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Les douleurs abdominales en questions : Rôle physiopathologique de la sensibilité viscérale = Abdominal pain in question : The pathophysiological role of visceral sensitivity
The gut-brain axis refers to the network of nerve pathways that connect the myenteric plexus, the veritable "gut brain," to the central nervous system. Nearly 80% of these neurons are sensory neurons, and the afferent pathways that transmit information from the digestive tract to the central nervous system play a crucial role in the physiological regulation of digestive functions, as well as in certain pathological conditions. A large majority of these sensations remain unconscious and give rise to reflex responses. Only those requiring a conscious response reach the level of awareness in a normal state (hunger, thirst, the urge to defecate). In pathological situations, the same is true for painful sensations of digestive origin. Functional bowel disorders are a frequent reason for consultation. Their pathophysiology is now based on a model integrating the various etiological factors around the brain-gut axis. These patients frequently present with visceral hypersensitivity, which manifests as an increased perception of digestive sensations, notably the onset of pain in response to stimuli that are not painful in normal subjects. Recognizing the role of visceral hypersensitivity has made it possible to explain the mechanism of action of medications used to treat functional bowel disorders and paves the way for the development of new molecules acting on digestive afferents. In this book, we will describe the anatomical and physiological basis for understanding the concept of visceral sensitivity and the role of digestive afferents in the pathophysiology of acute and chronic abdominal pain, particularly irritable bowel syndrome.
La lombalgie en 2007 : Aspects pratiques = Low back pain in 2007 : Practical aspects
Low back pain is one of the main reasons for consultation, whether in general or specialized medicine. It poses a real public health problem. This "back pain", which can despair patients and doctors by its sometimes rebellious character, explains the multiplicity of examinations sometimes practiced and the treatments implemented. This work is a collection of the most recent developments in terms of physiopathological knowledge of disc involvement, clinical examination and the place of surgery and in particular disc prostheses. An update concerns the indications and contributions of additional examinations; some formidable diagnostic traps are mentioned. Medical treatments such as infiltrations, manipulations, the benefit of restraints and the provision of acupuncture are being developed. Also discussed are the latest scientific data on isokinetic evaluation and retraining, as well as the role of sports activity as a factor in the prevention or aggravation of low back pain. Finally, the medico-legal aspect is dealt with in the context of work accidents, and the assessment after trauma. This book is the result of the collaboration and experience of undisputed specialists in this field.
Community pharmacy : symptoms, diagnosis and treatment
Support pharmacists in identifying, diagnosing, treating or referring the illnesses and conditions they will commonly encounter in the community. A logical structure covers the full range of common presentations, including respiratory, ear, eye, gastroenterological and skin conditions. Clear pictures, referral criteria and summaries of treatment options support clinical reasoning, differential diagnosis and selection of appropriate products. Suitable for both pharmacy students and qualified pharmacists, the sixth edition has been fully updated to align with changes to the pharmacy curriculum and the rapidly expanding scope of pharmacists working in primary care and community pharmacy.
Classic Papers in Critical Care
Every medical specialty has at its basis a core of classic papers, which both reflect the historical background and give insight into present and future developments. The papers discussed in this book are considered classics for many reasons, but in all cases they highlight landmarks in the development in critical care medicine and therefore providing an invaluable reference for both trainee and practising clinicians.
Bone Marrow Derived Progenitors
The ability of stem cells to acquire different desired phenotypes has opened the door for a new discipline: regenerative medicine. Much of the interest for this purpose is generated by embryonic stem cells, but their use is still controversial for moral reasons as well as scientifically. Less controversial and readily available are the adult bone marrow-derived progenitors including hematopoietic stem cells, endothelial progenitors and mesenchymal stem cells. The ambitious goal of this volume is to provide a comprehensive overview of the currently available information related to the therapeutic utility of adult bone marrow-derived cells. Each chapter has been written by an accomplished expert in the field, making this a hugely valuable resource for anyone looking for an up-to-the-minute assessment of current practice in adult bone marrow-derived cell therapy.
Bioethics in Law
The idea for Bioethics in Law began more than a decade ago, while I was studying social science and law. I was parti- larly interested in the collaborations that comprised social s- ence in law. Economic and social data in the pioneering Brandeis brief had been used to defend an early 20th-century labor law; surveys of consumer confusion had helped resolve trademark - fringement cases; psychologists’ predictions of future violence had informed capital sentencing decisions. Additionally, Kenneth Clark’s “doll studies,” cited by the Supreme Court in Brown v. Board of Education, had helped change the course of American 1 history.
Axonal branching and recovery of coordinated muscle activity after transsection of the facial nerve in adult rats
Facial nerve surgery inevitably leads to partial pareses, abnormally associated movements and pathologically altered reflexes. The reason for this "post-paralytic syndrome" is the misdirected reinnervation of targets
Applied Peritoneal Dialysis : Improving Patient Outcomes
This book offers a comprehensive guide to peritoneal dialysis (PD). Home dialysis, and more specifically PD, is growing in popularity in the US. By conservative estimates, experts suggest that 45 percent of dialysis patients in the US can be on home dialysis. However, the current penetration rate is only 10 percent. This is changing with an expected major increase in the next 5 years. One of the reasons for the low uptake is that many nephrologists lack comfort and confidence in using PD as a dialysis modality.
Ageing : The Paradox of Life : Why We Age
For centuries people have been puzzled by the inevitability of human aging. For most of the second half of the twentieth century aging remained a mystery, or an unsolved biological problem. At the end of the 20th century a remarkable scientific discovery emerged. It was not a single discovery in the usual sense, because it was based on a series of important interconnected insights over quite a long period of time. These insights made it possible for the very first time to understand the biological reasons for aging in animals and man. It can already be said, however, that the many observations and insights that explain aging will not be accepted as established knowledge for a long time.
Abiotic Stress Tolerance in Plants : Toward the Improvement of Global Environment and Food
Stresses in plants caused by salt, drought, temperature, oxygen, and toxic compounds are the principal reason for reduction in crop yield. For example, high salinity in soils accounts for large decline in the yield of a wide variety of crops world over; ~1000 million ha of land is affected by soil salinity. Increased sunlight leads to the generation of reactive oxygen species, which damage the plant cells. The threat of global environment change makes it increasingly demanding to generate crop plants that could withstand such harsh conditions. Much progress has been made in the identification and characterization of the mechanisms that allow plants to tolerate abiotic stresses.
A History of Limb Amputation
This book traces humanity’s long experience of natural amputations due to congenital absence, disease, frostbite, toxins, domestic and wild animal trauma, and for non-medical reasons related to punitive, ritual, and legal actions, ultimately leading to the development of elective surgical amputation. While the evolution of surgical techniques forms a major chapter in the book, many ancillary problems are addressed including the control of hemorrhage and infection, the approach to pain relief, the development of suitable instruments and equipment, and the invention of prostheses, all suitably illuminated with case histories and relevant illustrations. In addition, alternative procedures designed to avoid amputation, increasingly important in the last two centuries, are debated, and factors associated with self-amputation in extremis, not rare according to press reports, are also examined. A separate chapter considers the philosophy and interpretations of society, patients, and surgeons faced with amputation, particularly before anesthesia.
Judges and Adjudication in Constitutional Democracies : A View from Legal Realism
Offers contributions to a philosophical and realistic approach to the place of adjudication in contemporary constitutional democracies. Bringing together scholars from different legal and philosophical backgrounds, purports to cast light on the role(s) of judges and the function of judicial interpretation inside of constitutional states, from the standpoint of legal realism as a revisited and sophisticated jurisprudential outlook. In so doing, also copes with a few major jurisprudential issues, like, e.g., determining the ideas that make up the core of legal realism, exploring the relation between legal realism and legal positivism, identifying the boundaries of judicial interpretation as they appear from a realist standpoint, as well as considering some skeptical outlooks on the very claims of contemporary legal realism.
Artificial intelligence and legal analytics : new tools for law practice in the digital age
The field of artificial intelligence (AI) and the law is on the cusp of a revolution. This book - designed to explain computational processes to non-programmers - describes how text analytic programs will change the practice of law, specifically by connecting computational models of legal reasoning directly with legal text.
Machine learning for biomedical application
Biomedicine is a multidisciplinary branch of medical science that consists of many scientific disciplines, e.g., biology, biotechnology, bioinformatics, and genetics; moreover, it covers various medical specialties. In recent years, this field of science has developed rapidly. This means that a large amount of data has been generated, due to (among other reasons) the processing, analysis, and recognition of a wide range of biomedical signals and images obtained through increasingly advanced medical imaging devices. The analysis of these data requires the use of advanced IT methods, which include those related to the use of artificial intelligence, and in particular machine learning. It is a summary of the Special Issue “Machine Learning for Biomedical Application”, briefly outlining selected applications of machine learning in the processing, analysis, and recognition of biomedical data, mostly regarding biosignals and medical images.
Machine Learning and Cognitive Computing for Mobile Communications and Wireless Networks
Communication and network technology has witnessed recent rapid development and numerous information services and applications have been developed globally. These technologies have high impact on society and the way people are leading their lives. The advancement in technology has undoubtedly improved the quality of service and user experience yet a lot needs to be still done. Some areas that still need improvement include seamless wide-area coverage, high-capacity hot-spots, low-power massive-connections, low-latency and high-reliability and so on. Thus, it is highly desirable to develop smart technologies for communication to improve the overall services and management of wireless communication. Machine learning and cognitive computing have converged to give some groundbreaking solutions for smart machines. With these two technologies coming together, the machines can acquire the ability to reason similar to the human brain. The research area of machine learning and cognitive computing cover many fields like psychology, biology, signal processing, physics, information theory, mathematics, and statistics that can be used effectively for topology management. Therefore, the utilization of machine learning techniques like data analytics and cognitive power will lead to better performance of communication and wireless systems.
Machine Ethics : From Machine Morals to the Machinery of Morality
Offers the first systematic guide to machine ethics, bridging between computer science, social sciences and philosophy. Based on a dialogue between an AI scientist and a novelist philosopher, the book discusses important findings on which moral values machines can be taught and how. In turn, it investigates what kind of artificial intelligence (AI) people do actually want.
Logical Aspects of Computational Linguistics ; 5th International Conference, LACL 2005, Bordeaux, France, April 28-30, 2005, Proceedings
Inaugurates the new FoLLI LNAI subline. It constitutes the refereed proceedings of the 5th International Conference on Logical Aspects of Computational Linguistics, LACL 2005, held in Bordeaux, France in April 2005. The 25 revised full papers presented were carefully reviewed and selected from over 40 submissions. The papers address a wide range of logical and formal methods in computational linguistics with studies of particular grammar formalisms and their computational properties, language engineering, and traditional topics about the syntax/semantics interface.
Journal on Data Semantics XI
The LNCS Journal on Data Semantics is devoted to the presentation of notable work that, in one way or another, addresses research and development on issues related to data semantics. The scope of the journal ranges from theories supporting the formal definition of semantic content to innovative domain-specific applications of semantic knowledge. The journal addresses researchers and advanced practitioners working on the semantic web, interoperability, mobile information services, data warehousing, knowledge representation and reasoning, conceptual database modeling, ontologies, and artificial intelligence.
Journal on Data Semantics VIII
Springer's LNCS Journal on Data Semantics aims at providing a highly visible dissemination channel for most remarkable work that in one way or another addresses research and development on issues related to the semantics of data. The target domain ranges from theories supporting the formal definition of semantic content to innovative domain-specific application of semantic knowledge. This publication channel should be of the highest interest to researchers and advanced practitioners working on the Semantic Web, interoperability, mobile information services, data warehousing, knowledge representation and reasoning, conceptual database modeling, ontologies, and artificial intelligence.
Journal on Data Semantics VII
The LNCS Journal on Data Semantics is devoted to the presentation of notable work that, in one way or another, addresses research and development on issues related to data semantics. Based on the highly visible publication platform Lecture Notes in Computer Science, this new journal is widely disseminated and available worldwide. The scope of the journal ranges from theories supporting the formal definition of semantic content to innovative domain-specific applications of semantic knowledge. The journal addresses researchers and advanced practitioners working on the semantic web, interoperability, mobile information services, data warehousing, knowledge representation and reasoning, conceptual database modeling, ontologies, and artificial intelligence.
