, modeling and simulation, in situ characterization of additive manufacturing processes and ex situ materials characterization and performance, with an overview that covers various applications in aerospace, biomedicine, optics and energy.
Knowledge Processing with Interval and Soft Computing
In particular, these chapters cover computing techniques for interval linear systems of equations, interval matrix singular-value decomposition, interval function approximation, and decision making with statistical and graph-based data processing. To enable these applications, the book presents a standards-based object-oriented interval computing environment in C++.
Kernel Methods for Machine Learning with Math and Python: 100 Exercises for Building Logic
Addresses the fundamentals of kernel methods for machine learning by considering relevant math problems and building Python programs. The book’s main features are as follows: Includes 100 exercises, which have been carefully selected and refined. As their solutions are provided in the main text, readers can solve all of the exercises by reading the book. / The mathematical premises of kernels are proven and the correct conclusions are provided, helping readers to understand the nature of kernels. / Source programs and running examples are presented to help readers acquire a deeper understanding of the mathematics used. / Once readers have a basic understanding of the functional analysis topics covered in Chapter 2, the applications are discussed in the subsequent chapters. Here, no prior knowledge of mathematics is assumed. / Considers both the kernel for reproducing kernel Hilbert space (RKHS) and the kernel for the Gaussian process; a clear distinction is made between the two.
