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Mammalian and Avian Transgenesis : New Approaches

Mammalian and Avian Transgenesis presents a collection of novel methods for the production of a wide range of transgenic animals. The manual focuses largely on mice, but also contains protocols for successful transgenesis in rats, cows, pigs and birds. The manual provides detailed, step-by-step protocols covering all aspects of the production of transgenic animals, including the use of lentiviral vectors in gene transfer, intracytoplasmic sperm injection, nuclear transfer, large insert transgenesis, conditional gene expression systems, the use of reporter genes in transgenesis and transgenesis in large animals and birds. The text is supplemented by superb color photos. While the focus is on newly established techniques, the fundamental methods of transgenesis are also covered for those new to the field. Thus this manual is perfectly suited for those wishing to adopt new technologies in transgenesis.

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Les techniques de monitorage hémodynamique en réanimation = Hemodynamic monitoring techniques in intensive care

The hemodynamic monitoring of intensive care patients is undergoing major changes. Technological advances such as computerization and miniaturization have made it possible to considerably expand the range of assessment tools available at the bedside. Thus, the approach to cardiovascular monitoring - which was once readily "invasive" and global - is gradually becoming non-invasive and locoregional or even tissue. At the same time, the combined evolution of technology and physiological and pathophysiological concepts now provides the clinician with access to a variety of "functional hemodynamic monitoring". The aim of this book is to provide a better understanding of the interest and the limits of the hemodynamic parameters accessible by current hemodynamic monitoring techniques. It thus aims to ensure that the use of these techniques is perfectly mastered by resuscitators and anesthetists-resuscitators so that patient care is ultimately optimal.

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An introduction to pharmacovigilance ; 2nd ed.

Designed to aid the rapid understanding of the key principles of pharmacovigilance. Packed full of examples illustrating drug safety issues it not only covers the processes involved, but the regulatory aspects and ethical and societal considerations of pharmacovigilance. Covering the basics step-by-step, this book is perfect for beginners and is essential reading for those new to drug safety departments and pharmaceutical medicine students. The second edition is thoroughly revised and updated throughout and includes a new chapter on clinical aspects of pharmacovigilance.

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Abnormal Skeletal Phenotypes : From Simple Signs to Complex Diagnoses

This book focuses on the radiographic changes of malformation syndromes and skeletal dysplasias. It is structured such that the reader can identify the radiographic changes and relate them to specific disease entities. The aim is to provide an essential, practical guideline to the recognition of the key radiographic signs for diagnosing malformation syndromes and skeletal dysplasias.

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JDBC Metadata, MySQL, and Oracle Recipes : A Problem-Solution Approach

JDBC Metadata, MySQL, and Oracle Recipes is the only book that focuses on metadata or annotation-based code recipes for JDBC API for use with Oracle and MySQL. It continues where the authors other book, JDBC Recipes: A Problem-Solution Approach, leaves off. This edition is also a Java EE 5-compliant book, perfect for lightweight Java database development. And it provides cut-and-paste code templates that can be immediately customized and applied in each developer's application development.

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Beginning Ubuntu Linux : From novice to professional

Beginning Ubuntu Linux is the perfect guide for those switching to the world's favorite Linux. The new edition has been thoroughly updated to cover technology introduced in the 6.10 release. You'll learn how to install Linux, set up your hardware and software, customize the desktop experience, browse the Web and send/receive e-mail, play back audio and video, edit digital images, use the OpenOffice.org office suite, and more.

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Algorithms and data structures for massive datasets

Learn: Probabilistic sketching data structures for practical problems Choosing the right database engine for your application Evaluating and designing efficient on-disk data structures and algorithms Understanding the algorithmic trade-offs involved in massive-scale systems Deriving basic statistics from streaming data Correctly sampling streaming data Computing percentiles with limited space resources Algorithms and Data Structures for Massive Datasets reveals a toolbox of new methods that are perfect for handling modern big data applications. You'll explore the novel data structures and algorithms that underpin Google, Facebook, and other enterprise applications that work with truly massive amounts of data. These effective techniques can be applied to any discipline, from finance to text analysis. Graphics, illustrations, and hands-on industry examples make complex ideas practical to implement in your projects--and there's no mathematical proofs to puzzle over. Work through this one-of-a-kind guide, and you'll find the sweet spot of saving space without sacrificing your data's accuracy. About the Technology Standard algorithms and data structures may become slow--or fail altogether--when applied to large distributed datasets. Choosing algorithms designed for big data saves time, increases accuracy, and reduces processing cost.

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Master Dentistry ; Vol.1 : Oral and Maxillofacial Surgery, Radiology, Pathology and Oral Medicine

Provides a comprehensive overview of the oral and maxillofacial subjects in dentistry that students will need in order to pass their final exams. This invaluable adjunct to exam preparation provides a practical synthesis of core information, reflecting real-life case scenarios. Information is structured to enhance understanding and clinical decision making, and a variety of self-assessment methods prepare students for success. Comprehensively updated, the book covers a range of essential topics in the field of contemporary oral and maxillofacial subjects, including surgical flap design, state-of-the-art surgical techniques, zygomatic implants, molecular pathology, current imaging applications and pain management. The text is integrated and evidence based throughout. Covers oral and maxillofacial surgery, radiology, pathology and oral medicine subjects Brand new chapter on facial skin broadens diagnostic ability Range of self-assessment tasks to support learning Aligns to dental school curricula globally Concise and easy to follow Designed to support recall for examination purposes Practical guidance on examination preparation and skills Perfect for BDS exam preparation and candidates taking the MFDS, MJDF, ORE or other post-graduate exams

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Biological mechanisms of tooth movement ; 3rd ed.

Cover subjects such as: The development of biological concepts in orthodontics, including the cellular and molecular biology behind orthodontic tooth movement Mechanics meets biology, including the effects of mechanical loading on hard and soft tissues and cells, and biological reactions to temporary anchorage devices Inflammation and orthodontics, including markers for tissue remodeling in the gingival crevicular fluid and saliva Personalized diagnosis and treatment based on genomic criteria, including the genetic influences on orthodontic tooth movement Rapid orthodontics, including methods to accelerate or decelerate orthodontic tooth movement Perfect for residents and PhD students of orthodontic and periodontal programs, Biological Mechanisms of Tooth Movement is also useful to academics, clinicians, bone biologists, and researchers with an interest in the mechanics and biology of tooth movement.

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Markets, Games, and Strategic Behavior : An Introduction to Experimental Economics

This is the perfect book for any undergraduate course in experimental economics or behavioral game theory. New material on topics such as matching, belief elicitation, repeated games, prospect theory, probabilistic choice, macro experiments, and statistical analysis Participatory experiments that connect behavioral theory and laboratory research Largely self-contained chapters that can each be covered in a single class Guidance for instructors on setting up classroom experiments, with either hand-run procedures or free online software End-of-chapter problems, including some conceptual-design questions, with hints or partial solutions provided

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Learning in Economic Systems with Expectations Feedback

Recently economists have more and more focussed on scenarios in which agents' views of the world may be erroneous. These notes introduce the concept of perfect forecasting rules which provide best least-squares predictions along the evolution of an economic system.

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Cartooning made easy : Circle, triangle, square : Draw unique cartoon characters using simple geometric shapes

offers easy-to-follow instruction for using basic shapes to draw cute cartoon characters. Her approach is simple: All you need are basic drawing tools and shapes to cartoon! The book features dozens of drawing projects and step-by-step instruction perfect for beginning and aspiring artists, cartoonists, illustrators, pen and graphite artists, and many others. Each project combines simple geometric shapes—including circles and triangles and squares but also ovals, rectangles, and more—to draw adorable, cartoon-inspired artwork, including cartoon: Heads / Faces / Bodies / Unique characters / Animals, such as elephants / And more!

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Lifting Modules : Supplements and Projectivity in Module Theory

Extending modules are generalizations of injective modules and, dually, lifting modules generalize projective supplemented modules. There is a certain asymmetry in this duality. While the theory of extending modules is well documented in monographs and text books, the purpose of our monograph is to provide a thorough study of supplements and projectivity conditions needed to investigate classes of modules related to lifting modules. The text begins with an introduction to small submodules, the radical, variations on projectivity, and hollow dimension. The subsequent chapters consider preradicals and torsion theories (in particular related to small modules), decompositions of modules (including the exchange property and local semi-T-nilpotency), supplements in modules (with specific emphasis on semilocal endomorphism rings), finishing with a long chapter on lifting modules, leading up their use in the theory of perfect rings, Harada rings, and quasi-Frobenius rings.

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Lenses and Waves : Christiaan Huygens and the Mathematical Science of Optics in the Seventeenth Century

this book offers the first account of the development of Huygens’ mathematical analysis of lenses and telescopes and its significance for the origin of the wave theory of light. As Huygens applied his mathematical proficiency to practical issues pertaining to telescopes – including trying to design a perfect telescope by means of mathematical theory – his dioptrics is significant for our understanding of seventeenth-century relations between theory and practice. With this full account of Huygens’ optics, this book sheds new light on the history of seventeenth-century optics and the rise of the new mathematical sciences, as well as Huygens’ oeuvre as a whole. Students of the history of optics, of early mathematical physics, and the Scientific Revolution, will find this book enlightening.

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Charged Particle Traps : Physics and Techniques of Charged Particle Field Confinement

This book provides an introduction and guide to modern advances in charged particle (and antiparticle) confinement by electromagnetic fields. Confinement in different trap geometries, the influence of trap imperfections, classical and quantum mechanical description of the trapped particle motion, different methods of ion cooling to low temperatures, and non-neutral plasma properties (including Coulomb crystals) are the main subjects. They form the basis of such applications of charged particle traps as high-resolution optical and microwave spectroscopy, mass spectrometry, atomic clocks, and, potentially, quantum computing.

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Balkan Sprachbund Morpho-Syntactic Features

This book discusses the morpho-syntactic Balkan Sprachbund features in nine languages in which they are most numerous. It contains a wealth of Balkan linguistic material, collected from both the existing literature sources and from the author’s own field work.

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Algebraic Groups and Lie Groups with Few Factors

Algebraic groups are treated in this volume from a group theoretical point of view and the obtained results are compared with the analogous issues in the theory of Lie groups. The main body of the text is devoted to a classification of algebraic groups and Lie groups having only few subgroups or few factor groups of different type. In particular, the diversity of the nature of algebraic groups over fields of positive characteristic and over fields of characteristic zero is emphasized. This is revealed by the plethora of three-dimensional unipotent algebraic groups over a perfect field of positive characteristic, as well as, by many concrete examples which cover an area systematically. In the final section, algebraic groups and Lie groups having many closed normal subgroups are determined.

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Advanced Magnetic Nanostructures

Advanced Magnetic Nanostructures is devoted to the fabrication, characterization, experimental investigation, theoretical understanding, and utilization of advanced magnetic nanostructures. Focus is on various types of 'bottom-up' and 'top-down' artificial nanostructures, as contrasted to naturally occurring magnetic nanostructures, such as iron-oxide inclusions in magnetic rocks, and to structures such as perfect thin films. Industrial and academic researchers in magnetism and related areas such as nanotechnology, materials science, and theoretical solid-state physics will find this book a valuable resource.

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