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Management of Early Stage Breast Cancer : Basics and Controversies
Breast cancer, its causes, early detection and treatment have received considerable attention, since this widespread disease is one of the most important health concerns for women. This book provides a comprehensive overview of the diagnostic and therapeutic aspects of the management of early-stage breast cancer, including essential information on basic topics like pathology, and radiology, as well as the latest developments. Further, it discusses all aspects of surgical care, chemotherapy and radiation therapy, together with the controversies and current management guidelines.
Liver Radioembolization with Y90 Microspheres
Provides an in-depth account of all aspects of radioembolization, a relatively novel technique based on the efficacy of radiotherapy for the treatment of liver tumors.
Les cancers ovariens = Ovarian cancers
Deals with ovarian cancers and their therapeutic management. Besides the epithelial tumors which are the most frequent, the rarer tumors, with attenuated malignancy, germ cells or of the ovarian stroma are also studied. Specialists from multiple backgrounds each deliver in their field the most recent knowledge on the fundamental aspects of the disease, its genetic, epidemiological and prognostic characteristics and its pathological peculiarities. Modern means of diagnosis are presented. The surgical technique, including laparoscopy, is detailed at the different stages of the disease. The therapeutic strategy aims to position the surgery and chemotherapy according to the stage. The current place of radiotherapy and isotopic therapies is indicated. Some more specific aspects are discussed, screening, lymph node dissection, the “second look”, intraperitoneal chemotherapy with or without hyperthermia, treatment of the elderly, monitoring after treatment… as well as the emergence of targeted therapies.
Le cancer du sein = Breast cancer
The reader will find there both a synthetic summary of the current state of knowledge of epidemiology, risk factors and pathological aspects as well as a presentation of the surgical aspects, in particular, of the new approach that constitutes the sentinel node procedure. Radiotherapy, in a practical view, is divided into essential clinical questions. The medical treatment is then discussed according to the different situations encountered on a daily basis. Particular attention is of course paid to recent data both with the contribution of hormone therapy and targeted therapies. Finally, the symptomatic treatments and especially the psychological care of these patients are not forgotten.
Late Effects of Cancer Treatment on Normal Tissues
Based on the LENT V NCI-sponsored meeting held in May 2004 and the CURED I conference held in 2006. It addresses a number of critical topics relating to late effects, such as mechanisms of injury, the role of screening, options for interventions, second malignancies, and prevention.
Chirurgie oncoplastique et reconstruction dans le cancer du sein: Techniques et indications L’expérience de l’Institut Curie = Oncoplastic surgery and reconstruction in breast cancer: Techniques and indications The Institut Curie experience
This book is the application of plastic surgery techniques to cancer situations that is called "oncoplastic" surgery. The Institut Curie team takes stock of these techniques and indications applied in 2007 in France.
Cancer Neurology in Clinical Practice : Neurologic Complications of Cancer and Its Treatment
This book gives a comprehensive analysis of how cancer affects the nervous system, It encompasses the experience of senior physicians actively engaged in neuro-oncology centers throughout the world.
Cancer du testicule = Testicular cancer
Testicular cancer has benefited from important therapeutic advances radically transforming its prognosis. Recent protocols have led to the development of treatments that maintain therapeutic efficacy while favoring quality of life and minimizing the sequelae (such as fertility disorders) in these often young men. This book discusses the various technical advances both in the field of diagnosis - with the contribution of modern imaging and anatomopathology - and therapy. The place of chemotherapy as well as that of surgery are largely detailed, thus placing the urologist at the heart of the multidisciplinary team taking care of these patients. Quality of life is also discussed by taking into account the impact of the treatment of these tumors on the fertility of these young patients.
Cancer du sujet âgé = Cancer in the elderly
Etablir un diagnostic précoce, définir une stratégie adaptée et offrir une meilleure qualité de vie chez le sujet âgé atteint de cancer constituent les défis de l’Oncologie de ce début de siècle. Cet ouvrage a pour objectif de proposer aux médecins et aux étudiants un condensé des différents aspects de l’oncologie sur le sujet âgé. Dans une première partie, les aspects épidémiologiques et biologiques ainsi que l’évaluation gériatrique multiparamétrique sont abordés. Les particularités de l’application de la chimiothérapie, de la radiothérapie et de la chirurgie au sujet âgé sont passées en revue. Dans une troisième partie, la stratégie thérapeutique multidisciplinaire est ensuite détaillée par site.
Cancer du sein avancé : 29es Journées de la Société Française de Sénologie et Pathologie Mammaire (SFSPM) Avignon, 14–16 novembre 2007 = Advanced breast cancer : 29th Days of the French Society of Senology and Breast Pathology (SFSPM) Avignon, November 14–16, 2007
These days are an opportunity to remind and persuade those less convinced that the treatment of this very particular phase of the disease is not limited to a score played by a few speakers or even by medical oncologists alone; but on the contrary, we must bring into play a truly philharmonic polyphonic ensemble, united around the patient and comprising all the players in multidisciplinary care: general practitioner, surgeon, radiotherapist, imaging specialist, gynecologist, general practitioner, psychologist, algologist, supportive care workers ...
Breast cancer research and treatment : innovative concepts
Focuses on innovative treatment options for breast cancer, including surgery, radiotherapy, systemic therapy and of course immunotherapy that is changing outcomes in some aggressive breast cancer histotypes. Subsequent chapters also address the ongoing emerging research in the screening, diagnostics, and management of all subtypes of breast cancers. All current landscapes and future perspectives in each molecular subtype: luminal, HER2-positive, and triple-negative breast cancers are discussed within the different chapters. Breast cancer is still the most common cancer and cause of cancer deaths among women worldwide. The improvement of breast cancer outcome appears to be strictly related to the validation of precise biomarkers that enable us to better select personalized approaches in breast cancer management. The closing chapters deal with the challenges of low income countries of conducting research in the era of precision medicine for cancer. The book is edited and authored by leading experts in this field and will be of interest for clinicians and scientists alike
Antiangiogenic Agents in Cancer Therapy
Antiangiogenesis remains a dynamic and evolving field in oncology. New therapeutic targets continue to emerge followed by the rapid development of new therapeutic agents to be investigated in clinical trials. Optimizing the therapeutic potential of antiangiogenic agents in combination with the other therapies in the armamentarium to fight cancer will be an on-going challenge. Antiangiogenic Agents in Cancer Therapy, Second Edition provides a current, up-dated perspective on the state of the art of angiogenesis and therapy with a compendium of scientific findings and approaches to the study of angiogenesis in cancer. Leaders in the field present chapters on such topics as the environmental influences and the genetic and physiologic abnormalities that mediate angiogenesis and its role in the progression of malignant disease, working models of tumor angiogenesis, and the role of angiogenesis inhibition in the therapy of malignant disease in humans. Comprehensive and cutting-edge, Antiangiogenic Agents in Cancer Therapy, Second Edition is an ideal, valuable guide to the most recent advances in the field, and a collection that will be useful for many years to come.
Advances in Radiation Oncology in Lung Cancer
This volume is unique in being devoted solely to the radiation oncology of lung cancer, and will be of great value to all who are involved in the diagnosis and treatment of the disease. Both non-small cell and small cell lung cancer are considered in detail. Current state of the art treatment strategies and novel approaches that promise further improvements in outcome are explained and evaluated, with the aid of high-quality illustrations. Treatment-related toxicity is discussed, and further individual chapters focus on topics such as quality of life studies, prognostic factors and pitfalls in the design and analysis of clinical trials.
Accelerated Partial Breast Irradiation : Techniques and Clinical Implementation
Accelerated partial breast irradiation (APBI) is being rapidly introduced into the clinical management of early breast cancer. APBI, in fact, encompasses a number of different techniques and approaches that include brachytherapy, intraoperative, and external beam techniques. There is currently no single source that describes these techniques and their clinical implementation. This text will be a concise handbook designed to assist the clinician in the implementation of APBI.
Machine learning for biomedical application
Biomedicine is a multidisciplinary branch of medical science that consists of many scientific disciplines, e.g., biology, biotechnology, bioinformatics, and genetics; moreover, it covers various medical specialties. In recent years, this field of science has developed rapidly. This means that a large amount of data has been generated, due to (among other reasons) the processing, analysis, and recognition of a wide range of biomedical signals and images obtained through increasingly advanced medical imaging devices. The analysis of these data requires the use of advanced IT methods, which include those related to the use of artificial intelligence, and in particular machine learning. It is a summary of the Special Issue “Machine Learning for Biomedical Application”, briefly outlining selected applications of machine learning in the processing, analysis, and recognition of biomedical data, mostly regarding biosignals and medical images.
Care of head and neck cancer patients for dental hygienists and dental therapists
An advisory guide that enables dental hygienists, dental therapists, and other health care professionals to appreciate the journey undertaken by head and neck cancer patients. Focusing on the before, during, and after treatments, the book covers common head and neck cancer treatments such as surgery, radiotherapy, chemotherapy and innovative new therapies. It also discusses treatment complications such as halitosis, osteoradionecrosis, and radiation dermatitis.
Adaptive Scalarization Methods in Multiobjective Optimization
This book presents new adaptive solution methods for multiobjective optimization problems based on parameter dependent scalarizations. With the help of sensitivity results an adaptive parameter control is developed so that high-quality approximations of the efficient set are generated. These examinations are based on a general scalarization approach for arbitrary partial orderings defined by a closed pointed convex cone in the objective space. The application of the results to many other well-known scalarization methods is also presented. Background material of multiobjective optimization and scalarization approaches is concisely summarized at the beginning. The effectiveness of these new methods is demonstrated by test problems and a recent problem in intensity-modulated radiotherapy. The book concludes with a further application: a procedure for solving multiobjective bilevel optimization problems.
