Page 30
Page 30
Cell Cycle Regulation
The cell cycle is tightly regulated on many different levels to ensure properly controlled proliferation. Deregulation of cell cycle regulation is a hallmark of cancer. In this book, many aspects of cell cycle regulation are discussed, which include G1, S, M phase control, ubiquitin-mediated degradation, DNA damage response, mitotic spindle checkpoint, the centrosome cycle, Retinoblastoma protein family, the Myc oncogene, and mouse models for tumor suppressors, cyclin-dependent kinases, and meiosis. These chapters written by experts provide an updated view on how the cell cycle is regulated in vivo and about the involvement of cell cycle regulators in cancer.
CD4+CD25+ Regulatory T Cells : Origin, Function and Therapeutic Potential
CD4+CD25+ regulatory T cells (Treg) and interleukin-10 producing T regulatory 1 (Tr1) cells have been studied in most detail and are the subject of most articles in this issue. Treg, also called "natural" regulatory T cells, will be traced from their intra-thymic origin to the site of their action in peripheral lymphoid organs and tissues.
Casting : An Analytical Approach
For a long time, the die cast industry has used trial and error as a leading development method, resulting in tremendous growth in the utilisation of available CFD (computational fluid dynamics) software. This software allows the development of better products that maximise the advantages the die cast process has to offer. Casting: An Analytical Approach will refresh knowledge of the governing laws of the fluid dynamics that have an effect on die cast die and die cast process design. MATLAB® (MathWorks, Inc.) and Visual Basic® (Microsoft) code are listed in Casting: An Analytical Approach for every stage of product, die and die cast process design; providing better understanding of die and process design and simplifying calculations of the die cast die as well as the die cast process. Gas ventilation system calculations and fundamentals of compressible gas flow are also included.
Case studies in biocultural diversity from Southeast Asia : Traditional ecological calendars, Folk medicine and Folk names
This book demonstrates the linkages between local languages, traditional knowledge, and biodiversity at the landscape level in Asia, providing a fresh approach to discussions on Asia’s biocultural diversity. The book carries forward earlier analyses but importantly focuses on ‘traditional ecological calendars,’ ‘folk medicine,’ and ‘folk names’ in the context of the vital importance of maintaining biological, cultural, and linguistic diversity. It does this by addressing a range of cases and issues in relation to Southeast Asia: Brunei Darussalam, Indonesia, Malaysia, the Philippines, and North-East India. The several chapters demonstrate the ways in which the various forms of knowledge of the environment and its categorizations are important in areas such as landscape and resource management and conservation. They also demonstrate that environmental knowledge and the practical skills which accompany it are not necessarily widely shared. This book sends important messages to those who care about the sustainability of our environment, the maintenance of its biocultural diversity, or at least the maintenance of what remains of it because much has changed.
Carpal Tunnel Syndrome
This book is an instrument for deepening their knowledge of this condition and its management. It can be considered a moment for reflection on a condition that is erroneously considered simple to treat and easy to resolve. The surgical chapters compare various complications as well as various conservative and rehabilitative treatment options, thus underlining that this condition must not be underestimated. Incorrect treatment can have many negative ramifications: not only that the patient is dissatisfied but it can also lead to the hand’s functional loss and render the patient an invalid.
Care-Related Quality of Life in Old Age : Concepts, Models and Empirical Findings
Care-Related Quality of Life in Old Age explains the theory behind Care Keys, its methodology, empirical findings, and practical considerations in promoting effective, efficient elder care aimed at social and emotional well-being and including disabled and cognitively impaired patients.
Cardiovascular prevention and rehabilitation
Cardiovascular Prevention and Rehabilitation is a timely and thorough review of prevention, lifestyle counseling and rehabilitation for cardiologists and all physicians and other health professionals in cardiac rehabilitation teams. The Editors have gathered over 60 experts from all parts of the globe, each highlighting the role of cardiac rehabilitation and preventative cardiology from exercise testing and training, through nutrition, smoking cessation, behavioral and social support to adapted programs for newer groups with specific demands, such as the elderly, patients with implantable devices and patients after cardiac transplantation.
Capital project management ; Vol.2 : Capital project finance
Describes the strategic challenge of adding real economic value, properly and rigorously defined. The author explains how this is accomplished through the capital budgeting process; discusses the importance of free cash flow and finally, capital projects, as financial options, are discussed, as a way to manage risk while enhancing the likelihood of project approval.
Cancer Prevention
This volume contains the main proceedings of the fourth international conference on "Cancer Prevention 2006," which was held during February 16–18, 2006, in St. Gallen, Switzerland. Written by international experts in the field, the book comprises a comprehensive update on the most recent developments in the upsurging fields of molecular biology and cancer genetics and their interactions with clinical epidemiology and cancer prevention at various levels: genetic/biologic predisposition and definition of high-risk groups; preclinical models and tumor prevention; prospects of surrogate endpoints and biomarkers; progress in imaging and detection of neoplastic precursor lesions.
Cancer Metastasis and the Lymphovascular System : Basis for Rational Therapy
Sentinel lymph node (SLN) procedures have opened a window of opportunity for the study of micrometastasis. In eighty percent (80%) of metastasis there lies an orderly pattern of progression via the lymphatic network, while 20% of the time systemic metastasis occurs, bypassing the lymphatic system. During the past two decades, significant progress has been achieved in understanding the anatomical, functional, cellular and molecular aspects of the lymphovascular system and the metastasis process.Molecular imaging advances help to localize early cancers more precisely.
Cancer du sujet âgé = Cancer in the elderly
Etablir un diagnostic précoce, définir une stratégie adaptée et offrir une meilleure qualité de vie chez le sujet âgé atteint de cancer constituent les défis de l’Oncologie de ce début de siècle. Cet ouvrage a pour objectif de proposer aux médecins et aux étudiants un condensé des différents aspects de l’oncologie sur le sujet âgé. Dans une première partie, les aspects épidémiologiques et biologiques ainsi que l’évaluation gériatrique multiparamétrique sont abordés. Les particularités de l’application de la chimiothérapie, de la radiothérapie et de la chirurgie au sujet âgé sont passées en revue. Dans une troisième partie, la stratégie thérapeutique multidisciplinaire est ensuite détaillée par site.
Cancer drug resistance
In Cancer Drug Resistance, leading scientists from the best academic institutions and industrial laboratories summarize and synthesize the latest discoveries concerning the changes that occur in tumor cells as they develop resistance to a wide variety of anticancer therapeutics, as well as suggest new approaches to the biology of drug resistance that may afford new therapeutic opportunities.
Cancer cell biology : methods and protocols
Provides detailed methods on the mechanisms of underlying cancer cell biology. Chapters guide readers through techniques for culturing cancer cell lines, xenografts, cryopreservation of tumor cells, analyzing the co-culture of breast cancer cells, protein secretion by ELISA, flow cytometry-based, multi-parametric immunofluorescence analysis, protein expression by western blot, analysis of surface protein levels, protein recycling by biotinylation assay, and proteomics analysis by liquid chromatography-mass spectrometry.
Business trends in practice : The 25+ trends that are redefining organizations
In Business Trends in Practice: The 25+ Trends That Are Redefining Organizations, best-selling business author and strategist Bernard Marr breaks down the social and technological forces underlying these rapidly advancing changes and the impact of those changes on key industries.
Business modeling and software design ; 10th International Symposium, BMSD 2020, Berlin, Germany, July 6-8, 2020, Proceedings
This book constitutes the refereed proceedings of the 10th International Symposium on Business Modeling and Software Design, BMSD 2020, which took place in Berlin, Germany, in July 2020. BMSD is a leading international forum that brings together researchers and practitioners interested in business modeling and its relation to software design. Particular areas of interest are: Business Processes and Enterprise Engineering; Business Models and Requirements; Business Models and Services; Business Models and Software; Information Systems Architectures and Paradigms; Data Aspects in Business Modeling and Software Development; Blockchain-Based Business Models and Information Systems; IoT and Implications for Enterprise Information Systems.
Business Intelligence for the Real-Time Enterprises ; 1st International Workshop, BIRTE 2006, Seoul, Korea, September 11, 2006, Revised Selected Papers
The book includes different aspects in the lifecycle of business intelligence on very large enterprise-wide operational real-time data sets. In today’s competitive and highly dynamic environment, analyzing data to und- stand how the business is performing, to predict outcomes and trends, and to improve the effectiveness of business processes underlying business operations has become critical. The traditional approach to reporting is not longer adequate; users now - mand easy-to-use intelligent platforms and applications capable of analyzing real-time business data to provide insight and actionable information at the right time. The end goal is to improve the enterprise performance by better and timelier decision making, enabled by the availability of up-to-date, high-quality information.
Business Ethics : The Ethical Revolution of Minority Shareholders
The empirical part of the book presents four cases of US, French and Israeli companies, most of them in high-tech, in which the minority shareholders lose almost all of their investments. The cases are based on current events and try to find the common aspects and basic rules that govern the wrongdoing to minority shareholders.The book concludes that once the minority shareholders, who are ultimately all of us, are assisted by the new vehicles of Ethics, and are properly organized, motivated and conscious of their strengths, they will be able to win their fight and safeguard their interests.
Business criminal law: A primer for management and economics
Deals with business criminal law from the perspective of Germany, Austria, Liechtenstein and Switzerland. It primarily addresses students in business and economics (master's programme) as well as business practitioners, but is also meant for lawyers and law students. As criminal law legislators exert considerable influence on economic life, raising and growing awareness in the area of criminal law seems compulsory for future managers and executives. This textbook approaches the legal field less normatively and rather in a practical and entrepreneurial way. Its contents are based on the master level class "Business Criminal Law
Business continuity management : A practical guide to organizational resilience and ISO 22301
Business continuity management and resilience are critical to maintaining a healthy business, but many organizations either do nothing (leaving themselves exposed to disruption), take short cuts (leaving major gaps) or fail to properly engage senior stakeholders. This book is a straightforward guide to delivering an effective business continuity capability, including practical solutions built from the author's personal experience managing hundreds of projects in a variety of business settings.
Buried Waste in the Seabed – Acoustic Imaging and Bio-Toxicity : Results from the European SITAR Project
Buried waste on the seabed is a major source of pollution. But, very often, waste sites are not known until a serious problem occurs, or are not adequately mapped. Recent examples around Europe include WWI and WWII ammunition dump sites (e.g. Beufort Dyke in the UK), dumped nuclear submarines in the Arctic Seas, clandestine or hidden toxic-waste in the Baltic Sea and the North Sea.. Even if properly documented, waste sites evolve with time (dumped material can move with currents and tides, especially on a scale of decades; toxic-material barrels can corrode and leak). This book shows the results of a concerted EU-funded effort to tackle this problem and find innovative ways to identify and map toxic waste sites ona the seabed, whether they have been covered with sediments or not. These results are applicable to any region on the seabed in the entire world.
