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Lantibiotics as alternative therapeutics
Explores alternative therapeutics, lantibiotics and other novel drugs. This book provides concrete information to readers regarding lantibiotics and various types of antimicrobial peptides with their mode of actions in treating various multidrug resistant organisms. It explains various techniques that are involved in analyzing antimicrobial peptides and their mode of actions. The development of antibiotic resistance has now reached a point of crisis where innovative methods and application of novel compounds and methods are required to prevent the spread of drug resistant infections.
Chemical Biology and Drug Discovery
Gives the reader, through the specific selection of chemical-biological techniques and concepts, the necessary tools to be able to develop new ways of thinking and thus new therapeutic options in the complex field of chemical biology and drug development. The stated aim of this book is to provide concrete solutions and inspiration to students, (post)graduate students, and experienced scientists at universities as well as in industry in their problems.
Complexity Theory : Exploring the Limits of Efficient Algorithms
Complexity theory is the theory of determining the necessary resources for the solution of algorithmic problems and, therefore, the limits of what is possible with the available resources. An understanding of these limits prevents the search for non-existing efficient algorithms. This textbook considers randomization as a key concept and emphasizes the interplay between theory and practice: New branches of complexity theory continue to arise in response to new algorithmic concepts, and its results - such as the theory of NP-completeness - have influenced the development of all areas of computer science. The topics selected have implications for concrete applications, and the significance of complexity theory for today's computer science is stressed throughout.
Artificial neural network-based optimized design of reinforced concrete structures
Introduces AI-based Lagrange optimization techniques that can enable more rational engineering decisions for concrete structures while conforming to codes of practice. It shows how objective functions including cost, CO2 emissions, and structural weight of concrete structures are optimized either separately or simultaneously while satisfying constraining design conditions using an ANN-based Lagrange algorithm. Any design target can be adopted as an objective function. Many optimized design examples are verified by both conventional structural calculations and big datasets. Uniquely applies the new powerful tools of AI to concrete structural design and optimization Multi-objective functions of concrete structures optimized either separately or simultaneously Design requirements imposed by codes are automatically satisfied by constraining conditions Heavily illustrated in color with practical design examples
Abstract Computing Machines : A Lambda Calculus Perspective
The book addresses ways and means of organizing computations, highlighting the relationship between algorithms and the basic mechanisms and runtime structures necessary to execute them using machines. It completely abstracts from concrete programming languages and machine architectures, taking instead the lambda calculus as the basic programming and program execution model to design various abstract machines for its correct implementation. The emphasis is on fully normalizing machines based on full-fledged beta-reductions as essential prerequisites for symbolic computations that treat functions and variables truly as first-class objects. Their weakly normalizing counterparts are shown to be functional abstract machines that sacrifice the flavors of full beta-reductions for decidedly simpler runtime structures and improved runtime efficiency. Further downgrading of the lambda calculus leads to classical imperative machines that permit side-effecting operations on the runtime environment.
Advanced Nanomaterials
Covers synthesis, characterization, and applications of diverse types of nanomaterials. Specifically, it describes carbon, graphene, and graphene oxide-based nanomaterials and their use for environmental remediation. Nanomaterials for concrete coating applications and advances in the processing of high-entropy alloys by means of mechanical alloying are also covered. Subsequently, the use of nanomaterials in endodontics and the use of nanotechnology strategies to enhance restorative resin-based dental nanomaterials are reported.
Buildings for Education: A Multidisciplinary Overview of The Design of School Buildings
This book presents theoretical and practical research relating to the vast, publicly financed program for the construction of new schools and the reorganization of existing educational buildings in Italy.
Material Modeling in Finite Element Analysis
Presents some specific problems including the metal-forming process, combustion room, Mullins effect of rubber tires, viscoelasticity of liver soft tissues, small punch test, tunnel excavation, slope stability, concrete slump test, orthodontic wire, and piezoelectric microaccelerometer.
LRFD Bridge Design : Fundamentals and Applications
Examines and explains material from the 9th edition of the AASHTO LRFD Bridge Design Specifications, including deck and parapet design, load calculations, limit states and load combinations, concrete and steel I-girder design, bearing design, and more. With increased focus on earthquake resiliency, two separate chapters– one on conventional seismic design and the other on seismic isolation applied to bridges– will fully address this vital topic. The primary focus is on steel and concrete I-girder bridges, with regard to both superstructure and substructure design. / Includes several worked examples for a project bridge as well as actual bridges designed by the author / Examines seismic design concepts and design details for bridges / Presents the latest material based on the 9th edition of the LRFD Bridge Design Specifications / Covers fatigue, strength, service, and extreme event limit states / Includes numerous solved problems and exercises at the end of each chapter to illustrate the concepts presented
Composite structures of steel and concrete : Beams, slabs, columns and frames for buildings
Provides an introduction to the theory and design of composite structures of steel and concrete. Material applicable to both buildings and bridges is included, with more detailed information relating to structures for buildings. Throughout, the design methods are illustrated by calculations in accordance with the Eurocode for composite structures, EN 1994, Part 1-1, 'General rules and rules for buildings' and Part 1-2, 'Structural fire design', and their cross-references to ENs 1990 to 1993.
Civil Engineering Materials for Transportation Infrastructure
Includes the fundamental mechanical and physical properties of materials; properties, tests, and gradation designs of aggregates; production, composition, hydration, properties, and tests of lime and cement; composition, tests, and design of cement concrete; mechanisms, properties, and design of inorganic binder stabilized material; properties, tests, and grading of asphalt; composition, properties, tests, and designs of asphalt mixture; and properties, treatments, tests, and selections of steel.
Civil engineering materials : From theory to practice ; 1st ed.
Presents the state-of-the-art in civil engineering materials, including the fundamental theory of materials needed for civil engineering projects and unique insights from decades of large-scale construction in China. The title includes the latest advances in new materials and techniques for civil engineering, showing the relationship between composition, structure and properties, and covering ultra-high-performance concrete and self-compacting concrete developed in China. This book provides comprehensive coverage of the most commonly used, most advanced materials for use in civil engineering. This volume consists of eight chapters covering the fundamentals of materials, inorganic cementing materials, Portland cement concrete, bricks, blocks and building mortar, metal, wood, asphalt and polymers.
Civil engineering materials
Concentrates on demonstrating methods to obtain, analyse and use information rather than focusing on presenting large amounts of data. Beginning with basic properties of materials, it moves on to more complex areas such as the theory of concrete durability and corrosion of steel.
CEB-FIP Model code 1990 : Design code
This document is a comprehensive design code for concrete. It is the result of a comprehensive revision to the original model code of 1978, which was produced jointly by the Comite Euro-International du Beton (CEB) and the Federation Internationale de la Precontrainte (FIP). Model Code 1990 has more detailed guidelines and explanations than national codes and can be used as a basis for them. It has already influenced the codification work that is being carried out both nationally and internationally and will continue to do so. With the publication of Eurocode 2: Part 1 as a draft pre-standard, this document is a useful reference during the consultative period before Eurocode 2 becomes a European standard. It may be of use to anyone involved in codification work on concrete.
Cathodic protection for reinforced concrete structures
For specialist contractors, large consultants and owners of corrosion damaged structures, and looks at international experience with this technique. It examines why corrosion is occurring, the differences in the application of CP with the stark dichotomy in its success and failure, and finally ways in which its performance can be improved on future installations.
Bridge Design : Concepts and Analysis
Provides a unique approach, combining the fundamentals of concept design and structural analysis of bridges in a single volume. The book provides insights into conceptual design with concrete, steel or composite bridge solutions as alternatives.
Blast effects on buildings
Provides the latest practical guidance on designing buildings to optimise their resilience to blast loading. Focused specifically on the design of commercial buildings, it is an indispensible guide to help engineers reduce the risks posed to building occupants and businesses from terrorist and other explosions. This book provides the engineer with a single and comprehensive source of reference for all the main elements of blast engineering design in modern practice. Industry-accepted methods for the design of glazing to resist blast loading are published for the first time, as well as a new chapter on hostile vehicle mitigation techniques. Guidance on structural steelwork and reinforced concrete design is extended and enhanced, supplemented with material on design in new materials such as steel-concrete-steel composites, this latter addition being published for the first time.
Artificial intelligence in mechatronics and civil engineering : Bridging the gap
Recent studies highlight the application of artificial intelligence, machine learning, and simulation techniques in engineering. This book covers the successful implementation of different intelligent techniques in various areas of engineering focusing on common areas between mechatronics and civil engineering. The power of artificial intelligence and machine learning techniques in solving some examples of real-life problems in engineering is highlighted in this book. The implementation process to design the optimum intelligent models is discussed in this book.
Artificial intelligence and machine learning techniques for civil engineering
Offers state-of-the-art contributions in the area of AI and its applications in the field of civil engineering presenting methods and implementation of AI and machine learning in multiple facets of civil engineering
Appraisal and repair of of building structures
This book is a practical guide to the detection and remedy of faults in claddings and fixings on buildings. It sets out the problems involved in common cladding systems for buildings, and relates these problems to all the materials used: stone, masonry, concrete and glass-reinforced composites.
