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National Institute of Allergy and Infectious Diseases, NIH ; Vol.1 : Frontiers in Research
National Institute of Allergy and Infectious Diseases, NIH: Volume 1, Frontiers in Research contains presentations given at the 2006 NIAID Research Conference held in Opatija, Croatia which brought internationally known researchers from the United States and Central and Eastern Europe to focus together on shared interests in microbiology, infectious disease, HIV/AIDS, and basic and clinical immunology. Some of the topics covered include emerging and re-emerging infections, the development of infectious disease prophylactics and therapeutics, drug resistance, and various topics in immunomodulation, autoimmunity, infections and immunity, and the development of vaccines.Extensive and in-depth, National Institute of Allergy and Infectious Diseases, NIH: Volume 1, Frontiers in Research is a valuable, comprehensive guide to the state of research today.
NASH and Nutritional Therapy
This collection of research and clinical findings on nonalcoholic steatchepatitis (NASH) and nutritional therapy contains significant new findings in several fields . As NASH frequently causes liver cirrhosis, the nutritional aspects of its treatment are discussed . Other areas covered include nonalcoholic fatty liver, the role of leptin in the pathogenesis of NASH, restricted diets and exercise therapy, mammalian targets of the peptide rapamycin, and genetic factors influencing the development of NASH.
Nanotechnology in endodontics : Current and potential clinical applications
Provides detailed information on the emerging applications of nanomaterials and nanoparticles within endodontics, highlighting the exciting potential clinical impact of nanotechnology in the field. The range of applications covered is diverse, encompassing drug and gene delivery, tissue engineering, antibacterial strategies, dentin tissue stabilization, dentin pulp regeneration and use in restorative and endodontic materials. Important scientific background information relating to each application is provided, with clear coverage of basic principles. In addition, potential pitfalls are identified and explained. The cytotoxicity of nanomaterials and nanoparticles is also addressed in a separate chapter. The book will be of value both for endodontic practitioners and for all scientists and graduate students who are interested in the application of nanotechnology in endodontics.
Nanotechnology and drug delivery : Principles and applications
Presents an overview of the rapidly developing field of nanotechnology applications in drug delivery systems and covers a variety of technologies and materials that help in achieving vast variation in the particle size needed in technology and drug delivery-based research. It discusses nanotechnology’s use in healthcare for the development of target-specific drug therapy and smart field systems and in the pharmaceutical industry to improve the quality, efficacy, and shelf life of medicines. Bringing together principles, theory, practice, and applications of nanotechnology.
Nanopharmaceuticals in regenerative medicine
A collective and comprehensive volume of the latest innovations in nanoscience technology for practical use in clinical, biomedicine and diagnostic arena. The term nanotechnology pops up in every segment of modern-day life. The primary aim of this book is to deliver the precise information to students, educators, technologists and researchers. A conglomerate of scientists from various research fields contributed to the chapters, giving detailed descriptions on the most recent developments of nanotechnology in the area of disease management. This book will also be useful for industrial research and development partners, start-up entrepreneurs, government policy makers and other professionals who are interested in nanomedicines.
Nanopharmaceuticals ; Vol.1 : Expectations and realities of multifunctional drug delivery systems
Reviews advances in the drug delivery field via nanovehicles or nanocarriers that offer benefits like targeted therapy and serves as a single dose magic bullet for multiple drug delivery with improved drug efficiency at a lower dose, transportation of the drug across physiological barriers as well as reduced drug-related toxicity. The chapters are written by a diverse group of international researchers from industry and academia. The series Expectations and Realities of Multifunctional Drug Delivery Systems examines the fabrication, optimization, biological aspects, regulatory and clinical success of wide range of drug delivery carriers. This series reviews multifunctionality and applications of drug delivery systems, industrial trends, regulatory challenges and in vivo success stories. Throughout the volumes discussions on diverse aspects of drug delivery carriers, such as clinical, engineering, and regulatory, facilitate insight sharing across expertise area and form a link for collaborations between industry-academic scientists and clinical researchers. Expectations and Realities of Multifunctional Drug Delivery Systems connects formulation scientists, regulatory experts, engineers, clinical experts and regulatory stake holders. The wide scope of the book ensures it as a valuable reference resource for researchers in both academia and the pharmaceutical industry who want to learn more about drug delivery systems.
Nanoparticle-Based Drug Delivery in Cancer Treatment
Discusses nanotechnological developments of interfering RNA-based nanoparticles, delivery vehicles, and validated therapeutic RNAi–molecular target interactions and explains the results of clinical and preclinical trials. The book also gives strategies for universal methods of constructing hybrid organic–inorganic nanomaterials that can be widely applied in the biomedical field. Focuses on : Recent advances of nanoparticle-mediated siRNA delivery systems and their application in clinical trials for cancer therapy Material platforms that establish NPs and both localized and controlled gene silencing The most promising systems for clinical application Surveys progress in nanoparticle-based nanomedicine in cancer treatment The most advanced of the nonviral nanocarriers for delivery of oligonucleotides to malignant blood cancer cells
Nanoparticle-based cancer vaccines
Reviews the fundamentals of cancer vaccines, explores the role of nanotechnology in improving vaccine design and delivery, and evaluates current clinical applications, challenges, and regulatory considerations, highlighting the potential of nanoparticle-based cancer vaccines in future cancer treatment.
Nanomedicine : Innovations, applications, and breakthroughs in the quest for health and medicine's future
Revolutionizing healthcare, by providing innovative solutions to some of the most challenging issues in medicine. This book provides an in-depth overview of nanoscale materials and devices that are advancing diagnostics, therapeutics, and personalized care in medical field. It focuses on nanomedicine’s impact on vaccine efficacy as well as innovative diagnosis and therapy for various type of cancer while addressing concerns about safety and toxicity. It examines how nanotechnology is enhancing drug delivery by precisely targeting medicines to specific cells or tissues, thereby increasing treatment efficacy with reduced side effects. Explores how nanoparticles are advancing medical imaging for earlier and more accurate disease detection, and how nanosensors allow real-time biomarker monitoring for faster and more reliable diagnoses. Additionally, it explores nanomedicine's role in managing cardiovascular diseases, improving bone health through nano-extracellular vesicles, and regenerative medicine, including ongoing clinical trials and ethical considerations.
Nanomaterials in dental medicine
Presents varied clinical applications of nanomaterials in dentistry ranging from diagnostics to therapeutics. it discusses role of nanomaterials in clinical applications and future needs. Contributors are international luminaries in their respective research area. The topics covered in this book are role of nanomaterials in oral and dental diagnosis, dental disease prevention, pain free dentistry, dental implantology. It also discusses the therapeutic applications of nanoparticles in oral cancer therapy. This book will be a valuable reference for researchers, clinicians, students and professionals working in the areas of nanotechnology and health sciences. It will also be of interest to the students and researchers primarily working in the field of materials science, applied chemistry, applied physics, and biotechnology.
Nanomaterials in clinical therapeutics : Synthesis and applications
Nanotechnology-based applications is a rapidly growing field encompassing a diverse range of disciplines that impact our daily lives. Nanotechnology is being used to carry out large-scale reactions in practically every field of biotechnology and healthcare. The incredible progress being made in these applications is particularly true for the healthcare sector, where they are used in cancer detection and treatment, medical implants, tissue engineering, and so forth. Expansions in this discipline are expected to continue in the future, resulting in the creation of a variety of life-saving medical technology and treatment procedures.
Myelodysplastic Syndromes
This book summarizes our current knowledge of MDS, from very basic aspects to the clinical management. It provides guidance to the diagnosis, an understanding of disease mechanisms, and a discussion of treatment strategies.
Musculoskeletal Tissue Regeneration: Biological Materials and Methods
Musculoskeletal Tissue Regeneration: Biological Materials and Methods aims to provide both basic and advanced knowledge of the newer methodologies being developed and introduced to the clinical arena.
Musculoskeletal Sonography : Technique, Anatomy, Semeiotics and Pathological Findings in Rheumatic Diseases
Ultrasonography is effective in the evaluation of joint involvement in patients with rheumatic diseases, and may be useful in diagnosis and in monitoring the synovial inflammation by power Doppler technique, with great sensitivity in comparison with clinical examination. The high-resolution US combined with power Doppler technique is also able to detect the peripheral entheseal abnormality, the bone erosion and the tendon involvement. The purpose of this book is to elucidate the examination technique, the sonographic changes in musculoskeletal rheumatic involvement and the ultrasound assessment of joint rheumatic diseases. The atlas is enriched with several figures, in which the US picture is compared with that of conventional radiography, CT and MRI.
Musculoskeletal Diseases 2021-2024 : Diagnostic Imaging
This book focuses on imaging of the musculoskeletal diseases. Over the last few years, there have been considerable advances in this area, driven by clinical as well as technological developments. The authors are all internationally renowned experts in their field. They are also excellent teachers, and provide didactically outstanding chapters. The book is disease-oriented and covers all relevant imaging modalities, with particular emphasis on magnetic resonance imaging. Important aspects of pediatric imaging are also included.
Multiple Sclerosis: Autoimmunity and Management
Multiple sclerosis (MS) is an immune-mediated inflammatory disease that attacks myelinated axons in the central nervous system, destroying the myelin and the axon in variable degrees and producing significant physical disability within 20–25 years in more than 30% of patients. The hallmark of MS is symptomatic episodes that occur months or years apart and affect different anatomic locations. Also, see the Autoimmune Disorders: Making Sense of Nonspecific Symptoms slideshow to help identify several diseases that can cause a variety of nonspecific symptoms. MS is diagnosed on the basis of clinical findings and supporting evidence from ancillary tests. Treatment consists of immunomodulatory therapy for the underlying immune disorder and management of symptoms, as well as nonpharmacologic treatments, such as physical and occupational therapy. Disease-modifying therapies have shown beneficial effects in patients with relapsing MS, including reduced frequency and severity of clinical attacks. These agents appear to slow the progression of disability and the reduce accumulation of lesions within the brain and spinal cord.
Multimodal Concepts for Integration of Cytotoxic Drugs
The first part of this book summarizes the rationale and the preclinical data for combined treatment with ionizing radiation and pharmaceutical agents. Individual chapters focus on different forms of combined treatment, with due consideration being given to a range of drugs and to emerging combinations with small molecules and antibodies, derived from recent advances in molecular oncology. The second part of the book comprises a series of disease-specific chapters in which the clinical results of combined modality treatment are presented. In addition, the topics of acute and late toxicity, supportive treatment and tolerance in elderly patients are reviewed.
Multifunctional Pharmaceutical Nanocarriers
Various pharmaceutical nanocarriers, such as nanospheres,nanocapsules, liposomes, micelles, cell ghosts, lipoproteins and some others are widely used for experimental (and already clinical) delivery of therapeutic and diagnostic agents. The use of nanoparticulate pharmaceutical carriers to enhance the in vivo efficiency of many drugs well established itself over the past decade both in pharmaceutical research and clinical setting.
Multidetector-Row CT Angiography
Multidetector-row CT has dramatically improved the results of computed tomography in all clinical applications, but its beneficial impact has been most striking in vascular imaging. The simplicity of acquisition and the wide availability of equipment make this modality especially suitable for routine clinical application. In this book the basic aspects of multidetector-row CT angiography are comprehensively reviewed. Individual chapters are included on technical principles, image processing techniques and contrast agent administration. All clinical applications are then discussed in depth, with lucid descriptions of the examination technique for particular clinical indications and of the findings that characterize specific diseases. Limitations and advantages in comparison with other imaging modalities are considered. A large number of high-quality black and white and color illustrations help to explain the clinical findings.
Multidetector-Row Computed Tomography : Scanning and Contrast Protocols
Multidetector-row computed tomography (MDCT) has advanced the approach to diagnostic assessment of many pathologies and now plays an integral role in imaging of both abdominal and cardiovascular diseases. The possibility to acquire diagnostic images with shorter scan duration, longer scan ranges, and/or thinner sections, MDCT has facilitated the opening of new horizons, such as interventional MDCT and functional imaging in stroke and oncology. In addition, advanced postprocessing techniques now permit high quality volumetric imaging in combination with maximum intensity projections, volume rendering, curved planar reformations and multiplanar reconstructions. This volume gathers contributions by internationally renowned specialists in the field who, through presenting their clinical experience, provide a thorough overview not only of MDCT and its practical applications, but also of workflow management in everyday clinical practice. Focussing on scanning and contrast protocols, the current advantages and disadvantages of non-enhanced vs. enhanced MDCT are discussed, along with insights into likely future developments. The volume represents an up-to-date source of technical and practically-oriented clinical information which should prove of great benefit to all who wish to improve or consolidate their knowledge and expertise in MDCT.
