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Chemical and functional properties of food components
Described the contents of food raw materials and products, the chemistry/biochemistry of food components, as well as the changes occurring during post-harvest storage and processing affecting the quality of foods. Discusses the role of chemical compounds in the structure of raw materials and the formation of different attributes of food quality, including nutritional value, safety, and sensory properties. It contains four new chapters: “Non-Protein Nitrogenous Compounds”; “Prooxidants and Antioxidants in Food”; “Non-Nutritive Bioactive Compounds in Food of Plant Origin”; and “Analytical Methods Used for Assessing the Quality of Food Products.”
Cereals and millets
Genome Mapping and Molecular Breeding in Plants presents the current status of the elucidation and improvement of plant genomes of economic interest. The focus is on genetic and physical mapping, positioning, cloning, monitoring of desirable genes by molecular breeding and the most recent advances in genomics. The series comprises seven volumes: Cereals and Millets; Oilseeds; Pulses, Sugar and Tuber Crops; Fruits and Nuts; Vegetables; Technical Crops; and Forest Trees.
Cell-secreted vesicles : Methods and protocols
Pesents hands-on technological protocols used to target an array of cell-secreted extracellular vesicles (EVs) in a variety of biological systems. Beginning with methods for EV purification and analysis, the book continues with sections on the study of EV functions as well as specific systems and models allowing for the study of EVs of different origin. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Cell-Cycle Mechanisms and Neuronal Cell Death
This book serves to gain new insights into the molecular determinants of neuronal death and to establish new targets for therapeutic intervention.
Cell Motility in Cancer Invasion and Metastasis
Cancer Morbidity and mortality result from invasive and metastatic spread. Currently, no therapies are aimed at the underlying mechanisms that enable this progression due to only nascent recognition of the distinct biology which occurs only during tumor dissemination. Recent advances have highlighted the central role of cell motility during the dynamic and transient process of tumor invasion and metastasis. This book includes state-of-the-art updates by international leaders in these studies. Chapters first present the novel model systems that enable new investigations and insights. Chapters then describe in depth the key processes and molecules that may be therapeutically targeted. Finally, the role of cell motility and its signals is explored in a number of key tumor types. This compilation should be useful to researchers in basic and translational oncology as well as those developing novel agents to prevent tumor invasion and metastasis.
Cataract and refractive surgery
The second volume of "Cataract and Refractive Surgery" in the Essentials in Ophthalmology series provides new information on cataract and refractive surgery. This book will help clinicians provide the best results for their cataract and refractive surgical patients and is also indispensable for continuous education and advanced training.
Cataract and refractive surgery
Te series Essentials in Ophthalmology was initi- to discuss clinically relevant and appropriate t- ated two years ago to expedite the timely trans- ics. Summaries of clinically relevant information fer of new information in vision science and have been provided throughout each chapter. evidence-based medicine into clinical practice. Each subspecialty area now has been covered.
Catalytic role of amino acids in organic reactions
Asymmetric organometallic and organocatalytic processes have attracted great interest. Asymmetric synthesis using both natural and unnatural amino acids has been tremendously important from synthetic as well as industrial viewpoints, and numerous new methodologies have been developed in the last decades. Herein we provide an overview of old and very recent (since 1900 till now) advances and applications in the area of heterogeneous catalysis, homogeneous catalysis, electrocatalysis, photocatalysis, organocatalysis, thermal catalysis using amino acids [proline, glycine, alanine, valine, serine, threonine, cysteine, methionine, asparagine, glutamine, lysine, arginine, histidine, aspartate, glutamate, phenylalanine, and tryptophan], (supported or unsupported), an amino acid containing materials or amino acids derivatives as an essential component of catalysts, this book highlights the most important and recent developments to immobilize or support amino acids on various support materials. This book is suitable as supplementary reading for courses targeting the design, synthesis, and application of chiral catalysts, asymmetric catalysis, and sustainable production.
Cardiovascular MRI in practice : A teaching file approach
This text resource outlines the systematic approach to CMR interpretation. The depiction of a "core exam" and the modifications used for a variety of patient circumstances are demonstrated using simple visual assessment of the images. Special emphasis on the advantages of CMR relative to other modalities reinforces practical learning objectives, organized so that the reader starts with patient images – as one would in a clinical scenario – and works back to the didactic material.
Cardiovascular MRI : 150 Multiple Choice Questions and Answers
A Practical Guide for Cardiovascular Magnetic Resonance Imaging provides a comprehensive and reader-friendly educational tool for physicians starting to work with CMR and cardiology and radiology trainees preparing for the Board certification examination.
Cardiac Mechanotransduction
For about hundred years the investigation of heart physiology has had one central guiding principle, the "law" of Frank and Starling. This connects the return of blood into the heart and the blood pressure with cardiac con traction force. The "law" does it in a way that enables the cardiovascular system to react to perturbations without major malfunctions. This book is a compilation of reviews of prominent scientists on this subject. The differ ence of the original formulation of the Frank-Starling principle is that mechanotransduction is the central theme that leads the reader through the book. Since the discovery of the "law" the scope of topics related to this subject has broadened enormously, as can be seen easily by glancing at the contents of this book. Mechanotransduction in the heart has many faces that range from molecules to humans and their diseases.
Cardiac drug therapy
Cardiac Drug Therapy, 7th ed., addresses the pharmacology and therapeutic application of drugs used to treat heart diseases and hypertension. Additions and updates to the sixth edition include six new chapters on current controversies in cardiac drug therapy such as the beta blocker issue many cardiologists are presently grappling with. The book provides practical advice on how to manage cardiac diseases and addresses the choice of one particular cardiac agent vs. another. In addition to providing core knowledge in cardiovascular therapeutics, the text assists in resolving some of the issues surrounding cardiac drugs. Cardiac Drug Therapy provides practical information including properties, dosage, side effects, potential salutary benefits, and drawbacks on virtually all commercially available cardiac drugs.
Carbon-based nanocarriers for drug delivery
Carbon-Based Nanocarriers for Drug Delivery enlists the latitudes and advancements in the synthesis processes, functionalization, and applications of carbon-based nanomaterials (CBNs) in targeted drug delivery systems (DDSs). It covers the applicability and suitability of CBNs as nanocarriers for efficient drug delivery application via elucidating the recent advancements in CBNs, their functionalized and innovative derivatives, and the relevant case studies. The book explores the necessity, efficacy, toxicological aspects, and challenges for the application of CBN in targeted DDSs.
Cancerimmunotherapies : Solid tumors and hematologic malignancies
Presents the clinical scope of cancer immunotherapeutic agents for solid tumors and Hematologic malignancies, elaborates on the scientific details of their modes of action, and presents the impact of these agents on oncology, patients and the broader healthcare system. At present, cancer immunotherapies fall broadly into three categories: immune checkpoint inhibitors (ICIs), adoptive T cell therapies, and cancer vaccines which have distinct mechanisms of action. Immune checkpoint inhibitors rely upon disrupting tumor antigen recognition as self by the immune system through inhibition of checkpoint molecules. Adoptive T cell therapies involve the engineering of T cells ex vivo to target and destroy tumor cells. The first part of this book will provide an overview of the discovery and mechanistic details of the technology. The second part will be devoted to elaborating on the clinical outcomes, successes and limitations for specific tumor subtypes, which includes both solid tumors and hematologic malignances for both pediatric and adult populations.
Cancer Proteomics : From Bench to Bedside
the authors collectively provide the current status of proteomics in cancer therapy and offers the existing technologies used in proteomics that allow for protein profiling and for the identification of druggable targets in human samples. Mass spectrometry based protein characterization and protein microarrays hold great promise of predicting response to specific drugs in cancer therapy. Insightful to the reader with broad perspectives on topics related to the use of proteomic strategies in cancer therapy, Cancer Proteomics offers anticipated challenges that may arise from its application in daily practice.
Cancer Gene Therapy
the authors comprehensively review the anticancer genes and gene delivery methods currently available for cancer gene therapy, including the transfer of genetic material into the cancer cells, stimulation of the immune system to recognize and eliminate cancer cells, and the targeting of the nonmalignant stromal cells that support their growth. They also thoroughly examine the advantages and limitations of the different therapies and detail strategies to overcome obstacles to their clinical implementation
Cancer du sein avancé : 29es Journées de la Société Française de Sénologie et Pathologie Mammaire (SFSPM) Avignon, 14–16 novembre 2007 = Advanced breast cancer : 29th Days of the French Society of Senology and Breast Pathology (SFSPM) Avignon, November 14–16, 2007
These days are an opportunity to remind and persuade those less convinced that the treatment of this very particular phase of the disease is not limited to a score played by a few speakers or even by medical oncologists alone; but on the contrary, we must bring into play a truly philharmonic polyphonic ensemble, united around the patient and comprising all the players in multidisciplinary care: general practitioner, surgeon, radiotherapist, imaging specialist, gynecologist, general practitioner, psychologist, algologist, supportive care workers ...
Cancer drug resistance : methods and protocols
Discusses the latest techniques used to identify cancer drug resistance determinants at the molecular, cellular, and functional levels. Chapters in this book cover up-to-date topics including tumor-microenvironment cell co-culture methods and microfluidics systems; workflows for functional assessment of drug resistance in vitro and in vivo; quantitative techniques for identifying quiescent blood-flow circulating cells; and single-cell characterization methods, such as mass cytometry.
Cancer Chemoprevention ; Vol.2 : Strategies for Cancer Chemoprevention
In Cancer Chemoprevention, Volume 2: Strategies for Cancer Chemoprevention, leading chemopreventives investigators comprehensively describe the exciting methodologies that are accelerating progress in the chemoprevention field and review the state of clinical development of preventive agents in the major human cancer target organs. The authors provide sound guidelines for cancer chemopreventive drug development, detailing general strategies and methods for drug discovery, preclinical efficacy, characterization of precancers, safety evaluation of clinical cohorts, and clinical trial design.
Cancer : Cell Structures, Carcinogens and Genomic Instability
Tumors can be induced by a variety of physical and chemical carcinogens. The resulting tumor cells are usually abnormal in their morphology and behavior and transmit their abnormalities to their daughter tumor cells. Most theories of the pathogenesis of tumors suggest that carcinogens in some way cause alterations either of the genomes or of inheritable patterns of gene expression in normal cells, which then cause morphological and behavioral changes. This volume presents a collection of articles aimed at the question by what genetic or epigenetic mechanisms carcinogens can cause morphological abnormalities of tumor cells. It includes reviews of cellular targets of known carcinogens, and presents varying viewpoints of how morphological abnormalities and the actions of carcinogens might be related.
