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Bioactive Heterocycles IV
This volume contains nine more contributions from expert researchers of the?eld, providing readers with in depth and current research results regarding therespective topics. In the?rst chapter, Flemming et al. review the chemistry, biosynthesis, metabolism and biological activities of tetrahydrocannabinol and its deri- tives. Hansch and Verma contribute to the quantitative structure-activity re- tionship (QSAR) analysis of heterocyclic topoisomerase I and II inhibitors. These inhibitors, knowntoinhibit either enzyme, actasantitumoragentsand are currently used in chemotherapy and in clinicaltrials. In the third chapter, Khan reviews some aspects of molecular modeling studies on biologically active alkaloids.
Bidding Strategies in Agent-Based Continuous Double Auctions
Presents a new bidding strategy for agents to adopt in CDAs and propose tools to enhance the performance of existing bidding strategies in CDAs. The superior performance of the new bidding strategy as well as the tools presented in this book are illustrated through extensive experiments.
Being apart from reasons : The role of reasons in public and private moral decision-making
The book presents objections to the most common response given by contemporary legal and political theorists to the moral complexity of decision-making in modern societies, namely: the attempt to release public agents from their argumentative burden by insulating a particular set of reasons from the general.
Bargaining Power Effects in Financial Contracting : A Joint Analysis of Contract Type and Placement Mode Choices
The aim of this dissertation is to examine bargaining power effects in financial contracting. In particular power effects on firms' choices of contract type (debt vs. equity) and placement mode (public offering vs. private placement)
Baculovirus : Methods and protocols
Provides up-to-date guidance on techniques used to work with baculoviruses and insect cells. The book provides basic methods to create recombinant baculoviruses, to improve productivity, to produce a variety of products, to purify products, to quantify baculovirus stocks or to quantify product produced, and it concludes with alternative uses of either baculovirus or insect cells as tools. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Bacteriophage therapy: From lab to clinical practice
Details new and updated experimental approaches for isolating, formulating, and engineering bacteriophage medicinal products. Authored by leading experts and written in the highly successful Methods in Molecular Biology series format, each chapter includes introductions to their respective topics, lists of the necessary materials and reagents, step-by-step reproducible laboratory protocols, and valuable tips for troubleshooting and avoiding known pitfalls.
Bacteriophage therapy : a potential solution for antibiotic resistance crisis
For many years, humans have been fighting with bacteria, in a matter of fact, bacteria have been winning for the last decade, becoming resistant to every weapon we have; The antibiotics. In order to win the fight humans had to think of alternative ways, like viruses. There is a special type of viruses that have been in a war with bacteria for millenniums, Bacteriophages. Bacteriophages (or phages), the most abundant viral entity of the planet. On the basis of their unique characteristics and anti-bacterial property, phages are being the freshly evaluated taxonomically. Phages replicate inside the host either by lytic or lysogenic mode after infecting and using the cellular machinery of a bacterium. Phage became an important agent for combating pathogenic bacteria in clinical treatments and its related research gained momentum. However, due to recent rise of bacterial resistance on antibiotics, applications of phage (phage therapy) become an unavoidable option of research. In this dissertation, the advantage and limitations of Bacteriophages for use in humans will be discussed. Furthermore, this dissertation deals with recent development of its application in the areas of biotechnology.
Bacterial regulatory RNA : Methods and protocols
Details new and updated methods used for studying prokaryotic non-coding RNAs and their protein accomplices. Chapters detail discovery of ncRNAs, characterization of their structure, functions, and their interactomes. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Bacterial chromatin : Methods and protocols
Brings together new and updated methods to explore the structure and function of bacterial chromatin from molecular to the cellular scale. Chapters detail experimental protocols of in vivo and in vitro approaches, approaches to genome structure modeling, and data analysis. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.
Bacterial Biofilms
This volume tends to focus on the biology of biofilms that affect human disease. It opens with chapters that provide the reader with current perspectives on biofilm development, physiology, environmental and regulatory effects, the role of quorum sensing, and resistance/phenotypic persistence to antimicrobial agents during biofilm growth. The next chapters are devoted to common problematic biofilms, those that colonize venous and urinary catheters. The final series of chapters examines biofilm formation by four species that are important pathogens and well studied models, one of which, Yersinia pestis, cleverly adopts a biofilm state of growth within its insect vector to promote disease transmission to mammalian hosts.
Autonomous Robots and Agents
This book deals with the theoretical and methodological aspects of incorporating intelligence in Autonomous Robots and Agents. Challenges faced in the real world to accomplish complex tasks, which require collaborative efforts, and methods to overcome them, are detailed. Several informative articles deal with navigation, localization and mapping of mobile robots, a problem that engineers and researchers are grappling with all the time.This edited volume is targeted to present the latest state-of-the-art methodologies in Robotics. It is a compilation of the extended versions of the very best papers selected from the many that were presented at the 3rd International Conference on Autonomous Robots and Agents (ICARA 2006) which was held at Palmerston North, New Zealand from 11-14 December, 2006. Scientists and engineers who work with mobile robots will find this book very useful and stimulating.
Autonomous intelligent systems : Multi-agents and data mining ; 2nd International workshop, AIS-ADM 2007, St. Petersburg, Russia, June 3-5, 2007, Proceedings
MAS offiers powerful metaphors for information system conceptualization, a range of new techniques, and technologies specifically focused on the design and implementation of lar- scale open distributed intelligent systems. KDD also provides intelligent inf- mation technology with powerful ideas, algorithms, and software means to help cope with the main problem of artificial intelligence, formulated in the we- known question “Where does the knowledge come from?”, thus actually making modern applications intelligent and adaptive. The evident recent trend in both science and industry is to integrate and take advantage of both technologies. The existing experience with combined application of multi-agent technology to design architectures of distributed (- erarchical and peer-to-peer) data mining and KDD systems, as well as the u- lization of data mining and KDD achievements to provide enhanced intelligence of MAS, confirms the fact that both technologies are capable of mutual enri- ment and their integrateduse may result in intelligent information systems with new emergent properties.
Autonomous intelligent systems : Agents and data mining ; International workshop, AIS-ADM 2005
This book constitutes the refereed proceedings of the International Workshop on Autonomous Intelligent Systems: Agents and Data Mining, AIS-ADM 2005, held in St. Petersburg, Russia in June 2005. The 17 revised full papers presented together with 5 invited papers and the abstract of an invited talk were carefully reviewed and selected from 29 submissions. The papers are organized in topical sections on agent-based data mining issues, ontologies and Web mining, and applications and case studies.
Autonomes fahren : Technische, rechtliche und gesellschaftliche aspekte = Autonomous driving : Technical, legal and social aspects
This book provides answers to a wide range of these and other questions. Experts from Germany and the USA describe central topics related to the automation of vehicles on public roads from an engineering and social science perspective. They show which "decisions" are required of an autonomous vehicle or which "ethics" must be programmed. The authors discuss expectations and concerns that characterize the individual and societal acceptance of autonomous driving. An increased safety potential through autonomous vehicles is compared to the challenges and solution approaches that play a role in securing the safety concept. In addition, they explain what possibilities for change and opportunities arise for our mobility and the reorganization of traffic, not least for freight traffic. The book thus offers an up-to-date, comprehensive and scientifically sound examination of the topic of "autonomous driving".
Automated reasoning with analytic tableaux and related methods ; International Conference, TABLEAUX 2005, Koblenz, Germany, September 14-17, 2005, Proceedings
This volume contains the research papers presented at the International C- ference on Automated Reasoning with Analytic Tableaux and Related Methods (TABLEAUX2005)heldSeptember 2005inKoblenz,Germany. which included conferences covering a broad spectrum of topics and intere- ing ?elds of application for tableau-based methods: arti?cial intelligence (KI), multi-agent systems (MATES), automated reasoning and knowledge represen- tion (FTP), and software engineering and formal methods (SEFM).
Autoimmunity : Methods and protocols
Brings together a comprehensive and up-to-date collection of protocols that reflect the diverse experimental strategies. Chapters detail T-cell, macrophage characterization, neutrophil functional assays, organoid culture methods, spatial transcriptomics, RNA FISH, microRNA profiling, and ribosome profiling. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.
Augmented Humanity : Being and Remaining Agentic in a Digitalized World
This book will examine the implications of digitalization for the understanding of humanity, conceived as a community of intelligent agency. It addresses important topics across a range of social and behavioral theories and identifies a range of novel mechanisms and their social behavioral effects. Across the book, the author highlights the expansion of intelligent processing capability brought about by digitalization and the challenges this exposes for integrating artificial and human capabilities
Attention in Cognitive Systems : Theories and Systems from an Interdisciplinary Viewpoint ; 4th International Workshop on Attention in Cognitive Systems, WAPCV 2007 Hyderabad, India, January 8, 2007 Revised Selected Papers
The embodied nature of sensory-motor intelligence requires a continuous and focused interplay between the control of motor activities and the interpretation of feedback from perceptual modalities. Decision making about the selection of information from the incoming sensory stream – in tune with contextual processing on a current task and an agent’s global objectives – becomes a further challenging issue in attentional control. Attention must operate at interfaces between bottom-up driven world int- pretation and top-down driven information selection, thus acting at the core of arti?cial cognitive systems. These insights have already induced changes in AI-related disciplines, such as the design of behavior-based robot control and the computational modeling of animats. Today, the development of enabling technologiessuch as autonomous robotic systems,miniaturizedmobile–evenwearable–sensors,andambientintelligence systems involves the real-time analysis of enormous quantities of data. These data have to be processed in an intelligent way to provide “on time delivery” of the required relevant information. Knowledge has to be applied about what needs to be attended to, and when, and what to do in a meaningful sequence, in correspondence with visual feedback.
Assessment of the fate and effects of toxic agents on water resources
Like all limited and vulnerable resources, water has become one of the potential targets of terrorists. Coastal lagoons are especially vulnerable as they are densely populated centers of commerce and/or tourism. This volume addresses the basic scientific concepts that must be integrated by decisionmakers to minimize damages and optimize recovery operations in the aftermath of such an attack. Scientists from many disciplines including water resource management, hydrodynamics, aquatic ecology and social science combine their expertise in an effort to assess and model emergency scenarios for coastal lagoon systems. This case study uses existing numerical models such as-EFCD, WASP and AQUATOX are used to demonstrate how to optimize rapid response and decision-making
Aspirin tablet film coated with famotidine
Focuses on enhancing the gastrointestinal tolerance of aspirin tablets by coating them with famotidine, a histamine-2 receptor antagonist known for its ability to reduce stomach acid production. The project aims to investigate the potential of famotidine coating in mitigating the gastric side effects commonly associated with aspirin usage, such as gastric irritation and ulcers. Through a series of in vitro studies, the project will evaluate the effectiveness of famotidine-coated aspirin tablets in reducing gastric mucosal damage and improving overall gastrointestinal safety.
