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Mammalian and Avian Transgenesis : New Approaches
Mammalian and Avian Transgenesis presents a collection of novel methods for the production of a wide range of transgenic animals. The manual focuses largely on mice, but also contains protocols for successful transgenesis in rats, cows, pigs and birds. The manual provides detailed, step-by-step protocols covering all aspects of the production of transgenic animals, including the use of lentiviral vectors in gene transfer, intracytoplasmic sperm injection, nuclear transfer, large insert transgenesis, conditional gene expression systems, the use of reporter genes in transgenesis and transgenesis in large animals and birds. The text is supplemented by superb color photos. While the focus is on newly established techniques, the fundamental methods of transgenesis are also covered for those new to the field. Thus this manual is perfectly suited for those wishing to adopt new technologies in transgenesis.
Low-Dose Radiation Effects on Animals and Ecosystems : Long-Term Study on the Fukushima Nuclear Accident
Brings together the works of radiation biologists and ecologists to provide reliable radioecology data and gives insight into future radioprotection. The book examines the environmental pollution and radiation exposure, and contains valuable data from abandoned livestock in the ex-evacuation zone and from wild animals including invertebrates and vertebrates, aqueous and terrestrial animals, and plants that are subjected to long-term exposure in the area still affected by radiation. It also analyzes dose evaluation, and offers new perspectives gained from the accident, as well as an overview for future studies to promote radioprotection of humans and the ecosystem.
Complexity in landscape ecology
Interactions matter. To understand the distributions of plants and animals in a landscape you need to understand how they interact with each other, and with their environment. The resulting networks of interactions make ecosystems highly complex. Recent research on complexity and artificial life provides many new insights about patterns and processes in landscapes and ecosystems. This book provides the first overview of that work for general readers. It covers such topics as connectivity, criticality, feedback, and networks, as well as their impact on the stability and predictability of ecosystem dynamics. With over 60 years of research experience of both ecology and complexity, the authors are uniquely qualified to provide a new perspective on traditional ecology.
Comparative Hepatitis
This volume reviews today’s knowledge about hepatitis with emphasis on comparative aspects between hepatitis in humans and animals, but also between different etiological agents. This particular viewpoint makes the book relevant for scientists from both human and veterinary medicine, gastroenterologists, pathologists, virologists and students of human and veterinary medicine.
Common Chinese materia medica ; Vol.10
Records 5 species of resin, 74 species of animals, 41 species of minerals and fossils. There are resins such as Liquidambar orientalis, Commiphore myrrha, Boswellia carterii, Garcinia hanburyi; animals such as Solenognathus hardwickii, , Cervus nippon, Scolopendra subspinipes, Cryptotympana pustulata, Agkistrodon acutus, Bombyx mori, Collocalia esculenta, Moschus moschiferus, Hippocampus kelloggi, Gekko gekko; minerals and fossils such as mercury, gypsum, alum, mirabilite, cinnabar, actinolite, calomel, keel, dens draconis, lithodes, fossilia spiriferis.
Cephalopods Present and Past : New Insights and Fresh Perspectives
Cephalopods are diverse, highly developed molluscs capable of swimming and jet propulsion. These animals are an important component of present-day marine ecos- tems throughout the world and comprise approximately 900 species. They also have an extraordinary fossil record, extending back to the Cambrian Period, with as many as 10,000 extinct species. Throughout their long history, they have experienced sp- tacular radiations and near-total extinctions. Because of their superb fossil record, they also serve as ideal index fossils to subdivide geologic time. This book touches on many of these themes, and it treats both fossil and present-day cephalopods.
Cell-Cell Channels
The biological sciences are dominated by the idea that cells are the functionally autonomous, physically separated, discrete units of life. This concept was propounded in the 19th century by discoveries of the cellular structuring of both plants and animals. Moreover, the ap parent autonomy of unicellular eukaryotes, as well as the cellular basis of the mammalian brain (an organ whose anatomy for a long while defied attempts to validate the idea of the cellular nature of its neurons), seemed to provide the final conclusive evidence for the completeness of *cell theory', a theory which has persisted in an almost dogmatic form up to the present day. However, it is very obvious that there are numerous observations which indicate that it is not the cells which serve as the basic units of biological life but that this property falls to some other, subcellular assemblage. To deal with this intricate problem concerning the fundamental unit of living matter, we proposed the so-called Cell Body concept which, in fact, devel ops an exceedingly original idea proposed by Julius Sachs at the end of the 19th century. In the case of eukaryotic cells, DNA-enriched nuclei are intimately associated with a microtubular cytoskeleton. In this configuration—as a Cell Body—these two items comprise the fundamental functional and struc tural unit of eukaryotic living matter. The Cell Body seems to be inherent to all cells in all organisms.
Cancer : Cell Structures, Carcinogens and Genomic Instability
Tumors can be induced by a variety of physical and chemical carcinogens. The resulting tumor cells are usually abnormal in their morphology and behavior and transmit their abnormalities to their daughter tumor cells. Most theories of the pathogenesis of tumors suggest that carcinogens in some way cause alterations either of the genomes or of inheritable patterns of gene expression in normal cells, which then cause morphological and behavioral changes. This volume presents a collection of articles aimed at the question by what genetic or epigenetic mechanisms carcinogens can cause morphological abnormalities of tumor cells. It includes reviews of cellular targets of known carcinogens, and presents varying viewpoints of how morphological abnormalities and the actions of carcinogens might be related.
Calcium Signalling and Disease : Molecular Pathology of Calcium
This topic is a new entry in the area of cellular calcium signaling: yet, it now spans the entire area, with discoveries that cover both genetic and acquired pathologies, even offering glimpses in the direction of therapy.Cellular calcium homeostasis, and thus calcium signalling, is mainly regulated by membrane intrinsic proteins and calcium sensor proteins. Both classes may be involved in pathological processes that affect both human and animals, ranging from common and important diseases (e.g. migraine, diabetes, epilepsia, manic depression, infertility, various types of cancer, Alzheimer’s disease, muscular dystrophy) to rare genetic conditions (e.g., a number of genetic heart conditions, autoimmune retinopathies, night blindness, hereditary amyloid polyneuropathy, malignant hyperthermia, cerebellar ataxia, atherothrombotic disease).
Brodmann's : Localisation in the Cerebral Cortex
It is one of the major "classics" of the neurological world. Even today it forms the basis for so-called "localisation" of function in the cerebral cortex. Brodmann's "areas" are still used to designate functional regions in the cortex, the part of the brain that brings the world that surrounds us into consciousness, and which governs our responses to the world. For example, we use "area 4" for the "motor" cortex, with which we control our muscles, "area 17" for "visual" cortex, with which we see, and so on. This nomenclature is used by neurologists and neurosurgeons in the human context, as well as by experimentalists in various animals. Indeed, Brodmann's famous "maps" of the cerebral cortex of humans, monkeys and other mammals must be among the most commonly reproduced figures in neurobiological publishing. The most famous of all is that of the human brain. There can be few textbooks of neurology, neurophysiology or neuroanatomy in which Brodmann is not cited, and his concepts pervade most research publications on systematic neurobiology.
Branching Morphogenesis
Branching morphogenesis, the creation of branched structures in the body, is a key feature of animal and plant development. This book brings together, for the first time, expert researchers working on a variety of branching systems to present a state-of-the-art view of the mechanisms that control branching morphogenesis. Systems considered range from single cells, to blood vessel and drainage duct systems to entire body plans, and approaches range from observation through experiment to detailed biophysical modelling. The result is an integrated overview of branching.
Bioterrorism and Infectious Agents : A New Dilemma for the 21st Century
Since the terrorist attack on the United States on September 11, 2001 and subsequent cases of anthrax in Florida and New York City, attention has been focused on the threat of b- logical warfare and bioterrorism. Biological warfare agents are de?ned as “living org- isms, whatever their nature, or infected material derived from them, which are used for h- tile purposes and intended to cause disease or death in man, animals and plants, and depend for their efforts on the ability to multiply in person, animal or plant attacked.” Biological warfare agents may be well suited for bioterrorism to create havoc and terror in a civilian population, because they are cheap and easy to obtain and dispense. Infectious or contagious diseases have played a major part in the history of warfare – deliberately or inadvertently – in restricting or assisting invading armies over the centuries. In 1346, the Tartars catapulted plaque-infected bodies into Kaffa in the Crimea to end a 3-year siege. Blankets contaminated with smallpox to infect North American Indians were used by British forces in the 18th century. More recently, the Japanese released ?eas infected with plaque in Chinese cities in the 1930s and 1940s. Biological research programs for both offensive and defensive strategies have been developed by the United States, Britain, the former Soviet Union, and Canada; several other nations are thought to have such programs.
Bio-mechanisms of swimming and flying ; Fluid dynamics, biomimetic robots, and sports science
This book follows "Bio-mechanisms of Animals in Swimming and Flying" published in 2004 including 11 chapters. This time, the book includes 31 chapters on the latest researches into natural autonomous systems and locomotion in both flying and swimming organisms. The area of sports science such as analysis and simulation of human swimming is newly added. The computational frameworks for the modeling, simulation and optimization of animals in swimming and flying demonstrate an important role in the progress of interdisciplinary work in the fields of biology and engineering. An innovative technology is exhibited for the flight of an insect size micro air vehicle. Neuronal science is not only unveiling the locomotion mechanisms of swimming in fish from the aspect of the neuronal activities, but also applied to underwater biomimetic robots. The interdisciplinary works are exhibited in the fields of biology and engineering, yielding real-world benefits in innovative technologies.
Biological Invasions
This new volume on Biological Invasions deals with both plants and animals. It differs from previous books on the subject by extending from the level of individual species to an ecosystem and global level. Topics of highest societal relevance, such as the impact of genetically modified organisms, are interlinked with more conventional ecological aspects, including biodiversity. The combination of these approaches is new and makes compelling reading for researchers and environmentalists. The book’s 22 chapters cover a huge range of subjects relevant to the field. These include pathways of biological invasions (e.g. ballast water, waterways), traits of successful invaders (e.g. chemical weapons, empty niches), and patterns of invasion and invasibility, such as man-induced predisposition by fire, land use and eutrophication, and the role of climate change.
Biological adhesives
Many plants, animals, and microbes use adhesive polymers and structures to attach to inert substrates, to each other, or to other organisms. This is the first major review that brings together research on many of the well-known biological adhesives. Emphasizing the diversity of biological adhesives and associated adhesion processes, it deals with bacteria, fungi, algae, and marine and terrestrial animals. It bridges a variety of disciplines including biochemistry, molecular biology, biomechanics, bioengineering, microbiology, organism structure and function, and ultrastructure. As we learn more about the molecular and mechanical properties of these adhesives, we begin to understand why they adhere so well and how they develop cohesive strength. With this understanding comes the prospect of developing synthetic or semi-synthetic adhesives with broad applications in areas such as medicine, dentistry, and biotechnology. The book is suitable for both industrial and academic researchers.
Auditory Perception of Sound Sources
Auditory Perception of Sound Sources covers higher-level auditory processes that are perceptual processes. The chapters describe how humans and other animals perceive the sounds that they receive from the many sound sources existing in the world. This book will provide an overview of areas of current research involved with understanding how sound-source determination processes operate. This book will focus on psychophysics and perception as well as being relevant to basic auditory research.
Asymmetric Cell Division
Cell biologists have recently become aware that the asymmetry of cell division is an important regulatory phenomenon in the fate of a cell. During development, cell diversity originates through asymmetry; in the adult organism asymmetric divisions regulate the stem cell reservoir and are a source of the drift that contributes to the aging of organisms with renewable cell compartments. Because of the concept of semi-conservative DNA synthesis, it was thought that the distribution of DNA between daughter cells was symmetric. The analysis of the phenomenon in cells during mitosis, however, revealed the asymmetry in the distribution of the genetic material that creates the drift contributing to aging of mammals. On the other hand, cancer cells can originate from a deregulation of asymmetry during mitosis in particular during stem cell expansion. The book describes the phenomenon in different organisms from plants to animals and addresses its implications for the development of the organism, cell differentiation, human aging and the biology of cancers.
Aquatic Biodiversity II : The Diversity of Aquatic Ecosystems
The present book comprises a unique collection of primary research papers spanning a wide range of topics in aquatic biodiversity studies, and including a first global assessment of specific diversity of freshwater animals. The book also presents a section on the interaction between scientists and science policy managers
Antarctic ecosystems : Environmental contamination, climate change, and human impact
This volume provides an overview of climate change data, its effects on the structure and functioning of Antarctic ecosystems, and the occurrence and cycling of persistent contaminants. It discusses the unique physico-chemical characteristics of the Antarctic environment, ecophysiological adaptations of terrestrial and marine organisms, the transfer of contaminants in pelagic and neritic food chains and the possible consequences for animals at higher trophic levels.
Animals and the shaping of modern medicine : One health and its histories
This book breaks new ground by situating animals and their diseases at the very heart of modern medicine. In demonstrating their historical significance as subjects and shapers of medicine, it offers important insights into past animal lives, and reveals that what we think of as ‘human’ medicine was in fact deeply zoological.Each chapter analyses an important episode in which animals changed and were changed by medicine. Ranging across the animal inhabitants of Britain’s zoos, sick sheep on Scottish farms, unproductive livestock in developing countries, and the tapeworms of California and Beirut, they illuminate the multi-species dimensions of modern medicine and its rich historical connections with biology, zoology, agriculture and veterinary medicine. The modern movement for One Health – whose history is also analyzed – is therefore revealed as just the latest attempt to improve health by working across species and disciplines.
