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Heterogeneity in statistical genetics : How to assess, address, and account for mixtures in association studies
Heterogeneity, or mixtures, are ubiquitous in genetics. Even for data as simple as mono-genic diseases, populations are a mixture of affected and unaffected individuals. Still, most statistical genetic association analyses, designed to map genes for diseases and other genetic traits, ignore this phenomenon.In this book, we document methods that incorporate heterogeneity into the design and analysis of genetic and genomic association data. Among the key qualities of our developed statistics is that they include mixture parameters as part of the statistic, a unique component for tests of association. A critical feature of this work is the inclusion of at least one heterogeneity parameter when performing statistical power and sample size calculations for tests of genetic association.
Heterocyclic Supramolecules I
Contributing to this book of six chapters were 14 scientists working in the field of supramolecular chemistry, with a special focus on molecular recognition, functional materials, and nanocarbon science. … Overall, this book is an informative summary on the progress that researchers have made over the past decade toward generating useful functional materials from heterocyclic supramolecules. This is an advanced text that should be most useful to those with an established background in supramolecular sciences and engineering.
Heterocyclic Polymethine Dyes : Synthesis, Properties and Applications
Heterocyclic chemistry is the biggest branch of chemistry covering two-thirds of the chemical literature and this book covers the hot topics of frontier research summarized by reputed scientists in the field.
Heterocyclic Antitumor Antibiotics
Heterocyclic Compounds Includes aspects such as synthesis, reaction mechanisms, structure complexity, properties, reactivity, stability, fundamental and theoretical studies, biology, biomedical studies, pharmacological aspects, applications in material sciences etc. Metabolism will be also included which will provide information useful in designing pharmacologically active agents. Pathways involving destruction of heterocyclic ring will also be dealt with so that synthesis of specifically functionalized non-heterocyclic molecules can be designed. Overall scope is to cover topics dealing with most of the areas of current trends in heterocyclic chemistry which will suit to a larger heterocyclic community.
Heterocycles from Transition Metal Catalysis : Formation and Functionalization
The book provides a representative selection of transition metal catalysed reactions, transformations that are relevant in heterocyclic chemistry. In this way, the authors provide a useful resource for members of the academic community looking for a textbook as well as industrial chemists in search of a reference book. This book is an invaluable resource for synthetic chemists, medicinal chemists, and those more generally interested in applied catalysis.
Heterocycles from Carbohydrate Precursors
This book is a volume in the series Topics in Heterocyclic Chemistry.Itc- ers the key methods used for designing synthetic approaches to heterocycles from carbohydrates and the value and scope of these methods. Carbohydrates are widely distributed in nature and constitute the largest part of renewable biomasses. Moreover, many carbohydrates and their derivatives are comm- cially available at relatively cheap prices. Consequently their utilization is highly encouraged and economically they are of great signifcance. Moreover, carbohydrates are highly functionalized compounds that can be readily deritized and/or cyclized to provide heterocyclic compounds. This book provides a modern account and an up-to-date description of the advancement in the synthesis of diverse heterocycles from carbohydrates. Carbohydrates can be considered as a source of chiral centers in addition to the variable modifcation thereof.
Hermeneutics and Hindu Thought : Toward a Fusion of Horizons
The emergence of Hinduism as a field of study in the Western academia coincides with the development of modern hermeneutics. Despite this coemergence, and the rich possibilities inherent in a dialectical encounter between the theories of modern and pre-modern hermeneutics and those of Hindu hermeneutical traditions, this potential has not been tapped within the boundaries of religious studies. This volume sets out to initiate such an interface.Some essays in this volume, such as those by Shrinivas Tilak, Sharada Sugirtharajah, and Purushottama Bilimoria examine the impact of Western hermeneutics on the Indian religious landscape.
Hermann Cohens Critical Idealism
Publications on Cohen in the English language are small in number and this volume aims to fill the gap. It offers an analysis of Cohen’s System of Philosophy - the three-volume classic on logic, ethics, and aesthetics - and his writings on Judaism and religion. The book highlights Cohen’s contributions in these fields, including his discussions with Maimonides, Leibniz, Kant, and Hegel. It demonstrates the congeniality of Cohen’s critical idealism as expounded in the System and his writings on Judaism, and offers an overview of contemporary Cohen research.
Heritage building conservation : Sustainable and digital modelling
Covers: The technology used to digitally document heritage buildings, including LIDAR, photogrammetry, Heritage Building Information Modelling (HBIM), and Virtual Reality (VR) technologies Introducing a Maintainability Index of Heritage Buildings (MIHB) to support the decision-making and prioritization process for the maintenance of heritage buildings The adaptive reuse of heritage buildings Modelling embodied and operational energy performance Using Chatbot and Blockchain technology to support the management and preservation of heritage buildings Ultimately, this book presents a useful tool for use in heritage management and highlights how the reusability of heritage buildings is critical to the creation and survival of sustainable communities.
Hereditary Peripheral Neuropathies
"Hereditary Peripheral Neuropathies" deals with the Charcot-Marie-Tooth group of neuropathies and related primary hereditary neuropathies. The knowledge in this field has grown exponentially during the last ten years. The book is divided into two sections. The first section deals with the clinical presentation, electrophysiological features and differential diagnosis of these disorders as well as with the general biology of the peripheral nerve. The second section gives a detailed account of the known disease entities. The book will be interesting for both the clinician with a special interest in PNS diseases as well as for the researcher.
Herbs for stress & anxiety : How to make and use herbal remedies to strengthen the nervous system
Treat stress, anxiety, depression, and more with simple herbal remedies that calm your mind, build a healthy nervous system, and promote lasting peace. In this informative guide, renowned herbalist Rosemary Gladstar profiles 21 herbs proven to be effective at soothing common ailments like insomnia, panic attacks, skin conditions, and migraines. With simple directions for making herbal mixtures that can be used in delicious teas, tinctures, and capsules, Gladstar shows you how to harness the power of nature to achieve a more relaxed and fulfilling life.
Herbs for common ailments : How to make and use herbal remedies for home health care
Shows you how to use 56 common herbs to address a wide range of everyday ailments, from burns, wounds, and itchy skin to headaches, congestion, indigestion, strains, bruises, sore throats, coughs, fevers, colic, cramps, and insomnia. She also shows you how to stock a simple first-aid kit with safe, effective herbal remedies.
Herbals of Asia : Prevalent diseases and their treatments
Excellent source of information by identifying hundreds of medicinal herbs and unfolding their medicinal uses for treatment of prevalent diseases Presents recent developments in research on medicinal plants for different diseases, formulation of products, and market strategy Research scholars in relevant field, health practitioners, herbalists and pharmaceutical industries will benefit from the text’s rich list of references as well as plant field photographs Demonstrates the global relevance of sharing local knowledge, and highlights the need to make information on plants available on a worldwide basis
Herbals as nutraceuticals : Their role in healthcare
Herbal nutraceuticals demonstrate a variety of therapeutic benefits and have been found to prevent, treat, and even cure a range of diseases. This new book provides insight into nutraceuticals and their function in human health, highlighting their antimicrobial and immune-inflammatory properties. It describes the nutraceutical properties of various medicinal herbs and details the role of nutraceuticals in treating diseases such as Alzheimer's, Parkinson's, obesity, diabetes, cancer, cardiovascular diseases, skincare issues, and more.
Herbal Products : Toxicology and Clinical Pharmacology
Herbal Products: Toxicology and Clinical Pharmacology, Second Edition builds upon the informative foundation laid by its predecessor. This fully revised and expanded second edition boasts over 200 new references that document efficacy studies and adverse effects and four new chapters devoted to dietary products.
Herbal pharmacopeia : Nanotechnology and advancing drug
Explores the intersection between traditional herbal medicine and cutting-edge nanotechnology. The chapters introduce modern techniques used in herbal extraction and analysis. The principles of drug discovery from plants are discussed, with a focus on the identification and development of bioactive compounds that have therapeutic potential. It discusses the pharmacological properties, biotechnological approaches in drug development, and challenges in the formulation and standardization of herbal medicines. Emerging trends and applications of nanotechnology in herbal pharmacotherapy, such as nanoparticle synthesis, enhanced bioavailability using nanocarriers, safety assessments, novel and targeted delivery systems, and regulatory considerations, are thoroughly discussed. Additionally, it includes a comparative analysis of traditional and nano-formulated approaches and their implementation in clinical settings. Towards the end, the book reviews the regulatory considerations for herbal products and future perspectives in herbal pharmacopeia. This book is intended for researchers, clinicians, and professionals in herbal medicine, pharmacology, and nanotechnology.
Herbal medicine in India : Indigenous knowledge, practice, innovation and its value
Covers Indian herbal medicines, health products, pharmaceuticals, nutraceuticals, and cosmetics. Highlights the status quo and future prospects of traditional medicine in India / Provides information on drug discovery, ethnobotany, isolation of phytochemicals, importance of herbal nutraceuticals, etc. / Covers innovation, validation and IPR issues related to Indian traditional medicine
Herbal immunity boosters against COVID-19
Provides an introduction to COVID-19 and herbal medications that boost the human immune system against SARS-CoV-2. The topics are covered in 7 chapters starting with an introduction to the disease, followed by notes on nutraceuticals and common herbal medicines that have therapeutic potential by enhancing the patient’s immune response. Special topics such as COVID-19 risk factors and Indian traditional medicines are also included to supplement the contents. The editors have taken advantage of the vast body of knowledge accumulated since the start of the COVID-19 pandemic in 2019.
Herbal cosmetics
What are cosmetics? Cosmetics are products applied to any part of human body for cleansing, beautifying, attractiveness and altering the appearance. Today cosmetics are considered a necessity and not a luxury. What are herbal cosmetics? Herbal cosmetics defined as the beauty products posses desirable physiological activities, such as skin healing, smoothening, appearance. These are the cosmetics which are prepared by using plant products having cosmetic actions Herbal drugs traditionally used in medicine and skin care consist of herbs and spices from higher plants, thalli from lower botanical organisms, microbial biomasses, and the various extracts that can be obtained from these sources.
Herbal bioactive-based drug delivery systems ; 1st ed.
Provides a wide-ranging, in-depth resource for herbal bioactives, including detailed discussion of standardization and regulations. The book first explores specific drug delivery systems such as gastrointestinal, ocular, pulmonary, transdermal, and vaginal and rectal. It then discusses novel applications for nano, cosmetics, nutraceuticals, wound healing and cancer treatment. Finally, there is a section focusing on standardization and regulation which includes an enhancement of properties. This book is an essential resource for pharmacologists, pharmaceutical scientists, material scientists, botanists, and all those interested in natural products and drug delivery systems developments.
