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Cancer immunotherapy : Methods and protocols
Details multiple areas of new and emerging methods to develop the next generation of immunotherapy treatments. Chapters guide readers through analysis and characterisation of the interactions between tumour and immune cells, and cell engineering tools for cancer treatment, to provide a unique and compelling set of techniques instrumental to work with, and engineer, immune cells. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Cancer Chemoprevention ; Vol.2 : Strategies for Cancer Chemoprevention
In Cancer Chemoprevention, Volume 2: Strategies for Cancer Chemoprevention, leading chemopreventives investigators comprehensively describe the exciting methodologies that are accelerating progress in the chemoprevention field and review the state of clinical development of preventive agents in the major human cancer target organs. The authors provide sound guidelines for cancer chemopreventive drug development, detailing general strategies and methods for drug discovery, preclinical efficacy, characterization of precancers, safety evaluation of clinical cohorts, and clinical trial design.
Cancer cell biology : methods and protocols
Provides detailed methods on the mechanisms of underlying cancer cell biology. Chapters guide readers through techniques for culturing cancer cell lines, xenografts, cryopreservation of tumor cells, analyzing the co-culture of breast cancer cells, protein secretion by ELISA, flow cytometry-based, multi-parametric immunofluorescence analysis, protein expression by western blot, analysis of surface protein levels, protein recycling by biotinylation assay, and proteomics analysis by liquid chromatography-mass spectrometry.
Can We Talk? : Seven Principles for Managing Difficult Conversations at Work
This book offers guidance on how to create the right conditions for a meaningful discussion. The author identifies the seven key principles that enable both parties to gain a deeper understanding of what the other person may be thinking and will help establish their point of view more clearly: confidence, clarity, compassion, curiosity, compromise, credibility, courage.
Campbell biology; 12th ed.
Delivers a trusted, accurate, current, and pedagogically innovative experience that guides students to a true understanding of biology. The author team advances Neil Campbell's vision of meeting and equipping students at their individual skill levels by developing tools, visuals, resources, and activities that encourage participation and engage students in their learning. Known for strategically integrating text and artwork, this trusted course solution works hand in hand with Mastering Biology to reinforce key concepts, build scientific skills, and promote active learning.
Caesarean section delivery
It is the most common surgical operation performed in the world. Since first described 400 years ago, surgical rates continue to rise globally. Caesarean rates are now reported from South American countries of over 50% and rates of over 32% are currently being reported from the United States, China, England and Scotland. Surgical complications can occur at the time of operation and there are major implications for future pregnancies, including increased rates of placenta previa/accreta, stillbirth and preterm labour. This Element discusses many aspects of CD, including the Robson 10 group classification system, which classifies populations by characteristics such as parity, presentation of the fetus and the history of previous births, an evidencebased approach to surgical techniques, recommendations of the major guidelines and recommendations concerning trial of labour after previous caesarean.
CADD and informatics in drug discovery
Updates knowledge on recent advances in computational and bioinformatics tools/techniques and their practical applications in modern drug design and discovery programme. Also it encompasses fundamental principles, advanced methodologies and applications of various CADD approaches including several cutting-edge areas / presenting recent developments covering ongoing trends in the field of computer-aided drug discovery. Having contributions by a global team of experts, the book is expected to be an ideal resource for drug discovery scientists, medicinal chemists, pharmacologists, toxicologists, phytochemists, biochemists, biologists, RandD personnel, researchers, students, teachers and those working in the field of drug discovery. It will fill the knowledge gaps that exist in the current CADD approaches and methodologies/ protocols being widely used in both academic and research practices. Further, a special focus on current status of various computational drug design approaches (SBDD, LBDD, De-novo drug design, Pharmacophore-based search), bioinformatics tools and databases, computational screening and modeling of phytochemicals/natural products, artificial intelligence and machine learning, and network pharmacology and system biology would certainly guide researchers, students or readers to conduct their research in the emerging area(s) of interest. It is also expected to be highly beneficial to different stakeholders working in the pharmaceutical and biotechnology industries (RandD), the academic as well as research sectors. .
C# 10 Quick Syntax Reference : A Pocket Guide to the Language, APIs, and Library
Reviews the essential C# 10 and earlier syntax, not previously covered, in a well-organized format that can be used as a handy reference. Specifically, unions, generic attributes, CallerArgumentExpression, params span, Records, Init only setters, Top-level statements, Pattern matching enhancements, Native sized integers, Function pointers and more. You will: Employ nullable reference types / Work with ranges and indices / Apply recursive patterns to your applications / Use switch expressions
C# 10 in a Nutshell : The Definitive Reference
When you have questions about C# 10.0 or .NET 6, this guide has the answers you need. C# is a language of unusual flexibility and breadth, but with its continual growth, there's so much more to learn. In the tradition of O'Reilly's Nutshell guides, this thoroughly updated edition is simply the best one-volume reference to the C# language available today. Organized around concepts and use cases, this comprehensive and complete reference provides intermediate and advanced programmers with a concise map of C# and .NET that also plumbs significant depths
Business Writing For Dummies
This friendly guide equips you with a step-by-step method for planning what to say and how to say it in writing. This sytem empowers you to handle every writing challenge with confidence, from emails to proposals, reports to resumes, presentations to video scripts, blogs to social posts, websites to books. Discover down-to-earth techniques for sharpening your language and correcting your own writing problems. Learn how to adapt content, tone and style for each medium and audience. And learn to use every message you write to build better relationships and solve problems, while getting to the “yes” you want.
Business Resilience : A Practical Guide to Sustained Progress Delivered at Pace
Business Resilience is a practical guide to making organizations more resilient and improving current practices by building on what the organization does well. It explains how managers should constantly monitor their business environment and adapt their priorities depending on the level of disruption - from gradual innovation and improvement in good times to swarming on a single problem during a crisis.
Business process management Workshops ; BPM 2007 International Workshops, BPI, BPD, CBP, ProHealth, RefMod, semantics4ws, Brisbane, Australia, September 24, 2007, Revised Selected Papers
This book constitutes the thoroughly refereed post-workshop proceedings of 6 internationl workshops held in Brisbane, Australia, in conjunction with the 5th International Conference on Business Process Management, BPM 2007, in September 2007.
Business financial information secrets : How a business produces and utilizes critical financial information
Business Financial Information Secrets shows you how to produce, understand, and utilize financial information to the greatest effect for your business and the economy at large. This book guides you through the surprisingly clean and simple process of proper accounting and reporting, regardless of your organization’s size or structure. Cash flow and business capital management are covered extensively throughout the book as without a thorough understanding of these all-important concepts, you could be lacking critical information about the lifeline of your business.
Business continuity management : A practical guide to organizational resilience and ISO 22301
Business continuity management and resilience are critical to maintaining a healthy business, but many organizations either do nothing (leaving themselves exposed to disruption), take short cuts (leaving major gaps) or fail to properly engage senior stakeholders. This book is a straightforward guide to delivering an effective business continuity capability, including practical solutions built from the author's personal experience managing hundreds of projects in a variety of business settings.
Burning mouth disease : A guide to diagnosis and management
Gives a comprehensive overview of the symptoms, causes and treatment of Burning Mouth disease and Burning Mouth-like diseases.
Burning mouth disease : A guide for patients
Prepared for patients who suffer from 'Burning mouth disease', also referred to as 'Burning mouth syndrome'. It gives a comprehensive overview of the disease, its symptoms and management. Readers will learn about the terminology and definition of 'Burning mouth disease', and its suggested causes. Attention is paid to symptoms of various diseases that may mimic those of burning mouth disease. Neurological and psychogenic aspects are well covered, as are the many reported pharmacological and non-pharmacological treatment modalities.
Bulk Fill Resin Composites in Dentistry : A Clinical Guide
Dedicated to all relevant aspects of bulk fill materials and their uses in clinical practice. Today, we count over 30 different bulk fill materials, which can be used in the dental clinic. The composition of bulk fill materials and their different modes of application for moderate to large direct resin restorations placement are explained in this book. It is written by a group of international specialists and allows the reader to evaluate available materials, learn predictable techniques and evaluate long term survival as well as future developments. The book covers all fields related to the history of bulk fill composites, their composition and physical properties, and a step by step guide to their successful clinical applications.
Building XNA 2.0 Games : A Practical Guide for Independent Game Development
Building XNA 2.0 Games: A Practical Guide for Independent Game Development is written by James Silva, who recently won the prestigious Microsoft Dream Build Play game competition with his award–winning game, The Dishwasher: Dead Samurai. Building XNA 2.0 Games: A Practical Guide for Independent Game Development is an in–depth and exclusive look into the entire XNA game development process and includes the creation of a software game masterpiece. James Silva guides you through the process he took to build his award–winning title, from concept to reality. He reveals tips and techniques for creating a polished, high–quality game with very few resources, while bridging the gap between coding and art.
Building with infra-lightweight concrete : design, planning, construction
Infra-lightweight concrete combines the structural and thermal insulation functions of the building envelope in one monolithic material, thus providing new design options. The handbook is a practical guide to building with this new type of material.
Building to suit the climate : A handbook
Serves as a concrete aid to planning and design. With the planning process as its roadmap, it accompanies the planner from the basic evaluation stage through conception and implementation planning all the way to building operation. The building-related characteristics of the various climatic zones form the basis for the made-to-measure development of integrated building solutions. Well-conceived graphics illustrate planning contexts and facilitate efficient planning decisions and realistic predimensioning. Materials, systems, and technologies are described, and their areas of application are pointed out. Reference parameters, costs, and the presentation of interrelationships equip the planner to make a strategic and well-informed selection.
