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Basis and Treatment of Cardiac Arrhythmias
Incorporating the information related to mechanisms and treatment of cardiac arrhythmia, this book discusses genetics of arrhythmias, cell signalling molecules as potential therapeutic targets and trafficking to the membrane. These approaches and implementations of anti-arrhythmic therapy derive from many decades of research.
Basic Science Techniques in Clinical Practice
Medical researchers including doctors, nurses, medical students and allied health professionals are required to undertake a period of research as part of their career pathway. Basic Science Techniques in Clinical Practice covers the main areas, allowing anyone to set up and complete research projects and this information can easily be translated to clinical projects. Written by international authors to provide a flavor from many institutions, the book’s appeal is cross-sectional, both at hospital and primary care levels worldwide.
Basic methods for the biochemical lab
Covers : quantitative methods (proteins, nucleic acids, phospholipids and carbohydrates), electrophoresis (several polyacrylamide and agarose systems, 2D-PAGE, detection methods and affinity electrophoresis), chromatographic protocols (thin-layer chromatography, GPC, IEC, affinity chromatography, HPLC), immunochemical protocols (hapten-carrier and enzyme conjugation, immunization and antibody purification, immune affinity chromatography, ELISA), centrifugation (differential and density gradient centrifugation for cells and cellular fractions), radioactivity (labeling and counting), buffers (buffer properties and compositions).
Basic methods and protocols on Sourdough
Details traditional and modern approaches to characterize sourdough and to monitor its features during production, propagation and use, through state-of- the art analytical tools. Chapters guide reader through procedures to prepare and propagate the mature sourdough, to analyse and monitor microbiological, biochemical and rheology features of sourdough, sensory, and nutritional attributes of baked goods. Written in the format of the Methods and Protocols in Food Science series, chapters list necessary materials and methods for readily reproducible protocols.
Basic knowledge of pharmacology
Concise and up-to-date coverage of the most important drugs Integration of experimental and clinical pharmacology with focus on diseases Discusses the most important drugs (400) in the context of relevant diseases. Summary tables and schemes, MCQ exam questions, case studies and a list of drugs aid memorization of the material before an exam. All chapters are written in the same concise style and use a modern and precise pharmacological nomenclature. After reading of the book, the student will be able to critically assess the proper use of the most important drugs and advise patients properly. The didactic concept of the book has been developed on the author’s own pharmacology courses for which he has received numerous teaching awards. The book takes advantage of the learning spiral, in which material is presented repeatedly from various angles.
Balloon Kyphoplasty
This book focuses on balloon kyphoplasty and alter- tive minimally invasive treatments for stabilization of osteoporotic vertebral fractures. The optimal treatment of a patient with osteoporotic vertebral fractures requires an interdisciplinary - proach, and therefore our book draws on the expertise of orthopedic surgeons, traumatologists and neu- surgeons, and also includes a chapter on medical treatment.
Ballistic Trauma : A Practical Guide
Ballistic Trauma: A Practical Guide provides a concise guide to the clinical and operational issues surrounding the management of the ballistic casualty. The book crystallizes the knowledge and experience accrued by those dealing with ballistic trauma on a regular basis and extends this to those who have to manage these patients on an occasional basis only.
Baculovirus : Methods and protocols
Provides up-to-date guidance on techniques used to work with baculoviruses and insect cells. The book provides basic methods to create recombinant baculoviruses, to improve productivity, to produce a variety of products, to purify products, to quantify baculovirus stocks or to quantify product produced, and it concludes with alternative uses of either baculovirus or insect cells as tools. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Bacteriophage therapy: From lab to clinical practice
Details new and updated experimental approaches for isolating, formulating, and engineering bacteriophage medicinal products. Authored by leading experts and written in the highly successful Methods in Molecular Biology series format, each chapter includes introductions to their respective topics, lists of the necessary materials and reagents, step-by-step reproducible laboratory protocols, and valuable tips for troubleshooting and avoiding known pitfalls.
Bacteriocins : Ecology and Evolution
Microbes produce an extraordinary array of defense systems. These include bacteriocins, a class of antimicrobial molecules with narrow killing spectra, produced by bacteria. The book describes the diversity and ecological role of bacteriocins of Gram-positive and Gram-negative bacteria, presenting a new classification scheme for the former and a state-of-the-art look at the role of bacteriocins in bacterial communication. It discusses the molecular evolution of colicins and colicin-like bacteriocins, and provides a contemporary overview of archaeocins, bacteriocin-like antimicrobials produced by archaebacteria. Furthermore, various modeling (in silico) studies elucidate the role of bacteriocins in microbial community dynamics and fitness, delving into rock-paper-scissors competition and the counter-intuitive survival of the weakest. The book makes compelling reading for a multi-faceted scientific audience, including those working in the fields of biodiversity and biotechnology, notably in the human and animal health domain.
Bacterial virulence factors and Rho GTPases
The authors of this volume present the synthesis on how the various host cellular Rho GTPases activities are manipulated by bacteria to fulfill their virulence.
Bacterial signal transduction : Networks and drug targets
Interactions among different TCSs enable one system to respond to multiple signals, which is important for bacteria to minutely adjust themselves to complex environmental changes. Such interactions are found or predicted in various bacteria in this book. Over the past decade, a vast amount of exciting new information on the signal transduction pathway in bacteria has been brought to light. Reports on these develop› ments have been put together in this book, Bacterial Signal Transduction: Networks andDrug Targets. This book Offers an incentive for graduate students, academic scientists, and researchers in the pharmaceutical industry to further elucidate the TCS networks and apply them in the search for novel drugs.
Bacterial secretion systems : Methods and protocols
Cover techniques used to study secretion systems. Chapters focus on identifying and localizing the different subunits, defining interactions within subunits, monitoring conformational changes, purifying and imaging of large complexes, defining the assembly pathway by fluorescence microscopy and the role of energy during assembly and/or secretion, identifying secreted effectors as well as using reporters to follow effector transport. Written in the highly
Bacterial regulatory RNA : Methods and protocols
Details new and updated methods used for studying prokaryotic non-coding RNAs and their protein accomplices. Chapters detail discovery of ncRNAs, characterization of their structure, functions, and their interactomes. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Bacterial Physiology : A Molecular Approach
The application of new molecular methodologies in the study of bacterial behaviour and cell architecture has enabled new revolutionary insights and discoveries in these areas. While this has also raised a number of scientific mysteries about bacteria, it certainly improved our understanding of these organisms as complex and adaptive entities rather than just simple tiny buckets of enzymes. The value of this recent knowledge in bacterial physiology is not only restricted to fundamental biology, but it also extends to biotechnology and drug-discovery disciplines where understanding cell behaviour and structure is essential for better exploitation of useful bacteria and effective eradication of harmful ones. This makes a new text accommodating recent developments in bacterial physiology highly relevant to a wide range of readership including those interested in basic and applied knowledge.
Bacterial Genomes and Infectious Diseases
This book imparts fundamental knowledge on the structure, organization, and evolution of bacterial genomes. The value and power of comparative genomics and proteomics, bioinformatics, microarrays, and knockout animal models in analyzing genomes, bacteria-host interactions and disease are demonstrated. Also discussed are the genomes of virulent and nonvirulent strains and species, origin and evolution of pathogens, different models of bacteria-host interactions, and diseases mechanisms.
Bacterial Fish Pathogens : Disease of Farmed and Wild Fish
This completely revised and updated edition of Bacterial Fish Pathogens is a comprehensive discussion of the biological aspects of the bacterial taxa which cause disease in fish. Since the 3rd edition was published in 1999, much has changed in the control of disease of farmes and wild fish. New pathogens such as Pasteurella skyensis have been described, and antimicrobial compounds for the control of disease have been replaced by alternative methods, such as probiotics. Consideration is given to all the bacterial taxa which have at some time been reported as fish pathogens, whether they are secondary invaders of already damaged tissues or serious, primary pathogens.
Bacterial chromatin : Methods and protocols
Brings together new and updated methods to explore the structure and function of bacterial chromatin from molecular to the cellular scale. Chapters detail experimental protocols of in vivo and in vitro approaches, approaches to genome structure modeling, and data analysis. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.
Bacterial Biofilms
This volume tends to focus on the biology of biofilms that affect human disease. It opens with chapters that provide the reader with current perspectives on biofilm development, physiology, environmental and regulatory effects, the role of quorum sensing, and resistance/phenotypic persistence to antimicrobial agents during biofilm growth. The next chapters are devoted to common problematic biofilms, those that colonize venous and urinary catheters. The final series of chapters examines biofilm formation by four species that are important pathogens and well studied models, one of which, Yersinia pestis, cleverly adopts a biofilm state of growth within its insect vector to promote disease transmission to mammalian hosts.
Bacterial and Bacteriophage Genetics
Genetic investigations and manipulations of bacteria and bacteriophage have made vital contributions to our basic understanding of living cells and to the development of molecular biology and biotechnology. This volume is a survey of the genetics of bacteria and their viruses, and it provides students with a comprehensive introduction to this rapidly changing subject. The book is written for upper level undergraduates and beginning graduate students, particularly those who have had an introductory genetics course.
