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Cardiac Mechanotransduction
For about hundred years the investigation of heart physiology has had one central guiding principle, the "law" of Frank and Starling. This connects the return of blood into the heart and the blood pressure with cardiac con traction force. The "law" does it in a way that enables the cardiovascular system to react to perturbations without major malfunctions. This book is a compilation of reviews of prominent scientists on this subject. The differ ence of the original formulation of the Frank-Starling principle is that mechanotransduction is the central theme that leads the reader through the book. Since the discovery of the "law" the scope of topics related to this subject has broadened enormously, as can be seen easily by glancing at the contents of this book. Mechanotransduction in the heart has many faces that range from molecules to humans and their diseases.
Basis and Treatment of Cardiac Arrhythmias
Incorporating the information related to mechanisms and treatment of cardiac arrhythmia, this book discusses genetics of arrhythmias, cell signalling molecules as potential therapeutic targets and trafficking to the membrane. These approaches and implementations of anti-arrhythmic therapy derive from many decades of research.
Autonomous control for a reliable internet of services : Methods, models, approaches, techniques, algorithms, and tools
This open access book was prepared as a Final Publication of the COST Action IC1304 “Autonomous Control for a Reliable Internet of Services (ACROSS)”. The book contains 14 chapters and constitutes a show-case of the main outcome of the Action in line with its scientific goals. It will serve as a valuable reference for undergraduate and post-graduate students, educators, faculty members, researchers, engineers, and research strategists working in this field. The objective of this book is, by applying a systematic approach, to assess the state-of-the-art and consolidate the main research results achieved in this area.
Leveraging Mobile Media : Cross-Media Strategy and Innovation Policy for Mobile Media Communication
Mobile communications and next generation wireless networks emerge as new distribution channels for the media. This development offers exciting new opportunities for media companies: the mobile communication system creates new usage contexts for media content and services; the social use of mobile communications suggests that identity representation in social networks, impulsive access to trusted media brands, and micro-coordination emerge as new sources of value creation in the media industries. In the light of this background, this book takes two different viewpoints on the development of mobile media: from a competitive strategy point of view it analyzes the extension of cross-media strategies and the emergence of cross-network strategies; from a public policy point of view it develops demands and requirements for an innovation policy that fosters innovation in mobile media markets.
Agile Marketing Performance Management : 10 Success Factors for Maximizing Marketing ROI Dynamically
Helps marketing decision makers in allocating their budget to diverse communication channels and different business units in an ROI-optimal way, and to adapt it in an agile manner.
Biological Membrane Ion Channels : Dynamics, Structure, and Applications
Ion channels are biological nanotubes that are formed by membrane proteins. Because ion channels regulate all electrical activities in living cells, understanding their mechanisms at a molecular level is a fundamental problem in biology. This book deals with recent breakthroughs in ion-channel research that have been brought about by the combined effort of experimental biophysicists and computational physicists, who together are beginning to unravel the story of these exquisitely designed biomolecules. With chapters by leading experts.
