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Microarray technology and Its applications
The genomics revolution would not have been possible without the 'parallelisation' offered by microarray technology. This technological - and commercial - success has been since emulated by other applications areas, with a tremendous amplification of innovation. This book describes the fundamentals and latest developments in microarray technology, as well as its future directions. It presents detailed overviews of the different techniques of fabricating microarrays, of the chemistries and preparative steps involved, of the different types of microarrays, and of the instrumentation and optical issues involved.
Metodi Matematici della Fisica = Mathematical Methods of Physics
This text draws its origin from my old notes, prepared for the course of Mathematical Methods of Physics and gradually arranged, refined and updated over the course of many years of teaching. The aim has always been to provide as simple and direct a presentation as possible of the mathematical methods relevant to Physics: Fourier series, Hilbert spaces, linear operators, functions of complex variables, Fourier and Laplace transforms, distributions. In addition to these basic topics, a brief introduction to the first notions of group theory, Lie algebras and symmetries in view of their applications to Physics is presented in the Appendix.
Methods to study litter decomposition : A practical guide
Decomposition of organic matter is a major ecosystem process involving an array of different organisms, including bacteria, fungi and invertebrates. The main objective of this book is to provide students and laboratory instructors at universities and professional ecologists with a broad range of established methods to study plant litter decomposition. Detailed protocols for direct use in the field or laboratory are presented in an easy to follow step-by-step format. A short introduction to each protocol reviews the ecological significance and principles of the technique and points to key references. Although most methods are described for freshwater ecosystems, many will work equally well in the presented or slightly modified form for studies in marine and terrestrial environments.
Methods in Nonlinear Analysis
Nonlinear analysis has developed rapidly in the last three decades. Theories, techniques and results in many different branches of mathematics have been combined in solving nonlinear problems. This book collects and reorganizes up-to-date materials scattered throughout the literature from the methodology point of view, and presents them in a systematic way. It contains the basic theories and methods with many interesting problems in partial and ordinary differential equations, differential geometry and mathematical physics as applications.There are five chapters that cover linearization, fixed-point theorems based on compactness and convexity, topological degree theory, minimization and topological variational methods. Each chapter combines abstract, classical and applied analysis. Particular topics included are bifurcation, perturbation, gluing technique, transversality, Nash–Moser technique, Ky Fan's inequality and Nash equilibrium in game theory, setvalued mappings and differential equations with discontinuous nonlinear terms, multiple solutions in partial differential equations, direct method, quasiconvexity and relaxation, Young measure, compensation compactness method and Hardy space, concentration compactness and best constants, Ekeland variational principle, infinite-dimensional Morse theory, minimax method, index theory with group action, and Conley index theory.
Methods for measuring greenhouse Gas balances and evaluating mitigation options in smallholder agriculture
This book provides standards and guidelines for quantifying greenhouse gas emissions and removals in smallholder agricultural systems and comparing options for climate change mitigation based on emission reductions and livelihood trade-offs. Globally, agriculture is directly responsible for about 11% of annual greenhouse gas (GHG) emissions and induces an additional 17% through land use change, mostly in developing countries. Farms in the developing countries of sub-Saharan Africa and Asia are predominately managed by smallholders, with 80% of land holdings smaller than ten hectares. However, little to no information exists on greenhouse gas emissions and mitigation potentials in smallholder agriculture.
Metakaolin and Fly Ash as Mineral Admixtures for Concrete
Deals with modern theoretical concepts related to the impact of fly ash and metakaolin admixtures on structure formation processes of concrete. Results of the effect of fly ash, metakaolin and their composition on properties of self-compacting and self-leveling concrete are presented. Based on mathematical models, obtained using mathematical experiments planning methodology, the impact of the main factors and their combination on workability, strength and other properties that determine efficiency and durability of concrete are analyzed. Using calculated dependencies, a methodology for designing optimal compositions of concrete containing active mineral admixtures and superplasticizers is proposed. Features of industrial production of concrete for the proposed compositions are discussed. The book is intended for specialists working in the production of concrete and reinforced concrete products and elements. It can also be used by construction engineers to design compositions of cost-effective self-compacting and self-leveling concrete as well as to determine the rational direction of using technogenic raw materials like ash and metakaolin.
Metabolomics : The frontier of systems biology
Metabolism is the sum of the chemical reactions in cells that produce life-sustaining chemical energy and metabolites. In the post-genome era, metabolism has taken on new significance for biological scientists: metabolites are the chemical basis of phenotypes that are final expressions of genomic information. This book covers research on metabolomics, ranging from the development of specialized chemical analytical techniques to the construction of databases and methods for metabolic simulation. The authors have been directly involved in the development of all the subject areas, including capillary electrophoresis, liquid chromatography, mass spectrometry, metabolic databases, and metabolic simulation. Breakthrough achievements and the future of metabolome studies are described, making this book a valuable source for researchers in metabolomics in diverse fields, such as plant, animal, cellular, microbial, pharmaceutical, medical, and genetic sciences.
Membrane Computing ; Vol. 3850 ; 6th International Workshop, WMC 2005, Vienna, Austria, July 18-21, 2005, Revised Selected and Invited Papers
The papers in this volume cover all the main directions of research in membrane computing, ranging from theoretical topics in mathematics and computer science, to application issues, especially in biology. More specifically, these papers present research on topics such as: computational power and complexity classes, new types of P systems, relationships to Petri nets, quantum computing, and brane calculi, determinism vs. nondeterminism, hierarchies, the size of small families, algebraic approaches, and designing polynomial solutions to NP-complete problems through the use of membrane systems. Like the previous workshops,
Medicinal plants : Bioprospecting and pharmacognosy
Touches on a diverse selection of topics related to medicinal plants. Chapters look at the use of medicinal plants in healthcare and disease management, such as to treat inflammation, anti-hyperglycemia, and obesity and as immunity boosters. The authors also address the conservation, maintenance, and sustainable utilization of medicinal plants along with postharvest management issues. Topics include consumption, supply chain, marketing, trade, and future directions of research. Some specific plants discussed include fennel, basil, clove, ginger, lavender, turmeric, ginsing, and asparagus in connection with their various therapeutic properties, including anti-rheumatic, anti-asthmatic, anti-diabetic, carminative, diuretic, fever-reducing, and hypotensive. Medicinal Plants: Bioprospecting and Pharmacognosy will prove informative for scientists and researchers in medicinal plants as well as for faculty and students, pharmaceutical researchers, and others.
Medical terminology : Learning through practice
Designed to direct your study of medical terminology by guiding you through an organizedapproach to step-by-step learning. Author Paula Bostwick has invested her time,research, and talents to help you succeed in learning medical terminology.
Medical Reprints: 3D ed.
3D printing or additive manufacturing is a novel method of manufacturing parts directly from a digital model by using layer by layer material build-up approaches. This discovery is predicted to have the greatest impact on the future industries. Additive manufacturing has numerous applications in different areas including healthcare. Applications encompass many medical fields such as dentistry, surgery, and medical devices as well as the pharmaceutical field. Due to transplant donor deficiencies, ‘bioprinting’ has been invented to print biocompatible organs. Adding ‘time’ as a 4th dimension, 4D printing uses ‘smart materials’ to initiate the ‘smart drugs’ era.
Mechanisms of mineralization of vertebrate skeletal and dental tissues
Presents a multi-disciplinary approach to understanding mechanisms regulating the formation of mineral in vertebrate skeletal and dental tissues. The focus of the book is directed toward the mineralization process, an evolutionarily conserved system in which cells synthesize a complex and unique extracellular matrix into which mineral is deposited. Regulatory control is viewed though lenses that emphasize the genetic, physical-chemical, biochemical, structural, cellular and extracellular aspects of the mineralization process as they relate to crystal nucleation, growth and maturation. Throughout the book, defects in regulation at the genetic and transcriptional levels are linked to the numerous clinical problems associated with the mineralization of bone, cartilage, tendon, tooth, and soft tissues.
Mechanics of Biological Tissue
The mechanics of biological tissues is a multidisciplinary and rapidly expanding area of research. This book highlights some important research directions that combine mechanical sciences with exciting new developments in biology. This collection of papers should be of interest to theoretical, computational and experimental researchers and doctoral students in the area of biomechanics and in related areas of engineering, biology and medicine.
MATLAB® Recipes for Earth Sciences
MATLAB® is used in a wide range of applications in geosciences, such as image processing in remote sensing, generation and processing of digital elevation models and the analysis of time series. This book introduces methods of data analysis in geosciences using MATLAB such as basic statistics for univariate, bivariate and multivariate datasets, jackknife and bootstrap resampling schemes, processing of digital elevation models, gridding and contouring, geostatistics and kriging, processing and georeferencing of satellite images, digitizing from the screen, linear and nonlinear time-series analysis and the application of linear time-invariant and adaptive filters. The revised and updated Second Edition includes new subchapters on windowed Blackman-Tukey, Lomb-Scargle and Wavelet powerspectral analysis, statistical analysis of point distributions and digital elevation models, and a full new chapter on the statistical analysis of directional data. The text includes a brief description of each method and numerous examples demonstrating how MATLAB can be used on data sets from earth sciences. All MATLAB recipes can be easily modified in order to analyse the reader's own data sets.
Mathematics for Life Science and Medicine
Dynamical systems theory in mathematical biology has attracted much attention from many scientific directions. The purpose of this volume is to present and discuss the many rich properties of the dynamical systems that appear in life science and medicine. The main topics include cancer treatment, dynamics of paroxysmal tachycardia, vector disease models, epidemic diseases and metapopulations, immune systems, pathogen competition and coexistence and the evolution of virulence and the rapid evolution of viruses within a host. Each chapter will serve to introduce students and scholars to the state-of-the-art in an exciting area, to present new results, and to inspire future contributions to mathematical modeling in life science and medicine.
Mathematics for Ecology and Environmental Sciences
Dynamical systems theory in mathematical biology has attracted much attention from many scientific directions. The purpose of this volume is to discuss the many rich and interesting properties of dynamical systems that appear in ecology and environmental sciences. The main topics include population dynamics with dispersal, nonlinear discrete population dynamics, structured population models, mathematical models in evolutionary ecology, stochastic spatial models in ecology, game dynamics and the chemostat model. Each chapter will serve to introduce students and scholars to the state-of-the-art in an exciting area, to present important new results, and to inspire future contributions to mathematical modeling in ecology and environmental sciences.
Mathematical Models of Granular Matter
Granular matter displays a variety of peculiarities that distinguish it from other appearances studied in condensed matter physics and renders its overall mathematical modelling somewhat arduous. Prominent directions in the modelling granular flows are analyzed from various points of view. Foundational issues, numerical schemes and experimental results are discussed. The volume furnishes a rather complete overview of the current research trends in the mechanics of granular matter. Various chapters introduce the reader to different points of view and related techniques. New models describing granular bodies as complex bodies are presented. Results on the analysis of the inelastic Boltzmann equations are collected in different chapters. Gallavotti-Cohen symmetry is also discussed.
Invited Lectures from the 13th International Congress on Mathematical Education
The book presents the Invited Lectures given at 13th International Congress on Mathematical Education (ICME-13). The papers present the work of prominent mathematics educators from all over the globe and give insight into the current discussion in mathematics education. The Invited Lectures cover a wide spectrum of topics, themes and issues and aim to give direction to future research towards educational improvement in the teaching and learning of mathematics education. This book is of particular interest to researchers, teachers and curriculum developers in mathematics education.
Investing in e-Health : What it Takes to Sustain Consumer Health Informatics
Investing in eHealth: What it Takes to Sustain Consumer Health Informatics examines the evolution of the IHCS and the significant changes in organizational culture and operational systems that may be required for successful and sustained implementation. This book culminates a set of general guidelines for any health care provider striving to successfully employ the model, and suggests directions for future research on the diffusion of IHCSs and related technologies. Investing in eHealth provides a principled approach to support health care managers, clinicians, and educators interested in complementing clinical services with interactive health communication systems (IHCSs).
Inventory and Supply Chain Management with Forecast Updates
Inventory and Supply Chain Management with Forecast Updates is concerned with the problems of inventory and supply chain decision making with information updating over time. The models considered include inventory decisions with multiple sources and delivery modes, supply-contract design and evaluation, contracts with exercise price, volume-flexible contracts allowing for spot-market purchase decisions, and competitive supply chains. Real problems are formulated into tractable mathematical models, which allow for an analysis of various approaches, and provide insights for better supply chain management. The book provides a unified treatment of these models, presents a critique of the existing results, and points out potential research directions. Attention is focused on solutions – that is, inventory decisions prior and subsequent to information updates and the impact of the quality of information on these decisions.
