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Marine, Freshwater, and Wetlands Biodiversity
Marine, coastal and wetland habitats are threatened, not only through exploitation, but also by the prospect of climate change – as ocean currents change course, sea levels rise, and rainfall patterns change. Even the once-common cod is now under threat from the combined effects of over-fishing and a dramatic change-induced decrease in the plankton that cod larvae feed on. Meanwhile, coral reefs remain especially vulnerable to rapid sea-level changes exacerbated by the effects of tourism and disease. This book gathers together a wide range of papers reporting on key research into the biodiversity conservation of these critical and increasingly threatened habitats. Collectively these papers provide a snap-shot of the types of problems they are experiencing, and offer a wealth of topical examples which render this volume especially valuable to teachers of courses in marine, freshwater and wetlands ecology, biological conservation and ecological restoration.
Manual of Benirschke and Kaufmanns Pathology of the Human Placenta
Benirschke and Kaufmann's Pathology of the Human Placenta has long been regarded as the gold standard in the field. It is comprehensive and thorough and contains the detail necessary for those in the subspecialties of placental, perinatal and pediatric pathology. However, placentas are relatively common specimens and are not examined primarily by specialists in the field, but by general pathologists. Thus, there is a need for a more practical and concise manual that can be used by pathology trainees and generalists in their daily work. Manual of Benirschke and Kaufmann's Pathology of the Human Placenta will fill that need. The Manual is a practical, user-friendly guidebook for the general pathologist and pathologist in training for everyday, bench-side use. Organized in 27 chapters, the book will discuss placental development, general features, approach to the specimen by macroscopic and microscopic evaluation, all aspects of placental abnormalities and lesions, disease processes and the placenta, legal aspects of the placental examination, future directions and much more. The sections on macroscopic and microscopic evaluations feature quick-reference tables that allow the reader to identify abnormalities, learn the situations where they occur, and refer back to the text for in-depth discussions. Each chapter will end with selected readings from Pathology of the Human Placenta for more detailed discussions, classic recommended readings, as well as an up-to-date bibliography of current literature. The manual features over 444 illustrations, more than 100 of them in full-color. A must-have for every pathologist and pathology resident.
Managing Your Headaches
Frequent headaches seriously affect the lives of millions of sufferers. The result can be lost productivity and income, restrict activity, lower self-esteem, and even social isolation. For many, it takes years to find the appropriate medication to manage your headaches effectively. In Managing Your Headaches, Mark and Leah Green and John Rothrock explain what information you should record for your physician, what a physician is looking for in a neurological examination, and what you should (and should not) do to reduce the frequency and severity of your headaches. They discuss the effects of stress, psychological factors, possible food triggers, and environmental risk factors. The authors explain the symptoms of migraine, cluster, and tension-type headaches as well as less common types. They address common concerns and misconceptions and explain current knowledge about headache causes in understandable terms. The newest, most effective medications and their possible side effects are evaluated. The authors also explain how to prevent rebound headaches from over-medications and how non-medical treatments can be of value. Managing Your Headaches will tell you what you need to know to better control your headaches. Armed with the information in this book, you can be aware of the latest treatment options and can have more productive, informed discussions with your physician.
Managing Failed Anti-Reflux Therapy
This multiauthored text provides information on the pathophysiology of GERD, appropriate medical management, and proper indications for and performance of surgical and endoscopic procedures for GERD. Thousands of patients will experience inadequate relief from medical therapy or will develop complications from their procedures or recurrent or new symptoms afterwards; this text describes in detail the proper evaluation and management of such patients.
Management of Early Stage Breast Cancer : Basics and Controversies
Breast cancer, its causes, early detection and treatment have received considerable attention, since this widespread disease is one of the most important health concerns for women. This book provides a comprehensive overview of the diagnostic and therapeutic aspects of the management of early-stage breast cancer, including essential information on basic topics like pathology, and radiology, as well as the latest developments. Further, it discusses all aspects of surgical care, chemotherapy and radiation therapy, together with the controversies and current management guidelines.
Mammalian Subventricular Zones : Their Roles in Brain Development, Cell Replacement, and Disease
This text provides a comprehensive summary of research and findings that have lead to the current understanding of the subventricular zones. It provides an overview of the roles of subventricular zones in normal development and in disease and a foundation from which current and future studies can be evaluated.
Magnetic Resonance Imaging in Ischemic Stroke
The imaging of stroke has undergone significant changes owing to the rapid progress in imaging technology. This volume, comprising three parts, is designed to provide a comprehensive summary of the current role of MR imaging in patients with ischemic stroke. The first part outlines the clinical presentations of stroke and discusses the diagnostic efficacy and therapeutic impact of MR imaging. The second and third parts form the core of the volume, and are based on a novel approach in that the topic is presented from two very different viewpoints. Part 2 provides a detailed presentation of the distinguishing features of stroke from the radiologist's perspective. By contrast, part 3 addresses the needs of the clinician, documenting specific stroke syndromes and their correlates on MR imaging. The overall aim has been to create a well-illustrated volume with broad appeal that links pathology, radiology and stroke medicine in an informative manner.
Magnetic nanoparticles in human health and medicine : Current medical applications and alternative therapy of cancer
Progress in improving diagnosis by magnetic resonance imaging (MRI) and using non-invasive and non-toxic magnetic nanoparticles for targeted drug delivery. Focusing on cancer diagnosis and therapy, the book covers both fundamental principles and advanced theoretical and experimental research on the magnetic properties, biocompatibilization, biofunctionalization, and application of magnetic nanoparticles in nanobiotechnology and nanomedicine.
Macular Degeneration
Macular Degeneration: Science and Medicine in Practice provides a unique overview of current thinking in the pathogenesis, incidence and treatment of AMD. It includes, for the first time, a synthesis of the views of the world's leading scientists and practitioners regarding retinal biology, basic mechanisms, clinical and pathogenetic processes, and rational approaches to intervention.
Lysosomes
This book summarizes the current state-of-the art knowledge about this unique organelle. It addresses the biogenesis of this compartment, the transport of lysosomal proteins, the role of the lysosomal membrane in lysosomal stability and transport, the function of lysosomal proteases and hydrolases, lysosomal storage disorders, and new concepts on how to treat these diseases.
Living Rivers : Trends and Challenges in Science and Management
All over the world, sustainable river basin management is a leading principle of policy plans and legal instruments for water management (e.g. the European Water Framework Directive). The evidence, however, to underpin the full scope of sustainability is rather scanty. In this book an integrative perspective on trends and challenges in river science and management is demonstrated. The three pillars underneath sustainable water management, ecology, economy and sociology, are elaborated by experts in their fields. A number of papers integrate the current knowledge on the structure, functioning and management of ‘living rivers’. The book includes data and experiences concerning the rivers Allier, Meuse, Rhine, Sava and Tagliamento in Europe and the river Illinois in the USA. Sustainable river basin management asks for un-orthodox rehabilitation programmes and ecosystem based and transboundary management approaches.
Les thérapies ciblées = Targeted therapies
We are at the start of the development of new therapeutic classes, directed against new molecular targets (EGFR, VEGF, IGFR, Rank, etc.) Several diseases such as kidney, colon or breast cancer, GIST, have a natural history now modified thanks to these therapies. This practical book takes stock of the current use of these molecules.
Les techniques de monitorage hémodynamique en réanimation = Hemodynamic monitoring techniques in intensive care
The hemodynamic monitoring of intensive care patients is undergoing major changes. Technological advances such as computerization and miniaturization have made it possible to considerably expand the range of assessment tools available at the bedside. Thus, the approach to cardiovascular monitoring - which was once readily "invasive" and global - is gradually becoming non-invasive and locoregional or even tissue. At the same time, the combined evolution of technology and physiological and pathophysiological concepts now provides the clinician with access to a variety of "functional hemodynamic monitoring". The aim of this book is to provide a better understanding of the interest and the limits of the hemodynamic parameters accessible by current hemodynamic monitoring techniques. It thus aims to ensure that the use of these techniques is perfectly mastered by resuscitators and anesthetists-resuscitators so that patient care is ultimately optimal.
Les cancers ovariens = Ovarian cancers
Deals with ovarian cancers and their therapeutic management. Besides the epithelial tumors which are the most frequent, the rarer tumors, with attenuated malignancy, germ cells or of the ovarian stroma are also studied. Specialists from multiple backgrounds each deliver in their field the most recent knowledge on the fundamental aspects of the disease, its genetic, epidemiological and prognostic characteristics and its pathological peculiarities. Modern means of diagnosis are presented. The surgical technique, including laparoscopy, is detailed at the different stages of the disease. The therapeutic strategy aims to position the surgery and chemotherapy according to the stage. The current place of radiotherapy and isotopic therapies is indicated. Some more specific aspects are discussed, screening, lymph node dissection, the “second look”, intraperitoneal chemotherapy with or without hyperthermia, treatment of the elderly, monitoring after treatment… as well as the emergence of targeted therapies.
Leptomeningeal Metastases
Leptomeningeal Metastases provides the reader with an overview of the state-of-the-art therapy for the leptomeningeal patient with additional information on epidemiology, symptom management, new clinical trials, and current basic research in animal models for experimental therapies. "Leptomeningeal metastases remains a devastating manifestation of hematologic malignancies and solid tumors. Leading figures in the field review the pathophysiology and clinical consequences of this process. State-of-the-art treatment strategies are presented highlighting advances in current management."
Le dépistage du cancer du sein : un enjeu de santé publique = Breast cancer screening: a public health issue
Fifteen years after the first experiments, the breast cancer screening program was rolled out in France in 2004. It is aimed at more than eight million women aged 50 to 74. Public health action on such a scale is exemplary in Europe and especially in France where the health system is not centralized. The new edition of this book takes stock of the current state of the program and its initial results. It updates technical and radiological aspects, assessment indicators, communication and forensic problems and finally the progress of foreign programs. The history of the French program is detailed from the 1990s until 2006, with the publication of the latest version of the specifications by the Directorate General of Health. The short and medium term objectives are re-specified: to increase the participation of women, to retain them and to further improve the quality of practices. The challenge is to combine the performance of screening and therapeutic management to finally achieve a clear reduction in mortality, which has remained stable for twenty years.
Le dépistage du cancer colorectal : État des lieux et perspectives = Colorectal cancer screening: Current status and perspectives
Prevention and screening are two major challenges for Public Health to reduce cancer mortality in our country. Screening for colorectal cancer is therefore quite exemplary. The number one cancer in both sexes in France, its incidence continues to increase due to the aging of the population. Its mortality remains high, in the order of fifty percent, despite the major therapeutic advances made in recent years. Preceded by a precancerous lesion - the adenomatous polyp, which can be removed by colonoscopy - colorectal cancer is also curable at the early stage. Finally, it can be the subject of a screening strategy, the impact of which has been demonstrated today on the reduction in mortality, when it is detected before any symptom by a simple test for blood in the stool followed by , in case of positivity, by a total colonoscopy. This book takes stock of the scientific rationale and the state of play of organized colorectal cancer screening in France. It is also an opportunity to discuss emerging techniques and strategies that can help improve the results of this screening if they prove their superiority over the current strategy. Intended primarily for doctors, this book is also intended for healthcare professionals and all those who, concerned about their health, have a proactive attitude in terms of screening and preventing this cancer.
Le cancer du sein = Breast cancer
The reader will find there both a synthetic summary of the current state of knowledge of epidemiology, risk factors and pathological aspects as well as a presentation of the surgical aspects, in particular, of the new approach that constitutes the sentinel node procedure. Radiotherapy, in a practical view, is divided into essential clinical questions. The medical treatment is then discussed according to the different situations encountered on a daily basis. Particular attention is of course paid to recent data both with the contribution of hormone therapy and targeted therapies. Finally, the symptomatic treatments and especially the psychological care of these patients are not forgotten.
Laparoscopic Urologic Surgery in Malignancies
The horizons of laparoscopic surgery are expanding, such that the overwhelming majority of abdominal urologic procedures have now been performed laparoscopically. In some of these procedures, the laparoscopic alternative has been demonstrated to be superior to its open counterpart; in others comparative analyses are ongoing; and in yet others, only the initial forays into minimally invasive surgery have been undertaken. This book sets out to collate the current body of knowledge on laparoscopic urology under one cover. The authors are respected experts in the field and have provided concise, thoughtful updates on their respective topics. The information contained in this volume will help urologists to increase their laparoscopic knowledge and skills.
Lake Taihu, China : Dynamics and Environmental Change
There are many shallow lakes in the world. Many of them play an important socio-economic role as contributors to the drinking water supply, in flood attenuation, fisheries and recreation activities. Because of the current anthropogenic changes in the environment, such lakes rapidly respond to eutrophication and swamping. It is often hard to address these issues because many changes in the ecosystems of shallow lakes are associated with little studied physical processes. This interaction between the aquatic biota and the physical and chemical environment increases the complexity of shallow lake ecosystems. Lake Taihu, located in the delta of Yangtze River, is a typical large, shallow eutrophic lake with area of 2338 km2 and maximum depth of less than 3m . This book provides basic data on various aspects of this lake and summarizes research work on the interaction between its ecology and physical limnology. It will be a reference for teachers and students of freshwater ecology and biology, the aquatic environment in general, and, most strikingly, for all those interested in physical limnology.
