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Big data analytics and machine intelligence in biomedical and health informatics : Concepts, methodologies, tools and applications

Provides coverage of developments and state-of-the-art methods in the broad and diversified data analytics field and applicable areas such as big data analytics, data mining, and machine intelligence in biomedical and health informatics. Covers the latest advances and developments in health informatics, data mining, machine learning, and artificial intelligence. They have been organized with respect to the similarity of topics addressed, ranging from issues pertaining to the Internet of Things (IoT) for biomedical engineering and health informatics, computational intelligence for medical data processing, and Internet of Medical Things??(IoMT).

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Complex Systems Science in Biomedicine

Complex Systems Science in Biomedicine covers the emerging field of systems science involving the application of physics, mathematics, engineering and computational methods and techniques to the study of biomedicine including nonlinear dynamics at the molecular, cellular, multi-cellular tissue, and organismic level. With all chapters helmed by leading scientists in the field, Complex Systems Science in Biomedicine's goal is to offer its audience a timely compendium of the ongoing research directed to the understanding of biological processes as whole systems instead of as isolated component parts.

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Chitosan : properties and applications in bioengineering

Presents a review of chitosan, including information regarding its structure, main properties, available sources, extraction, and processing techniques. It presents the different applications of chitosan as a biomaterial in fields such as medicine and the agricultural, cosmetology, pharmaceutical, and food industries to have readers obtain a more technical vision of the current use of this biopolymer.

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Biopharmaceutical manufacturing progress, trends and challenges

Source of the latest innovative research and technical development in biomanufacturing systems. It is organised into 2 parts: 1) Manufacturing of recombinant therapeutic proteins (e.g. therapeutic antibodies, biosimilars/biogenerics) and 2) Manufacturing aspects of cell and gene therapy. Each with selected chapters on the following topics for both up- and downstream, such as: Advanced process strategies, especially continuous manufacturing, Advanced culture techniques, especially single-use systems, Process transfer, scale-up/scale-down models, Processing advances/Manufacturing productivity/efficiency, Model-assisted process understanding and development/Digital Twins, Process controls and analytics, Quality control, Quality by design, Facility design and full-scale commercial systems, manufacturing technology innovation.

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Biomedical applications and toxicity of nanomaterials

Covers the recent trends on the biological applications of nanomaterials, methods for their preparation, and techniques for their characterization. Further, the book examines the fundamentals of nanotoxicity, methods to assess the toxicity of engineered nanomaterials, approaches to reduce toxicity during synthesis. It also provides an overview of the state of the art in the application of Artificial intelligence-based methodologies for evaluation of toxicity of drugs and nanoparticles. The book further discusses nanocarrier design, routes of various nanoparticle administration, nano based drug delivery systems, and the toxicity challenges associated with each drug delivery method. It presents the latest advances in the interaction of nanoparticles with the cellular environment and assess nanotoxicity of these engineered nanoparticles. The book also explores the comparative and mechanistic genotoxicity assessment of the nanomaterials. This book is useful source of information for industrial practitioners, policy makers, and other professionals in the fields of toxicology, medicine, pharmacology, food, and drugs.

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Biomaterials : An Introduction

Biomaterials, an Introduction is intended as a general introduction to the uses of artificial materials in the human body for the purposes of aiding healing, correcting deformities, and restoring lost function. Enhancing on the field developments since the successful last edition, Biomaterials, an Introduction continues in its tradition as an outgrowth of an undergraduate course for senior students in biomedical engineering developed by the authors With 60 years of combined experience, the authors have emphasized the fundamental materials science, structure-property relationships and biological responses as a foundation for a wide array of biomaterials applications.

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Biomarkers as targeted herbal drug discovery : A pharmacological approach to nanomedicines

Looks at the applications of biomarkers as important tools for herbal drug discovery, presenting research on phytoconstituents with advanced nanotechnological applications for healthcare benefits. Herbal drug discovery based on biomarkers is an emerging area in complementary and alternative medicine that has tremendous potential in healthcare. Conventional medications have limited efficacy and high toxicity, whereas herbal drugs are said to provide wide structural diversity that is not usually seen with conventional/synthetic drug molecules. Recognition of various herbal constituents, such as terpenoids, fatty acids, flavonoids and steroids, are well explored in the management and treatment of various disorders in this volume. These agents target various biomarkers such as nitric oxide (NO), cytokines, chemokines, adhesion molecules, NF- kβ, lipoxygenase (LOX), and arachidonic acid. Reviews the literature on inflammatory biomarkers in the treatment of diseases Looks at the development of herbal drug discovery based on biomarkers Explores emerging concepts of nanomedicines for herbal drug delivery Takes an interdisciplinary approach, with application to disciplines related to medical, pharmaceutical, biotechnological, Ayurvedic, Unani and biomedical engineering fields

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Advances in Metallodrugs : Preparation and Applications in Medicinal Chemistry

This book is organized into 12 important chapters that focus on the progress made by metal-based drugs as anticancer, antibacterial, antiviral, anti-inflammatory, and anti-neurodegenerative agents, as well as highlights the application areas of newly discovered metallodrugs. It can prove beneficial for researchers, investigators and scientists whose work involves inorganic and coordination chemistry, medical science, pharmacy, biotechnology and biomedical engineering

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Advanced soft electronics in biomedical engineering : materials, manufactures, and applications

Presents the latest advances in soft electronics in biomedical engineering and its potential applications in various biomedical fields. Provide comprehensive coverage of how soft electronics are used in diagnostics and monitoring, medical therapy, neural engineering, and wearable and implantable systems. In particular, some emerging research areas such as advanced soft robotics, fiber sensing technologies, and power optimization strategies are explored. In addition, the book highlights international standardization activities in wearable technologies and implantable bioelectronics.

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Advanced Bioimaging Technologies in Assessment of the Quality of Bone and Scaffold Materials : Techniques and Applications

This book provides a perspective on the current status of bioimaging technologies developed to assess the quality of musculoskeletal tissue with an emphasis on bone and cartilage. It offers evaluations of scaffold biomaterials developed for enhancing the repair of musculoskeletal tissues. These bioimaging techniques include micro-CT, nano-CT, pQCT/QCT, MRI, and ultrasound, which provide not only 2-D and 3-D images of the related organs or tissues, but also quantifications of the relevant parameters. The advance bioimaging technologies developed for the above applications are also extended by incorporating imaging contrast-enhancement materials.

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Brain and Human Body Modeling : Computational Human Modeling at EMBC 2018

This book describes modern applications of computational human modeling with specific emphasis in the areas of neurology and neuroelectromagnetics, depression and cancer treatments, radio-frequency studies and wireless communications. Special consideration is also given to the use of human modeling to the computational assessment of relevant regulatory and safety requirements. Readers working on applications that may expose human subjects to electromagnetic radiation will benefit from this book’s coverage of the latest developments in computational modelling and human phantom development to assess a given technology’s safety and efficacy in a timely manner.

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Artificial Intelligence Applications for Health Care

Covers topics on health care and artificial intelligence. Data sets related to biomedical signals (ECG, EEG, EMG) and images (X-rays, MRI, CT) are explored, analyzed, and processed through different computation intelligence methods. Applications of computational intelligence techniques like artificial and deep neural networks, swarm optimization, expert systems, decision support systems, clustering, and classification techniques on medial datasets are explained. Survey of medical signals, medial images, and computation intelligence methods are also provided.

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Applications of artificial intelligence in business, education and healthcare

Highlights the opportunities and challenges of artificial intelligence in business, education, and healthcare from institutional, environmental, social perspectives Includes empirical and theoretical research Presents applications of Artificial Intelligence in Business, Education and Healthcare

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Anatomy ontologies for bioinformatics : Principles and practice

This book provides a timely and first-of-its-kind collection of contributed chapters on anatomy ontologies. It is interdisciplinary in its approach, bringing together relevant expertise from computing and biomedical studies, and covering both theoretical and applied aspects, with an emphasis on newer work relevant to the emerging Semantic Web.

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Biomaterials and engineering for implantology: in medicine and dentistry

Biomaterials are composed of metallic materials, ceramics, polymers, composites and hybrid materials. Biomaterials used in human beings require safety regulations, toxicity, allergic reaction, etc. When used as implantable materials their biological compatibility, biomechanical compatibility, and morphological compatibility must be acessed. This book explores the design and requirements of biomaterials for the use in implantology.

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Applications of biomedical engineering in dentistry

Applications of Biomedical Engineering in Dentistry offers readers a valuable overview of recent advances in biomedical engineering, as applied to the modern dentistry.

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Advanced dental biomaterials

Advanced Dental Biomaterials is an invaluable reference for researchers and clinicians within the biomedical industry and academia. The book can be used by both an experienced researcher/clinician learning about other biomaterials or applications that may be applicable to their current research or as a guide for a new entrant into the field who needs to gain an understanding of the primary challenges, opportunities, most relevant biomaterials, and key applications in dentistry.

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Advanced bioceramics : Properties, processing, and applications

Offers a comprehensive view of properties and processing of bioceramics. Highlights applications in dentistry, orthopaedic and maxillofacial implants, and regenerative and tissue engineering. Covers ISO/ASTM specifications such as processing, clinical applications, recycling/reuse and disposal standards.

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3D Printing in Oral Health Science : Applications and Future Directions

Equips readers with a sound understanding of contemporary clinical applications in all fields of dentistry and their future directions. In the last few years, the development of 3D printing for medical and dental applications has increased tremendously. Advancements in 3D printing create the possibility of customized products, savings on small-scale productions, ease of sharing and processing of patient image data, and educational up-gradation. Looking at the dental specialties, it is evident that 3D printing has applications in all aspects of oral health science including prosthodontics, oral surgery, periodontics, endodontics, and orthodontics. This book will cover all major fields in dentistry and will help the practitioner in the process of decision-making and apply concepts in clinical or laboratory practice. It is based on current scientific evidence to provide readers with an up-to-date contemporary underst

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3D printing in oral & maxillofacial surgery

A comprehensive guide to 3D printing and 3D bioprinting methods and their application in oral and maxillofacial surgeries. Among the 3D printing methods considered are fused deposition modeling, selective laser sintering, photopolymer jetting, powder binder printing, and stereolithography, while the coverage of 3D bioprinting encompasses inkjet, microextrusion, and laser techniques. In each case, the relevance of the technique to oral and maxillofacial surgery is explained. In addition, the available inks and bioinks for 3D printing are reviewed. The roles of soft and hard tissue printing in oral and maxillofacial tissue engineering and the use of 3D printing in multi- and interfacial tissue engineering are then examined in depth. The particular value of 3D printing in the treatment of critically sized defects is discussed separately. Finally, up-to-date information is provided on guided tissue/bone regeneration using 3D printing. The book will be of interest to both oral and maxillofacial surgeons and biomedical engineers.

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