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Monographs in contact allergy ; Vol.4 : Systemic drugs

Presents : Identification section; Occupational allergic contact dermatitis; and Cutaneous adverse drug reactions from systemic drugs caused by type IV (delayed-type) hypersensitivity, as shown by positive patch tests (e.g. maculopapular eruption, acute generalized exanthematous pustulosis [AGEP], symmetrical drug-related intertriginous and flexural exanthema [SDRIFE], fixed drug eruption, drug reaction with eosinophilia and systemic symptoms [DRESS], and photosensitivity). Separate chapters present an overview of the spectrum of allergic cutaneous drug reactions, diagnostic tests, immediate contact reactions (contact urticaria), and systemic drugs that have acquired delayed-type hypersensitivity only by cross-reactivity.

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Innovative Endocrinology of Cancer

Deals with developments in such topics as mechanisms of hormonal carcinogenesis, epidemiology and risk factors, hormone production by tumor tissue and hormonal sensitivity of the latter, genesis, dichotomy and endocrinology of cancer in females, and pharmacogenomics and proteomics in oncoendocrinology.

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Hypersensitivity = فرط الحساسية

فرط التحسس هو عبارة عن ردود فعل لجهاز المناعة تسبب ظواهر غير مرغوب بها تشمل تضرر الأنسجة و الإمراض المتعددة هذه الظواهر المرضية الناجمة عن نشاط جهاز المناعة تسمى ظواهر فرط التحسس حيث إن جهاز المناعة يحمي الجسم من الأجسام الضارة الخارجية وخاصة الملوثات و السبب الأكثر شيوعا لحدوث ظواهر فرط التحسس هي عدم تمييز جهاز المناعة أحيانا بين الأجسام الذاتية وبين الأجسام الدخيلة هذا التمييز يشكل صفه ضرورية لجهاز المناعة لضمان أداء وضيفي سليم وحتى ليقوم جهاز المناعة بمهاجمة الأنسجة الذاتية أمراض فرط التحسس من الممكن ان تحدث بسبب رد فعل مناعي مفرط ضد مسببات خارجية مثلما هو الحال مع إمراض الحساسية .

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Food allergies processing technologies for allergenicity reduction

Provides an authoritative source of information on the relationship between food processing technologies and food allergens with a greater variety of studied allergens including peanuts, tree nuts, cow’s milk, eggs, sesame, lupine, soy, wheat, mustard, mushroom, fish and shellfish, as well as the importance of processing these when producing hypoallergenic foods.

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Food allergens : methods and protocols

Provides a comprehensive collection of methods and protocols in food allergy and food allergens studies. The selected protocols explore the study of food allergens, from recombinant production, purification procedures, IgE and T cell epitopes characterization, to allergen structure description, cellular responses, and tolerance induction, through a variety of techniques and animal models.

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Essential Quick Review : Operative Dentistry & Endodontics

Provides a complete outline for writing an essay type, a short answer type, or a viva voce type of questions. Written in a simple language along with well-illustrated diagrams wherever possible. Supported with a supplementary booklet for each subject containing three sections: definitions, classifications, and viva voce.

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Dentine Hypersensitivity: Advances in Diagnosis, Management, and Treatment

Provides wide-ranging information on the progress achieved in the diagnosis, treatment and management of dentine hypersensitivity during the past few years. Recent advances in research, including innovations in the development of desensitizing agents, are fully described and detailed attention is paid to novel clinical approaches and potential future strategies in product development.

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Dental erosion and its clinical management

In this handbook, the most up-to-date theoretical and practical information on dental erosion is distilled into an accessible, practical, and clinically focused format. Topics are covered in a step-by-step, easy-to-understand manner, with tables, checklists, images, flowcharts, and bullet point-like presentation of core messages that is ideal for busy dental practitioners and students. Procedures and products not yet supported with evidence are not included. Besides providing evidence-based guidance on the varied treatment and prevention strategies, the book examines thoroughly the dental erosion process itself and the intrinsic and extrinsic causes. In addition, careful attention is paid to the etiology, prevalence, and management of dentin hypersensitivity, the restoration of worn dentin, and non-carious cervical lesions. Provides step-by-step, evidence-based guidance on clinical management procedures for dental erosion / Describes the etiology, prevalence, and treatment of dentin hypersensitivity / Discusses restoration of worn dentin and non-carious cervical lesions / Includes informative color images, tables, summary boxes, and flowcharts

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Cough : Pathophysiology, diagnosis and treatment

This book provides an updated and comprehensive overview of cough, while opening new perspectives for their treatment and management. It enables readers to not only discover new physiologic features and mechanisms but also to gain an in-depth understanding of the diagnostic workup of cough, still one of the most frequent and challenging symptoms in daily medical practice. The book also provides insights into cough’s features and pathogenesis, as well as into pharmacologic and non-pharmacologic treatments. The most frequent causes of chronic cough (asthma, postnasal drip, gastroesophageal reflux and chronic hypersensitivity syndrome) and different types of pediatric cough are also explored.

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Clinician's guide to the diagnosis and management of tooth sensitivity

Tooth sensitivity, or dentin hypersensitivity, has a high prevalence among the general population and is a very common cause of visits to the dentist. This guide provides the clinician with the most important information required for the correct diagnosis and effective management of dentin hypersensitivity.

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Les douleurs abdominales en questions : Rôle physiopathologique de la sensibilité viscérale = Abdominal pain in question : The pathophysiological role of visceral sensitivity

The gut-brain axis refers to the network of nerve pathways that connect the myenteric plexus, the veritable "gut brain," to the central nervous system. Nearly 80% of these neurons are sensory neurons, and the afferent pathways that transmit information from the digestive tract to the central nervous system play a crucial role in the physiological regulation of digestive functions, as well as in certain pathological conditions. A large majority of these sensations remain unconscious and give rise to reflex responses. Only those requiring a conscious response reach the level of awareness in a normal state (hunger, thirst, the urge to defecate). In pathological situations, the same is true for painful sensations of digestive origin. Functional bowel disorders are a frequent reason for consultation. Their pathophysiology is now based on a model integrating the various etiological factors around the brain-gut axis. These patients frequently present with visceral hypersensitivity, which manifests as an increased perception of digestive sensations, notably the onset of pain in response to stimuli that are not painful in normal subjects. Recognizing the role of visceral hypersensitivity has made it possible to explain the mechanism of action of medications used to treat functional bowel disorders and paves the way for the development of new molecules acting on digestive afferents. In this book, we will describe the anatomical and physiological basis for understanding the concept of visceral sensitivity and the role of digestive afferents in the pathophysiology of acute and chronic abdominal pain, particularly irritable bowel syndrome.

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Basic immunology : Functions and disorders of the immune system

Includes recent important advances in our understanding and knowledge of the immune system. A student favorite through six outstanding editions, this new edition uses full-color illustrations and clinical images, useful tables, and practical features such as Summary Point boxes, end-of-chapter review questions, glossary terms, and clinical cases—all designed to help you master this complex topic in the most efficient, effective manner possible.

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Apitherapy and therapeutic properties

Apitherapy is an alternate therapy that relies on the usage of honeybee products, most importantly bee venom for the treatment of many human diseases. Bee venom contains several active molecules such as peptides and enzymes that have advantageous potential in treating inflammation and central nervous system diseases, such as Parkinson’s disease, and Alzheimer’s disease and autoimmume diseases like reumatic and atherosclerosis .Bee venom (BV) is usually associated with pain since, when humans are stung by bees,local inflammation and even an allergic reaction can be produced. It also consists of a mixture of proteins and peptides, including enzymes such as Melittin and phospholipase A2 (PLA2) are the most abundant and studied compounds of BV Stings of hymenoptera can induce IgE-mediated hypersensitivity reactions in venom-allergic patients, ranging from local up to severe systemic reactions and even fatal anaphylaxis. skin is larger than any other organ in humans.

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Adverse Food Reaction

Adverse food reaction is a broad term indicating a link between an ingestion of a food and an abnormal response. Adverse reactions to foods, aside from those considered toxic, are caused by a particular individual intolerance towards commonly tolerated foods. Intolerance derived from an immunological mechanism is referred to as Food Allergy, the non-immunological form is called Food Intolerance. IgE-mediated food allergy is the most common and dangerous type of adverse food reaction. It is initiated by an impairment of normal Oral Tolerance to food in predisposed individuals (atopic). Food allergy produces respiratory, gastrointestinal, cutaneous and cardiovascular symptoms but often generalized, life-threatening symptoms manifest at a rapid rate-anaphylactic shock.

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