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Genome editing in neurosciences
Innovations in molecular biology are allowing neuroscientists to study the brain with unprecedented resolution, from the level of single molecules to integrated gene circuits. Chief among these innovations is the CRISPR-Cas genome editing technology, which has the precision and scalability to tackle the complexity of the brain. This Colloque Médecine et Recherche has brought together experts from around the world that are applying genome editing to address important challenges in neuroscience, including basic biology in model organisms that has the power to reveal systems-level insight into how the nervous system develops and functions as well as research focused on understanding and treating human neurological disorders.
Genome editing in drug discovery
In Genome Editing in Drug Discovery, a team of distinguished biologists delivers a comprehensive exploration of genome editing in the drug discovery process, with coverage of the technology’s history, current issues and techniques, and future perspectives and research directions. The book discusses techniques for disease modeling, target identification with CRISPR, safety studies, therapeutic editing, and intellectual property issues.
Genome Editing : Gene Therapy or Gene Optimization?
Genome editing technology is considered one of the most revolutionary techniques lately. The ability of modifying the human genome has been one of the biggest dreams for therapist for the reason that the genetic modification with exogenous DNA can be considered a problem solver for many diseases and disorders (genetic disorders), especially those with high risks and low survival rates, on this case, gene therapy appears as the tool to be used, with its many protocols and approaches. Gene therapy is based on delivering a therapeutic gene throw suitable vectors, which is most of the time-modified viruses to carry the therapeutic genes to the target cells and so on providing the functional copy of the defective gene.
Genitourinary Pain and Inflamation : Diagnosis And Management
Genitourinary Pain and Inflammation: Diagnosis and Management of GU-ITIS is a compilation of skilled creativity based upon critical review of the literature, consensus reports, and professional experiences. It includes detailed chapters that address iatrogenic causes of GU inflammation, caused by catheters, prosthetics, radiation, or chemotherapy.
Génetique statistique = Statistical genetics
Presents the main statistical tools useful in genetics: significance tests, analysis methods based on the likelihood function, EM algorithm, modeling, analysis of variance, hierarchical classifications, multiple comparisons, etc. All of them shed light on a number of biological phenomena such as carcinogenesis, population genetics, Hardy-Weinberg equilibrium, natural selection, mutations, heredity, coalescence processes, and even evolution. This book is intended for mathematicians and biologists alike. Written with a great concern for clarity, it is also accessible to non-specialists who will be able, thanks to it, to strengthen their theoretical base and above all to develop their know-how through very concrete applications.
Genetics of Adaptation
What is the genetic basis of adaptive evolution? In this volume, a new generation of biologists have taken up this challenge. Using advances in both molecular genetic and statistical techniques, evolutionary geneticists have made considerable progress in this emerging field. In this volume, a diversity of examples from plant and animal studies provides valuable information for those interested in the genetics and evolution of complex traits.
Genetics and regulation of nitrogen fixation in free-Living bacteria
This book is the second volume of a seven-volume series, which covers all fields of research related to nitrogen fixation - from basic studies through applied aspects to environmental impacts. Volume II provides a comprehensive and detailed source of information concerning the genetics and regulation of biological nitrogen fixation in free-living prokaryotes.
Genetics and Genomics of Soybean
The book covers recent progress on genome research in soybeans, including the genetic map with classical, RFLP, SSR and SNP markers; genomic and cDNA libraries, functional genomics platforms (e.g., cDNA, Affymetrix and oligonucleotide based DNA microarrays); physical maps, and the efforts to fully sequence the genome. Given the pending release of the soybean genome sequence, through the efforts of the Department of Energy’s Joint Genome Institute, this book will stand as a critical source of information on soybean.
Genetic testing in reproductive medicine
Illustrates the importance and significance of molecular genetic testing in reproductive disorders. The present book covers the genetic testing in various reproductive system anomalies, including disorders of sexual development, male infertility (Y deletions, autosomal mutations, sperm DNA fragmentation), female infertility (PCOS and POF), mitochondrial DNA testing for oocyte quality, recurrent pregnancy loss, pre-term birth, endometrial receptivity, prenatal genetic screening, reproductive carrier screening, preimplantation genetic screening, endometrial cancer, cervical cancer and other related reproductive health disorders. Microbiome testing and its contribution to genetic testing in reproductive medicine are also discussed. Covers ethical, moral and technical challenges in genetic testing in reproductive medicine. The book aims to set up a standard with regard to genetic testing in the reproductive medicine field, encourage further data generation, and provide food for thought in the areas of lacunae.
Genetic Systems Programming : Theory and Experiences
This book is devoted to reporting innovative and significant progress about the contribution of genetic programming in systems programming. The contributions of this book clearly demonstrate that genetic programming is very effective in solving hard and yet-open problems in systems programming. Followed by an introductory chapter, in the remaining contributed chapters, the reader can easily learn about systems where genetic programming can be applied successfully. These include but are not limited to, information security systems, compilers, data mining systems, stock market prediction systems, robots and automatic programming.
Genetic surgery : from genes to solutions
As a tool for modifying the genome, gene editing technologies has developed rapidly in recent years, the application of these technologies in basic biomedical research has yielded significant advances in identifying and studying key molecular targets relevant to human diseases and their treatment. The clinical translation of genome editing techniques offers unprecedented biomedical engineering capabilities in the diagnosis, prevention, and treatment of disease or disability...
Genetic rogramming ; Vol. 3447 : 8th European conference, EuroGP 2005, Lausanne, Switzerland, March 30-April 1, 2005, Proceedings
In this volume we present the contributions for the 18th European Conference on Genetic Programming (EuroGP 2005). The conference took place from 30 March to 1 April in Lausanne, Switzerland. EuroGP is a well-established conf- ence and the only one exclusively devoted to genetic programming. All previous proceedings were published by Springer in the LNCS series. From the outset, EuroGP has been co-located with the EvoWorkshops focusing on applications of evolutionary computation. Since 2004, EvoCOP, the conference on evolutionary combinatorial optimization, has also been co-located with EuroGP, making this year’s combined events one of the largest dedicated to evolutionary computation in Europe. Genetic programming (GP) is evolutionary computation that solves complex problems or tasks by evolving and adapting a population of computer programs, using Darwinian evolution and Mendelian genetics as its sources of inspiration. Some of the 34 papers included in these proceedings address foundational and theoretical issues and there is also a wide variety of papers dealing with di?erent application areas, such as computer science, engineering, language processing, biology and computational design, demonstrating that GP is a powerful and practical problem-solving paradigm.
Genetic Programming Theory and Practice V
Genetic Programming Theory and Practice V was developed from the fifth workshop at the University of Michigan’s Center for the Study of Complex Systems to facilitate the exchange of ideas and information related to the rapidly advancing field of Genetic Programming (GP). Contributions from the foremost international researchers and practitioners in the GP arena examine the similarities and differences between theoretical and empirical results on real-world problems. The text explores the synergy between theory and practice, producing a comprehensive view of the state of the art in GP application.
Genetic Programming Theory and Practice IV
Genetic Programming Theory and Practice IV was developed from the fourth workshop at the University of Michigan’s Center for the Study of Complex Systems to facilitate the exchange of ideas and information related to the rapidly advancing field of Genetic Programming (GP). Contributions from the foremost international researchers and practitioners in the GP arena examine the similarities and differences between theoretical and empirical results on real-world problems.
Genetic Programming Theory and Practice III
Genetic Programming Theory and Practice III explores the emerging interaction between theory and practice in the cutting-edge, machine learning method of Genetic Programming (GP). This contributed volume was developed from the third workshop at the University of Michigan’s Center for the Study of Complex Systems to facilitate the exchange of ideas and information related to this rapidly advancing field. The text provides a cohesive view of the issues facing both practitioners and theoreticians and examines the synergy between GP theory and application.
Genetic programming IV : Routine human-competitive machine intelligence
Genetic Programming IV: Routine Human-Competitive Machine Intelligence presents the application of GP to a wide variety of problems involving automated synthesis of controllers, circuits, antennas, genetic networks, and metabolic pathways. The book describes fifteen instances where GP has created an entity that either infringes or duplicates the functionality of a previously patented 20th-century invention, six instances where it has done the same with respect to post-2000 patented inventions, two instances where GP has created a patentable new invention, and thirteen other human-competitive results. The book additionally establishes: GP now delivers routine human-competitive machine intelligence GP is an automated invention machine GP can create general solutions to problems in the form of parameterized topologies GP has delivered qualitatively more substantial results in synchrony with the relentless iteration of Moore's Law
Genetic Programming ; Vol. 3905 ; 9th European Conference, EuroGP 2006, Budapest, Hungary, April 10-12, 2006. Proceedings
This book constitutes the refereed proceedings of the 9th European Conference on Genetic Programming, EuroGP 2006, held in Budapest, Hungary, in April 2006, colocated with EvoCOP 2006. The 21 revised plenary papers and 11 revised poster papers were carefully reviewed and selected from 59 submissions. The papers address fundamental and theoretical issues, along with a wide variety of papers dealing with different application areas, such as computer science, engineering, machine learning, Kolmogorov complexity, biology and computational design.
Genetic Programming ; 11th European Conference, EuroGP 2008, Naples, Italy, March 26-28, 2008. Proceedings
The 11th European Conference on Genetic Programming, EuroGP 2008, took place in Naples, Italy from 26 to 28 March in the University of Naples Congress Centre with spectacular views over the Gulf of Naples. This volume contains the papers for the 21 oral presentations and 10 posters that were presented during this time. A diverse array of topics were covered refecting the current state of research in the ?eld of Genetic Programming, including the latest work on representations, theory, operators and analysis, evolvable hardware, agents and numerous applications. A rigorous, double-blind peer review process was employed, with each s- mission reviewed by at least three members of the international Program C- mittee.
Genetic Programming ; 10th European Conference, EuroGP 2007, Valencia, Spain, April 11-13, 2007, Proceedings
This book constitutes the refereed proceedings of the 10th European Conference on Genetic Programming, EuroGP 2007, held in Valencia, Spain in April 2007 colocated with EvoCOP 2007.
Genetic programming : Theory and practice II
This volume explores the emerging interaction between theory and practice in the cutting-edge, machine learning method of Genetic Programming (GP). The contributions developed from a second workshop at the University of Michigan's Center for the Study of Complex Systems where leading international genetic programming theorists from major universities and active practitioners from leading industries and businesses met to examine how GP theory informs practice and how GP practice impacts GP theory. Chapters include such topics as financial trading rules, industrial statistical model building, population sizing, the roles of structure in problem solving by computer, stock picking, automated design of industrial-strength analog circuits, topological synthesis of robust systems, algorithmic chemistry, supply chain reordering policies, post docking filtering, an evolved antenna for a NASA mission and incident detection on highways.
