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Les infections intra-abdominales aiguës = Acute intra-abdominal infections

Paradoxically, serious intra-abdominal infections are the forgotten ones in the world of infectious diseases. Paradoxical, because they are very common pathologies, affecting all age groups of the population and often life-threatening; paradoxical, because they concern many medical specialties through intensive care, gastroenterology, hepatology, imaging, infectious diseases, emergencies and surgery. Hence the need, thanks to an interdisciplinary collaboration, to publish a book in French bringing together all infectious abdominal pathologies, thus offering a synthesis of recent data from the literature in this field. This document should allow the various specialties concerned to find updates integrating the latest clinical, diagnostic and therapeutic data. Specialty interns and practitioners in the field will find something to establish an effective and up-to-date strategy for the management of patients with these pathologies, the high incidence of which and the severity of which is too often overlooked, it is important to remember.

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Les fonctions sphinctériennes = Sphincter functions

This book on Sphincter functions provides an update on a very topical subject, urinary and anal incontinence. Divided into three parts, it first deals with fundamental aspects, whether anatomical, physiological or clinical. The explorations of the various urinary and anorectal functions are described with electrophysiological, manometric, urodynamic tests as well as imaging. The second part is devoted to the pathology with all the dysfunctions that we encounter in daily practice. Urinary and anal incontinence, dysuria and retention, neurological sphincter disorders, dysfunctions in pregnant women and children are discussed. The last part takes stock of treatments, whether pharmacological, rehabilitative or surgical. This work, which contains a considerable amount of information, will undoubtedly be of interest to many medical specialists (physicians in physical medicine and rehabilitation, neurologists, gastroenterologists, gynecologists, general practitioners, pediatricians), surgeons (urologists, gynecological surgeons, surgeons). digestive) whether they are in training or already involved in the management of perineal disability. Other health professionals will find reference material there (nurses, physiotherapists, midwives).

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Les cancers ovariens = Ovarian cancers

Deals with ovarian cancers and their therapeutic management. Besides the epithelial tumors which are the most frequent, the rarer tumors, with attenuated malignancy, germ cells or of the ovarian stroma are also studied. Specialists from multiple backgrounds each deliver in their field the most recent knowledge on the fundamental aspects of the disease, its genetic, epidemiological and prognostic characteristics and its pathological peculiarities. Modern means of diagnosis are presented. The surgical technique, including laparoscopy, is detailed at the different stages of the disease. The therapeutic strategy aims to position the surgery and chemotherapy according to the stage. The current place of radiotherapy and isotopic therapies is indicated. Some more specific aspects are discussed, screening, lymph node dissection, the “second look”, intraperitoneal chemotherapy with or without hyperthermia, treatment of the elderly, monitoring after treatment… as well as the emergence of targeted therapies.

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Les cancers digestifs = Digestive cancers

Digestive tumors are among the most common malignant tumors and represent a major public health problem. This is one of the areas that has evolved the most in recent years in oncology due to significant progress in diagnostic strategies and therapeutic management. It seems essential that this progress be implemented in the daily practice of physicians treating these tumors. This book, the result of multidisciplinary work, provides a practical and up-to-date approach to the management of malignant digestive tumors. The first chapters are devoted to general and original subjects such as epidemiology, genetics, the management of elderly subjects. A second part approaches in a pragmatic and practical way the principles of diagnostic and therapeutic management by localization. A third part, devoted to the practical realization of chemotherapy, takes stock of new therapeutic approaches, oral or locoregional chemotherapy. Finally, the last part of the book is dedicated to digestive cancer emergencies and the palliative management of these tumors.

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Leptomeningeal Metastases

Leptomeningeal Metastases provides the reader with an overview of the state-of-the-art therapy for the leptomeningeal patient with additional information on epidemiology, symptom management, new clinical trials, and current basic research in animal models for experimental therapies. "Leptomeningeal metastases remains a devastating manifestation of hematologic malignancies and solid tumors. Leading figures in the field review the pathophysiology and clinical consequences of this process. State-of-the-art treatment strategies are presented highlighting advances in current management."

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Lentil : An ancient crop for modern times

Presents the most comprehensive and up to date review of research on lentil production systems, biotic and abiotic stresses management, quality seed production, storage techniques and lentil growing around the world. This book will be of great value to legume breeders, scientists, nutritionists, academic

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Lehninger Principles of Biochemistry

Help students navigate the complex discipline of biochemistry with a clear and coherent presentation. Renowned authors David Nelson, Michael Cox, and new co-author Aaron Hoskins have focused this eighth edition around the fundamental principles to help students understand and navigate the most important aspects of biochemistry. Text features and digital resources in the new Achieve platform emphasize this focus on the principles, while coverage of recent discoveries and the most up-to-date research provide fascinating context for learning the dynamic discipline of biochemistry.

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Left-right asymmetry in vertebrate development

A host of studies has unravelled the involvement of many genes in the left right patterning pathway. Based on this knowledge the genetic basis of human laterality defects are beginning to be revealed. It is a major challenge now to understand how all these genes control left right development as well as the complex set of interactions established between them.

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Learning Surgery : The Surgery Clerkship Manual

Provides a ready reference to those in third and fourth year residencies. Essential algorithms and case presentations meet with clerkship learning objectives as outlined by the Association of Surgical Education in their ASE Manual. Two sections include Introduction to Clinical Surgery in the Surgical Clerkship Setting and Management of Surgical Diseases During the Clerkship. Chapters include: Stroke, Hypertension, Abdominal Masses, Head Injuries, and Burns. Written by leading clinicians and educators, both surgery residents and medical students will find LEARNING SURGERY indispensible in their rotations and clerkships. Surgeons who train residents will also find the text a valuable ajunct to their teaching.

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Learning Diagnostic Imaging : 100 Essential Cases

Intended to provide medical students, residents of Radiology, and anybody else beginning to be involved in the radiological world, with a useful tool that gives them a quick and comprehensive overview of Radiology.

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Le dépistage du cancer du sein : un enjeu de santé publique = Breast cancer screening: a public health issue

Fifteen years after the first experiments, the breast cancer screening program was rolled out in France in 2004. It is aimed at more than eight million women aged 50 to 74. Public health action on such a scale is exemplary in Europe and especially in France where the health system is not centralized. The new edition of this book takes stock of the current state of the program and its initial results. It updates technical and radiological aspects, assessment indicators, communication and forensic problems and finally the progress of foreign programs. The history of the French program is detailed from the 1990s until 2006, with the publication of the latest version of the specifications by the Directorate General of Health. The short and medium term objectives are re-specified: to increase the participation of women, to retain them and to further improve the quality of practices. The challenge is to combine the performance of screening and therapeutic management to finally achieve a clear reduction in mortality, which has remained stable for twenty years.

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Le dépistage du cancer du col de lutérus = Cervical cancer screening

Each year, cervical cancer kills approximately 1,000 people in France, making it the fifth leading cause of cancer death and the eighth most common cancer among women. While eradicating cervical cancer is not possible, a national screening campaign should significantly reduce its incidence. This campaign should be based, in particular, on the systematic use of Pap smears. Conventional Pap smears have already reduced the number of invasive cancers by more than 50%. Improving them requires optimizing their sensitivity. This book details the natural history of cervical cancer, its incidence and mortality, and the various aspects of screening: general principles, the French screening program, the different types of Pap smears, the role and contribution of the HPV test, the management of abnormal Pap smears, the role of colposcopy, and the follow-up of treated women. It is intended for all those involved in this screening : specialist interns and gynecologists, pathologists and biologists, public health physicians, but also general practitioners whose role in screening is privileged since they are at the forefront of medical demand.

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Le dépistage du cancer colorectal : État des lieux et perspectives = Colorectal cancer screening: Current status and perspectives

Prevention and screening are two major challenges for Public Health to reduce cancer mortality in our country. Screening for colorectal cancer is therefore quite exemplary. The number one cancer in both sexes in France, its incidence continues to increase due to the aging of the population. Its mortality remains high, in the order of fifty percent, despite the major therapeutic advances made in recent years. Preceded by a precancerous lesion - the adenomatous polyp, which can be removed by colonoscopy - colorectal cancer is also curable at the early stage. Finally, it can be the subject of a screening strategy, the impact of which has been demonstrated today on the reduction in mortality, when it is detected before any symptom by a simple test for blood in the stool followed by , in case of positivity, by a total colonoscopy. This book takes stock of the scientific rationale and the state of play of organized colorectal cancer screening in France. It is also an opportunity to discuss emerging techniques and strategies that can help improve the results of this screening if they prove their superiority over the current strategy. Intended primarily for doctors, this book is also intended for healthcare professionals and all those who, concerned about their health, have a proactive attitude in terms of screening and preventing this cancer.

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Le dépistage du cancer bronchique : De l'espoir à la réalité = Lung cancer screening : From hope to reality

An ambitious program has been launched in terms of research, diagnosis, prevention, and screening. Among cancers, the leading cause of cancer death is lung cancer. This disease, so closely linked to behavioral habits, both focuses and encapsulates the problem. Despite constant progress in treatment, the prognosis remains bleak, explaining the fatalistic impression left by the last decade. While significant efforts were being made in screening for other cancer sites, lung cancer remained in the shadows, with studies showing limited effectiveness in this approach. The advent of spiral CT scanning has revolutionized the field, giving rise to new hope alongside anti-smoking campaigns. Autofluorescence endoscopy, by enabling the diagnosis of pre-neoplastic lesions, completes an arsenal that finally allows us to envision an effective, combined strategy. This book brings together all the elements relating to screening and early diagnosis. The road from hope to reality is long, but we must acknowledge that, for the first time, we know it exists.

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Le cancer du sein = Breast cancer

The reader will find there both a synthetic summary of the current state of knowledge of epidemiology, risk factors and pathological aspects as well as a presentation of the surgical aspects, in particular, of the new approach that constitutes the sentinel node procedure. Radiotherapy, in a practical view, is divided into essential clinical questions. The medical treatment is then discussed according to the different situations encountered on a daily basis. Particular attention is of course paid to recent data both with the contribution of hormone therapy and targeted therapies. Finally, the symptomatic treatments and especially the psychological care of these patients are not forgotten.

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Le Cancer du rein = Kidney cancer

Localized tumors are discovered at an earlier stage. The concept of active surveillance emerges. Minimally invasive treatments such as cryotherapy or radiofrequency for selected cases are now available. The indications for elective open partial nephrectomy are expanding and laparoscopic and then robotic partial nephrectomy are being evaluated.

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Late Effects of Cancer Treatment on Normal Tissues

Based on the LENT V NCI-sponsored meeting held in May 2004 and the CURED I conference held in 2006. It addresses a number of critical topics relating to late effects, such as mechanisms of injury, the role of screening, options for interventions, second malignancies, and prevention.

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Lapproccio e la gestione per processi in pneumologia = The process-based approach and management in pulmonology

The topics covered are highly relevant to the application of the methods and tools outlined in quality improvement programs. This is in an effort to enhance the specific skills of the pulmonologist, thus making him an effective and independent liaison with the relevant strategic management. With great sensitivity, the SIMeR (Italian Society of Respiratory Medicine) has chosen to sponsor this edition, the only one to date in the field of Pulmonology, whose contents are based on the proposals and work of the leaders of one of its most recently established Study Groups, the "Continuous Quality Improvement in Pulmonology" Study Group.

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Landscapes, Genomics and Transgenic Conifers

What is the future of genetically modified (or transgenic) conifer plantations? The content of this edited volume Landscapes, Genomics and Transgenic Conifers addresses this question directly - and indirectly - using language drawn from policy, forest history, genomics, metabolism, pollen dispersal and gene flow, landscape ecology, evolution, economics, technology transfer and regulatory oversight. Although the book takes its title from a Nicholas School Leadership forum held November 17-19, 2004 at Duke University, its de novo contents move past the forum’s deliberations. The result is a trans-disciplinary book composed of 14 chapters written by a total of 31 authors working in North America, South America, Europe and Africa.

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Landscape Pattern Analysis for Assessing Ecosystem Condition

Landscape Pattern Analysis for Assessing Ecosystem Condition presents a new method for assessing spatial pattern in raster land cover maps based on satellite imagery in a way that incorporates multiple pixel resolutions. This is combined with more conventional single-resolution measurements of spatial pattern and simple non-spatial land cover proportions to assess predictability of both surface water quality and ecological integrity within watersheds of the state of Pennsylvania (USA).

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