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Cancer in the Arab World

Over the past few decades, the Arab world has witnessed a swift evolution in healthcare provision. Nonetheless, Arab countries have considerable variability in economic capabilities, resource allocation, and intellectual talent that inevitably reflect on access to modern cancer care and prevention. This book is authored by experts from the Arab world who provide vital information on cancer statistics and risk factors, available clinical care pathways and infrastructure, and prevention programs in their individual countries. The chapters also address specific challenges in each country and insights into future directions to achieve optimal care with conventional and novel diagnostics and therapies to keep up with the era of precision medicine.

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Cancer and War

Armed conflict, especially the most intense types, indirectly impacts civilian mortality. The estimates suggest that almost 30 million civilian deaths were indirectly attributable to armed conflict globally between 1990 and 2017, two thirds of which were due to communicable, maternal, neonatal, and nutritional diseases. Broader and more robust measures of civilian impacts at subnational and national levels are needed to inform policy and advocacy to prevent war and protect civilians. This could include greater use of linkage studies that incorporate data from routine health and demographic sources, exposure to conflict-specific environmental risks, and quantitative epidemiological methods such as national and subnational victimisation surveys.

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Calcium Signalling and Disease : Molecular Pathology of Calcium

This topic is a new entry in the area of cellular calcium signaling: yet, it now spans the entire area, with discoveries that cover both genetic and acquired pathologies, even offering glimpses in the direction of therapy.Cellular calcium homeostasis, and thus calcium signalling, is mainly regulated by membrane intrinsic proteins and calcium sensor proteins. Both classes may be involved in pathological processes that affect both human and animals, ranging from common and important diseases (e.g. migraine, diabetes, epilepsia, manic depression, infertility, various types of cancer, Alzheimer’s disease, muscular dystrophy) to rare genetic conditions (e.g., a number of genetic heart conditions, autoimmune retinopathies, night blindness, hereditary amyloid polyneuropathy, malignant hyperthermia, cerebellar ataxia, atherothrombotic disease).

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Business and Professional Ethics

Learn why ethical behavior is so important and how to recognize potential pitfalls that involve much more than memorizing rules. You master the skills to develop a corporate culture of integrity that maintains stakeholder support and enables directors and auditors to complete their jobs. You also learn how to use ethical strategies to make decisions, as this edition examines the latest information on governance scandals, legal liability and professional accounting and auditing issues.

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Bulk Fill Resin Composites in Dentistry : A Clinical Guide

Dedicated to all relevant aspects of bulk fill materials and their uses in clinical practice. Today, we count over 30 different bulk fill materials, which can be used in the dental clinic. The composition of bulk fill materials and their different modes of application for moderate to large direct resin restorations placement are explained in this book. It is written by a group of international specialists and allows the reader to evaluate available materials, learn predictable techniques and evaluate long term survival as well as future developments. The book covers all fields related to the history of bulk fill composites, their composition and physical properties, and a step by step guide to their successful clinical applications.

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Building systems in interior design

Takes an entirely new approach to teaching this essential topic for Architects, Designers and Building Engineers. Written to prepare students for the real world and packed with practical examples, the book will foster an understanding of specific issues that are critical to those features of technical systems that most directly affect design. The book stresses the ever-present nature of these systems: they are everywhere, all the time. Taking a design oriented view, it outlines what can and cannot be done, and provides the student with the know-how and confidence to defend and promote their design intent when working with other industry professionals.

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Building information modeling : BIM in current and future practice

"Thought leaders from universities and professional practice composed essays exploring BIM's potential to improve the products and processes of architectural design including the structure and content of the tools themselves. These authors provide insights for assessing the current practice and research directions of BIM and speculate about its future. Design Thinking and BIM / BIM Analytics / Comprehensive BIM / Reasoning with BIM / Professional BIM / BIM Speculations"

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Broadband in Europe: How Brussels Can Wire the Information Society

Broadband is a key enabler of the information society, increasing productivity and competitiveness across all sectors of the economy. Unlike traditional n- rowband connections, broadband provides high speed, always-on connections to the Internet and supports innovative content and services. Direct consumer welfare gains from mass-market adoption of broadband across the EU could easily reach 50 billion euros or more per annum. This is quite apart from the more profound societal shifts that ubiquitous broadband could bring. It may allow the individual to distribute content and ideas independent of traditional media and bring together communities of interest without regard to borders. Public policy for broadband will have a big impact on whether and how quickly these benefits are realised. Getting policy right could bring large benefits for consumers.

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Bringing the sun down to earth : Designing inexpensive instruments for monitoring the atmosphere

The book describes in detail how to design, build, calibrate, and use inexpensive instruments for measuring solar radiation, ranging from total radiation from the entire sky to narrow spectral bands of radiation travelling along a path directly from the sun. Students and their teachers will learn a great deal about weather, the seasons, and the atmosphere, and they will develop a much better understanding of how to measure the physical world around them.

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Breast cancer chemosensitivity

In Breast Cancer Chemosensitivity, a group of world leading experts review critical aspects of resistance to systemic therapy in breast cancer patients. Beginning with a clinical overview of the problem Breast Cancer Chemosensitivity moves on to focus on the latest findings of molecular mechanisms of drug resistance. These include in-depth discussions on multidrug resistance by P-glycoprotein and the multidrug resistance protein family, resistance to therapeutic agent-induced apoptosis, cell cycle deregulation, deregulation of DNA repair, loss of tumor suppressor genes, integrin-mediated adhesion, insulin-like growth factors, epidermal growth factor, and ErbB2 in modulating breast cancer response to systemic therapy, especially, certain chemotherapeutic agents. Breast Cancer Chemosensitivity provides an example of using novel approaches for chemosensitization of breast cancer cells that gives readers an idea about the future direction in breast cancer treatment.

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Brain thoughts recognition

Humans controlling machines with their minds may sound like something from a scifi movie, but it’s becoming a reality through brain-computer interfaces BCI. Where BCI technology allows a human brain and an external device to talk to each other—to exchange signals. It gives humans the ability to directly control machines, without the physical constraints of the body. There are two ways to implement the BCI: Noninvasive tools often use sensors applied on or near the head to track and record brain activity, or Invasive BCI would require surgery. Electronic devices would need to be implanted beneath the skull, directly into the brain, to target specific sets of neurons. In order to implement a non-invasive BCI in a mobile phone, this study developed a mobile application to help paralyzed people who do not have the ability to use their phones to spend their basic daily needs, such as using the keyboard and interacting with PDF, etc.

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Boundary Element Analysis : Mathematical Aspects and Applications

This volume contains eleven state of the art contributions on boundary integral equation and boundary element methods. Beside some historical and more analytical aspects in the formulation and analysis of boundary integral equations also modern fast boundary element methods are described and analyzed from a mathematical point of view. In addition, engineering and industrial applications of those methods are presented showing the ability of state of the art boundary element methods to solve challenging problems from different fields of applications. This book is addressed to researchers, graduate students and practitioners working on and using boundary element methods. All contributions also show the great achievements of interdisciplinary research between mathematicians and engineers, with direct applications in industry.

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Borrelia burgdorferi : Methods and protocols

Covers the latest advancements and techniques used to understand the fastidious bacterium, Borrelia burgdorferi, and its significance in infectious disorders by combining both conventional and cutting-edge approaches. This book covers diverse topics, including direct detection, diagnostic methods, immune response analysis, alternative model systems, advanced proteomics, social media analysis, and clinical research. It also discusses unconventional wet lab research such as content analysis, the use of ChatGPT, clinical algorithms for chronic Lyme, establishment of a pregnancy Lyme disease biobank, and investigates Lyme in pregnant women. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

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Bond Portfolio Optimization

1 The tools of modern portfolio theory are in general use in the equity markets, either in the form of portfolio optimization software or as an accepted frame- 2 work in which the asset managers think about stock selection. In the ?xed income market on the other hand, these tools seem irrelevant or inapplicable. Bond portfolios are nowadays mainly managed by a comparison of portfolio 3 4 risk measures vis ¶a vis a benchmark. The portfolio manager’s views about the future evolution of the term structure of interest rates translate th- selves directly into a positioning relative to his benchmark, taking the risks of these deviations from the benchmark into account only in a very crude 5 fashion, i.e. without really quantifying them probabilistically. This is quite surprising since sophisticated models for the evolution of interest rates are commonly used for interest rate derivatives pricing and the derivation of ?xed 6 income risk measures.

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Biotechnologies for plant mutation breeding : Protocols

This book offers 19 detailed protocols on the use of induced mutations in crop breeding and functional genomics studies, which cover topics including chemical and physical mutagenesis, phenotypic screening methods, traditional TILLING and TILLING by sequencing, doubled haploidy, targeted genome editing, and low-cost methods for the molecular characterization of mutant plants that are suitable for laboratories in developing countries. The collection of protocols equips users with the techniques they need in order to start a program on mutation breeding or functional genomics using both forward and reverse-genetic approaches. Methods are provided for seed and vegetatively propagated crops (e.g. banana, barley, cassava, jatropha, rice) and can be adapted for use in other species.

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Biosolids engineering and management

Biosolids Engineering and Management, is a collection of methods of practical design, calculation and numerical examples that illustrate how organized, analytical reasoning can lead to the discovery of clear, direct solutions, especially in the areas of biosolids management, treatment, disposal and beneficial use. The book’s including sludge and biosolids transport, pumping and storage, sludge conversion to biosolids, chlorination, stabilization, regulatory requirements, costs, agricultural land application, landfill, ocean disposal, combustion, incineration and sludge treatment process selection.

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Biomimetics for architecture & design : Nature - analogies - technology

Provides the readers with a timely guide to the application of biomimetic principles in architecture and engineering design. As a result of a combined effort by two internationally recognized authorities, the biologist Werner Nachtigall and the architect Göran Pohl, the book describes the principles which can be used to compare nature and technology, and at the same time it presents detailed explanations and examples showing how biology can be used as a source of inspiration and “translated” in building and architectural solutions (biomimicry). Even though nature cannot be directly copied, the living world can provide architects and engineers with a wealth of analogues and inspirations for their own creative designs. But how can analysis of natural entities give rise to advanced and sustainable design? By reporting on the latest bionic design methods and using extensive artwork, the book guides readers through the field of nature-inspired architecture, offering an extraordinary resource for professional architects, engineers, designers and urban planners, as well as for university teachers, researchers and students.

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Biomedical Informatics : Computer Applications in Health Care and Biomedicine

This series is directed to healthcare professionals who are leading the transformation of health care by using information and knowledge. Launched in 1988 as Computers in Health Care, the series offers a broad range of titles: some addressed to specific prof- sions such as nursing, medicine, and health administration; others to special areas of practice such as trauma and radiology.

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Biomarkers in periodontal health and disease : Rationale, benefits, and Future directions

This book examines all aspects of the progress being made towards the development of highly specific and sensitive biomarkers that will overcome the shortcomings of clinical assessments in periodontics. Readers will find the book to be an ideal summary of the state of the art in the field as biomarkers emerge that promise to facilitate periodontal diagnostics and permit timely, personally tailored interventions.

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Bioethics across the globe : Rebirthing bioethics

This book addresses a variety of issues relating to bioethics, in order to initiate cross-cultural dialogue. Beginning with the history, it introduces various views on bioethics, based on specific experiences from Japan. It describes how Japan has been confronted with Western bioethics and the ethical issues new to this modern age, and how it has found its foothold as it decides where it stands on these issues. In the last chapter, the author proposes discarding the overarching term ‘Global Bioethics’ in favor of the new term, ‘Bioethics Across the Globe (BAG)’, which carries a more universal connotation.

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