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Open and Closed Innovation : Different Cultures for Different Strategies
Open Innovation is a phenomenon in both research and management practice. Since radical innovation or new business development often require external technologies or ways of commercialization, many firms have shifted from a Closed to an Open Innovation model. However, firms often face difficulties during the implementation. While the implementation effort usually focuses on external ideas and technologies as well as the processes to identify them, cultural challenges are neglected. Philipp Herzog develops a theoretical framework arguing that Open Innovation and Closed Innovation cultures need to be different (e.g. regarding the not-invented-here (NIH) syndrome). Based on a multi-respondent survey among 120 R&D employees from three business units of a leading chemical firm, he provides empirical evidence for many of the hypothesized differences in innovation culture.
Nuclear Energy : Principles, Practices, and Prospects
The world faces serious difficulties in obtaining the energy that will be needed in coming decades for a growing population, especially given the problem of climate change caused by fossil fuel use. This book presents a view of nuclear energy as an important carbon-free energy option. It discusses the nuclear fuel cycle, the types of reactors used today and proposed for the future, nuclear waste disposal, reactor accidents and reactor safety, nuclear weapon proliferation, and the cost of electric power. To provide background for these discussions, the book begins with chapters on the history of the development and use of nuclear energy, the health effects of ionizing radiation, and the basic physics principles of reactor operation. The text has been rewritten and substantially expanded for this edition, to reflect changes that have taken place in the eight years since the publication of the first edition and to provide greater coverage of key topics. These include the Yucca Mountain repository plans, designs for next-generation reactors, weapons proliferation and terrorism threats, the potential of alternatives to nuclear energy, and controversies about low-level radiation.
Nonlinear Integer Programming
It is not an exaggeration that much of what people devote in their hfe re solves around optimization in one way or another. On one hand, many decision making problems in real applications naturally result in optimization problems in a form of integer programming. On the other hand, integer programming has been one of the great challenges for the optimization research community for many years, due to its computational difficulties: Exponential growth in its computational complexity with respect to the problem dimension. This book addresses the topic of the general nonlinear integer programming (NLIP). The overall goal of the book is to bring the state of the art of the theoretical foundations and solution methods of NLIP to readers who are interested in optimization, operations research and computer science. This book investigates the theory and solution methodologies for the general NLIP and provides the developments
Neurology Oral Boards Review : A Concise and Systematic Approach to Clinical Practice
Rapid recall of vast amounts of factual material is the key to success in both the Neurology Oral Board examination and in everyday patient care. In Neurology Oral Boards Review: A Concise and Systematic Approach to Clinical Practice, Eroboghene E. Ubogu offers a comprehensive review of relevant topics and examination strategies needed to pass the American Board of Psychiatry and Neurology (ABPN) Part II (Oral) exam, complete with up-to-date, evidence-based guidelines on diagnosis and management in clinical neurology. The author has written the book specifically to satisfy the requirements of the ABPN, with clinical case vignettes designed to allow the examinee to localize the plausible disease process, to indicate which investigations may help in establishing a diagnosis, to deduce treatment plans, and to make a prognosis, including patient and family counseling. The emergency cases test the ability to think critically when faced with a neurological emergency, putting a premium on resuscitation, patient safety, and rapid high-yield investigations. The general neurology cases reflect the breadth of disorders experienced in hospital and outpatient settings. The author also provides a detailed description of the oral ABPN examination and suggests a study regimen that takes into account the difficulties of allotting time to prepare while in post-residency training or practice.
Natural Language Processing and Text Mining
Natural Language Processing and Text Mining not only discusses applications of certain NLP techniques to certain Text Mining tasks, but also the converse, i.e., use of Text Mining to facilitate NLP. It explores a variety of real-world applications of NLP and text-mining algorithms in comprehensive detail, placing emphasis on the description of end-to-end solutions to real problems, and detailing the associated difficulties that must be resolved before the algorithm can be applied and its full benefits realized.
Napoleonic Governance in the Netherlands and Northwest Germany : Conquest, Incorporation, and Integration
This Palgrave Pivot explores the ways in which French Emperor Napoleon tried to integrate the present-day Netherlands and Northwest Germany into his Empire, by replacing traditional institutions and governing practices with French ones ('Napoleonic governance'). The northern periphery of the Napoleonic Empire continues to be overlooked by the bulk of historians; this study shows that a transregional approach can yield important findings. In a broader sense, the study does not deal with these regions alone, but also with the difficulties that are inherent to European integration.
Mute people aiding application
Communication is an essential tool for human survival. It is a fundamental and effective method of sharing thoughts, needs, feelings, and opinions. However, a large portion of the world's population lacks the ability to communicate with others. Such as the ones suffering from hearing loss, speech disability, or even both. Those disabilities have a significant impact on their lives in terms of work and relationships. The majority of these people are sometimes unable to support themselves financially due to the lack of job opportunities. Given these difficulties, we have decided to develop an application to help them overcome the obstacles they may encounter in their daily lives. After consulting with two deaf and mute people we customized an application that works in two ways. One of which is to translate their sign language in real time by using mobile camera and recognizing hand motion. The other works by converting text-to-voice, and accurately expressing the user’s emotions with the help of the facial emotion recognition.
Multidimensional Screening
The book brings into a focus all necessary mathematical knowledge necessary to understand the economics of multidimensional results screening and applies them straightaway to economic models. The first part of this book contains a review of vector calculus, the theory of partial differential equations, and the theory of generalized convexity. These techniques are extensively used in multidimensional screening models. Part II is devoted to the economics of sceening models. It starts with a detailed discussion of economics and mathematics of unidimensional screening problems and three approaches to their solution: direct, dual, and Hamiltonian. It uses the Hamiltonian approach to unify all known results, which were previously obtained using different arguments. Then the major difficulties with direct and dual approach in the multidimensional context are discussed and the Hamiltonian approach is used to provide the most complete characterization of the solution known in the literature.
Molecular and Cellular Signaling
A small number of signaling pathways, no more than a dozen or so, form a control layer that is responsible for all signaling in and between cells of the human body. The signaling proteins belonging to the control layer determine what kinds of cells are made during development and how they function during adult life. Malfunctions in the proteins belonging to the control layer are responsible for a host of human diseases ranging from neurological disorders to cancers. Most drugs target components in the control layer, and difficulties in drug design are intimately related to the architecture of the control layer. Molecular and Cellular Signaling provides an introduction to molecular and cellular signaling in biological systems with an emphasis on the underlying physical principles. The text is aimed at upper-level undergraduates, graduate students and individuals in medicine and pharmacology interested in broadening their understanding of how cells regulate and coordinate their core activities and how diseases arise when these regulatory systems malfunction, as well as those in chemistry, physics and computer science interested in pursuing careers in biological and medical physics, bioinformatics and systems biology. To that end, the book includes background information and review sections, and chapters on signaling in the immune, endocrine (hormonal) and nervous systems. It has chapters on cancer, apoptosis and gene regulation, and contains chapters on bacteria and viruses. In those chapters not specifically devoted to pathogens, connections between diseases, drugs and signaling are made. Each chapter also features a problem set to facilitate further discussion and understanding.
Modern natural product synthesis
Describes the details of the synthesis routes including unexpected reactions and syntheses. By presenting detailed stories behind the total synthesis developments, including those routes that were unsuccessful the book provides the reader with a better understanding of how other researchers devise their strategy and overcome difficulties in their studies. The contributions in the book have focused on highlighting the research from Japan however it is appealing to researchers and students worldwide. This compilation of cutting-edge natural product synthesis provides high-quality expertise, especially to graduate students and young researchers, regarding research on synthetic organic chemistry. It can be utilized as teaching material in university seminars as well as provide guidance to researchers in the area of total synthesis.
Mobile Robots : The Evolutionary Approach
The design and control of autonomous intelligent mobile robotic systems operating in unstructured changing environments includes many objective difficulties. There are several studies about the ways in which, robots exhibiting some degree of autonomy, adapt themselves to fit in their environments. The application and use of bio-inspired and intelligent techniques such as reinforcement learning, artificial neural networks, evolutionary computation and so forth in the design and improvement of robot designs is an emergent research topic. Researchers have obtained robots that display an amazing slew of behaviours and perform a multitude of tasks. These include perception of environment, planning and navigation in rough terrain, pushing boxes, negotiating an obstacle course, etc.
Memories in Wireless Systems
This book is a guide which treats many components used in mobile communications, and in particular focuses on non-volatile memories. It emerges following the conducting line of the non-volatile memory in the wireless system: On the one hand it develops the foundations of the interdisciplinary issues needed for design analysis and testing of the system. On the other hand it deals with many of the problems appearing when the systems are realized in industrial production. These cover the difficulties from the mobile system to the different types of non-volatile memories.
Medical image synthesis : Methods and clinical applications
Image synthesis across and within medical imaging modalities is an active area of research with broad applications in radiology and radiation oncology. This book covers the principles and methods of medical image synthesis, along with state-of-the-art research. First, various traditional non-learning-based, traditional machine-learning-based, and recent deep-learning-based medical image synthesis methods are reviewed. Second, specific applications of different inter- and intra-modality image synthesis tasks and of synthetic image-aided segmentation and registration are introduced and summarized, listing and highlighting the proposed methods, study designs, and reported performances with the related clinical applications of representative studies. Third, the clinical usages of medical image synthesis, such as treatment planning and image-guided adaptive radiotherapy, are discussed. Last, the limitations and current challenges of various medical synthesis applications are explored, along with future trends and potential solutions to solve these difficulties.
Innovation and Export : The Joint Challenge of the Small Company
This book proposes a joint diagnostic tool for SMEs, highlighting good practices to be mastered in order to simultaneously improve innovation and export performance, in the form of a virtuous circle. Innovation and Export focuses on the integration of innovation and export into the strategic management of SMEs, for which the use of synergies is a powerful lever to overcome any difficulties in mobilizing significant resources.
Individual Criminal Responsibility for Core International Crimes : Selected Pertinent Issues
The media has, of course, played a crucial role in increasing awareness of this concept, especially amongst the general populace. Indeed, the concept has, arguably, a much higher profile today, than ever before in its history. However, the concept of individual criminal responsibility for core inter- tional crimes is neither as straightforward nor as single-facetted, as might appear on first glance. While the general principle behind the concept does not generate too many difficulties, it is in its practical application that the more challenging aspects of the concept are brought to the fore. Each of these ‘challenging - pects’ can also be described as a ‘pertinent issue’ of the concept of individual criminal responsibility for core international crimes.
Handbook of Response to Intervention : The Science and Practice of Assessment and Intervention
Education professionals have traditionally relied on a wait-to-fail formula to identify and assist students experiencing academic difficulties. With the reauthorization of the Individuals with Disabilities Education Improvement Act, however, a unique early-identification tool – known as response to intervention (RTI) – now offers professionals the option of implementing a collaborative, problem-solving tool designed to ensure that all students achieve academic success.
Global Specification and Validation of Embedded Systems : Integrating Heterogeneous Components
Global modelling and validation is required to master the design of systems made of heterogeneous components. These systems are now omnipresent in our life, and they may be found in several domains such as communications (ex. mobile terminals, optical switches), health (e.g. cardiac stimulators, cochlear implants), transportation (ex. automotive and aeronautical), etc. The main difficulties for their design are modelling and validation of the interactions between different components (hardware, software, analogue, RF, optical and micro-mechanical).
Geological Storage of Highly Radioactive Waste : Current Concepts and Plans for Radioactive Waste Disposal
The book describes and assesses current concepts for long-term disposal of highly radioactive waste. Different types of rock are discussed and assessed with respect to practical difficulties in construction of a repository, and the efficiency in isolating radioactive waste. Safety matters are most important and are treated in the respective chapters and in a final, conclusive chapter. Cost issues and related quality matters are discussed for the case of constructing a virgin repository and repositories in the form of converted abandoned mines.
Genomic intelligence : Metagenomics and artificial intelligence
The field of metagenomics has revolutionized our comprehension of microbial diversity and function across various habitats, from the human body to terrestrial and aquatic environments. Simultaneously, advancements in AI have empowered researchers to analyze vast troves of genomic data with unprecedented speed and precision, facilitating new insights into the complex interplay between microorganisms and their surroundings. Provides an overview of metagenomics and discusses the combination of metagenomics and AI and its significant consequences for advancements in science. The chapters examine the approaches, difficulties, and revolutionary uses of AI in metagenomics and provide insight into the convergence of genomics, metagenomics, and AI’s potential to revolutionize diverse fields from healthcare to environmental.
From Assessing to Conserving Biodiversity : Conceptual and Practical Challenges
This book despite increasing communication, accelerating policy and management responses, and notwithstanding improving ecosystem assessment and endangered species knowledge, conserving biodiversity continues to be more a concern than an accomplished task. Why is it so? The overexploitation of natural resources by our species is a frequently recognised factor, while the short-term economic interests of governments and stakeholders typically clash with the burdens that implementing conservation actions imply. But this is not the whole story. This book develops a different perspective on the problem by exploring the conceptual challenges and practical defiance posed by conserving biodiversity, namely: on the one hand, the difficulties in defining what biodiversity is and characterizing that “thing” to which the word ‘biodiversity’ refers to; on the other hand, the reasons why assessing biodiversity and putting in place effective conservation actions is arduous.
