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Magnetic resonance angiography : techniques, indications and practical applications
The advent of contrast-enhanced MRA in the early to mid 1990s revolutionized the clinical approach to vascular imaging: an accurate non-invasive imaging modality, not requiring ionizing radiation or potentially nephrotoxic iodinated contrast media, was able to compete with the more hazardous and invasive catheter angiography. Today, MRA is a safe, easy-to-perform procedure routinely used in most imaging centers, and the continued development of faster, more powerful magnets and more effective contrast agents is increasingly helping to overcome many of the early limitations of the technique.
Cerebral monitoring in the OR and ICU
This comprehensive volume will serve as a complete guide to the clinical application of computer assisted systems in monitoring central nervous functions both in the OR and ICU. It presents practical guidelines and therapeutic indications for computerized EEG and Somatosensory Evoked Potential (SSEP) monitoring for the experienced user and the novice. The book also describes what cerebral monitoring can do and what its limitations are.
Cancerimmunotherapies : Solid tumors and hematologic malignancies
Presents the clinical scope of cancer immunotherapeutic agents for solid tumors and Hematologic malignancies, elaborates on the scientific details of their modes of action, and presents the impact of these agents on oncology, patients and the broader healthcare system. At present, cancer immunotherapies fall broadly into three categories: immune checkpoint inhibitors (ICIs), adoptive T cell therapies, and cancer vaccines which have distinct mechanisms of action. Immune checkpoint inhibitors rely upon disrupting tumor antigen recognition as self by the immune system through inhibition of checkpoint molecules. Adoptive T cell therapies involve the engineering of T cells ex vivo to target and destroy tumor cells. The first part of this book will provide an overview of the discovery and mechanistic details of the technology. The second part will be devoted to elaborating on the clinical outcomes, successes and limitations for specific tumor subtypes, which includes both solid tumors and hematologic malignances for both pediatric and adult populations.
Cancer Gene Therapy
the authors comprehensively review the anticancer genes and gene delivery methods currently available for cancer gene therapy, including the transfer of genetic material into the cancer cells, stimulation of the immune system to recognize and eliminate cancer cells, and the targeting of the nonmalignant stromal cells that support their growth. They also thoroughly examine the advantages and limitations of the different therapies and detail strategies to overcome obstacles to their clinical implementation
Biophysical Techniques in Photosynthesis ; Vol. II
Since the first volume on Biophysical Techniques in Photosynthesis Research, published in 1996, new experimental techniques and methods have been devised at a rapid pace. The present book is a sequel which complements the first volume (Volume 3 in the Series) by providing a comprehensive overview of the most important new techniques developed over the past ten years, especially those that are relevant for research on the mechanism and fundamental aspects of photosynthesis. The contributions are written by leading scientists in their field. The book has 5 sections: Imaging; Structure; Optical and laser spectroscopy; Magnetic resonance; Theory. Each chapter describes the basic concepts of the technique, practical applications and scientific results. Possibilities and limitations from a technical as well as a scientific point of view are addressed, allowing the reader not only to recognize the potential of a particular method for his/her own quest, but also to assess the resources that are required for implementation. The book is intended for use by graduate students and researchers in photosynthesis as well as in (bio)physics, (bio)chemistry and biology in general.
Analytical Techniques in the Oil and Gas Industry for Environmental Monitoring
The book discusses the conventional analyses for oil and natural gas feeds, along with their limitations. It offers detailed descriptions of advanced analytical techniques that are commercially available, plus explanations of gas and oil industry equipment and instrumentation. You’ll find technique descriptions supplemented with a list of references as well as with real-life application examples. With this book as a reference, you can prepare to apply specific analytical methods in your organization’s lab environment. Analytical Techniques can also serve as your comprehensive resource on key techniques in the characterization of oil and gas samples, within both refinery and environmental contexts.
Mathematical Approaches to Software Quality
This book considers the potential and limitations of the various mathematical approaches and thereby aims to give a balanced view of the usability of each mathematical approach. Written with both student and professional in mind, this book assists the reader in applying mathematical methods to solve practical problems that are relevant to software engineers. It is suitable for coursework or self-study and there is helpful material on tools to support the various mathematical approaches.
Many-Core Computing : Hardware and software
Provides a timely and coherent account of the recent advances in many-core computing research. Starting with programming models, operating systems and their applications; it presents runtime management techniques, followed by system modelling, verification and testing methods, and architectures and systems. Computing has moved away from a focus on performance-centric serial computation, instead towards energy-efficient parallel computation. This provides continued performance increases without increasing clock frequencies, and overcomes the thermal and power limitations of the dark-silicon era. As the number of parallel cores increases, we transition into the many-core computing era. There is considerable interest in developing methods, tools, architectures and applications to support many-core computing.
Citation Analysis in Research Evaluation
This book is written for members of the scholarly research community, and for persons involved in research evaluation and research policy. More specifically, it is directed towards the following four main groups of readers: – All scientists and scholars who have been or will be subjected to a quantitative assessment of research performance using citation analysis. – Research policy makers and managers who wish to become conversant with the basic features of citation analysis, and about its potentialities and limitations. – Members of peer review committees and other evaluators, who consider the use of citation analysis as a tool in their assessments. – Practitioners and students in the field of quantitative science and technology studies, informetrics, and library and information science. Citation analysis involves the construction and application of a series of indicators of the ‘impact’, ‘influence’ or ‘quality’ of scholarly work, derived from citation data, i.e. data on references cited in footnotes or bibliographies of scholarly research publications. Such indicators are applied both in the study of scholarly communication and in the assessment of research performance. The term ‘scholarly’ comprises all domains of science and scholarship, including not only those fields that are normally denoted as science – the natural and life sciences, mathematical and technical sciences – but also social sciences and humanities.
Anti-Spam Measures : Analysis and Design
The goal of this book is the methodical analysis of the potential, limitations, advantages, and drawbacks of anti-spam measures. These determine to which extent the measures can contribute to the reduction of spam in the long run. The range of considered anti-spam measures includes legislative, organizational, behavioral and technological ones. Furthermore, the conceptual development and analysis of an infrastructural email framework that features such a complementary application, is pointed out. The technological and organizational facets, the framework is analyzed twofold: its theoretical effectiveness is assessed with the aid of the formal model mentioned above, its storage and traffic requirements are analyzed quantitatively.
AI and IoT for smart city applications
Provides a valuable combination of relevant research works on developing smart city ecosystem from the artificial intelligence (AI) and Internet of things (IoT) perspective. The technical research works presented here are focused on a number of aspects of smart cities: smart mobility, smart living, smart environment, smart citizens, smart government, and smart waste management systems as well as related technologies and concepts. This edited book offers critical insight to the key underlying research themes within smart cities, highlighting the limitations of current developments and potential future directions.
Clinical Maxillary Sinus Elevation Surgery
Dr. Kao and a team of experts begin by discussing anatomy, radiographic image applications and limitations, and then provide step-by-step clinical procedures for the lateral window technique, including piezosurgery, and the trans-alveolar methods, including balloon and controlled hydostatic sinus elevation. Also included are chapters on post-operative care and complication management.
Clinical Guide to Accelerated Orthodontics : Wth a Focus on Micro-Osteoperforations
A complete reference for all clinicians who are interested in incorporating into their daily practice the techniques available to reduce the duration of orthodontic treatment and to overcome other treatment limitations. It focuses especially on micro-osteoperforations (MOPs) as the most conservative, efficient, and versatile approach to increase the rate of tooth movement.
Clinical applications of digital dental technology
Provides comprehensive yet practical references to a wide range of potential uses for digital technology in dental practice, discussing a wide range of digital technologies including their indications, contraindications, advantages, disadvantages, limitations, and applications. Overall, the book emphasizes how to use digital dentistry in daily practice across all specialties. With broad coverage of the subject, Clinical Applications of Digital Dental Technology discusses digital imaging, digital impressions, digital prosthodontics, digital implant planning and placement, and digital applications in endodontics, orthodontics, and oral surgery. Each chapter is written by experts in each topic and covers applications for prosthodontics, implant dentistry, oral surgery, endodontics, orthodontics, and other specialty areas.
3D imaging in endodontics : A new era in diagnosis and treatment
Full understanding of the role of cone beam computed tomography (CBCT) in helping to solve many of the most challenging problems in endodontics. It will shorten the learning curve in application of this exciting imaging technology in a variety of contexts: difficult diagnostic cases, treatment planning, evaluation of internal tooth anatomy prior to root canal therapy, nonsurgical and surgical treatments, early detection and treatment of resorptive defects, and outcomes assessment. The ability to obtain an accurate 3D representation of a tooth and the surrounding structures by means of noninvasive CBCT imaging is changing the approach to clinical decision making in endodontics. Clinicians long accustomed to working in very small, three-dimensional spaces are no longer constrained by the limitations of two-dimensional imaging. The challenges of mastering the new technology can, however, be daunting. The detailed guidance contained in this book will help endodontists to take full advantage of the important benefits offered by CBCT.
Basic Fracture Mechanics and its Applications
Presents specific aspects of how fracture mechanics is used to address fatigue crack growth, environment assisted cracking, and creep and creep-fatigue crack growth. Other topics include mixed-mode fracture and materials testing and selection for damage tolerant design, alongside in-depth discussions of ensuring structural integrity of components through real-world examples. There is a strong focus throughout the book on the practical applications of fracture mechanics. It provides a clear description of the theoretical aspects of fracture mechanics and also its limitations.
Asian economy and finance : A post-crisis perspective
Topicality of Asian economy has refused to fade for almost four decades; if anything it has been levitating. The Asian economy has changed markedly since the economic and financial crisis of 1997-1998 and is continuing to evolve. As a scholarly subject matter, Asian economy has not stopped attracting academicians, policy mandarins, decision makers in the arena of business and students of Asian economy. The Asian crisis was a cataclysmic event for the region and brought to the surface several systemic limitations, like those in the financial sector, corporate governance, regulatory oversight, legal framework, and exchange rate management. Managers of Asian economy need to get to the bottom of these acutely problematical systemic issues. Additionally, Asian economies need to change with the demands of time and devise their post-crisis development strategy. Asia’s growth model, that served it so well for four decades, is overdue for renewal so that it can re-strengthen its bonds with the ever-evolving regional and global economic reality. The old growth model is likely to be less relevant and effective in the post-crisis future of the Asian economies. It is sure to run into the wall of diminishing returns.
Aesthetics in digital photography
Aesthetics in Digital Photography presents theories developed over the last 25 centuries by philosophers and art critics, who have sometimes been governed by the objectivity of perception, and other times, of course, by the subjectivity of human judgement. It explores the advances that have been made in neuro-aesthetics and their current limitations.
A beginner's guide to urban design and development : the ABC of quality, sustainable design
Provides invaluable guidance to all those with an interest in placemaking and the built environment, from those with no experience to those who have worked for many years in industry, illustrating key principles that will secure higher quality, more sustainable design in accessible, jargon-free language. Explains the design process in a straightforward way, exploring the different roles and highlighting the opportunities and limitations different agencies have to influence design over the various stages of the process. Examples from the UK and worldwide look at how the system operates and how best practice can make a real difference on the ground. Case studies examine situations where quality or sustainability fell short – and how this could have been avoided. This book also showcases a variety of evaluation tools, explaining how they operate, and giving guidance on how to create project-specific tools to drive schemes forward. With community empowerment at its core, the book explains technical language and shares bountiful knowledge to broaden place democracy and make influencing design accessible to many, not just a few.
Linear Optimization Problems with Inexact Data
Linear programming attracted the interest of mathematicians during and after World War II when the first computers were constructed and methods for solving large linear programming problems were sought in connection with specific practical problems—for example, providing logistical support for the U.S. Armed Forces or modeling national economies. Early attempts to apply linear programming methods to solve practical problems failed to satisfy expectations. There were various reasons for the failure. One of them, which is the central topic of this book, was the inexactness of the data used to create the models. This phenomenon, inherent in most pratical problems, has been dealt with in several ways. At first, linear programming models used "average” values of inherently vague coefficients, but the optimal solutions of these models were not always optimal for the original problem itself. Later researchers developed the stochastic linear programming approach, but this too has its limitations. Recently, interest has been given to linear programming problems with data given as intervals, convex sets and/or fuzzy sets. The individual results of these studies have been promising, but the literature has not presented a unified theory. Linear Optimization Problems with Inexact Data attempts to present a comprehensive treatment of linear optimization with inexact data, summarizing existing results and presenting new ones within a unifying framework.
