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La genetica nell’infertilità maschile = Genetics in male infertility
The notable recent cognitive advances in the field of cytogenetics and molecular genetics have made it possible to identify chromosomal anomalies and gene mutations responsible for numerous male infertility, which were completely ignored until recently. The fact is not without relevance, if the principle is valid that the recognition of the causes of a disease is also the first and necessary approach towards its correct therapy. With this publication, the authors wanted to offer specialists working in the field of assisted reproduction an update on this complex subject, dealing with both genetic causes in male infertility and infertility in genetic diseases.
Knowledge for Governance
Focuses on theoretical and empirical intersections between governance, knowledge and space from an interdisciplinary perspective. The contributions elucidate how knowledge is a prerequisite as well as a driver of governance efficacy, and conversely, how governance affects the creation and use of knowledge and innovation in geographical context.
Judges and Adjudication in Constitutional Democracies : A View from Legal Realism
Offers contributions to a philosophical and realistic approach to the place of adjudication in contemporary constitutional democracies. Bringing together scholars from different legal and philosophical backgrounds, purports to cast light on the role(s) of judges and the function of judicial interpretation inside of constitutional states, from the standpoint of legal realism as a revisited and sophisticated jurisprudential outlook. In so doing, also copes with a few major jurisprudential issues, like, e.g., determining the ideas that make up the core of legal realism, exploring the relation between legal realism and legal positivism, identifying the boundaries of judicial interpretation as they appear from a realist standpoint, as well as considering some skeptical outlooks on the very claims of contemporary legal realism.
Japan’s Arduous Rejuvenation as a Global Power : Democratic Resilience and the US-China Challenge
This book assesses the profound impact of Japan’s aspirations to become a great power on Japanese security, democracy and foreign relations. Rather than viewing the process of normalization and rejuvenation as two decades of remilitarization in face of rapidly changing strategic environment and domestic political circumstances, this volume contextualizes Japan’s contemporary international relations against the longer grain of Japanese historical interactions.It also submits that an improvement in Japan-China relations would enhance rather than detract Japan-US relations and that Tokyo will find that her new found automony in the US-Japan alliance would not only accord her more political respect and strategic latitude, but also allow her to ameliorate the excesses of American foreign policy adventurism, paving for her to become a truly normal great power.
Comparative Environmental Politics
The book explores five major topics: state-society relations; environmental non-governmental organizations (ENGOs); Green parties and environmental movements; institutions of government and policy-making; variations in the capacities of states to protect the environment; and national responses to global problems. It compares and contrasts rich and poor nations, large and small countries, liberal democracies and authoritarian states.
Comparative and Global Pedagogies : Equity, Access and Democracy in Education
This book critically examines equality, equity and democracy in education, globally as well as from various perspectives. Globally, there are increasing arguments both for the democratization of education and for the use of education to promote a democratic society. It is argued that democratic schools would better prepare for active citizenship and for a strong civil society which are seen to be the foundation of a democratic state. The book further argues that while there are inspiring examples of schools that engage in peace education or emancipatory pedagogy that work across various ethnic or religious divides, on balance, the forms, structures, ideologies and purposes of formal education interact to make national and international conflict more likely.
Clinical nuclear medicine
Clinical Nuclear Medicine … focuses on the universal state of the art in both diagnostic and therapeutic radionuclide methodology. … This book is easily readable, with presentation of essential points and plentiful references, and the quality of the figures and tables is excellent. … is a useful guide to students, technologists, and practitioners in nuclear medicine and radiology, as well as to general physicians who request nuclear diagnosis or treatment. … will be a welcome contribution to the bookshelf of nuclear medicine or radiology clinics.
Cell therapy stem cells and regenerative medicine
Provides an overview of cell-based therapy for human diseases including the definition, history, and clinical applications of human stem cells and their use in regenerative medicine. It covers human pluripotent stem cells (human embryonic stem cells and human induced pluripotent stem cells), mesenchymal stem/stromal cells, and hematopoietic stem cells, bone marrow mononuclear cells. In terms of clinical applications, this book also provides an update on recent human trials using these cells to treat various diseases, including neurological disorders, pulmonary dysfunctions, metabolic/endocrine-related diseases, frailty, and cancer treatment. In addition, it discusses the authors’ clinical trial experiences related to these conditions in a clinical setting to provide additional insight into regenerative medicine, especially cell-based therapy.
British Media Coverage of the Press Reform Debate : Journalists Reporting Journalism
This book provides a detailed exploration of the British media coverage of the press reform debate that arose from the News of the World phone hacking scandal and the Leveson Inquiry. Gathering data from a content analysis of 870 news articles, Ogbebor shows how journalists cover debates on media policy and illustrates the impact of their coverage on democracy
Blind smart helmet
The Smart Helmet for the Blind is a project aimed at providing solutions for the challenges faced by blind individuals in their daily lives. The problem of detecting objects, identifying obstacles and distances, knowing the current location, and using a mobile application is a common issue for blind people. To address these problems, the Smart Helmet project was created, utilizing advanced technology and artificial intelligence to provide real-time assistance to the wearer. The helmet is connected to a Raspberry Pi 4, which processes information from the helmet's cameras and AI algorithms to analyze and predict the surrounding environment for a blind person.
Bioremediation of Soils Contaminated with Aromatic Compounds
Environmental biotechnology, which was in its infancy in the early 80's, has evolved thanks to the revolution brought about by molecular biology. Multiple successes in the biological cleanup of civil and industrial wastewater and of hydrocarbon soil pollution, demonstrate the vast power of clean technologies. In addition, the buildup of information on the activities of microorganisms as catalysts in all sorts of natural, industrial and animal environments has flourished. There is a continuing realization of the critical role of microbial processes in biological, industrial and geological systems. Since environmental biotechnology has matured, it is ready to tackle bigger challenges: the scaling up of many bioremediation systems still in progress, the search for novel biocatalysts for industrial applications, the continuing effort against common human life-threatening processes such as antibiotic resistance, the accumulation of hormone-mimicking substances (endocrine disrupters), the deposition of air-borne pesticides in the environment and, the degradation of recalcitrant contaminants. These endeavors will help prevent the contamination of food chains, protect human life and allow for human activity and economic development that do not compromise environmental sustainabijity.
Between Peace and Conflict in the East and the West : Studies on Transformation and Development in the OSCE Region
This book features various studies on democratization, transformation, socio-economic development, and security issues in the Organization for Security and Cooperation in Europe (OSCE) geographical region and beyond. Written by experts and scholars working in the field of human dimension, security, transformation and development in Europe and Asia, particularly in post-soviet and communist countries, it examines the connectivity that the OSCE provides between the East and the West.
Best of five MCQs for the endocrinology and diabetes SCE
Including questions based on the latest National Institute for Health & Care Excellence (NICE), Joint British Diabetes Societies (JBDS) & Endocrine Society clinical practice guidelines. Includes 20 more questions on diabetes to reflect the increased weighing given to this subject in the SCE exam. New tables and algorithms have been added to provide specialty trainees useful information relevant to clinical practice
Becoming citizens in a changing world : IEA international civic and citizenship education study 2016 International Report
Presents the results from the second cycle of the IEA International Civic and Citizenship Education Study (ICCS 2016). Using data from 24 countries in Asia, Europe and Latin America, the study investigates the ways in which young people are prepared to undertake their roles as citizens in a range of countries in the second decade of the 21st century. It also responds to the enduring and emerging challenges of educating young people in a world where contexts of democracy and civic participation continue to change. New developments of this kind include the increase in the use of social media by young people as a tool for civic engagement, growing concerns about global threats and sustainable development, as well as the role of schools in fostering peaceful ways of interaction between young people. Besides enabling the evaluation of a wide range of aspects of civic and citizenship education, including those related to recent developments in a number of countries, the inclusion of test and questionnaire material from the first cycle of the study in 2009 allows the results from ICCS 2016 to be used to examine changes in civic knowledge, attitudes and engagement over seven years.
Autoimmune Diseases in Endocrinology
Autoimmune Diseases in Endocrinology is a comprehensive and novel text that examines key features that predispose individuals to autoimmune diseases.
Asian century … on a knife-edge : A 360 degree analysis of Asia's recent economic development
This book delves into the widely held belief that the 21st century will be the "Asian Century" by examining the Asia's rapid economic development in the post-war era and the challenges it faces in forging ahead of world leaders in the West. The impact of the current turbulent global political climate on Asia is critically analyzed, employing a holistic and multidisciplinary approach, combining economic, social, political and geopolitical perspectives. Written in an accessible style, the book offers students, business, government, and civil society players powerful insights on Asia.
Artificial intelligence and national security
Analyses the implications of the technical, legal, ethical and privacy challenges as well as challenges for human rights and civil liberties regarding Artificial Intelligence (AI) and National Security. It also offers solutions that can be adopted to mitigate or eradicate these challenges wherever possible. As a general-purpose, dual-use technology, AI can be deployed for both good and evil. The use of AI is increasingly becoming of paramount importance to the governments mission to keep their nations safe. However, the design, development and use of AI for national security poses a wide range of legal, ethical, moral and privacy challenges. This book explores national security uses for Artificial Intelligence (AI) in Western Democracies and its malicious use. This book also investigates the legal, political, ethical, moral, privacy and human rights implications of the national security uses of AI in the aforementioned democracies. It illustrates how AI for national security purposes could threaten most individual fundamental rights, and how the use of AI in digital policing could undermine user human rights and privacy.
Aromatase Inhibitors
Many breast tumours are dependent upon oestrogen for their development and continued growth. Over the last 25 years hormone therapy has progressed from the irreversible destruction of endocrine glands to the use of drugs that reversibly suppress oestrogen synthesis or action. The inhibition of oestrogen synthesis is most readily achieved by inhibiting the final step in the pathway of oestrogen biosynthesis, the reaction which transforms androgens into oestrogens by creating an aromatic ring in the steroid molecule (hence the enzyme's trivial name, aromatase). Whereas the first aromatase inhibitors to be used therapeutically could be shown to produce drug-induced inhibition of the enzyme and therapeutic benefits in patients with breast cancer, they were not particularly potent and lacked specificity. However, second-generation drugs were developed and most recently third-generation inhibitors have evolved which possess remarkable specificity and potency. Initial results from clinical trials suggest that these agents will become the cornerstones of future endocrine therapy.
Aromatase Inhibitors
Many breast tumours are dependent upon oestrogen for their development and continued growth. Over the last 25 years hormone therapy has progressed from the irreversible destruction of endocrine glands to the use of drugs that reversibly suppress oestrogen synthesis or action. The inhibition of oestrogen synthesis is most readily achieved by inhibiting the final step in the pathway of oestrogen biosynthesis, the reaction which transforms androgens into oestrogens by creating an aromatic ring in the steroid molecule (hence the enzyme's trivial name, aromatase). Whereas the first aromatase inhibitors to be used therapeutically could be shown to produce drug-induced inhibition of the enzyme and therapeutic benefits in patients with breast cancer, they were not particularly potent and lacked specificity. However, second-generation drugs were developed and most recently third-generation inhibitors have evolved which possess remarkable specificity and potency. Initial results from clinical trials suggest that these agents will become the cornerstones of future endocrine therapy.
Argumentation in multi-agent systems ; Third International Workshop, ArgMAS 2006, Hakodate, Japan, May 8, 2006, revised selected and invited papers
Argumentation provides tools for designing, implementing and analyzing sophisticated forms of interaction among rational agents. It has made a solid contribution to the practice of multiagent dialogues. Application domains include: legal disputes, business negotiation, labor disputes, team formation, scientific inquiry, deliberative democracy, ontology reconciliation, risk analysis, scheduling, and logistics.
