Refine Results
Sort By
From
To
Page 1
Page 1
Manual of intracytoplasmic sperm injection in human assisted reproduction
For around half of the couples who have trouble conceiving the cause of infertility is sperm-related. Intracytoplasmic sperm injection (ICSI) is the most common and successful treatment for male infertility. Here, the pioneers for the technique, along with authorities in the field, describe the underlying science of ICSI and other micromanipulation techniques. Practical advice for performing the techniques is covered in depth, including sperm selection, laser-assisted ICSI, and the use of piezo in ICSI. Examining the safety of ICSI in animal models as well as the impact of ICSI on the health and well-being of the children conceived through the procedure is discussed. This manual is an essential resource for clinical embryologists and laboratory personnel wishing to refine or develop techniques and improve outcomes.
Magnetic resonance angiography : techniques, indications and practical applications
The advent of contrast-enhanced MRA in the early to mid 1990s revolutionized the clinical approach to vascular imaging: an accurate non-invasive imaging modality, not requiring ionizing radiation or potentially nephrotoxic iodinated contrast media, was able to compete with the more hazardous and invasive catheter angiography. Today, MRA is a safe, easy-to-perform procedure routinely used in most imaging centers, and the continued development of faster, more powerful magnets and more effective contrast agents is increasingly helping to overcome many of the early limitations of the technique.
Machine learning for neurodegenerative disorders : advancements and applications
Explores the application of machine learning to the understanding, early diagnosis, and management of neurodegenerative disorders. With a specific focus on its role in ongoing clinical trials, the book covers essential topics such as data collection, pre-processing, feature extraction, model development, and validation techniques. It delves into the applications of neuroimaging techniques like magnetic resonance imaging (MRI), computed tomography (CT), and positron emission tomography (PET) in the diagnosis and understanding of neurodegenerative disorders. Additionally, the book examines various machine-learning algorithms employed for biomarker discovery in neurodegenerative disorders. It highlights the role of neuroinformatics and big data analysis in advancing the understanding and management of neurodegenerative disorders. Furthermore, the book reviews future prospects and presents the ethical considerations and regulatory challenges associated with implementing machine learning approaches in the diagnosis, treatment, and prevention of neurodegenerative disorders.
Lipids in Health and Disease
Lipids are functionally versatile molecules. They have evolved from relatively simple hydrocarbons that serve as depot storages of metabolites and barriers to the permeation of solutes into complex compounds that perform a variety of signalling functions in higher organisms. This volume is devoted to the polar lipids and their constituents. We have omitted the neutral lipids like fats and oils because their function is generally to act as deposits of metabolizable substrates. The sterols are also outside the scope of the present volume and the reader is referred to volume 28 of this series which is the subject of cholesterol. The polar lipids are comprised of fatty acids attached to either glycerol or sphingosine. The fatty acids themselves constitute an important reservoir of substrates for conversion into families of signalling and modulating molecules including the eicosanoids amongst which are the prostaglandins, thromboxanes and leucotrienes. The way fatty acid metabolism is regulated in the liver and how fatty acids are desaturated are subjects considered in the first part of this volume. This section also deals with the modulation of protein function and inflammation by unsaturated fatty acids and their derivatives. New insights into the role of fatty acid synthesis and eicosenoid function in tumour progression and metastasis are presented.
Le Distilbène trente ans après : Les enfants des 2èmes et 3èmes générations = Distilbene thirty years later : The children of the 2nd and 3rd generations
The various consequences on the anatomy and physiology of the female genitalia, as well as male, of children exposed in utero are reviewed. The impact on girls is greater than on boys: modification of the uterine cervix, reduction in the volume of the uterus with its consequences on fertility and the progress of pregnancies, risk of cancer of the vagina and the cervix. . The potential repercussions on the third generation are analyzed from experimental studies. Finally, the medico-legal implication is studied from the various trials that took place in the United States and from the first French trial that took place in Nanterre in November 2003. This work is the result of the collaboration of several experts recognized for their competence in this field. It will be of interest to all obstetrician gynecologists, urologists, but also public health physicians and midwives.
Complications in Gynaecological Surgery
Focusing on a range of gynecological issues, including urinary tract injury, sterilization and assisted pregnancy, as well as the application of cutting-edge laparoscopy, this book will be of great interest and use to the practicing gynecologist or urologist.
Complement and Kidney Disease
It is evident that a defective or deregulated complement system results in kidney diseases. An important role of complement effector and regulatory proteins in pathological settings of the kidney has been demonstrated. A large panel of distinct human kidney diseases is caused by defective complement control. Genetic analyses have identified mutations in complement regulators that are associated with these diseases. Mutations have been identified in the fluid phase alternative pathway regulator Factor H and the membrane regulator Membrane Cofactor Protein MCP (CD46). The functional characterization of the mutant proteins allows to define the pathophysiological events on a molecular level. These new concepts and data on disease mechanisms allowed establishing new diagnostic and promising therapeutic approaches for several human kidney diseases. Molecular biology, clinics and therapy are discussed in this volume.
Competence Assessment in Dementia
The increasing proportion of demented elderly in populations, debates over patient's rights and autonomy, and the growing body of knowledge on dementia has inspired the European Dementia Consensus Network to regard competence assessment in dementia as an important topic of debate.
Competence and Vulnerability in Biomedical Research
In this book, the author develops a novel justificatory framework for making judgments of decisional competence to consent to biomedical research with reference to five groups of cognitively vulnerable individuals - older children and adolescents, adults with intellectual disabilities, adults with depression, adults with schizophrenia and adults with dementia, including Alzheimer’s disease.
Comparative Placentation : Structures, Functions and Evolution
Science produces fascinating puzzles: why is there such a range of placental structures when other mammalian organs are so structurally uniform ? Why and how did the different placental structures evolve ? Comparative placental studies can facilitate the identification of the common factors in placental growth, differentiation and function and their relevance to possible evolutionary pathways. Comparative Placentation is the only book presenting up-to-date data illustrating the great variety of structure but uniform function of vertebrate placentas from fish to man. This information is essential for selection of suitable models to investigate particular practical problems of impaired or anomalous growth in human and animal placentation. The unique collection of the best light and electron micrographs from the last thirtyfive years which precisely illustrate the structural range in each taxon, make the book the most authoritative publication in this field and a vital source of information for anyone interested on reproductive physiology, anatomy and medicine.
Comparative genomics : Methods and protocols
Provides new and updated chapters covering computational and mathematical techniques and concepts related to the field of comparative genomics. The topics covered in the chapters range from those that address general techniques and concepts that apply to all organisms to others that are specialized and apply to specific biological systems such as viruses, bacteria, nematodes, and insects.
Common Eye Diseases and their Management
There have been significant advances in the diagnosis and management of eye disease since the last edition of Common Eye Diseases and their Management was published. The specialty has developed more subspecialties, and the referring doctor has to have a good knowledge of these in order to make appropriate referrals. An increased emphasis on screening has made it necessary for the primary care doctor to have a basic knowledge of eye diseases. This applies particularly to glaucoma and diabetic eye disease. The management of eye conditions in the elderly is also an important and increasing primary care problem.
Common Chinese materia medica ; Vol.2
Contains 231 species of 40 families of medicinal plants. The most important family of which are Magnoliaceae, such as Magnolia officinalis and Magnolia officinalis subsp. biloba; Schisandra chinensis of Schisandraceae; Cinnamomum aromaticum of Lauraceae, Coptis chinensis Franch., Coptis omeiensis and Coptis teeta of Berberidaceae; Isatis indigotica, Lepidium apetalum and Raphanus sativus of Cruciferae; Rheum palmatum, Rheum officinale and Rheum taguticum of Polygonaceae, etc. In each specie, it introduces the scientific names, herbal medicine names, characteristics, habitats, distributions, Acquisition and processing methods, medicinal traits, tastes, functions, use and dosages, and other information of medicinal plants, and attaches unedited color pictures and pictures of part herbal medicines for each species. This book series has totally 10 volumes, which covers 2000 kinds of Chinese medicines that are commonly seen or used. These volumes not only introduce the efficacy, function and some prescriptions of the medicines, but also introduce the biological characteristics of them in detail with clear photos of the habitats, so that readers can identify them in the field. Apart from the growing environment, the books expound the distribution areas and other information to facilitate researches and other applications. The volumes are targeted at readers of general interests and it is also of high referential value for scientific researcher and teachers. It can be used as a guide to researchers, clinical doctors, and students in the department of pharmaceutics and traditional Chinese medicine.
Clinical nuclear medicine
Clinical Nuclear Medicine … focuses on the universal state of the art in both diagnostic and therapeutic radionuclide methodology. … This book is easily readable, with presentation of essential points and plentiful references, and the quality of the figures and tables is excellent. … is a useful guide to students, technologists, and practitioners in nuclear medicine and radiology, as well as to general physicians who request nuclear diagnosis or treatment. … will be a welcome contribution to the bookshelf of nuclear medicine or radiology clinics.
Clinical MR Imaging : A Practical Approach
This book offers practical guidelines for performing efficient and cost-effective MRI examinations in daily practice. The underlying idea is that, by adopting a practical protocol-based approach, the work-flow in a MRI unit can be streamlined and optimized.
Classifications and Scores of the Shoulder
This book gives a clearly structured, well-defined compendium of classifications and scores of the shoulder for use in everyday clinical life to improve and simplify the communication between physicians and physiotherapists.
Chemical Leasing Goes Global : Selling Services Instead of Barrels : A Win-Win Business Model for Environment and Industry
Chemical Leasing is an innovative business model within the sustainable management of chemicals. The economic benefit is achieved by selling chemicals services instead of increasing the sales volume. This book contains detailed descriptions and evaluations based on existing projects in Austria, Egypt, Russia and Mexico where in a broard range of sectors and companies the application of Chemical leasing was assisted. The book also contains political and scientific interpretations and analyses.
Cerebral Hemorrhage
Cerebral hemorrhage is a common and often fatal subtype of stroke. while in the past it has received relatively little attention compared to ischemic stroke, there have been major advances in our understanding of this devastating form of stroke. The papers by world experts cover the field from molecular biology to clinical trials.
Cell-Cell Channels
The biological sciences are dominated by the idea that cells are the functionally autonomous, physically separated, discrete units of life. This concept was propounded in the 19th century by discoveries of the cellular structuring of both plants and animals. Moreover, the ap parent autonomy of unicellular eukaryotes, as well as the cellular basis of the mammalian brain (an organ whose anatomy for a long while defied attempts to validate the idea of the cellular nature of its neurons), seemed to provide the final conclusive evidence for the completeness of *cell theory', a theory which has persisted in an almost dogmatic form up to the present day. However, it is very obvious that there are numerous observations which indicate that it is not the cells which serve as the basic units of biological life but that this property falls to some other, subcellular assemblage. To deal with this intricate problem concerning the fundamental unit of living matter, we proposed the so-called Cell Body concept which, in fact, devel ops an exceedingly original idea proposed by Julius Sachs at the end of the 19th century. In the case of eukaryotic cells, DNA-enriched nuclei are intimately associated with a microtubular cytoskeleton. In this configuration—as a Cell Body—these two items comprise the fundamental functional and struc tural unit of eukaryotic living matter. The Cell Body seems to be inherent to all cells in all organisms.
Cell volume and signaling
In front of you is the finished product of your work, the text of your contributions to the 2003 Dayton International Symposium on Cell Volume and Signal Transduction. As we all recall, this symposium brought together the Doyens of Cellular and Molecular Physiology as well as aspiring young investigators and students in this field.
