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Abl Family Kinases in Development and Disease

Abl Family Kinases in Development and Disease provides an overview of the functions of Abl family kinases in Development and Disease. This new title discusses the biochemical, genetic, and cell biological data that elucidate the cellular roles for these kinases in these processes.

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Abiotic Stress Tolerance in Plants : Toward the Improvement of Global Environment and Food

Stresses in plants caused by salt, drought, temperature, oxygen, and toxic compounds are the principal reason for reduction in crop yield. For example, high salinity in soils accounts for large decline in the yield of a wide variety of crops world over; ~1000 million ha of land is affected by soil salinity. Increased sunlight leads to the generation of reactive oxygen species, which damage the plant cells. The threat of global environment change makes it increasingly demanding to generate crop plants that could withstand such harsh conditions. Much progress has been made in the identification and characterization of the mechanisms that allow plants to tolerate abiotic stresses.

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A Time for Metabolism and Hormones

Recent years have seen spectacular advances in the field of circadian biology. These have attracted the interest of researchers in many fields, including endocrinology, neurosciences, cancer, and behavior. By integrating a circadian view within the fields of endocrinology and metabolism, researchers will be able to reveal many, yet-unsuspected aspects of how organisms cope with changes in the environment and subsequent control of homeostasis. This field is opening new avenues in our understanding of metabolism and endocrinology. A panel of the most distinguished investigators in the field gathered together to discuss the present state and the future of the field. The editors trust that this volume will be of use to those colleagues who will be picking up the challenge to unravel how the circadian clock can be targeted for the future development of specific pharmacological strategies toward a number of pathologies.

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A Sea Change: The Exclusive Economic Zone and Governance Institutions for Living Marine Resources

A Sea Change in a Changing Sea The oceans, seas and coastal areas encompass over 70% of the earth’s surface. They are a critical driver of the earth’s hydrologic cycle and climate system, important for c- merce, transport, and tourism, a source of economically important living marine resources, minerals such as hydrocarbons, as well as new pharmaceutical compounds. The marine environment provides essential habitats for thousands of marine living 1 2 resources, which in turn contribute significantly to global food security, employment, 3 and trade. Overall, the sea’s contribution to human welfare, in terms of market and non-market resources and environmental services, has been estimated at US$21 trillion/year (Costanza, 2000). However, despite the importance of the ocean realm to humans, there is a growing sense that human impacts are destabilizing this system. Some experts believe that current fishing levels are approaching or exceeding the total 4 productivity of the ocean ecosystem (National Research Council, 1999).

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A Reappraisal of the Ascending Systems in Man, with Emphasis on the Medial Lemniscus

Based on material assembled by Dr Jaap HR Schoen who was one of the few neuroanatomists to apply the Nauta method to human material. Gaining insight in the consequences of longitudinal damage to the human spinal cord is necessary before reimplantation of the avulsed rootlets or an autologous transplant can be performed in man.

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A Legacy for Living Systems : Gregory Bateson as Precursor to Biosemiotics

This book represents a major attempt to revise this deficiency. Scholars from ecology, biochemistry, evolutionary biology, cognitive science, anthropology and philosophy discuss how Bateson's thinking might lead to a fruitful reframing of central problems in modern science. Most important perhaps, Bateson's bioanthropology is shown to play a key role in developing the set of ideas explored in the new field of biosemiotics. The idea that organismic life is indeed basically semiotic or communicative lies at the heart of the biosemiotic approach to the study of life.The only book of its kind, this volume provides a key resource for the quickly-growing substratum of scholars in the biosciences, philosophy and medicine who are seeking an elegant new approach to exploring highly complex systems.

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A History of Atmospheric CO2 and Its Effects on Plants, Animals, and Ecosystems

The authors address the future role of atmospheric CO2 and its likely effects on ecosystems. This book incorporates the advances of various earth science, environmental, and ecological fields into an overall account of global change and the changing dynamics of life on Earth.

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A Guide to Methods in the Biomedical Sciences

A Guide to Methods in the Biomedical Sciences gives a basic description of common methods used in research. This is not intended to be a methods book. Rather, it is intended to be a book that outlines the purpose of the methods described, their limitations and provide alternative approaches as appropriate. Thousands of methods have been developed in the various biomedical disciplines and those covered in this book represent the basic, essential and most widely used methods in several different disciplines. The historical background (including some interesting anecdotes) leading to the development of ground-breaking techniques are described, especially those that significantly advanced the field of biomedical research. Advances that earned their inventors prestigious Nobel Prizes are emphasized. The book is divided into six sections, highlighting selected methods in protein chemistry, nucleic acids, recombinant DNA technology (including forensic based methods), antibody-based techniques, microscopy and imaging, and the use of animals in biomedical sciences.

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A First Course in Statistics for Signal Analysis

This essentially self-contained, deliberately compact, and user-friendly textbook is designed for a first, one-semester course in statistical signal analysis for a broad audience of students in engineering and the physical sciences. The emphasis throughout is on fundamental concepts and relationships in the statistical theory of stationary random signals, explained in a concise, yet fairly rigorous presentation.

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A Dictionary of Biomedicine

A Dictionary of Biomedicine fills the need to define the specialist language used within an evolving field by offering clear, concise definitions of even the most complex biomedical terms. It includes more than 10,000 A-Z entries on all areas of biomedicine, such as genomics and biomedical science. Entries are authoritative and wide-ranging, covering terms from the related areas of anatomy, genetics, molecular bioscience, pathology, pharmacology, and clinical medicine.

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A Closer Look at Antibiotic Resistance

Bacterial infections have become more difficult, and sometimes impossible, to treat due to antibiotic resistance, which occurs when bacteria develop the ability to defeat the available drugs designed to kill them. According to the Centers for Disease Control and Prevention, each year, 2 million Americans become sick with antibiotic-resistant infections, and of that, about 23,000 die. This book examines the challenges related to antibiotic resistance, the development and use of diagnostic testing to identify antibiotic resistance, the development of treatments for resistant infections, and appropriate antibiotic use.

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A Changing World : Challenges for Landscape Research

"Written primarily for researchers and advanced students in environmental and social sciences, this latest book in Springer’s Landscape Series looks at some of the emerging fields and new challenges in landscape research. These include: the role of value systems in perceiving, appreciating, and managing landscapes / the ‘space’ and ‘place’ concept in landscape research GIS and remote sensing techniques for gathering and processing spatially and temporally explicit land cover, vegetation, and land use data / methods of landscape history / landscape genetics and genetic methods to test landscape connectivity and dispersal of plant and animal species"

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7th Asian-Pacific Conference on Medical and Biological Engineering : APCMBE 2008 22–25 April 2008 Beijing, China

Presents the proceedings of the 7th Asian-Pacific Conference on Medical and Biological Engineering (APCMBE 2008). Themed "Biomedical Engineering – Promoting Sustainable Development of Modern Medicine" the proceedings address a broad spectrum of topics from Bioengineering and Biomedicine.

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4th Kuala Lumpur International Conference on Biomedical Engineering 2008 ; BIOMED 2008 25–28 June 2008 Kuala Lumpur, Malaysia

The topics covered in the conference proceedings include: Artificial organs, bioengineering education, bionanotechnology, biosignal processing, bioinformatics, biomaterials, biomechanics, biomedical imaging, biomedical instrumentation, bioMEMS, clinical engineering, prosthetics.

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3rd Kuala Lumpur International Conference on Biomedical Engineering 2006 ; Biomed 2006, 11-14 December 2006, Kuala Lumpur, Malaysia

The Kuala Lumpur International Conference on Biomedical Engineering (Biomed 2006) was held from 11 to 14 December 2006 at the Palace of the Golden Horses, Kuala Lumpur, Malaysia. This international conference was jointly organised by the Department of Biomedical Engineering, University of Malaya, Malaysia; Department of Biomedical Engineering, Inje University, Korea; and Malaysian Society of Medical and Biological Engineering. The papers presented at Biomed 2006 cover the following areas: artificial intelligence, biological effects of non-ionising electromagnetic fields, biomaterials, biomechanics, biomedical sensors, biomedical signal analysis, biotechnology, clinical engineering, human performance engineering, imaging, medical informatics, medical instruments and devices, physiological modelling, simulation, and control, prostheses and artificial organs, regulations and organisations, rehabilitation engineering, telemedicine, tissue engineering, and virtual reality in medicine.

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3D Printing in Oral Health Science : Applications and Future Directions

Equips readers with a sound understanding of contemporary clinical applications in all fields of dentistry and their future directions. In the last few years, the development of 3D printing for medical and dental applications has increased tremendously. Advancements in 3D printing create the possibility of customized products, savings on small-scale productions, ease of sharing and processing of patient image data, and educational up-gradation. Looking at the dental specialties, it is evident that 3D printing has applications in all aspects of oral health science including prosthodontics, oral surgery, periodontics, endodontics, and orthodontics. This book will cover all major fields in dentistry and will help the practitioner in the process of decision-making and apply concepts in clinical or laboratory practice. It is based on current scientific evidence to provide readers with an up-to-date contemporary underst

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3D printing in oral & maxillofacial surgery

A comprehensive guide to 3D printing and 3D bioprinting methods and their application in oral and maxillofacial surgeries. Among the 3D printing methods considered are fused deposition modeling, selective laser sintering, photopolymer jetting, powder binder printing, and stereolithography, while the coverage of 3D bioprinting encompasses inkjet, microextrusion, and laser techniques. In each case, the relevance of the technique to oral and maxillofacial surgery is explained. In addition, the available inks and bioinks for 3D printing are reviewed. The roles of soft and hard tissue printing in oral and maxillofacial tissue engineering and the use of 3D printing in multi- and interfacial tissue engineering are then examined in depth. The particular value of 3D printing in the treatment of critically sized defects is discussed separately. Finally, up-to-date information is provided on guided tissue/bone regeneration using 3D printing. The book will be of interest to both oral and maxillofacial surgeons and biomedical engineers.

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3D cell culture : Methods and protocols

Expands on the previous edition with discussions about the latest organoid models developed for many more organs; new hydrogels and devices for 3D culture; and the organoid systems that have been improved by incorporating more components of tissue microenvironments in the in vitro culture. The chapters in this book are organized into five parts and cover topics such as biofabrication, organoids, microfluidic systems, bioprinting, and image analysis. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

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25 Years of P53 Research

Communication, awareness and access to information: Given the complexity of the field and the fact that data pertaining to each particular aspects of p53 biology or deregulation are scattered in many different publications, it is extremely difficult to access the full scale of relevant information of any specific p53-related topic. This book may help in this task by putting into perspective both general considerations on the p53 pathway and more specific information on various aspects of p53. In the longer term, however, open access to p53 complexity will require the development of knowledge bases accessible through the web and using simple navigation tools to guide users towards the specific information they need. Several efforts are currently being developed in that direction. They need to be strenghtened and better integrated within the rapidly growing galaxy of web-based information sources on molecular and individual variations in cancer. 2. Reference functional assays and structural analysis: Given the huge diversity of cellular and animal models for wild-type or mutant p53 functions, it will be important to set up standard, universally accepted assays to measure critical p53 protein functions.

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14th Nordic-Baltic conference on biomedical engineering and medical physics : NBC 2008 16–20 June 2008 Riga, Latvia

The topics covered by the Conference Proceedings include: Biomaterials and Tissue Engineering; Biomechanics, Artificial Organs, Implants and Rehabilitation; Biomedical Instrumentation and Measurements, Biosensors and Transducers; Biomedical Optics and Lasers; Healthcare Management, Education and Training; Information Technology to Health; Medical Imaging, Telemedicine and E-Health; Medical Physics; Micro and Nanoobjects, Nanostructured Systems, Biophysics

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