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Magnetic Resonance of Myelination and Myelin Disorders
The book has been extensively revised and expanded to do justice to the rapid advances in MR technology, molecular biochemistry, and genetics and the discovery of new disease entities with prominent white matter involvement. Forty chapters have been added, and the number of illustrations has risen considerably. The ability to confirm the presence of genetic alterations in a number of disorders allows more advantageous presentation of the phenotypic variation as expressed in differ.
Chemokines and Viral Infection
This edition of Current Topics in Microbiology and Immunology examines the role of chemokines and chemokine receptors in host defense and disease development following viral infection. Chemokines represent a family of over 40 small proteins that, for the most part, are secreted into the environment and function by binding to G protein-coupled receptors (GPCRs) that are expressed on numerous different cell types. When initially identified close to 30 years ago, these molecules were associated with various human inflammatory diseases and it was recognized that expression may be integral in leukocyte recruitment to inflamed tissue. There are now four sub-families of chemokines identified based on defined structural criteria relating to the positional location of conserved cysteine residues within the amino-terminus of the protein. Chemokines are now recognized as important in numerous biological processes ranging from maintaining the organizational integrity of secondary lymphoid tissue to participating in various aspects of both innate and adaptive immune responses following microbial infection. With this in mind, this book highlights the functional roles of chemokines and their receptors in participating in various aspects of the immune response against well-known viral pathogens.
Ken Smith Landscape Architect : Urban projects
Ken Smith is one of the most interesting voices in landscape architecture today. His works reflect the intensity and energy of their surroundings and challenge the distinction between landscape and art. Ken Smith Landscape Architect/Urban Projects focuses on three prominent works in New York City: the East River Ferry Landings, P.S. 19, and a roof garden for the Museum of Modern Art. Featuring an interview with Ken Smith and extensive photographic documentation and drawings, as well as an essay by Nina Rappaport and a foreword by Peter Reed, the book reveals how each project expresses new relationships between landscape and place within the city
Architectures of festival in early modern Europe : Fashioning and re-fashioning urban and courtly space
Draws on up-to-date research by a Europe-wide group of academic scholars and museum and gallery curators to provide a unique, intellectually-stimulating and beautifully-illustrated account of temporary architecture created for festivals of the sixteenth and seventeenth centuries, together with permanent architecture pressed into service for festival occasions across major European locations including Italian, French, Austrian, Scottish and German.
Mathematical Events of the Twentieth Century
Russian mathematics (later Soviet mathematics, and Russian mathematics once again) occupies a special place in twentieth-century mathematics. In addition to its well-known achievements, Russian mathematics established a unique style of research based on the existence of prominent mathematical schools. These schools were headed by recognized leaders, who became famous due to their talents and outstanding contributions to science. The present collection is intended primarily to gather in one book the t- timonies of the participants in the development of mathematics over the past century. In their articles the authors have expressed their own points of view on the events that took place. The editors have not felt that they had a right to make any changes, other than stylistic ones, or to add any of their own commentary to the text. Naturally, the points of view of the authors should not be construed as those of the editors. The list of mathematicians invited to participate in the present edition was quite long.
Linear and Nonlinear Programming
"Linear and Nonlinear Programming" is considered a classic textbook in Optimization. While it is a classic, it also reflects modern theoretical insights. These insights provide structure to what might otherwise be simply a collection of techniques and results, and this is valuable both as a means for learning existing material and for developing new results. One major insight of this type is the connection between the purely analytical character of an optimization problem, expressed perhaps by properties of the necessary conditions, and the behavior of algorithms used to solve a problem. This was a major theme of the first and second editions. Now the third edition has been completely updated with recent Optimization Methods. Yinyu Ye has written chapters and chapter material on a number of these areas including Interior Point Methods.
La musica del Big Bang : Come la radiazione cosmica di fondo ci ha svelato i segreti dell’Universo = The music of the Big Bang : How the cosmic background radiation revealed the secrets of the Universe to us
Cosmic microwave background radiation is the residue of the great heat following the Big Bang. A tenuous sign, over 13 billion years old, in which the answers to many of the questions about the nature of our Universe are hidden. Discovered by chance in 1964, in the last forty years this fossil trace of the origins of the Cosmos has been explored with every available means. Two Nobel Prizes in physics have already been awarded for research involving it, the last in 2006 for the results of the COBE satellite. Much of the information encoded in the cosmic background radiation was impressed by the superimposition of acoustic waves present in the early Universe: a "music" of the Big Bang, which cosmologists have tried for years to reconstruct, using techniques similar to those that allow to distinguish the sound of different musical instruments. Only recently have the first notes of this extraordinary cosmic symphony finally been revealed, but the investigation is not over yet. This book illustrates, with a language suitable even for non-specialists, the theories, observations and discoveries that have brought cosmology into a new era.
La correspondance entre Henri Poincaré et les physiciens, chimistes et ingénieurs = The correspondence between Henri Poincaré and physicists, chemists and engineers
Cosmic microwave background radiation is the residue of the great heat following the Big Bang. A tenuous sign, over 13 billion years old, in which the answers to many of the questions about the nature of our Universe are hidden. Discovered by chance in 1964, in the last forty years this fossil trace of the origins of the Cosmos has been explored with every available means. Two Nobel Prizes in physics have already been awarded for research involving it, the last in 2006 for the results of the COBE satellite. Much of the information encoded in the cosmic background radiation was impressed by the superimposition of acoustic waves present in the early Universe: a "music" of the Big Bang, which cosmologists have tried for years to reconstruct, using techniques similar to those that allow to distinguish the sound of different musical instruments. Only recently have the first notes of this extraordinary cosmic symphony finally been revealed, but the investigation is not over yet. This book illustrates, with a language suitable even for non-specialists, the theories, observations and discoveries that have brought cosmology into a new era.
Basic principles and applications of probability theory
This introductory chapter discusses such notions as determinism, chaos and randomness, p- dictibility and unpredictibility, some initial approaches to formalizing r- domness and it surveys certain problems that can be solved by probability theory. This will perhaps give one an idea to what extent the theory can - swer questions arising in speci?c random occurrences and the character of the answers provided by the theory. 1. 1 The Nature of Randomness The phrase “by chance” has no single meaning in ordinary language. For instance, it may mean unpremeditated, nonobligatory, unexpected, and so on. Its opposite sense is simpler: “not by chance” signi?es obliged to or bound to (happen). In philosophy, necessity counteracts randomness. Necessity signi?es conforming to law – it can be expressed by an exact law. The basic laws of mechanics, physics and astronomy can be formulated in terms of precise quantitativerelationswhichmustholdwithironcladnecessity.
Annual bibliography of the history of the printed book and libraries ; Vol.31 : Publications of 2000 and additions from the preceding years
The Annual Bibliography of the History of the Printed Book and Libraries aims at recording articles of scholarly value which relate to the history of the printed book, to the history of arts, crafts, techniques and equipment, and of the economic social and cultural environment, involved in its production, distribution, conservation and description.
Ages, generations and the social contract : The demographic challenges facing the welfare state
Our societies are ageing. The Family is changing. Labour force behaviour is evolving. How is the organisation of family and collective solidarity adapting in this context of longer life spans, low fertility, and work that is simultaneously scarce and abundant? The welfare states are currently facing three main challenges: ensure satisfactory living conditions for the elderly without increasing the cost burden on the active population, reduce social inequality, and maintain equity between successive generations. In this book, researchers from different countries compare their experiences and offer contrasting views on the future of social protection. They consider the theoretical aspects of the intergenerational debate, relations between generations within the family, the living standards of elderly people, and the question of social time.
