Animal Models of T Cell-Mediated Skin Diseases
Pharmaceutical companies are spending increasing amounts of money on drug discovery and development. Nevertheless, attrition rates in clinical development are still very high, and up to 90% of new compounds fail in clinical phase I - III trials, which is partially due to lack of clinical efficacy. This indicates a strong need for highly predictive in vitro and in vivo models. The "50th International Workshop of the Ernst Schering Research Foundation" focussed on "Animal Models of T Cell-Mediated Skin Diseases". Such animal models should have impact not only on inflammatory dermatoses but also on other inflammatory disorders due to their model character. The current volume summarises recent advances in animal research that are important for anti-inflammatory drug discovery.
Benefit/Cost-Driven Software Development : With Benefit Points and Size Points
This book presents a set of basic techniques for estimating the benefit of IT development projects and portfolios. It also offers methods for monitoring how much of that estimated benefit is being achieved during projects. Readers can then use these benefit estimates together with cost estimates to create a benefit/cost index to help them decide which functionalities to send into construction and in what order. This allows them to focus on constructing the functionality that offers the best value for money at an early stage.
Bridge design for economy and durability : Concepts for new, strengthened and replacement bridges
Describes a number of new or updated bridging concepts which were developed and successfully applied during the author's forty years of close involvement with UK and international bridge design, construction, maintenance and research. The concepts mainly apply to the small/medium span range of bridges and viaducts and contribute to one or more of the following features: design and construction economy in both time and money ease of inspection and minimum maintenance ride quality and safety good appearance strengthening when required with minimum traffic disruption
Life centered financial planning : How to deliver value that will never be undervalued
Life-Centered Financial Planning: How to Deliver Value That Will Never Be Undervalued shows financial planners and advisors how to radically improve the service they provide to their clients by tying their decisions and strategies to their clients’ life events, stages, and goals.
Building a Cashless Society : The Swedish Route to the Future of Cash Payments
This book tells the story of how Sweden is becoming a virtually cashless society. Its goal is to improve readers’ understanding of what is driving this transition, and of the factors that are fostering and hampering it. In doing so, the book covers the role of central banks, political factors, needs for innovation, and the stakeholders involved in developing a cashless ecosystem. Adopting a historical standpoint, and drawing on a unique dataset, it presents an academic perspective on Sweden’s leading role in this global trend. The global interest in the future of cash payments makes the Swedish case particularly interesting. As a country that is close to becoming a cashless economy, it offers a role model for many other countries to learn from - whether they want to stimulate or reduce the use of cash. This highly topical book will be of interest to politicians, researchers, businesses, financial service providers and payment service providers, as well as fintech start-ups, regulators and other authorities.
Assetization : Turning Things into Assets in Technoscientific Capitalism
In this book, scholars from a range of disciplines argue that the asset—meaning anything that can be controlled, traded, and capitalized as a revenue stream—has become the primary basis of technoscientific capitalism. An asset can be an object or an experience, a sum of money or a life form, a patent or a bodily function. A process of assetization prevails, imposing investment and return as the key rationale, and overtaking commodification and its speculative logic. Although assets can be bought and sold, the point is to get a durable economic rent from them rather than make a killing on the market. Assetization examines how assets are constructed and how a variety of things can be turned into assets, analyzing the interests, activities, skills, organizations, and relations entangled in this process.
Asset prices, booms and recessions : Financial economics from a dynamic perspective
Studies the interaction of the financial market, economic activity and the macroeconomy from a dynamic perspective. The financial market to be studied here encompasses the money and bond market, credit market, stock market and foreign exchange market. Economic activity is described by the activity of firms, banks, households, governments and countries. The book shows how economic activity affects asset prices and the financial market and how asset prices and financial market volatility feed back to economic activity. The focus in this book is on theories, dynamic models and empirical evidence.
AI and the future of banking
Across its entire breadth and depth, the banking industry is at the forefront of investigating Advanced Analytics and AI technology for use in a broad range of applications, such as customer analytics and providing wealth advice for clients. AI and the Future of Banking provides new and established banking industry professionals with the essential information on the implications of data and analytics on their roles, responsibilities and personal career development.
101 Ways to Save Money on Your Tax - Legally! 2022-2023
Tax laws are constantly changing, but you don’t have to pore over piles of legislation to file your tax accurately and completely — that’s what Mr. Taxman is here for. Don’t let yourself become one of the people who overpay. Find out what you actually owe, and prepare for even better savings next year. This guide removes the stress and confusion from tax season and helps you file on time with no mistakes. Whether you're an individual, married couple,
Levity of Design : Cambridge Scholars Publishing
How can poetry embrace morality through focusing on metaphrasts? What is the relation between an allummette and the alpha rhythm? Why is it that money has turned into a metonym of goodness and success? And above all, is it still possible to think of the human subject as a viable category in late modernity? These are some of the questions that J.
Applied Physics of Carbon Nanotubes : Fundamentals of Theory, Optics and Transport Devices
The book describes the state-of-the-art in fundamental, applied and device physics of nanotubes, including fabrication, manipulation and characterization for device applications; optics of nanotubes; transport and electromechanical devices and fundamentals of theory for applications. This information is critical to the field of nanoscience since nanotubes have the potential to become a very significant electronic material for decades to come. The book will benefit all all readers interested in the application of nanotubes, either in their theoretical foundations or in newly developed characterization tools that may enable practical device fabrication.
An Introduction to the Mathematics of Money : Saving and Investing
This is an undergraduate textbook on the basic aspects of personal savings and investing with a balanced mix of mathematical rigor and economic intuition. It uses routine financial calculations as the motivation and basis for tools of elementary real analysis rather than taking the latter as given. Proofs using induction, recurrence relations and proofs by contradiction are covered. Inequalities such as the Arithmetic-Geometric Mean Inequality and the Cauchy-Schwarz Inequality are used. Basic topics in probability and statistics are presented.











