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Bioinformatics and the cell : Modern computational approaches in genomics, proteomics and transcriptomics

"Xuhua Xia’s Bioinformatics and the Cell is a welcome addition to the bourgeoning field of bioinformatics text books. Xia stakes out a too-often neglected middle ground in bioinformatics by presenting a work that emphasizes methods’ biological utility without eschewing algorithmic formalism. Readers will find a well-rounded presentation of bioinformatics techniques employed in genomics, transcriptomics and proteomics – unified throughout by the common theme of molecular evolution."

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Bioelectromagnetics current concepts : The mechanisms of the biological effect of extremely high power pulses

Proceedings of the NATO Advanced Research Workshop on The Mechanisms of the Biological Effect on Extra High Power Pulses (EHPP), Yerevan, Armenia 3 - 5 March 2005

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Mathematical Linguistics

Mathematical Linguistics introduces the mathematical foundations of linguistics to computer scientists, engineers, and mathematicians interested in natural language processing. The book presents linguistics as a cumulative body of knowledge from the ground up, with no prior knowledge of linguistics being assumed, covering more than the average two-semester introductory course in linguistics.This comprehensive, reader-friendly volume offers readers a high-level orientation, discussing the foundations of the field and presenting both the classical work and the most recent results. It covers an extremely rich array of topics including not only syntax and semantics but also phonology and morphology, probabilistic approaches, complexity, learnability, and the analysis of speech and handwriting.

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Markov Models for Pattern Recognition : From Theory to Applications

Describes the underlying theoretical concepts - covering Hidden Markov models and Markov chain models - and presents the techniques and algorithmic solutions essential to creating real world applications. The actual use of Markov models in their three main application areas - namely speech recognition, handwriting recognition, and biological sequence analysis - is presented with examples of successful systems.

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Machine Learning in Computer Vision

The goal of this book is to address the use of several important machine learning techniques into computer vision applications. An innovative combination of computer vision and machine learning techniques has the promise of advancing the field of computer vision, which contributes to better understanding of complex real-world applications. The effective usage of machine learning technology in real-world computer vision problems requires understanding the domain of application, abstraction of a learning problem from a given computer vision task, and the selection of appropriate representations for the learnable (input) and learned (internal) entities of the system. In this book, we address all these important aspects from a new perspective: that the key element in the current computer revolution is the use of machine learning to capture the variations in visual appearance, rather than having the designer of the model accomplish this. As a bonus, models learned from large datasets are likely to be more robust and more realistic than the brittle all-design models.

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Machine Learning for Multimedia Content Analysis

Challenges in complexity and variability of multimedia data have led to revolutions in machine learning techniques. Multimedia data, such as digital images, audio streams and motion video programs, exhibit richer structures than simple, isolated data items. A number of pixels in a digital image collectively conveys certain visual content to viewers. A TV video program consists of both audio and image streams that unfold the underlying story.  To recognize the visual content of a digital image, or to understand the underlying story of a video program, we may need to label sets of pixels or groups of image and audio frames jointly.

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Machine Learning for Audio, Image and Video Analysis : Theory and Applications

The book is organized in four parts: The first focuses on technical aspects, basic mathematical notions and elementary machine learning techniques. The second provides an extensive survey of most relevant machine learning techniques for media processing, while the third part focuses on applications and shows how techniques are applied in actual problems. The fourth part contains detailed appendices that provide notions about the main mathematical instruments used throughout the text

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Biometrics, Computer Security Systems and Artificial Intelligence Applications

This book presents the most recent achievements in some fascinating and rapidly developing fields within Computer Science. The scientific works presented in this book have been partitioned into three topical groups: Image Analysis and Biometrics, Computer Security Systems, and Artificial Intelligence and Applications. Image Analysis and Biometrics is the branch of Computer Science dealing with the very difficult task of artificial, visual perception of objects and surroundings, as well as the problems connected with it. Computer Security and Safety is at present a very important and intensively investigated branch of Computer Science because of the menacing activity of hackers and computer viruses.

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Bayesian Networks and Decision Graphs

Probabilistic graphical models and decision graphs are powerful modeling tools for reasoning and decision making under uncertainty. As modeling languages they allow a natural specification of problem domains with inherent uncertainty, and from a computational perspective they support efficient algorithms for automatic construction and query answering. This includes belief updating, finding the most probable explanation for the observed evidence, detecting conflicts in the evidence entered into the network, determining optimal strategies, analyzing for relevance, and performing sensitivity analysis. The book introduces probabilistic graphical models and decision graphs, including Bayesian networks and influence diagrams.It contians two parts. The first part focuses on probabilistic graphical models. Compared with the previous book, the new edition also includes a thorough description of recent extensions to the Bayesian network modeling language, advances in exact and approximate belief updating algorithms, and methods for learning both the structure and the parameters of a Bayesian network. The second part deals with decision graphs, and in addition to the frameworks described in the previous edition, it also introduces Markov decision processes and partially ordered decision problems.

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Algorithms in Bioinformatics : Theory and Implementation

Explores a comprehensive and insightful treatment of the practical application of bioinformatic algorithms in a variety of fields. Delivers a fulsome treatment of some of the main algorithms used to explain biological functions and relationships. It introduces readers to the art of algorithms in a practical manner which is linked with biological theory and interpretation. The book covers many key areas of bioinformatics, including global and local sequence alignment, forced alignment, detection of motifs, Sequence logos, Markov chains or information entropy. Other novel approaches are also described, such as Self-Sequence alignment, Objective Digital Stains (ODSs) or Spectral Forecast and the Discrete Probability Detector (DPD) algorithm. Readers will also benefit from the inclusion of: A detailed presentation of new methods, such as Self-sequence alignment, Objective Digital Stains and Spectral Forecast ; A treatment of sequence alignment, including local sequence alignment, global sequence alignment and forced sequence alignment with full implementations ; Discussions of position-specific weight matrices, including the count, weight, relative frequencies, and log-likelihoods matrices ; A detailed presentation of the methods related to Markov Chains as well as a description of their implementation in Bioinformatics and adjacent fields ; An examination of information and entropy, including sequence logos and explanations related to their meaning ; A chapter on philosophical transactions that allows the reader a broader view of the prediction process ; Extensive worked examples with detailed case studies that point out the meaning of different results

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Advances in Metaheuristics for Hard Optimization

The book gathers contributions related to the following topics: theoretical developments in metaheuristics; adaptation of discrete metaheuristics to continuous optimization; performance comparisons of metaheuristics; cooperative methods combining different approaches; parallel and distributed metaheuristics for multiobjective optimization; software implementations; and real-world applications.

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Kanban-Controlled Manufacturing Systems

Kanban control systems bear a great potential to significantly improve operations. A company may reap the full benefits of kanban control only after determining an optimal or near-optimal system configuration. To do that, methods are needed to evaluate the performance and operating costs of individual system configurations. We propose an innovative construction-kit approach that enables us to build stochastic analytical models of a large class of single- and multi-product kanban systems. The presented construction-kit approach may be extended and augmented in various directions

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Analysis, Control and Optimization of Complex Dynamic Systems

Analysis, Control and Optimization of Complex Dynamic Systems gathers in a single volume a spectrum of complex dynamic systems related papers written by experts in their fields, and strongly representative of current research trends. Complex systems present important challenges, in great part due to their sheer size which makes it difficult to grasp their dynamic behavior, optimize their operations, or study their reliability. Yet, we live in a world where, due to increasing inter-dependencies and networking of systems, complexity has become the norm. With this in mind, the volume comprises two parts. The first part is dedicated to a spectrum of complex problems of decision and control encountered in the area of production and inventory systems. The second part is dedicated to large scale or multi-agent system problems occurring in other areas of engineering such as telecommunication and electric power networks, as well as more generic context.

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Markov Processes, Brownian Motion, and Time Symmetry

The book consists of two parts. Part I,This part introduces strong Markov processes and their potential theory. In particular,it studies Brownian motion, and shows how it generates classical potential theory.Part II, focus on the effects of time reversal, duality, and time-symmetry on potential theory. Certain theorems in Part I are re-proved in Part II under slightly weaker hypotheses. The volume is very useful for people who wish to learn Markov processes but it seems to the reviewer that it is also of great interest to specialists in this area who could derive much stimulus from it. One can be convinced that it will receive wide circulation." (Mathematical Reviews)

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Markov Decision Processes with Their Applications

Markov decision processes (MDPs), also called stochastic dynamic programming, were first studied in the 1960s. MDPs can be used to model and solve dynamic decision-making problems that are multi-period and occur in stochastic circumstances. There are three basic branches in MDPs: discrete-time MDPs, continuous-time MDPs and semi-Markov decision processes. Starting from these three branches, many generalized MDPs models have been applied to various practical problems. These models include partially observable MDPs, adaptive MDPs, MDPs in stochastic environments, and MDPs with multiple objectives, constraints or imprecise parameters.

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Markov Chains : Models, Algorithms and Applications

Markov chains are a particularly powerful and widely used tool for analyzing a variety of stochastic (probabilistic) systems over time. This monograph will present a series of Markov models, starting from the basic models and then building up to higher-order models. Included in the higher-order discussions are multivariate models, higher-order multivariate models, and higher-order hidden models. In each case, the focus is on the important kinds of applications that can be made with the class of models being considered in the current chapter. Special attention is given to numerical algorithms that can efficiently solve the models. Therefore, Markov Chains: Models, Algorithms and Applications outlines recent developments of Markov chain models for modeling queueing sequences, Internet, re-manufacturing systems, reverse logistics, inventory systems, bio-informatics, DNA sequences, genetic networks, data mining, and many other practical systems.

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Lectures on Probability Theory and Statistics : Ecole d'Eté de Probabilités de Saint-Flour XXXIII - 2003

Contains two of the three lectures that were given at the 33rd Probability Summer School in Saint-Flour (July 6-23, 2003). Amir Dembo’s course is devoted to recent studies of the fractal nature of random sets, focusing on some fine properties of the sample path of random walk and Brownian motion. In particular, the cover time for Markov chains, the dimension of discrete limsup random fractals, the multi-scale truncated second moment and the Ciesielski-Taylor identities are explored. Tadahisa Funaki’s course reviews recent developments of the mathematical theory on stochastic interface models, mostly on the so-called nabla varphi interface model. The results are formulated as classical limit theorems in probability theory, and the text serves with good applications of basic probability techniques.

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Le raisonnement bayésien : Modélisation et inférence = Bayesian reasoning : Modeling and inference

Describes in detail the practice of the Bayesian statistical approach using many examples chosen for their educational interest. The first part gives the general principles of statistical modeling making it possible to supervise but also to come to the aid of the imagination of the apprentice modeler. By examining examples of increasing difficulty, the reader forges the keys to building their own model. The second part presents the most useful calculation algorithms for estimating the unknowns of the model. Each inference method is presented and illustrated by numerous application cases.

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Le choix bayésien: Principes et pratique

Covers the so-called Bayesian approach to statistical inference and in particular its decision-making aspects. The bases of this axiomatics (choice of the a priori, optimal decisions, tests and regions of confidence) are discussed in detail, as well as more recent openings of Bayesian analysis such as the choice of models, the use of numerical methods. Stochastic approximation (MCMC), the theory of noninformative laws (Berger-Bernardo axioms) and the relation to the classical theory of admissibility. Each chapter is completed by an extensive series of exercises of increasing difficulty and by bibliographical notes on the themes addressed. This book can be used in a Master's program in Applied Mathematics, Biometrics, Econometrics or any other program that uses quantitative information processing techniques. It only requires a basic course in probability theory and mathematical statistics as a preliminary.

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Calcolo stocastico per la finanza = Stochastic Calculation for Finance

Offers an introduction to the mathematical, probabilistic and numerical methods that are the basis of the models for the valuation of derivative instruments, such as options and futures, dealt with in modern financial markets. The book is aimed at readers with scientific training, wishing to develop skills in the field of stochastic calculus applied to finance.

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