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Alzheimers Disease

Alzheimer’s disease (AD) is a neurodegenerative disease that robs the minds of our elderly population. Approximately one in every eight adults over the age of 65 and nearly half of those over 85 are afflicted with this disease. The aging population in developed societies will impose an ever increasing socioeconomic threat in the future. Current medicines for AD patients are mainly symptomatic treatments and a huge unmet medical need exists to slow the progression of this disease. A great deal of research has been dedicated to understanding the pathogenesis of AD from which comes many ideas for intervening with its progression. Some of these ideas have been fast-tracked to clinical trials due to the availability of medicines with proven clinical efficacies for other diseases (e.g. atorvastatin, simvastatin, rosiglitazone and clioquinol) while others represent novel chemical entities (e.g. glycogen synthase kinase-3 inhibitors).

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Alternatives Considered But Not Disclosed : The Ambiguous Role of PowerPoint in Cross-Project Learning

This study investigates the role of PowerPoint in organizational communication, particularly in terms of a functional dilemma between its application for documentation as opposed to presentation purposes. The theoretical part of the analysis combines insights from both organizational communication studies (J. R. Taylor et al.) and social systems theory (N. Luhmann et al.). The empirical analysis shows that PowerPoint documents created for cross-project learning purposes contribute to an invisibilization rather than a visibilization of decision processes and their contingency.

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Alternative pseudodifferential analysis : With an application to modular forms

This volume introduces an entirely new pseudodifferential analysis on the line, the opposition of which to the usual (Weyl-type) analysis can be said to reflect that, in representation theory, between the representations from the discrete and from the (full, non-unitary) series, or that between modular forms of the holomorphic and substitute for the usual Moyal-type brackets. This pseudodifferential analysis relies on the one-dimensional case of the recently introduced anaplectic representation and analysis, a competitor of the metaplectic representation and usual analysis.

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Alternative Education : Global Perspectives Relevant to the Asia-Pacific Region

Alternative streams of education have been and remain an important but difficult theme for teachers, parents, policy-makers, and scholars. By focusing on case studies of six countries (Bolivia, Thailand, Australia, USA, The Netherlands, and Denmark), and by comprehensively analysing these by means of international comparative methodologies, the author approaches the nuts and bolts issues of alternative and mainstream education systems. The case studies include Charter Schools in the USA and Waldorf Schools in Australia. The study presents not only an insightful analysis of alternative forms of education with regard to actual issues in societies and also legal and administrative features of education. It provides insights into the kind of school development that could be appropriate in the 21st century and the types of educational communities we should seek to create in the age of globalisation.

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Altering nature ; Vol.2 : Religion, Biotechnology, and Public Policy

The two volumes of Altering Nature consider the complex ways that concepts of 'nature' and 'the natural' are understood and the relevance of those understandings to discussions of biotechnology.Volume Two, Religion, Biotechnology, and Public Policy, reviews recent religious and ethical analyses of four specific areas of biotechnology: assisted reproduction, genetic therapy and enhancement, human-machine incorporation, and biodiversity. It identifies and explores the richer normative themes that inform particular debates and suggests ways that policy choices in biotechnology may be illuminated by devoting greater attention to religious perspectives.

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Altering nature ; Vol.1 : Concepts of ‘Nature’ and ‘The Natural’ in Biotechnology Debates

Volume One, Concepts of 'Nature' and 'The Natural' in Biotechnology Debates, offers nuanced accounts of the ways that nature is invoked and interpreted, both descriptively and prescriptively, by different disciplines, including perspectives from spirituality and religion, philosophy, science and medicine, law and economics, and aesthetics. In the context of that broad discussion.

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Alpine Industrial Landscapes : Towards a New Approach for Brownfield Redevelopment in Mountain Regions

This book presents a pioneering research on brownfield redevelopment in mountain regions, and specifically in the European Alps. The origins and causes, the actual conditions as well as the future challenges and potentials of mountain brownfields are investigated from an interdisciplinary yet landscape-centered perspective. Through the reasoned combination of research-by-design methods and case-study analysis, the book explores the infrastructural relevance of these sites for the specific mountain territory, while advancing an innovative structuralist-systemic approach for their physical and functional transformation. The book includes, among others, a first transnational geo-mapping of Alpine brownfields, whose impressive outcomes in terms of site numbers and distribution can only confirm the urgency of this research.

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Allocating public and private resources across generations : Riding the age waves ; Vol .2

The chapters in this volume greatly develop our understanding of the nature and measurement of transfers, their motives and mechanisms, and their macro-level dimensions, especially in the context of demographic transitions.

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Alla ricerca della via più breve : Un'avventura matematica = Finding the shortest way : A mathematical adventure

Il libro narra la vicenda di Rut, quindicenne, trasferitasi da poco in Germania con la famiglia, al seguito del padre che lavora per un’azienda internazionale produttrice di Software. Sarà proprio il padre a regalare a Rut un computer nuovo, mentre a scuola attraversa un periodo di crisi.E’ l’inizio di un’avventura. Nel computer è installato Vim: un programma che ascolta, capisce e risponde alle domande che la ragazza, inizialmente incredula, fa. Raccontata da Vim, la matematica prende una forma completamente nuova, sorprendente e affascinante.

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All of Nonparametric Statistics

The goal of this text is to provide the reader with a single book where they can find a brief account of many, modern topics in nonparametric inference. The book is aimed at Master's level or Ph.D. level students in statistics, computer science, and engineering. It is also suitable for researchers who want to get up to speed quickly on modern nonparametric methods.This text covers a wide range of topics including: the bootstrap, the nonparametric delta method, nonparametric regression, density estimation, orthogonal function methods, minimax estimation, nonparametric confidence sets, and wavelets. The book has a mixture of methods and theory.

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Algoritmi : Lo spirito dell’informatica = Algorithms : The spirit of information technology

Algorithms are the heart of computer science and mathematics, since without them the use of computers would not be possible. In this book, which in its English edition has been a longtime bestseller, Harel and Feldmann answer all questions relating to this topic. They talk about the evaluation, correctness and effectiveness of algorithms, but also clarify some doubts about programming techniques and also refer to the very current discussion on quantum computing. The book is useful both as a basic text for an introductory university course in computer science, and as a general introduction to natural sciences, mathematics or engineering.

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Algorithms in Real Algebraic Geometry

The algorithmic problems of real algebraic geometry such as real root counting, deciding the existence of solutions of systems of polynomial equations and inequalities, finding global maxima or deciding whether two points belong in the same connected component of a semi-algebraic set appear frequently in many areas of science and engineering. In this first-ever graduate textbook on the algorithmic aspects of real algebraic geometry, the main ideas and techniques presented form a coherent and rich body of knowledge, linked to many areas of mathematics and computing.

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Algorithms for Fuzzy Clustering : Methods in c-Means Clustering with Applications

The main subject of this book is the fuzzy c-means proposed by Dunn and Bezdek and their variations including recent studies. We emphasize in this book is a family of algorithms using entropy or entropy-regularized methods which are less known, but we consider the entropy-based method to be another useful method of fuzzy c-means.

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Algorithms for Approximation ; Proceedings of the 5th International Conference, Chester, July 2005

Approximation methods are vital in many challenging applications of computational science and engineering. This is a collection of papers from world experts in a broad variety of relevant applications.

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Algorithmic topology and classification of 3-manifolds

This book provides a comprehensive and detailed account of different topics in algorithmic 3-dimensional topology. The book is intended to combine the pedagogical approach of a graduate textbook with the completeness and reliability of a research monograph.

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Algorithmic information theory : Mathematics of digital information processing

This book treats the Mathematics of many important areas in digital information processing.It covers, in a unified presentation, five topics: Data Compression, Cryptography, Sampling (Signal Theory), Error Control Codes, Data Reduction. The thematic choices are practice-oriented. So, the important final part of the book deals with the Discrete Cosine Transform and the Discrete Wavelet Transform, acting in image compression. The presentation is dense, the examples and numerous exercises are concrete. The pedagogic architecture follows increasing mathematical complexity.

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Algorithmic Foundations of Robotics VI

Robot algorithms are abstractions of computational processes that control or reason about motion and perception in the physical world. Because actions in the physical world are subject to physical laws and geometric constraints, the design and analysis of robot algorithms raises a unique combination of questions in control theory, computational and differential geometry, and computer science. Algorithms serve as a unifying theme in the multi-disciplinary field of robotics. This volume consists of selected contributions to the sixth Workshop on the Algorithmic Foundations of Robotics. This is a highly competitive meeting of experts in the field of algorithmic issues related to robotics and automation.

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Algorithm collections for digital signal processing applications using matlab

The Algorithms such as SVD, Eigen decomposition, Gaussian Mixture Model, HMM etc. are scattered in different fields. There is the need to collect all such algorithms for quick reference. Also there is the need to view such algorithms in application point of view. Algorithm Collections for Digital Signal Processing Applications using MATLAB attempts to satisfy the above requirement. Also the algorithms are made clear using MATLAB programs.

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Algèbre, Chapitres 1 à 3 = Algebra, Chapters 1 to 3

To do algebra is essentially to calculate, that is to say to perform, on elements of a set, (<algebraic operations n, the best-known example of which is provided by the (<four rules)) of elementary arithmetic. This is not the place to retrace the slow process of progressive abstraction by which the notion of algebraic operation, initially restricted to natural integers and to measurable quantities, gradually widened its field, as it grew. at the same time generalized the notion of ((number O, until, going beyond the latter, it came to apply to elements which no longer had any character ((numeric)>, for example to permutations of a - seems (see Historical Note in chap. 1).

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Algèbre, Chapitre 9 = Algebra, Chapter 9

Sesquilinear and quadratic forms : The Mathematics Elements of Nicolas BOURBAKI aim to provide a rigorous, systematic presentation without prerequisites of mathematics from their foundations. This ninth chapter of the Book of Algebra, the second Book of the treatise, is devoted to quadratic, symplectic or Hermitian forms and to associated groups.

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