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Making Healthcare Safe : The Story of the Patient Safety Movement

This unique and engaging open access title provides a compelling and ground-breaking account of the patient safety movement in the United States, told from the perspective of one of its most prominent leaders, and arguably the movement’s founder, Lucian L. Leape, MD. Covering the growth of the field from the late 1980s to 2015, Dr. Leape details the developments, actors, organizations, research, and policy-making activities that marked the evolution and major advances of patient safety in this time span. In addition, and perhaps most importantly, this book not only comprehensively details how and why human and systems errors too often occur in the process of providing health care, it also promotes an in-depth understanding of the principles and practices of patient safety, including how they were influenced by today’s modern safety sciences and systems theory and design. Indeed, the book emphasizes how the growing awareness of systems-design thinking and the self-education and commitment to improving patient safety, by not only Dr. Leape but a wide range of other clinicians and health executives from both the private and public sectors, all converged to drive forward the patient safety movement in the US.

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Lactic acid bacteria : Methods and protocols

This updated volume presents experimentation-based approaches to lactic acid bacteria (LAB) research. Split into three parts, the book explores techniques for analyzing lactic acid bacteria metabolism and characteristics, applications for food-related industries, such as yogurt production, beer, and wine making, and functions of LAB in human health. Written for the highly successful Methods in Molecular Biology series, chapters include introduction to their respective topic, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

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Chitosan : properties and applications in bioengineering

Presents a review of chitosan, including information regarding its structure, main properties, available sources, extraction, and processing techniques. It presents the different applications of chitosan as a biomaterial in fields such as medicine and the agricultural, cosmetology, pharmaceutical, and food industries to have readers obtain a more technical vision of the current use of this biopolymer.

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Chemical principles of nanoengineering

Nanomaterials, which possess at least one dimension lower than 100 nanometers, are increasingly at the forefront of technological and chemical innovation. The properties of these uniquely minute materials give them distinctive applications across a huge range of industries and research fields. It is therefore critical that the next generation of engineers and materials scientists understand these materials, their chemical properties, and how they form bonds

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Checkpoint Responses in Cancer Therapy

This book’s distinguished panel of authors takes a close look at topics ranging from the major molecular players affecting DNA synthesis and the response to DNA damage to advances made in the identification of chemical compounds capable of inhibiting individual mitotic kinases. Illuminating and authoritative, Checkpoint Responses in Cancer Therapy offers a critical summary of findings for researchers in the pharmaceutical and biotechnology industries and a valuable resource for academic scientists in cancer research and the study of cell-cycle regulation, signal transduction and apoptosis.

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CADD and informatics in drug discovery

Updates knowledge on recent advances in computational and bioinformatics tools/techniques and their practical applications in modern drug design and discovery programme. Also it encompasses fundamental principles, advanced methodologies and applications of various CADD approaches including several cutting-edge areas / presenting recent developments covering ongoing trends in the field of computer-aided drug discovery. Having contributions by a global team of experts, the book is expected to be an ideal resource for drug discovery scientists, medicinal chemists, pharmacologists, toxicologists, phytochemists, biochemists, biologists, RandD personnel, researchers, students, teachers and those working in the field of drug discovery. It will fill the knowledge gaps that exist in the current CADD approaches and methodologies/ protocols being widely used in both academic and research practices. Further, a special focus on current status of various computational drug design approaches (SBDD, LBDD, De-novo drug design, Pharmacophore-based search), bioinformatics tools and databases, computational screening and modeling of phytochemicals/natural products, artificial intelligence and machine learning, and network pharmacology and system biology would certainly guide researchers, students or readers to conduct their research in the emerging area(s) of interest. It is also expected to be highly beneficial to different stakeholders working in the pharmaceutical and biotechnology industries (RandD), the academic as well as research sectors. .

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Bioprocessing Technology for Production of Biopharmaceuticals and Bioproducts

Written for industrial and academic researchers and development scientists in the life sciences industry, Bioprocessing Technology for Production of Biopharmaceuticals and Bioproducts is a guide to the tools, approaches, and useful developments in bioprocessing. This important guide: •Summarizes state-of-the-art bioprocessing methods and reviews applications in life science industries •Includes illustrative case studies that review six milestone bio-products •Discuses a wide selection of host strain types and disruptive bioprocess technologies

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Biomaterials and bionanotechnology ; 1st ed.

Examines the current state of the field within pharmaceutical sciences and concisely explains the history of biomaterials including key developments. Written by experts in the field, this volume within the Advances in Pharmaceutical Product Development and Research series deepens understanding of biomaterials and bionanotechnology within drug discovery and drug development. Each chapter delves into a particular aspect of this fast-moving field to cover the fundamental principles, advanced methodologies and technologies employed by pharmaceutical scientists, researchers and pharmaceutical industries to transform a drug candidate or new chemical entity into a final administrable dosage form, with particular focus on biomaterials and bionanomaterials. This book provides a comprehensive examination suitable for researchers working in the pharmaceutical, cosmetics, biotechnology, food and related industries as well as advanced students in these fields.

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Bioactive egg compounds

Hen eggs have exceptional potential as an inexhaustible source for a variety of products with unique properties. These products are valuable to human health and nutrition and can be used as raw materials for diverse purposes in the cosmetics and pharmaceutical industries. Bioactive Egg Compounds presents the latest results and concepts in the biotechnological use of egg compounds. Following an introduction to the different compounds of egg white, yolk and shell, the nutritive value of egg compounds is discussed. Procedures for processing egg compounds to improve their nutritive value are described, including the concept of so-called enriched eggs. Also described is the isolation and application of egg compounds with special properties, such as antibiotic action.

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Bee products and their applications in the food and pharmaceutical industries ; 1st ed.

Focuses on the health benefits of selected bee products by looking more closely at their pharmacological potentials and therapeutic applications in coping with various diseases. The book explores some of these products, such as royal jelly, propolis and bee venom, which is highly attractive to the food supplement sector due to the biological actions that are proved by scientific studies. Bee products also attract the cosmetics industry by utilizing those products in various applications such as hair products, toothpaste, sunscreen creams, lip balsams, or facial moisturizing creams. Each chapter focuses on a particular health benefit, providing more compact and detailed information about each activity for a specific interest. The mainframe of the book is based on the medicinal and pharmacological functions of bee products, with the therapeutic applications for each bee product supporting the mechanism of action of their biological functions.

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Application of microbes in environmental and microbial biotechnology

Discusses the innovative approaches and investigation strategies, as well as provides a broad spectrum of the cutting-edge research on the processing, properties and technological developments of microbial products and their applications. Microbes finds very important applications in our lives including industries and food processing. They are widely used in the fermentation of beverages, processing of dairy products, production of pharmaceuticals, chemicals, enzymes, proteins and biomaterials / conversion of biomass into fuel, fuel cell technology, health and environmental sectors. Some of these products are produced commercially, while others are potentially valuable in biotechnology. Microorganisms are considered invaluable in research as model organisms. This is a useful compilation for students and researchers in microbiology, biotechnology and chemical industries.

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Blockchain, artificial intelligence, and the internet of things : Possibilities and opportunities

Provides basic concepts and deep knowledge about various security mechanisms that can be implemented in IoT through Blockchain technology. This book aids readers in gaining insight and knowledge about providing security and solutions to different challenges in IoT using Blockchain technology. This book primarily focuses on challenges to addressing the integration of the IoT with Blockchain with respect to potential benefits for IoT. This book gives descriptive analysis of Blockchain integrated with IoT applications and platforms for the development of IoT solutions along with possible topologies to that integration. Several application examples are included in a variety of industries / Provides the latest on secure IIoT communication using Blockchain technology for Industry 4.0 / Includes updates on using Blockchain technology in secure vehicular communication (VANET), healthcare, retail, and gaming / Provides the latest on secure IIoT communication using Blockchain technology for Industry 4.0

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Machine-learning-assisted intelligent processing and optimization of complex systems

Focuses on the most recent developments in intelligent optimization methods and their applications in various test cases. The reprint covers various topics, including distributed multiagent modeling, metaheuristic algorithms, multisource data fusion, mobile computing and mobile sensing, machine learning-based intelligent processing for modeling complex manufacturing systems, and data-driven intelligent modeling

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Advanced Nanomaterials

Covers synthesis, characterization, and applications of diverse types of nanomaterials. Specifically, it describes carbon, graphene, and graphene oxide-based nanomaterials and their use for environmental remediation. Nanomaterials for concrete coating applications and advances in the processing of high-entropy alloys by means of mechanical alloying are also covered. Subsequently, the use of nanomaterials in endodontics and the use of nanotechnology strategies to enhance restorative resin-based dental nanomaterials are reported.

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Building services engineering for construction T level: core

Provides complete coverage of the Building Services Engineering for Construction qualification's core units and will equip you with the skills you need to shape your career. - Break down complex topics with summary tables and hundreds of images and artworks - Apply your knowledge in real-world case studies and discover some of the dilemmas you can.

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Marketing the Arts : Breaking Boundaries

The importance of arts consumption and its socio-cultural, political, and economic dimensions The impact of new technologies, platforms, and alternative artforms on the art market The importance of the aesthetic experience itself and how to research it The value of arts-based methods The art versus commerce debate The artist as entrepreneur The role of the arts marketer as market-maker

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Managing innovation in organisations : ostering an entrepreneurial approach

Explores how organisations need to manage their innovation processes in order to compete in the global marketplace. Innovation is essential to the ongoing competitiveness of organisations but can be difficult to capture and disseminate. This book states that there needs to be guidelines about how to manage innovation in an organisational context. This includes focusing on different types of innovation from incremental to radical. This book will focus on ways to manage innovation from incorporating it into organisational practices to implementing it into beneficial partnerships.

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Management of Regulatory Influences on Corporate Strategy and Structure

In many industries, e.g. telecommunications, transportation, energy, chemicals, food and beverages, firm performance is heavily influenced by regulation. Despite this fact, strategic management research has traditionally focused on market strategies and related issues. Questions of how to manage regulatory involvement have been left to separate research streams on corporate political activity and a broader understanding of the complex inter-dependencies and mutual influences between corporate and external actors remains lacking.

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Management of Innovation in Network Industries : The Mobile Internet in Japan and Europe

This book focuses on the following questions: Which are the implications of different approaches towards management of systemic innovations? Do differences matter and why do they matter? The author shows that Europeans can learn from the Japanese and gives advice for future approaches to developments in the European telecommunications industry.

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Management of Convergence in Innovation : Strategies and Capabilities for Value Creation Beyond Blurring Industry Boundaries

Throughout the past decade, the phenomenon of technological convergence has increasingly gained managerial attention. In this special form of technological change, the coming-together of previously distinct knowledge bases gives rise to the creation of new applications and business models. When such innovations emerge at the intersection of industries, the resulting creative destruction may exceed previously established industry boundaries. As a consequence, convergence does not only promise the creation of new value, but may imply significant disruptions to established industries. Based on investigating 26 firms within the ICT industry, this book highlights implications of the convergence phenomenon on firms’ innovation management practices, and derives strategic guidelines for building and sustaining business models beyond blurring industry boundaries.

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