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Cancer Informatics in the Post Genomic Era : Toward Information-Based Medicine
Medical information science requires analytic tools. This is achieved by developing and assessing methods and systems for the acquisition, processing, and interpretation of patient data, aided by scientific discovery. Cancer Informatics in Post-Genomic Era provides both the necessary methodology and practical information tools.Key challenges include integrating research and clinical care, sharing data, and establishing partnerships within and across sectors of patient diagnosis and treatment.Addressing important clinical questions in cancer research will benefit from expanding computational biology.
Apoptosis, cell signaling, and human diseases : Molecular mechanisms ; Vol.2
Volume 1 is divided into two sections: "Malignant Transformation and Metastasis" and "Molecular Basis of Disease Therapy." Volume 2 follows a similar structure and is divided into sections entitled "Kinases and Phosphate" and "Molecular Basis of Cell Death." All of the contributors are at the forefront of scientific discovery, and the reviews they present systemically examine the most exciting and innovative aspects of their particular areas of expertise. Researchers will find these volumes of major benefit as they search for novel and more effective treatments for human diseases.
Apoptosis, cell signaling, and human diseases : Molecular mechanisms ; Vol.1
Volume 1 is divided into two sections: “Malignant Transformation and Metastasis” and “Molecular Basis of Disease Therapy.” Volume 2 follows a similar structure and is divided into sections entitled “Kinases and Phosphate” and “Molecular Basis of Cell Death.” All of the contributors are at the forefront of scientific discovery, and the reviews they present systemically examine the most exciting and innovative aspects of their particular areas of expertise. Researchers will find these volumes of major benefit as they search for novel and more effective treatments for human diseases.
Ageing : The Paradox of Life : Why We Age
For centuries people have been puzzled by the inevitability of human aging. For most of the second half of the twentieth century aging remained a mystery, or an unsolved biological problem. At the end of the 20th century a remarkable scientific discovery emerged. It was not a single discovery in the usual sense, because it was based on a series of important interconnected insights over quite a long period of time. These insights made it possible for the very first time to understand the biological reasons for aging in animals and man. It can already be said, however, that the many observations and insights that explain aging will not be accepted as established knowledge for a long time.
Ambient intelligence for scientific discovery : Foundations, theories, and systems
Many difficult scientific discovery tasks can only be solved in interactive ways, by combining intelligent computing techniques with intuitive and adaptive user interfaces. It is inevitable to use human intelligence in scientific discovery systems: human eyes can capture complex patterns and relationships, along with detecting the exceptional cases in a data set; the human brain can easily manipulate perceptions to make decisions. Ambient intelligence is about this kind of ubiquitous and autonomous human interaction with information. Scientific discovery is a process of creative perception and communication, dealing with questions like: how do we significantly reduce information while maintaining meaning, or how do we extract patterns from massive data and growing data resources. Originating from the SIGCHI Workshop on Ambient Intelligence for Scientific Discovery, this state-of-the-art survey is organized in three parts: new paradigms in scientific discovery, ambient cognition, and ambient intelligence systems. Many chapters share common features such as interaction, vision, language, and biomedicine.
Making Ammonia : Fritz Haber, Walther Nernst, and the Nature of Scientific Discovery
This book discusses the progress of science and the transfer of scientific knowledge to technological application. It also identifies the factors necessary to achieve this progress. Based on a case study of the physical chemist Fritz Haber's discovery of ammonia synthesis between 1903 and 1909, the book places Haber's work in historical and scientific (physicochemical) context. The scientific developments of the preceding century are framed in a way that emphasizes the confluence of knowledge needed for Haber's success. Against this background, Haber's work is presented in detail along with the indispensable contributions of his colleague, the physical chemist, Walter Nernst, and their assistants. The detailed accounts of scientific advancement remind us of the physical basis on which our scientific theories and ideas are built. Without this reminder we often forget how complex, and how beautiful achievements in science can be.
