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A History of Physical Theories of Comets, From Aristotle to Whipple
The book describes the major physical theories of comets in the past two millennia. It demonstrates the evolution of ideas about the nature, position, motion and physical constitution of comets from Aristotle to Whipple. Unlike the available works on the history of comets, which either illustrate relatively short periods in the history of physical cometology or portray a landscape view without adequate details, the present study focuses on details of each theory. It also investigates the interaction between observational and mathematical astronomy, and the physical sciences in defining the properties of comets.
Marine Anthropogenic Litter
This book describes how man-made litter, primarily plastic, has spread into the remotest parts of the oceans and covers all aspects of this pollution problem from the impacts on wildlife and human health to socio-economic and political issues. Marine litter is a prime threat to marine wildlife, habitats and food webs worldwide. The book illustrates how advanced technologies from deep-sea research, microbiology and mathematic modelling as well as classic beach litter counts by volunteers contributed to the broad awareness of marine litter as a problem of global significance. The authors summarise more than five decades of marine litter research, which receives growing attention after the recent discovery of great oceanic garbage patches and the ubiquity of microscopic plastic particles in marine organisms and habitats.
Mangroves and Halophytes : Restoration and Utilisation
Focusing on Venezuela and Mexico, this edited volume from the International Society of Halophyte Utilisation (ISHU) explores the environmental issues facing South and Central America's coastal ecosystems, and discusses the uses of mangrove species and other halophytes in addressing issues of both coastal pollution and upland soil salinisation. The book draws on expertise from Europe and South America to present a series of case studies that detail Venezuela’s saline ecosystems and examine the economic potential of mangrove restoration and halophyte production. It includes cutting-edge research into the establishment of new mangrove stands which could serve as prototypes for the sustainable use of halophytes, including Chenopodium quinoa and Tamarix aphylla. Moreover, the detailed examples from Venezuela and other Caribbean countries provide useful models for comparison with halophyte utilisation in other parts of the world – especially the Mediterranean region, where much of the earlier research of the ISHU had been conducted.
Magnetic Resonance Tomography
Provides a comprehensive overview of both the physics and the clinical applications of MRI, including practical guidelines for imaging. The authors define the importance of MRI in the diagnosis of several disease groups in comparison or combination with other methods.
Liver Immunology : Principles and Practice
parasitic and viral infections of the liver, autoimmune liver disease, alcoholic and nonalcoholic fatty liver diseases, and transplantation in an easy-to-read and thorough format. Authors also address the key issues that have arisen in this field in recent years, including physiological roles of hepatocytes, sinusoidal lining cells, activated macrophages (Kupffer cells), cholangiocytes and stellate cells, and their modulation of T cells, natural killer (NK) cells and NKT cells.
Listeria Monocytogenes : Pathogenesis and Host Response
This comprehensive volume, written by experts in the field, includes concise and timely reviews of Listeria monocytogenes, one of the most intensively studied bacterial pathogens. Listeria monocytogenes is the cause of listeriosis, a potentially fatal disease that arises from the consumption of contaminated food. During the past two decades, studies of this organism have uncovered a wealth of information on its virulence factors, its genome organization, and its interactions with host cells and the immune system.
Les infections urinaires = Urinary tract infections
Les Infections urinaires provides an update on knowledge concerning the epidemiology of community-based infection, on the mechanisms of bacterial resistance and on certain aspects of the disease useful to urologists as well as infectious diseases, gynecologists, emergency physicians and attending physicians. . Nosocomial urinary tract infection is approached from the perspective of risk factors. Acute and chronic prostatitis was the subject of a consensus conference supported by the World Health Organization within the framework of the International Consensus Conferences in Urology in Paris. The full text and the recommendations are reported with the consent of their authors. This book is an author's book and not an author's book because urinary tract infection is multiple, complex and justifies a multidisciplinary approach.
Lake Verevi, Estonia : A highly stratified hypertrophic lake
The present book summarises investigations on Lake Verevi (surface 12.6 ha, mean depth 3.6 m). The seventeen articles in this issue deal with a wide range of questions, starting with a holistic overview of the ecological status, over assessments of long-term changes in biotic and abiotic conditions and finishing with proposed restoration plans. Abiotic chapters provide calculations on water and mass balance, distribution and fractions of phosphorus in the sediment, optical properties and penetration of radiation in the water column, sedimentation rate during the formation of stratification, and nitrogen circulation characteristics.
Common Chinese materia medica ; Vol.7
Describes 247 species of 9 families of medicinal plants, which are commonly used in Chinese medicine. The most important species are Adina rubella, Gardenia jasminoides, Hedyotis diffusa, Morinda officinalis, Rubia cordifolia, Uncaria hirsuta, Uncaria macrophylla, Uncaria rhynchophylla, Uncaria sessilifructus, Uncaria sinensis of Rubiaceae; Lonicera confusa, Lonicera hypoglauca, Lonicera macranthoides, Lonicera japonica of Caprifoliaceae; Patrinia scabiosaefolia, Patrinia villosa, Nardostachys jatamansi of Valerianaceae; Dipsacus asperoides of Dipsacaceae; Arctium lappa, Artemisia annua, Artemisia argyi, Artemisia capillaris, Artemisia scoparia, Atractylodes lancea, Atractylodes macrocephala, Dendranthema indicum, Dendranthema morifolium, Eupatorium chinense, Eupatorium fortunei, Inula helenium, Saussurea costus, Saussurea involucrata, Senecio scandens, Serratula chinensis, Siegesbeckia orientalis, Solidago decurrens, Taraxacum mongolicum, Tussilago farfara、Xanthium sibiricum of Compositae; Gentiana crassicaulis, Gentiana manshurica, Gentiana rigescens, Gentiana scabra, Swertia pseudochinensis of Valerianaceae; Lysimachia christinae of Primulaceae and Plantago asiatica of Plantaginaceae.
Common Chinese Materia Medica ; Vol.4
Describes 256 species of medicinal plants from 5 families, which are commonly used in Chinese medicine. The most important species are Agrimonia pilosa, Amygdalus persica, Armeniaca mume, Armeniaca vulgaris, Armeniaca sibirica, Chaenomeles sinensis, Eriobotrya japonica of Rosaceae; Chimonanthus praecox of Calycanthaceae；Albizia julibrissin, Archidendron clypearia, Entada phaseoloides, Bauhinia championii of Mimosoideae; Caesalpinia sappan, Cassia tora, Gleditsia sinensis of Caesalpiniaceae; Abrus cantoniensis, Astragalus membranaceus, Astragalus membranaceus, Dalbergia odorifera, Desmodium caudatum, Desmodium styracifolium, Erythrina variegata, Euchresta japonica, Flemingia prostrata, Glycyrrhiza uralensis, Glycyrrhiza inflata, Glycyrrhiza glabra, Lablab purpureus, Sophora japonica and Spatholobus suberectus of Butterflyaceae. In each specie, it introduces the scientific names, medicinal names, morphologies, habitats, distributions, acquisition and processing methods of these medicinal plants, the content of medicinal properties, therapeutic effects, usage and dosage of these medicinal plants, and attaches unedited color pictures and pictures of part herbal medicines of each species. This book series has 10 volumes in total, which covers over 2000 kinds of Chinese medicines that are commonly used. These volumes not only introduce the efficacy function and some prescriptions of the medicines, but also introduce the biological characteristics of them in detail with clear photos of the habitats, so that readers can identify them in the field. Apart from the growing environment, the books expound the distribution areas and other information to facilitate researches and other applications. The volumes are targeted at readers of general interests and it is also of high referential value for scientific researcher and teachers. It can be used as a guide to researchers, clinical doctors, and students in the department of pharmaceutics and traditional Chinese medicine.
Chronic Lymphocytic Leukemia
Chronic lymphocytic leukaemia (CLL) is the most common leukaemia in the Western world. It is also the prototype of B-cell chronic lymphoid malignancies and of their ramifications within the fields of hematology, immunology and oncology. developments of basic science into effective new approaches to the patient.
Cancer Proteomics : From Bench to Bedside
the authors collectively provide the current status of proteomics in cancer therapy and offers the existing technologies used in proteomics that allow for protein profiling and for the identification of druggable targets in human samples. Mass spectrometry based protein characterization and protein microarrays hold great promise of predicting response to specific drugs in cancer therapy. Insightful to the reader with broad perspectives on topics related to the use of proteomic strategies in cancer therapy, Cancer Proteomics offers anticipated challenges that may arise from its application in daily practice.
Cancer Chemotherapy in Clinical Practice
This book summarises the whole range of systemic cancer therapies, explaining their mode of action and potential side-effects, as well as their clinical applications.
Calcium Signalling and Disease : Molecular Pathology of Calcium
This topic is a new entry in the area of cellular calcium signaling: yet, it now spans the entire area, with discoveries that cover both genetic and acquired pathologies, even offering glimpses in the direction of therapy.Cellular calcium homeostasis, and thus calcium signalling, is mainly regulated by membrane intrinsic proteins and calcium sensor proteins. Both classes may be involved in pathological processes that affect both human and animals, ranging from common and important diseases (e.g. migraine, diabetes, epilepsia, manic depression, infertility, various types of cancer, Alzheimer’s disease, muscular dystrophy) to rare genetic conditions (e.g., a number of genetic heart conditions, autoimmune retinopathies, night blindness, hereditary amyloid polyneuropathy, malignant hyperthermia, cerebellar ataxia, atherothrombotic disease).
Botrytis : Biology, Pathology and Control
The book is the result of intensive work of 43 authors, all of them leading scientists in the Botrytis sciences. New technologies have arisen that when applied to long-standing problems or to test new hypotheses have been most rewarding and many of these are covered in this book.
Assessing Race, Ethnicity and Gender in Health
Where there are patients, clients, or study participants, there are data. And when data involve personal variables of race, ethnicity, gender, and/or sexual orientation, questions of relevance and marginalization often arise. Assessing Race, Ethnicity, and Gender in Health brings needed clarity to the debate by identifying the ethical issues as well as the technical challenges inherent in measuring these elusive concepts.
Artificial oxygen carrier; its frontline
This volume of the Keio University International Symposia for Life Sciences and Medicine contains the proceedings of the 13th symposium held under the sponsorship of the Keio University Medical Science Fund. The fund was est- lished by the generous donation of the late Dr. Mitsunada Sakaguchi. The Keio University International Symposia for Life Sciences and Medicine constitute one of the core activities sponsored by the fund,of which the objective is to contribute to the international community by developing human resources, promoting scienti?c knowledge, and encouraging mutual exchange. Each year, the Committee of the International Symposia for Life Sciences and Medicine selects the most signi?cant symposium topics from applications received from the Keio medical community. The publication of the proce- ings is intended to publicize and distribute the information arising from the lively discussions of the most exciting and current issues presented during the symposium.
Applications of nanotechnology in drug discovery and delivery
Presents complete coverage of the application of nanotechnology in the discovery of new drugs and efficient target delivery of drugs. The book highlights recent advances of nanotechnology applications in the biomedical sciences, starting with chapters that provide the basics of nanotechnology, nanoparticles and nanocarriers. Part II deals with the application of nanotechnology in drug discovery, with an emphasis on enhanced delivery of pharmaceutical products, with Part III discussing toxicological and safety issues arising from the use of nanomaterials
Animal Models of T Cell-Mediated Skin Diseases
Pharmaceutical companies are spending increasing amounts of money on drug discovery and development. Nevertheless, attrition rates in clinical development are still very high, and up to 90% of new compounds fail in clinical phase I - III trials, which is partially due to lack of clinical efficacy. This indicates a strong need for highly predictive in vitro and in vivo models. The "50th International Workshop of the Ernst Schering Research Foundation" focussed on "Animal Models of T Cell-Mediated Skin Diseases". Such animal models should have impact not only on inflammatory dermatoses but also on other inflammatory disorders due to their model character. The current volume summarises recent advances in animal research that are important for anti-inflammatory drug discovery.
Anatomical Imaging : Towards a New Morphology
This book presents selected works of contemporary evolutionary morphologists and includes such topics as broad scale reconstructions of the brain and ear of dinosaurs, inference of locomotor habits from cancellous bone architecture in fossil primates, and a comparison of the independently evolved manipulating apparatuses in the lesser and giant pandas. Insight is provided into the application of modern noninvasive technologies, including digital imaging techniques and virtual 3D reconstruction, to the investigation of complex anatomical features and coherences. In combination with traditional methods, this allows for the formulation of improved hypotheses on coordinated function and evolution. The creation of virtual translucent specimens makes it possible to realize the age-old dream of the classical anatomists: looking through the skin into the inner organization of an organism. On full display here is the dramatic and promising impact that modern imaging techniques have on scientific progress in evolutionary morphology.
