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Alzheimer's disease : Peptide vaccine and immunotherapy
Peptide vaccines and immunotherapies against aggregating proteins involved in the pathogenesis and progression of Alzheimer's disease (AD) the ẞ-amyloid peptide (Aẞ) and tau are promising therapeutic avenues against AD. Two decades of effort has led to the controversial United States Food and Drug Administration (FDA) approval of the monoclonal antibody Aducamumab (Aduhelm), which has subsequentially sparked the revival and expedited review of promising monoclonal antibody immunotherapies that target Aẞ.
Alzheimer's Disease
Alzheimer is a disease which has not a cure yet, and about 10% of the population worldwide will suffer from it. However younger people may also develop this disease mainly at 45 years old mainly women who has double the rate of incidence since 1 if five women will certainly develop it. Therefore the goal of our research is to study first of all the history of such popular disease and its risk factors and current therapies or iagnostic tools and more important we will introduce a test which was discovered few months ago to predict the risk of developing Alzheimer few decades before it occurs and we will apply it in our laboratories in Syria as well. Beside this preventive test we will add also a very important diet to follow up by people who has a family history.
Alternative medicine and it's uses in the treatment of kidney disease
The aim of this article was to review some of the new and commonly and alternative medicine in the treatment of kidney used medicinal plants , pharmacological activity, and research study of disease, kidney stones medicinal plants. Renal stones are a common problem worldwide with rden substantial morbidities and economic costs. The high economic bu associated with kidney stones is linked mainly with healthcare costs. In vitro and in vivo studies on alternative treatment of kidney stones have been searched by using words such as phytotherapy of kidney stones,. lithotriptic activity of plantss, and medicinal plants used in kidney stone Medicinal plants may be useful in treatment of kidney stones.
Alla ricerca della via più breve : Un'avventura matematica = Finding the shortest way : A mathematical adventure
Il libro narra la vicenda di Rut, quindicenne, trasferitasi da poco in Germania con la famiglia, al seguito del padre che lavora per un’azienda internazionale produttrice di Software. Sarà proprio il padre a regalare a Rut un computer nuovo, mentre a scuola attraversa un periodo di crisi.E’ l’inizio di un’avventura. Nel computer è installato Vim: un programma che ascolta, capisce e risponde alle domande che la ragazza, inizialmente incredula, fa. Raccontata da Vim, la matematica prende una forma completamente nuova, sorprendente e affascinante.
Algèbre, Chapitres 1 à 3 = Algebra, Chapters 1 to 3
To do algebra is essentially to calculate, that is to say to perform, on elements of a set, (<algebraic operations n, the best-known example of which is provided by the (<four rules)) of elementary arithmetic. This is not the place to retrace the slow process of progressive abstraction by which the notion of algebraic operation, initially restricted to natural integers and to measurable quantities, gradually widened its field, as it grew. at the same time generalized the notion of ((number O, until, going beyond the latter, it came to apply to elements which no longer had any character ((numeric)>, for example to permutations of a - seems (see Historical Note in chap. 1).
Algèbre, Chapitre 9 = Algebra, Chapter 9
Sesquilinear and quadratic forms : The Mathematics Elements of Nicolas BOURBAKI aim to provide a rigorous, systematic presentation without prerequisites of mathematics from their foundations. This ninth chapter of the Book of Algebra, the second Book of the treatise, is devoted to quadratic, symplectic or Hermitian forms and to associated groups.
Algèbre, Chapitre 4 à 7 = Algebra, Chapter 4 to 7
The Mathematics Elements of Nicolas BOURBAKI aim to provide a rigorous, systematic presentation without prerequisites of mathematics from their foundations. Deals in particular with extensions of fields and Galois theory. It includes the chaptires: 4. Polynomials and rational fractions; 5. Commutative bodies 6. Orderly groups and bodies; 7. Modules on the main rings
Algèbre commutative, Chapitre 10 = Commutative Algebra, Chapter 10
Depth, Regularity, Duality The Mathematics Elements of Nicolas BOURBAKI aim to provide a rigorous, systematic presentation without prerequisites of mathematics from their foundations. This volume of the Book of Commutative Algebra, Book 7 of the treatise, is a continuation of the earlier chapters. It introduces in particular the notions of depth and smoothness, fundamental in algebraic geometry. It ends with the introduction of the dualizing modules and the Grothendieck duality.
Algèbre commutative : Chapitres 8 et 9 = Commutative algebra : Chapters 8 and 9
The Mathematics Elements of Nicolas BOURBAKI aim to provide a rigorous, systematic presentation without prerequisites of mathematics from their foundations.
Algèbre commutative : Chapitres 5 à 7 = Commutative algebra : Chapters 5 to 7
The Mathematics Elements of Nicolas BOURBAKI aim to provide a rigorous, systematic presentation without prerequisites of mathematics from their foundations.This second volume of the Book of Commutative Algebra, Seventh Book of the treatise, introduces two fundamental notions in commutative algebra, that of algebraic integer and that of valuation, which have many applications in number theory and algebraic geometry.
Algèbre commutative : Chapitres 1à 4 = = Commutative algebra : Chapters 1 to 4
Nicolas BOURBAKI's Elements of Mathematics aim to provide a rigorous, systematic presentation without prerequisites of mathematics from their foundations. This first volume of the Book of Commutative Algebra, the seventh Book of the treatise, is devoted to the fundamental concepts of commutative algebra. It includes the chapters, Flat modules, Localization, Graduations, filtrations and topologies, First associated ideals and primary decomposition, It also contains historical notes. This volume is a reprint of the 1969 edition.
Algèbre : Chapitre 10 : Algèbre homologique = Algebra : Chapter 10 : Homological algebra
The Mathematics Elements of Nicolas BOURBAKI aim to provide a rigorous, systematic presentation without prerequisites of mathematics from their foundations. This tenth chapter of the Book of Algebra, the second Book of the treatise, lays the foundations of the homological calculus.
Algal Toxins : Nature, Occurrence, Effect and Detection
This volume contains the lectures and seminars given at the NATO Advanced Study Institute on “Sensor Systems for Biological Threads: The Algal Toxins Case”, held in Pisa, Italy in October, 2007. Algae can form heavy growths in ponds, lakes, reservoirs and sl- moving rivers throughout the world; algae can house toxins which are - ually released into water when the cells rupture or die. Hundreds of toxins have been identified so far. Detection methods, including rapid screening, have been developed to help us learning more about them, especially to find out which toxins are a real threat for people and what conditions encourage their production and accumulation. Early detection of algal toxins is an - portant aspect for public safety and natural environment, and significant efforts are underway to develop effective and reliable tools that can be used for this purpose.
Air-Ice-Ocean Interaction : Turbulent Ocean Boundary Layer Exchange Processes
At a time when the polar regions are undergoing rapid and unprecedented change, understanding exchanges of momentum, heat and salt at the ice-ocean interface is critical for realistically predicting the future state of sea ice. By offering a measurement platform largely unaffected by surface waves, drifting sea ice provides a unique laboratory for studying aspects of geophysical boundary layer flows that are extremely difficult to measure elsewhere. This book draws on both extensive observations and theoretical principles to develop a concise description of the impact of stress, rotation, and buoyancy on the turbulence scales that control exchanges between the atmosphere and underlying ocean when sea ice is present. Several interesting and unique observational data sets are used to illustrate different aspects of ice-ocean interaction ranging from the impact of salt on melting in the Greenland Sea marginal ice zone, to how nonlinearities in the equation of state for seawater affect mixing in the Weddell Sea.
AI in drug discovery
Constitutes the refereed proceedings of the First international workshop on ai in Drug Discovery, AIDD 2024, held as a part of the 33rd International Conference on Artificial Neural Networks, ICANN 2024, in Lugano, Switzerland, on September 19, 2024. These papers focus on various aspects of the rapidly evolving field of Artificial Intelligence (AI)-driven drug discovery in chemistry, including Big Data and advanced Machine Learning, eXplainable AI (XAI), Chemoinformatics, Use of deep learning to predict molecular properties, Modeling and prediction of chemical reaction data and Generative models.
Agriculture for Economic Development in Africa : Evidence from Ethiopia
This book explores the role of agriculture in long-term economic growth. With a particular focus on Ethiopia, the role of the state in igniting agricultural growth and in sustaining economic growth is highlighted as essential for low-income countries. Taking ideas from both economic history and development economics, the ability of Ethiopia and the rest of Africa to sustain recent rapid growth into something that can tackle the development agenda is discussed, alongside policy suggestions.
Agriculture and Climate Beyond 2015 : A New Perspective on Future Land Use Patterns
Interactions between agriculture, climate and patterns of land use are complex. Major changes in agriculture, and land use patterns are foreseen in the next couple of decades in response to shifts in climate, greenhouse gas management initiatives, population growth and other forces. The book explores key interactions between changes in agriculture, patterns of land use and efforts to reduce greenhouse emissions from agriculture. The volume is based on inter-disciplinary science and policy interactions, exploring the way land use may aid in addressing or be affected by the onset of climate change and alterations in food demand. Future forces shaping land use decisions are examined, and its sensitivity to climate change is highlighted. Patterns of land use and the agricultural role in climate change mitigation are explored. Also, policy and social responses to the new perspectives on future land use patterns are identified. The perspective of the book is beyond the year 2015.
Agent-oriented information systems II ; 6th International bi-conference workshop, AOIS 2004, Riga, Latvia, June 8, 2004 and New York, NY, USA, July 20, 2004, revised selected papers
Information systems have become the backbone of all kinds of organizations - day. In almost every sector – manufacturing, education, health care, government and businesses large and small – information systems are relied upon for - eryday work, communication, information gathering and decision-making. Yet, the in?exibilities in current technologies and methods have also resulted in poor performance, incompatibilities and obstacles to change. As many organizations are reinventing themselves to meet the challenges of global competition and e-commerce, there is increasing pressure to develop and deploy new technologies that are ?exible, robust and responsive to rapid and unexpected change. Agent concepts hold great promise for responding to the new realities of - formation systems. They o?er higher-level abstractions and mechanisms which address issues such as knowledge representation and reasoning, communication, coordination, cooperation among heterogeneous and autonomous parties, p- ception, commitments, goals, beliefs, intentions, etc., all of which need conc- tual modelling. On the one hand, the concrete implementation of these concepts can lead to advanced functionalities.
Agent-Based Simulation : From Modeling Methodologies to Real-World Applications; Post Proceedings of the Third International Workshop on Agent-Based Approaches in Economic and Social Complex Systems 2004
Agent-based modeling/simulation is an emerging field that uses bottom-up and experimental analysis in the social sciences. Selected research from that presented at the Third International Workshop on Agent-Based Approaches in Economic and Social Complex Systems 2004, held in May 2004 in Kyoto, Japan, is included in this book. The aim of the workshop was to employ the bottom-up approach to social and economic problems by modeling, simulation, and analysis using a software agent. This research area is an emerging interdisciplinary field among the social sciences and computer science, attracting broad attention because it introduces a simulation-based experimental approach to problems that are becoming increasingly complex in an era of globalization and innovation in information technology. The state-of-the-art research and findings presented in this book will be indispensable tools for anyone involved in this rapidly growing discipline.
Affordable housing for smart villages
Initiates a fresh discussion of affordability in rural housing set in the context of the rapidly shifting balance between rural and urban populations. It conceptualises affordability in rural housing along a spectrum that is interlaced with cultural and social values integral to rural livelihoods at both personal and community level. Developed around four intersecting themes: explaining houses and housing in rural settings; exploring affordability in the context of aspirations and vulnerability; rural development agendas involving housing and communities; and construction for resilience in rural communities, the book provides an overview of some of the little understood and sometimes counter-intuitive best practices on rural affordability and affordable housing that have emerged in developing economies over the last thirty years.
