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Artrite reumatoide e spondiloentesoartriti : Diagnostica per immagini e imaging follow-up = Rheumatoid Arthritis and Spondyloentesoarthritis : Follow-up imaging and imaging
Recent technological evolutions in diagnostic imaging have allowed him to grasp the anatomical and functional alterations that characterize the onset phase of degenerative and inflammatory arthropathies. In the context of the latter, in particular, imaging is not only fundamental in the diagnosis of the early stage of arthritis but also in defining their evolution and response to modern therapeutic treatment. The evaluation of a new imaging semeiology, which makes considerable use of the use of contrast medium in relation to both power Doppler and magnetic resonance imaging, has made it possible to narrow the gap between histology and imaging in rheumatological diagnostics.
Artificial intelligence in drug design
Looks at applications of artificial intelligence (AI), machine learning (ML), and deep learning (DL) in drug design. The chapters in this book describe how AI/ML/DL approaches can be applied to accelerate and revolutionize traditional drug design approaches such as: structure- and ligand-based, augmented and multi-objective de novo drug design, SAR and big data analysis, prediction of binding/activity, ADMET, pharmacokinetics and drug-target residence time, precision medicine and selection of favorable chemical synthetic routes. How broadly are these approaches applied and where do they maximally impact productivity today and potentially in the near future.
Antioxidants effects in health : The bright and the dark side ; 1st ed.
Examines the role that antioxidants play in a variety of health and disease situations. The book discusses antioxidants’ historical evolution, their oxidative stress, and contains a detailed approach of 1) endogenous antioxidants, including endogenous sources, mechanisms of action, beneficial and detrimental effects on health, in vitro evidence, animal studies and clinical studies; 2) synthetic antioxidants, including sources, chemistry, bioavailability, legal status, mechanisms of action, beneficial and detrimental effects on health, in vitro evidence, animal studies and clinical studies; and 3) natural antioxidants, including sources, chemistry, bioavailability, mechanisms of action, possible prooxidant activity; beneficial and detrimental effects on health, in vitro evidence, animal studies and clinical studies. Throughout the boo, the relationship of antioxidants with different beneficial and detrimental effects are examined, and the current controversies and future perspectives are addressed and explored. Antioxidants Effects in Health: The Bright and the Dark Side evaluates the current scientific evidence on antioxidant topics, focusing on endogenous antioxidants, naturally occurring antioxidants and synthetic antioxidants. It will be a helpful resource for pharmaceutical scientists, health professionals, those studying natural chemistry, phytochemistry, pharmacognosy, natural product synthesis, and experts in formulation of herbal and natural pharmaceuticals.
Anatomical Imaging : Towards a New Morphology
This book presents selected works of contemporary evolutionary morphologists and includes such topics as broad scale reconstructions of the brain and ear of dinosaurs, inference of locomotor habits from cancellous bone architecture in fossil primates, and a comparison of the independently evolved manipulating apparatuses in the lesser and giant pandas. Insight is provided into the application of modern noninvasive technologies, including digital imaging techniques and virtual 3D reconstruction, to the investigation of complex anatomical features and coherences. In combination with traditional methods, this allows for the formulation of improved hypotheses on coordinated function and evolution. The creation of virtual translucent specimens makes it possible to realize the age-old dream of the classical anatomists: looking through the skin into the inner organization of an organism. On full display here is the dramatic and promising impact that modern imaging techniques have on scientific progress in evolutionary morphology.
Anaesthesia, pain, intensive care and emergency medicine A.P.I.C.E. ; Proceedings of the 21st Postgraduate Course in Critical Medicine: Venice-Mestre, Italy - November 10-13, 2006
Developing sectors in the Intensive Care field – and in Critical Care Medicine in general – require specific levels of competence having a same common denominator: an in-depth knowledge of human pathophysiology. Although this volume presents plenty of topics in constant evolution, as witnessed by the collection of chapters compiled by several researchers, this edition includes, in particular, fields in which decision-making at the patient’s bedside prevails over theoretical argumentation. In other words, the first and foremost message this edition wants to provide is for the reader to focus his/her attention on evidence-based medicine.
AI in disease detection : Advancements and applications
Discusses the integration of artificial intelligence to revolutionize disease detection approaches, with case studies of AI in disease detection as well as insight into the opportunities and challenges of AI in healthcare as a whole. The book explores a wide range of individual AI components such as computer vision, natural language processing, and machine learning as well as the development and implementation of AI systems for efficient practices in data collection, model training, and clinical validation.
Agricultural Research Management
Agricultural research is one of the most widespread forms of organized research in the world, in both developed and developing countries. Management of agricultural research involves many decisions that have scientific, social and political consequences. Every country has established agricultural research priorities based on many complex factors that must be considered when decisions are made on the choice of research problems to be investigated. Resources must be divided among projects that often compete for the limited funding available that supports the total research enterprise.
Agricultural Biotechnology in China : Origins and Prospects
Building on a long tradition of agricultural advances, Chinese scientists have applied biotechnology techniques to develop hundreds of novel crop varieties suited to local farming conditions and challenges.Agricultural Biotechnology in China: Origins and Prospects is a comprehensive examination of how the origins of biotechnology research agendas, along with the effectiveness of the seed delivery system and biosafety oversight, help to explain current patterns of crop development and adoption in China. Based on firsthand insights from China’s laboratories and farms, Valerie Karplus and Dr. Xing Wang Deng explore the implications of China’s investment for the nation’s rural development, environmental footprint, as well as its global scientific and economic competitiveness.
Ageing : The Paradox of Life : Why We Age
For centuries people have been puzzled by the inevitability of human aging. For most of the second half of the twentieth century aging remained a mystery, or an unsolved biological problem. At the end of the 20th century a remarkable scientific discovery emerged. It was not a single discovery in the usual sense, because it was based on a series of important interconnected insights over quite a long period of time. These insights made it possible for the very first time to understand the biological reasons for aging in animals and man. It can already be said, however, that the many observations and insights that explain aging will not be accepted as established knowledge for a long time.
African Biodiversity : molecules, organisms, ecosystems
BIOTA is an interdisciplinary research project focusing on sustainable use and conservation of biodiversity in Africa (http://www.biote-africa.de). Session titles were Biogeography and Speciation Processes, Phylogenetic Patterns and Systematics, Diversity Declines and Conservation, and Applied Biodiversity Informatics
Adaptive dynamic programming for chemotherapy drug delivery
Focuses on the practical application of Adaptive Dynamic Programming (ADP) in chemotherapy drug delivery, taking into account clinical variables and real-time data. ADP's ability to adapt to changing conditions and make optimal decisions in complex and uncertain situations makes it a valuable tool in addressing pressing challenges in healthcare and other fields. As optimization technology evolves, we can expect to see even more sophisticated and powerful solutions emerge.
About Life : Concepts in Modern Biology
This book uses modern biological knowledge to tackle the question: "What distinguishes living organisms from the non-living world?" In the first few chapters, the authors draw on recent advances in cell and molecular biology to develop an account of the "living state" that applies to all organisms, but only to organisms. Subsequent chapters use this account to explore questions about evolution, the origin of life and the possibility of extraterrestrial life. Towards the end of the book the authors consider human evolution, intelligence and the extent to which our species can be regarded as biologically unique. About Life is written as far as possible in non-technical language; all scientific terms are explained straightforwardly when they are introduced. It is aimed at the general, non-specialist reader, but the novel approach that it takes to general issues in biology will also interest students of the life sciences.
A Legacy for Living Systems : Gregory Bateson as Precursor to Biosemiotics
This book represents a major attempt to revise this deficiency. Scholars from ecology, biochemistry, evolutionary biology, cognitive science, anthropology and philosophy discuss how Bateson's thinking might lead to a fruitful reframing of central problems in modern science. Most important perhaps, Bateson's bioanthropology is shown to play a key role in developing the set of ideas explored in the new field of biosemiotics. The idea that organismic life is indeed basically semiotic or communicative lies at the heart of the biosemiotic approach to the study of life.The only book of its kind, this volume provides a key resource for the quickly-growing substratum of scholars in the biosciences, philosophy and medicine who are seeking an elegant new approach to exploring highly complex systems.
A History of Limb Amputation
This book traces humanity’s long experience of natural amputations due to congenital absence, disease, frostbite, toxins, domestic and wild animal trauma, and for non-medical reasons related to punitive, ritual, and legal actions, ultimately leading to the development of elective surgical amputation. While the evolution of surgical techniques forms a major chapter in the book, many ancillary problems are addressed including the control of hemorrhage and infection, the approach to pain relief, the development of suitable instruments and equipment, and the invention of prostheses, all suitably illuminated with case histories and relevant illustrations. In addition, alternative procedures designed to avoid amputation, increasingly important in the last two centuries, are debated, and factors associated with self-amputation in extremis, not rare according to press reports, are also examined. A separate chapter considers the philosophy and interpretations of society, patients, and surgeons faced with amputation, particularly before anesthesia.
A History of Atmospheric CO2 and Its Effects on Plants, Animals, and Ecosystems
The authors address the future role of atmospheric CO2 and its likely effects on ecosystems. This book incorporates the advances of various earth science, environmental, and ecological fields into an overall account of global change and the changing dynamics of life on Earth.
3D printing of pharmaceutical and drug delivery devices progress from bench to bedside
Discover the latest, fast-developing technology to help move towards more cost-effective, small-batch, decentralized manufacturing of personalized systems . 3D printing has revolutionized manufacturing. Its precision and flexibility have enabled the large-scale production of materials and devices too complex for conventional industrial manufacturing. This has been particularly revolutionary in the field of pharmaceutical production, where 3D printing is being integrated into the manufacture of both drugs and drug delivery devices. It has never been more important for industry professionals to understand this form of production.
Magazines, Tourism, and Nation-Building in Mexico
This book discusses the relationship between periodicals, tourism, and nation-building in Mexico. It enquires into how magazines, a staple form of the promotional apparatus of tourism since its inception, articulated an imaginative geography of Mexico at a time when that industry became a critical means of economic recovery and political stability after the Revolution. Notwithstanding their vogue, popularity, reach, and close affiliations to commerce and state over several decades, magazines have not received any sustained critical attention in the scholarship on that period.
Artificial intelligence and legal analytics : new tools for law practice in the digital age
The field of artificial intelligence (AI) and the law is on the cusp of a revolution. This book - designed to explain computational processes to non-programmers - describes how text analytic programs will change the practice of law, specifically by connecting computational models of legal reasoning directly with legal text.
Managed Software Evolution
This open access book presents the outcomes of the “Design for Future – Managed Software Evolution” .The different lifecycles of software and hardware platforms lead to interoperability problems in such systems. Instead of separating the development, adaptation and evolution of software and its platforms, as well as aspects like operation, monitoring and maintenance, they should all be integrated into one overarching process. Accordingly, the book is split into three major parts, the first of which includes an introduction to the nature of software evolution, followed by an overview of the specific challenges and a general introduction to the case studies used in the project. The second part of the book consists of the main chapters on knowledge carrying software, and cover tacit knowledge in software evolution, continuous design decision support, model-based round-trip engineering for software product lines, performance analysis strategies, maintaining security in software evolution, learning from evolution for evolution, and formal verification of evolutionary changes. In turn, the last part of the book presents key findings and spin-offs. The individual chapters there describe various case studies, along with their benefits, deliverables and the respective lessons learned. An overview of future research topics rounds out the coverage.
Machine Learning in Computer Vision
The goal of this book is to address the use of several important machine learning techniques into computer vision applications. An innovative combination of computer vision and machine learning techniques has the promise of advancing the field of computer vision, which contributes to better understanding of complex real-world applications. The effective usage of machine learning technology in real-world computer vision problems requires understanding the domain of application, abstraction of a learning problem from a given computer vision task, and the selection of appropriate representations for the learnable (input) and learned (internal) entities of the system. In this book, we address all these important aspects from a new perspective: that the key element in the current computer revolution is the use of machine learning to capture the variations in visual appearance, rather than having the designer of the model accomplish this. As a bonus, models learned from large datasets are likely to be more robust and more realistic than the brittle all-design models.
