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Mass Vaccination : Global Aspects - Progress and Obstacles
Mass immunization is the blitzkrieg of vaccination practice. It serves to rapidly protect populations, both because of the high coverage achieved and because of the herd immunity thereby induced. However, as in war, mass immunization campaigns must be conducted intelligently, with careful strategy and strong attention to logistics of supply and deployment. If conducted badly, mass immunization may fail or even be counter-productive. In this volume, some of the most successful practitioners of mass im- nization tell us about its art and science. David Heymann and Bruce Aylward of WHO begin the book with a theoretical and practical overview of mass immunization. Michael Lane, who participated in the successful effort to eradicate smallpox relates how this was done using mass vaccination and other strategies. Application of mass immunization by the US military is c- ered by John Grabenstein and Remington Nevin, who have a large experience in these matters. Karen Noakes and David Salisbury recount the striking s- cesses of mass immunization in the United Kingdom. The global control of the clostridia that produce diphtheria toxin is described by Charles Vitek. Hepa- tis A is decreasing dramatically under the impact of large-scale vaccination, as Francis André illustrates. The French experience with Hepatitis B vac- nation has been mixed, and François Denis and Daniel Levy-Bruhl explain the circumstances. In?uenza vaccination is an annual example of large-scale campaigns, the complexity of which is recounted by Benjamin Schwartz and Pascale Wortley.
Clinical chemistry : Principles, techniques, and correlations ; 9th ed.
Keeps students at the forefront of what continues to be one of the most rapidly advancing areas of laboratory medicine with clear explanations that balance analytic principles, techniques, and correlation of results with coverage of disease states. The book not only demonstrates the how of clinical testing, but also the what, why, and when of testing correlations to help students develop the knowledge and interpretive and analytic skills they'll need in their future careers.
Cancer drug safety and public health policy : A changing landscape
Description and analysis of recent developments and current trends in health policy with regard to cancer drug safety. Opens with an overview of pharmacovigilance for cancer blockbuster drugs, covering both general considerations and efforts to develop a structured framework for the identification and reporting of adverse drug reactions (ADRs). A number of important examples of serious ADRs to hematology and oncology drugs are then reviewed, with evaluation of the lessons learned and the policy implications of the ensuing legal cases and their settlements. Further, the difficulty of reporting such blockbuster side effects in the medical literature is explored in an empirical study. Significant advances have been achieved in analytic methods for the identification of ADRs, and here there is a particular focus on the value of optimal discriminant analysis. Finally, the impacts on pharmacovigilance and drug safety of the huge fines paid under the U.S. False Claims Act relating to the defrauding of governmental programs also receive careful attention – these fines are playing an important role in changing the landscape for pharmaceutical safety.
Bisphosphonates in medical practice : Actions - side effects - indications - strategies
Clinical osteology is now an independent specialty which nevertheless encompasses all branches of medicine and effects each and every one of us: Bone is Every Body´s Business: This book has been designed as an up to date manual to deal with the currently recognized indications for bisphosphonates, to outline situations and conditions for prevention of skeletal disorders, and to provide practical guidelines for treatment. It is intended for doctors who seek precise information on bisphosphonates in medical practice to enable them to treat patients with disorders of bone or better still to avoid their occurrence .
Biomedical Informatics : Computer Applications in Health Care and Biomedicine
This series is directed to healthcare professionals who are leading the transformation of health care by using information and knowledge. Launched in 1988 as Computers in Health Care, the series offers a broad range of titles: some addressed to specific prof- sions such as nursing, medicine, and health administration; others to special areas of practice such as trauma and radiology.
Bill Ricker : An appreciation
This book is the first complete biography of one of the founders of fishery science, William Edwin (Bill) Ricker (1908 - 2001). Bill is immortalized in the Ricker Curve. He developed the Curve in his studies of stock and recruitment in fisheries, but it has been widely applied in many areas of science. Bill is best known for his contributions to fishery science, but he was also internationally recognized as an entomologist and a scientific editor. This book combines Bill’s own recollections with contributions from those who knew him and worked with him as a colleague during his multifaceted career. In an article written shortly before his death, Bill gives his own account of his career and intellectual development.
Autoimmune Diseases of the Skin : Pathogenesis, Diagnosis, Management
The book provides an overview and the latest information on the broad spectrum of cutaneous autoimmune disorders for clinicians, scientists and practitioners in dermatology, medicine, rheumatology, ENT, pediatrics and ophthalmology. The book is unique since it presents the state-of-the-art knowledge on pathophysiology, clinical diagnosis and management of these disorders provided by the world experts in the field. The primary intention is to broaden the understanding of the pathophysiology of cutaneous autoimmune disorders and to provide a practical guide to how to identify and handle these conditions. The book is illustrated with many tables, illustrative figures and clinical color photographs. The second edition has been extended by chapters on autoimmune pigmentary disorders (vitiligo), hairloss (alopecia areata) and cutaneous symptoms of rheumatic disorders.
Applied biophysics for drug discovery
It is a guide to new techniques and approaches to identifying and characterizing small molecules in early drug discovery. Biophysical methods are reasserting their utility in drug discovery and through a combination of the rise of fragment-based drug discovery and an increased focus on more nuanced characterisation of small molecule binding, these methods are playing an increasing role in discovery campaigns.
Antibiotics Simplified
Designed to bridge knowledge gained in basic sciences courses with clinical practice in infectious diseases. This practical text reviews basic microbiology and how to approach the pharmacotherapy of a patient with a presumed infection. It also contains concise Drug Class Reviews with an explanation of the characteristics of various classes of antibacterial drugs and antifungal drugs.
Java Illuminated ; 5th ed.
Provides learners with an interactive, user-friendly approach to learning the Java programming language. Comprehensive but accessible, the text takes a progressive approach to object-oriented programming, allowing students to build on established skills to develop new and increasingly complex classes. Java Illuminated follows an activity-based active learning approach that ensures student engagement and interest.
Beginning jOOQ : Learn to Write Efficient and Effective Java-Based SQL Database Operations
Learn to use the jOOQ library to manage SQL database operations in Java and JVM applications. This book walks you through what JOOQ is, how to install and get started with it, and then gets you working with it. You will: Comparing equivalent features between Hibernate, JPA and jOOQ. Unlock the power of your SQL database with high performing, flexible and typesafe SQL queries. Seamlessly work with many different SQL database vendors without changing your code. Effortlessly generate Java code based on the content of your database. Write reactive SQL database access code with R2DBC. Integrating jOOQ into popular frameworks and platforms like Hibernate, Spring boot and Quarkus tools like IDEs. Testing jOOQ-based code with modern integration testing frameworks like TestContainers and Docker. Learn how to safely handle data access code within frameworks like the Java Persistence API (JPA)
Beginning DotNetNuke 4.0 Website Creation in C# 2005 with Visual Web Developer 2005 Express : From novice to professional
The book takes you through the steps necessary to get an internal web portal running for employee use. If you have some programming experience and creativity, this book will help you expand your business presence in a short amount of time. It features simple explanations and proof-of-concept examples throughout. The book concludes with the creation of a web portlet that you can plug into an external website for a web presence.
An Introduction to Formal Languages and Automata
Designed for an introductory course on formal languages, automata, compatibility, and related matters forming what is known as the theory of computation
Civil engineering materials : From theory to practice ; 1st ed.
Presents the state-of-the-art in civil engineering materials, including the fundamental theory of materials needed for civil engineering projects and unique insights from decades of large-scale construction in China. The title includes the latest advances in new materials and techniques for civil engineering, showing the relationship between composition, structure and properties, and covering ultra-high-performance concrete and self-compacting concrete developed in China. This book provides comprehensive coverage of the most commonly used, most advanced materials for use in civil engineering. This volume consists of eight chapters covering the fundamentals of materials, inorganic cementing materials, Portland cement concrete, bricks, blocks and building mortar, metal, wood, asphalt and polymers.
Alternative concrete - geopolymer concrete : Emerging research and opportunities
Focuses on fly ash-based alkali-activated geopolymer concrete, its production and characteristic properties. The re-use of waste materials and industrial by-products, such as fly ash, is not only economically of interest but also helps to reduce carbon dioxide emissions. The carbon footprint of these materials is much lower than that of concrete using ordinary Portland cement. They thus offer new sustainable solutions to the construction industry.
Marketing ; 16th ed.
Expanded coverage on social responsibility and sustainability topics such as privacy, social entrepreneurship, diversity, equity, inclusion, and environmental impact. The 16e continues its real-world focus with “Marketing Matters,” “Making Responsible Decisions,” “Insights about me,” “Applying Marketing Metrics,” “Integration of the Customer Journey” and “Building your Marketing Plan” features throughout. Key marketplace changes related to the pandemic such as curbside pick-up, touchless payment, and delivery have been incorporated.
Building a Future with BRICs : The Next Decade for Offshoring
In 2003, Goldman Sachs published a startling report on the BRICs (Brazil, Russia, India, and China) region: These four countries would be larger than the G6 economics within 40 years, muscling their way to economic dominance over the coming decades, and powering past developed countries such as the United Kingdom, Germany, and Japan. This book focuses on the technology and technology-enabled services that underpin this social and economic revolution. The editor analyses the reasons why these four countries are in a unique position to lead a 21st century growth in international services. He then features 12 chapters written by the most important chief executives from the BRICs service economy. Indian technology leaders, such as Nandan Nilekani (Infosys), Shiv Nadar (HCL), and Rajendra Pawar (NIIT), feature alongside their peers from Brazil, Russia, and China outlining their views on the next decade for offshoring.
Architectures of festival in early modern Europe : Fashioning and re-fashioning urban and courtly space
Draws on up-to-date research by a Europe-wide group of academic scholars and museum and gallery curators to provide a unique, intellectually-stimulating and beautifully-illustrated account of temporary architecture created for festivals of the sixteenth and seventeenth centuries, together with permanent architecture pressed into service for festival occasions across major European locations including Italian, French, Austrian, Scottish and German.
Light Scattering from Polymer Solutions and Nanoparticle Dispersions
Light scattering is a very powerful method to characterize the structure of polymers and nanoparticles in solution. Recent technical developments have strongly enhanced the possible applications of this technique, overcoming previous limitations like sample turbidity or insufficient experimental time scales. However, despite their importance, these new developments have not yet been presented in a comprehensive form. In addition, and maybe even more important to the broad audience, there lacks a simple-to-read textbook for students and non-experts interested in the basic principles and fundamental techniques of light scattering. As part of the Springer Laboratory series, this book tries not only to provide such a simple-to-read and illustrative textbook about the seemingly very complicated topic of light scattering from polymers and nanoparticles in dilute solution, but also intends to cover some of the newest technical developments in experimental light scattering.
Assertion-Based Design
Chapter 3 Specifying RTL Properties 61 3. 3 Declarative versus procedural 67 3. 3 RTL assertion specification techniques 68 RTL invariant assertions 69 3. 2 Declaring properties with PSL 72 RTL cycle related assertions 73 3. 3 3. 1 Immediate assertions 84 3. 3 System functions 95 3. 3 Assertions across simulation time slots 111 4.
