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Bone Marrow Derived Progenitors
The ability of stem cells to acquire different desired phenotypes has opened the door for a new discipline: regenerative medicine. Much of the interest for this purpose is generated by embryonic stem cells, but their use is still controversial for moral reasons as well as scientifically. Less controversial and readily available are the adult bone marrow-derived progenitors including hematopoietic stem cells, endothelial progenitors and mesenchymal stem cells. The ambitious goal of this volume is to provide a comprehensive overview of the currently available information related to the therapeutic utility of adult bone marrow-derived cells. Each chapter has been written by an accomplished expert in the field, making this a hugely valuable resource for anyone looking for an up-to-the-minute assessment of current practice in adult bone marrow-derived cell therapy.
Bioinformatics and the cell : Modern computational approaches in genomics, proteomics and transcriptomics
"Xuhua Xia’s Bioinformatics and the Cell is a welcome addition to the bourgeoning field of bioinformatics text books. Xia stakes out a too-often neglected middle ground in bioinformatics by presenting a work that emphasizes methods’ biological utility without eschewing algorithmic formalism. Readers will find a well-rounded presentation of bioinformatics techniques employed in genomics, transcriptomics and proteomics – unified throughout by the common theme of molecular evolution."
Applied biophysics for drug discovery
It is a guide to new techniques and approaches to identifying and characterizing small molecules in early drug discovery. Biophysical methods are reasserting their utility in drug discovery and through a combination of the rise of fragment-based drug discovery and an increased focus on more nuanced characterisation of small molecule binding, these methods are playing an increasing role in discovery campaigns.
Anthropologies of Global Maternal and Reproductive Health : From Policy Spaces to Sites of Practice
This open access edited book brings together new research on the mechanisms by which maternal and reproductive health policies are formed and implemented in diverse locales around the world, from global policy spaces to sites of practice. The authors – both internationally respected anthropologists and new voices – demonstrate the value of ethnography and the utility of reproduction as a lens through which to generate rich insights into professionals’ and lay people’s intimate encounters with policy.
An introduction to generative drug discovery
Describes the state‑of‑the‑art methods and applications for de novo design of drug candidates using generative chemistry models as well as the ethical aspects of this technology. It will provide a foundation for those new to the field as well as those that may already have some experience of its utility. With contributions from scientists in both academia and industry ‘Introduction to Generative Drug Discovery’ may represent one of the earliest if not the first book to focus on this topic.
Manage IT! : Organizing IT Demand and IT Supply
Discusses the IT management tasks and the objects involved. This book outlines traditional IT management; deals with controlling IT; and, tackles the financial, personnel, purchasing, legal and security aspects in IT. It explains the effects of striving for 'utility computing' and control of IT by means of 'IT portfolio management'.
Clinical oral medicine and pathology
The book has been well received internationally by a wide audience of clinicians, including general dentists, oral surgeons, otolaryngologists, primary care physicians, nurse practitioners, dental hygienists, physician assistants, and dermatologists, and sales have been strong among students and post-graduate residents training in medical, dental, and allied health fields, supporting the versatility of this work and serving as testimony to its value in both the academic and private practice arenas. Several key updates and improvements have been made to the second edition. All informational content has been updated to ensure accuracy and relevance, particularly in the rapidly evolving fields of oncology and pharmacology. A new chapter has been added entitled "Oral Sequelae of Cancer and Cancer Therapy" which better organizes and consolidates previous content while expanding on topics such as targeted therapies and hematopoietic stem cell transplantation. Additional clinical images have been included throughout the book so that the full clinical spectrum of any given condition is well-represented. Furthermore, the print quality, as well as the positioning and layout of the clinical images has been improved for optimal utility. Lastly, the summary boxes that follow each condition have been reconfigured with color-coded icons for improved definition, ease of use and cross-referencing.
Catastrophe modeling : A new approach to managing risk
Catastrophe Modeling: A New Approach to Managing Risk is the first book that systematically analyzes how catastrophe models can be used for assessing and managing risks of extreme events. It focuses on natural disaster risk, but also discusses the management of terrorism risk. A unique feature of this book is the involvement of three leading catastrophe modeling firms, AIR Worldwide, EQECAT, and Risk Management Solutions, who examine the role of catastrophe modeling in rate setting, portfolio management and risk financing. Given the uncertainties associated with terrorism the book points out the opportunities for utilizing catastrophe models to set insurance rates and to examine public-private partnerships for providing financial assistance in the event of a terrorist attack. This book is strongly recommended for individuals who must make decisions regarding the management of impacts of catastrophe risks including those in both the public and private sector.
Advances in public economics : Utility, choice and welfare
This Festschrift in honor ofChristian Seidl combines a group of prominent authors who are experts in areas like public economics, welfare economic, decision theory, and experimental economics in a unique volume. He has dedicated most of his research to utility and decision theory, social choice theory, welfare economics, and public economics.
Advances in decision making under risk and uncertainty
Whether we like it or not we all feel that the world is uncertain. From choosing a new technology to selecting a job, we rarely know in advance what outcome will result from our decisions. Unfortunately, the standard theory of choice under uncertainty developed in the early forties and fifties turns out to be too rigid to take many tricky issues of choice under uncertainty into account. The good news is that we have now moved away from the early descriptively inadequate modeling of behavior. This book brings the reader into contact with the accomplished progress in individual decision making through the most recent contributions to uncertainty modeling and behavioral decision making. It also introduces the reader into the many subtle issues to be resolved for rational choice under uncertainty.
Lighting Design Basics, 3rd ed.
Offering fundamental concepts and prescriptive techniques in a highly visual format, this book provides clear, practical guidance on utilizing the latest in lighting techniques and technology to showcase a space without sacrificing utility. Covering more than 25 different design scenarios with in-depth rationale for proposed solutions, this book provides insightful distribution diagrams, floor plans, and details for lighting installation and construction. Real-world case studies illustrate lighting design in residential, commercial, healthcare, education, and hospitality settings, and skill-building exercises offer practice for real-world projects as well as NCIDQ and NCARB exam preparation.
Bone Morphogenetic Proteins : From Local to Systemic Therapeutics
Tissue engineering is gaining interest as it is applied for regeneration of organs to attain their lost function. Although resorbable scaffolds and progenitor cell types are required principles to engineer a functional tissue locally, the inductive signal is a prerequisite to trigger the growth and differentiation of responding cells in space and time. Bone morphogenetic proteins (BMPs), also called growth and differentiation factors (GDFs), originally identified from bone have been successfully used to regenerate the bone in humans. Most recent preclinical data suggests that BMPs have a potential to provide protection against inflammation and fibrosis in acute and chronic injury of parenchymal tissues when applied systemically to sustain the function of kidney and liver. The application of BMPs from a local to systemic utility is a rapidly growing field, gaining interest among researchers and biotech entrepreneurs.
Assessing Climate Change : Temperatures, Solar Radiation, and Heat Balance
The chapters of the book attempt to answer a number of essential questions in relation to global warming and climate change. He begins by showing how the earth’s climate has varied in the past, discussing ice ages, the Holocene period since the end of the last ice age, particularly during the past 1000 years. He investigates the reliability of "proxies" for historical temperatures and assesses the hockey stick version of global temperatures for the past millennium. To do this effectively he looks carefully at how well near surface temperatures of land and ocean on earth have been monitored during the past 100 years or more, and looks at the utility and significance of a single global average temperature
Adaptive Low-Power Circuits for Wireless Communications
Adaptive radio transceivers require a comprehensive theoretical framework in order to optimize their performance. Adaptive Low-Power Circuits for Wireless Communications provides this framework with a discussion of joint optimization of Noise Figure and Input Intercept Point in receiver systems. Original techniques to optimize voltage controlled oscillators and low-noise amplifiers to minimize their power consumption while maintaining adequate system performance are also provided. The experimental results presented at the end of the book confirm the utility of the proposed techniques.
