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Biologie und epidemiologie der hormonersatztherapie : Diskussionen zur postmenopausalen gesundheit = Biology and epidemiology of hormone replacement therapy : Discussions on postmenopausal health
The advantages and disadvantages of hormone replacement therapy (HRT) are discussed by a group of experts with regard to the epidemiological evidence. However, the focus of the discussion is the problem of breast cancer risk. Among other things, it is shown that the results derived from epidemiological studies do not coincide with the growth characteristics of these tumors, so that further population studies with the inclusion of pathobiological expertise appear necessary. The benefits and risks of hormone replacement therapy (HRT) are discussed by a group of experts with a view towards the evidence provided by recent epidemiological studies. Although all aspects of HRT indications and contra-indications are reviewed, the particular emphasis of this discussion is on breast cancer. Among other things, it is shown that the evidence on breast cancer provided in epidemiological studies does not match the growth characteristics of the tumors, and that further population research incorporating pathobiological assessments is required.
Alzheimer : 100 Years and Beyond
Few medical or scientific addresses have so unmistakeably made history as the presentation delivered by Alois Alzheimer on November 4th, 1906 in Tübingen. The celebratory event, "Alzheimer 100 Years and Beyond" organized on the initiative of the Alzheimer community in Germany and worldwide, in collaboration with the Fondation Ipsen, at the very site of the original lecture, namely the Institute of Psychiatry at the University of Tübingen in Germany from November 2nd to 5th, 2006, was the highlight of the Alzheimer Year. Over the last century of Alzheimer research (1906-2006), remarkable progress has been achieved. Most of the authors of the major discoveries and the people involved in research in this field will present, during the meeting and in this volume, the pioneering research explaining the conditions under which they were conducted. The goal of this book is to honor the work accomplished, to summarize the most important knowledge and to provide material for the history of science.
Aging Well : Solutions to the Most Pressing Global Challenges of Aging
Outlines the challenges of supporting the health and wellbeing of older adults around the world and offers examples of solutions designed by stakeholders, healthcare providers, and public, private and nonprofit organizations in the United States. The solutions presented address challenges including: providing person-centered long-term care, making palliative care accessible in all healthcare settings and the home, enabling aging-in-place, financing long-term care, improving care coordination and access to care, delivering hospital-level and emergency care in the home and retirement community settings, merging health and social care, supporting people living with dementia and their caregivers, creating communities and employment opportunities that are accessible and welcoming to those of all ages and abilities, and combating the stigma of aging. The innovative programs of support and care in Aging Well serve as models of excellence that, when put into action, move health spending toward a sustainable path and greatly contribute to the well-being of older adults.
Logic for Computer Scientists
This book introduces the notions and methods of formal logic from a computer science standpoint, covering propositional logic, predicate logic, and foundations of logic programming. It presents applications and themes of computer science research such as resolution, automated deduction, and logic programming in a rigorous but readable way.The style and scope of the work, rounded out by the inclusion of exercises, make this an excellent textbook for an advanced undergraduate course in logic for computer scientists.
Liapunov Functions and Stability in Control Theory
Presents a modern and self-contained treatment of the Liapunov method for stability analysis, in the framework of mathematical nonlinear control theory. A Particular focus is on the problem of the existence of Liapunov functions (converse Liapunov theorems) and their regularity, whose interest is especially motivated by applications to automatic control.
Algorithms in Bioinformatics : Theory and Implementation
Explores a comprehensive and insightful treatment of the practical application of bioinformatic algorithms in a variety of fields. Delivers a fulsome treatment of some of the main algorithms used to explain biological functions and relationships. It introduces readers to the art of algorithms in a practical manner which is linked with biological theory and interpretation. The book covers many key areas of bioinformatics, including global and local sequence alignment, forced alignment, detection of motifs, Sequence logos, Markov chains or information entropy. Other novel approaches are also described, such as Self-Sequence alignment, Objective Digital Stains (ODSs) or Spectral Forecast and the Discrete Probability Detector (DPD) algorithm. Readers will also benefit from the inclusion of: A detailed presentation of new methods, such as Self-sequence alignment, Objective Digital Stains and Spectral Forecast ; A treatment of sequence alignment, including local sequence alignment, global sequence alignment and forced sequence alignment with full implementations ; Discussions of position-specific weight matrices, including the count, weight, relative frequencies, and log-likelihoods matrices ; A detailed presentation of the methods related to Markov Chains as well as a description of their implementation in Bioinformatics and adjacent fields ; An examination of information and entropy, including sequence logos and explanations related to their meaning ; A chapter on philosophical transactions that allows the reader a broader view of the prediction process ; Extensive worked examples with detailed case studies that point out the meaning of different results
Marketing ; 16th ed.
Expanded coverage on social responsibility and sustainability topics such as privacy, social entrepreneurship, diversity, equity, inclusion, and environmental impact. The 16e continues its real-world focus with “Marketing Matters,” “Making Responsible Decisions,” “Insights about me,” “Applying Marketing Metrics,” “Integration of the Customer Journey” and “Building your Marketing Plan” features throughout. Key marketplace changes related to the pandemic such as curbside pick-up, touchless payment, and delivery have been incorporated.
Making sense of work through collaborative storytelling : Building narratives in organisational change
This book focuses on the development of collaborative practices at work, and in organisations, through stories: from sharing stories to exchanging experiences and building a common narrative collectively.
Banking on (artificial) intelligence : Navigating the realities of ai in financial services
Provides a tailored overview of what AI specifically means for financial services, a highly regulated yet also disrupted industry. it investigates the current state of AI applications in financial services today along with the state of funding and partnerships between tech and banking industries. it also examines the key pillars of responsible AI and the importance of keeping humans in the loop. the book takes a deep dive into the use cases in the financial services industry, the challenges and opportunities, and the fragmented regulatory landscape. how can we effectively assess risks, and balance innovation and customer centricity with trust in AI in financial services? can smaller organizations reap the benefits of the technology? how can institutions deploy AI responsibly and securely, and promote a fairer and more equitable future for more people?
Community schools : Designing for sustainability, wellbeing and inclusion
Reconsiders what is required from physical school environments, building on the learning gathered from the sector over the past two decades. To meet the new social, environmental and economic challenges it advocates designing differently, both in terms of the form that buildings take and the evaluation of their impact and performance. By calling for a reframing of the way that schools are regarded as community-wide amenities, this book explores the potential for architects to deliver design in a manner that supports healthy lifestyles and promotes wellbeing. Through encouraging social connections, new possibilities open up for educational facilities to become open, welcoming and inclusive. Featuring: Over 12 international case studies from practices including: Architype, Argyll + Bute, Bogle Architects, DRMM, Revaerk, Scott Brownrigg and XDGA. Key themes of wellbeing, connectivity, inclusion, indicators and evaluation. Practical guidance and learning points throughout. A new design brief for community schools
Lifelong Learning, Participation and Equity
In many countries, schools, universities and other traditional learning institutions are not providing for the educational needs of all members of the community. In many communities, particularly in regional, rural and disadvantaged areas, there are only limited options for people to undertake learning. Limited participation in learning has the danger of reinforcing people’s alienation from mainstream education and from participation and inclusion in social institutions and economic and community life more generally. This book addresses the challenge of identifying effective ways of accommodating the learning needs of all people and in so doing achieving the goals of lifelong learning for all.
Children's Exploration and Cultural Formation
This book examines the educational conditions that support cultures of exploration in kindergartens. It conceptualises cultures of exploration, whether those cultures are created through children’s own engagement or are demanded of them through undertaking specific tasks within different institutional settings.
Advanced Magnetic Nanostructures
Advanced Magnetic Nanostructures is devoted to the fabrication, characterization, experimental investigation, theoretical understanding, and utilization of advanced magnetic nanostructures. Focus is on various types of 'bottom-up' and 'top-down' artificial nanostructures, as contrasted to naturally occurring magnetic nanostructures, such as iron-oxide inclusions in magnetic rocks, and to structures such as perfect thin films. Industrial and academic researchers in magnetism and related areas such as nanotechnology, materials science, and theoretical solid-state physics will find this book a valuable resource.
