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Changing Land Use Patterns in the Coastal Zone : Managing Environmental Quality in Rapidly Developing Regions

Coastal ecosystems make up some of the most important, yet most endangered, regions in the world. The protection of the unique processes that take place in these ecosystems requires that partnerships be formed among ecologists, resource managers, and planners. Experienced in the challenges of coastal system analysis, the contributors to this book provide multidisciplinary guidance on the assessment and management of environmental impacts caused by development. Each chapter examines an issue important to these fragile ecosystems, first presenting a non-technical summary of the issue and a review of the current state of the knowledge, then following with data and a more detailed consideration of the topic.

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Cell Communication in Nervous and Immune System

At first glance, the nervous and immune systems appear very different. However, both systems have developed mechanisms for memory formation – though of quite different quality and significance for the organism. One striking example is that both systems form and communicate via synapses armed with similar sets of proteins. This collection of reviews, contributed by internationally recognized immunologists and molecular and cellular neurobiologists, puts side by side cellular communication devices and signaling mechanisms in the immune and nervous systems and discusses mechanisms of interaction between the two systems, the significance of which has only recently been fully appreciated.

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Care-Related Quality of Life in Old Age : Concepts, Models and Empirical Findings

Care-Related Quality of Life in Old Age explains the theory behind Care Keys, its methodology, empirical findings, and practical considerations in promoting effective, efficient elder care aimed at social and emotional well-being and including disabled and cognitively impaired patients.

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Cancer in adolescents and young adults

The chapters highlight the initial efforts of this Committee in addressing the scope of the problem of adolescent and young adult underrepresentation in clinical trials and offer evidence that such adiscrepancy may partially explain outcome differences.In addition, these chapters present information about biologic differences between specific cancer subtypes most common in younger children and those exhibited by the same cancers in adolescents and young adults, and offer plausible explanations for outcome differences as well as potential treatment strategies.

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Cancer et traitement: Domicile ou hôpital : Le choix du patient = Cancer and treatment : Home or hospital : The patient's choice

This book takes stock of the needs, expectations and challenges of caring for a cancer patient at home or in hospital. Indeed, if the number of cancer cases is increasing in Western countries, their management is evolving. The emphasis today is on a more humane announcement of the disease, less aggressive treatments and a better quality of life. Better informed patients often wish to be treated at home. As the survival time lengthens, hospital stays are reduced and chosen. Home care teams will soon be relying on the hospital more easily, thanks to specific communication methods and care networks. Here, all the stakeholders involved in the psycho-oncological approach to the patient discuss the choice of place and means of treatment for patients: from the general practitioner to the psychologist, from the oncologist to the mobile palliative care unit.

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Cancer du testicule = Testicular cancer

Testicular cancer has benefited from important therapeutic advances radically transforming its prognosis. Recent protocols have led to the development of treatments that maintain therapeutic efficacy while favoring quality of life and minimizing the sequelae (such as fertility disorders) in these often young men. This book discusses the various technical advances both in the field of diagnosis - with the contribution of modern imaging and anatomopathology - and therapy. The place of chemotherapy as well as that of surgery are largely detailed, thus placing the urologist at the heart of the multidisciplinary team taking care of these patients. Quality of life is also discussed by taking into account the impact of the treatment of these tumors on the fertility of these young patients.

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Breast MRI : Fundamentals and technical aspects

The text walks the reader through the basics of MRI, making it especially accessible to beginners. From a detailed outline of equipment prerequisites for obtaining high quality breast MRI to instructions on how to optimize image quality, expanded discussions on how to obtain optimized dynamic information.

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Breast Cancer Management and Molecular Medicine : Towards Tailored Approaches

This book provides an overview of the most recent techniques, agents and approaches for breast cancer that contribute to the individualization of treatment. Current biomedical research focuses on facilitating the transfer of molecular biology knowledge into the clinical management of patients, leading to increased survival as well as improved quality of life. Particular attention is given in this book to organ-specific tailored approaches, specific populations, patients’ preferences and rehabilitation.

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Biostatistica in radiologia : Progettare, realizzare e scrivere un lavoro scientifico radiologico = Biostatistics in Radiology: Designing, creating and writing a radiological scientific work

The progressive affirmation of evidence-based medicine requires radiology to make a qualitative leap: from demonstrating the ability to see more and better to demonstrating a significant improvement in the health or quality of life of patients.

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Biosimilars : Regulatory, clinical, and biopharmaceutical development

Provides a comprehensive overview of the biosimilar regulatory framework, the development process and clinical aspects for development of biosimilars. The development path of a biosimilar is just as unique as a development path of a new drug, tailored by the mechanism of action, the quality of the molecule, published information on the reference product, the current competitive environment, the target market and regulatory guidance, and most importantly, the emerging totality of evidence for the proposed biosimilar during development.

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Biosaline Agriculture and Salinity Tolerance in Plants

This volume focuses on reclamation, management, and utilization of salt-affected soils, their sustainable use, and evaluation of plants inhabiting naturally occurring saline habitats. It is of interest to scientists and students as well as to agricultural institutions and farmers and will undoubtedly raise the scientific community's awareness of, and interest in salinity issues.

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Biopharmaceutical processing : Development, design, and Implementation of manufacturing processes

Biopharmaceutical Processing: Development, Design, and Implementation of Manufacturing Processes covers bioprocessing from cell line development to bulk drug substances. The methods and strategies described are essential learning for every scientist, engineer or manager in the biopharmaceutical and vaccines industry. The integrity of the bioprocess ultimately determines the quality of the product in the biotherapeutics arena, and this book covers every stage including all technologies related to downstream purification and upstream processing fields. Economic considerations are included throughout, with recommendations for lowering costs and improving efficiencies.

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Biopharmaceutical manufacturing progress, trends and challenges

Source of the latest innovative research and technical development in biomanufacturing systems. It is organised into 2 parts: 1) Manufacturing of recombinant therapeutic proteins (e.g. therapeutic antibodies, biosimilars/biogenerics) and 2) Manufacturing aspects of cell and gene therapy. Each with selected chapters on the following topics for both up- and downstream, such as: Advanced process strategies, especially continuous manufacturing, Advanced culture techniques, especially single-use systems, Process transfer, scale-up/scale-down models, Processing advances/Manufacturing productivity/efficiency, Model-assisted process understanding and development/Digital Twins, Process controls and analytics, Quality control, Quality by design, Facility design and full-scale commercial systems, manufacturing technology innovation.

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Bacteriophage therapy: From lab to clinical practice

Details new and updated experimental approaches for isolating, formulating, and engineering bacteriophage medicinal products. Authored by leading experts and written in the highly successful Methods in Molecular Biology series format, each chapter includes introductions to their respective topics, lists of the necessary materials and reagents, step-by-step reproducible laboratory protocols, and valuable tips for troubleshooting and avoiding known pitfalls.

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Aquatic Biodiversity II : The Diversity of Aquatic Ecosystems

The present book comprises a unique collection of primary research papers spanning a wide range of topics in aquatic biodiversity studies, and including a first global assessment of specific diversity of freshwater animals. The book also presents a section on the interaction between scientists and science policy managers

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Applied Peritoneal Dialysis : Improving Patient Outcomes

This book offers a comprehensive guide to peritoneal dialysis (PD). Home dialysis, and more specifically PD, is growing in popularity in the US. By conservative estimates, experts suggest that 45 percent of dialysis patients in the US can be on home dialysis. However, the current penetration rate is only 10 percent. This is changing with an expected major increase in the next 5 years. One of the reasons for the low uptake is that many nephrologists lack comfort and confidence in using PD as a dialysis modality.

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Applications of Gene-Based Technologies for Improving Animal Production and Health in Developing Countries

This book will help in bridging the wide gap between developed and developing countries, in the development and use of gene-based technologies, and to elucidate the current and future roles of such technologies in the developing world. It is a good reference source for researchers, students and policy-makers alike.

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Analisi di Rasch e questionari di misura : Applicazioni in medicina e scienze sociali = Rasch analysis and measurement questionnaires: Applications in medicine and social sciences

Evaluation questionnaires are the most used tools nowadays in the field of medicine and the human sciences to evaluate variables such as disability, altruism or pain. However, clinicians are often unfamiliar with these tools. What do they really measure? How are the results to be interpreted? This book tries to answer these questions.

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Agroforestry in Europe : Current Status and Future Prospects

Brings together some of the most important current research in European agroforestry, and evaluates the current scope and future potential of agroforestry across the EU.While the majority of Europe’s agroforestry practices are currently focused in the Mediterranean, this volume draws together examples from a wide range of countries – including Greece, Spain, the UK, Hungary, Germany, Italy, the Netherlands, Switzerland, France and Slovenia. The book also covers a range of agroforestry types, including silvopastoralism – Europe’s predominant form of agroforestry – as well as alley cropping, forest farming, silvoarable systems and the use of trees for shelter. Through these examples the book also discusses the potential roles for these traditional land management systems in addressing both environmental issues such as water quality, biodiversity conservation, desertification, ecosystem services and socioeconomic issues such as rural population stabilization.

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Aging and Chronic Disorders

Aging and Chronic Disorders brings the most up-to-date answers into clear, readable focus. Focusing on the most prevalent conditions affecting older adults (diabetes, cardiovascular disease, cancer, osteoporosis, osteoarthritis, rheumatoid arthritis, low back pain, and fibromyalgia), Morewitz and Goldstein analyze disabilities and risk factors, stressors and coping strategies, treatment and rehabilitation methods, and patient education and self-management. Separate chapters are devoted to cognitive changes, psychological problems, and trends in health care utilization among seniors, and all chapters are amplified by current research findings and instructive case studies. As in their recent work.

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