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Brodmann's : Localisation in the Cerebral Cortex
It is one of the major "classics" of the neurological world. Even today it forms the basis for so-called "localisation" of function in the cerebral cortex. Brodmann's "areas" are still used to designate functional regions in the cortex, the part of the brain that brings the world that surrounds us into consciousness, and which governs our responses to the world. For example, we use "area 4" for the "motor" cortex, with which we control our muscles, "area 17" for "visual" cortex, with which we see, and so on. This nomenclature is used by neurologists and neurosurgeons in the human context, as well as by experimentalists in various animals. Indeed, Brodmann's famous "maps" of the cerebral cortex of humans, monkeys and other mammals must be among the most commonly reproduced figures in neurobiological publishing. The most famous of all is that of the human brain. There can be few textbooks of neurology, neurophysiology or neuroanatomy in which Brodmann is not cited, and his concepts pervade most research publications on systematic neurobiology.
Bridging laboratory and field research for genetic control of disease vectors
Contemporary research on genetic control of disease-transmitting insects knows two kinds of scientists: those that work in the laboratory and those known as ‘field people’. Over the last decade, both groups seem to have developed differing research priorities, address fundamentally different aspects within the overall discipline of infectious-disease control, and worse, have developed a scientific ‘language’ that is no longer understood by the ‘other’ party. This gap widens every day, between the North and the South, between ecologists and molecular biologists, geneticists and behaviourists, etc. The need to develop a common research agenda that bridges this gap has been identified as a top priority by all parties involved. Only then shall the goal of developing appropriate genetic-control strategies for vectors of disease become reality.
Breathing, feeding, and neuroprotection
New findings in brain research are being revealed on an almost daily basis, and the focus of this book is the fields of breathing, neuroprotection, and higher brain functions. An unresolved issue within respiration research and hence a topic of much interest is Where and how respiratory rhythm is generated in the brainstem, detailed analysis of which is presented herein. Chapters on neuroprotection examine the functional significance of the blood – brain barrier as an interface of blood and the central nervous system; other chapters look at health and disease in relation to the hypothalamic and limbic systems. In addition to animal experiments, research on the human brain is included, with a focus on the recently developed EEG/dipole tracing method. This book will be an invaluable reference for researchers in neuroscience and related fields.
Breast cancer chemosensitivity
In Breast Cancer Chemosensitivity, a group of world leading experts review critical aspects of resistance to systemic therapy in breast cancer patients. Beginning with a clinical overview of the problem Breast Cancer Chemosensitivity moves on to focus on the latest findings of molecular mechanisms of drug resistance. These include in-depth discussions on multidrug resistance by P-glycoprotein and the multidrug resistance protein family, resistance to therapeutic agent-induced apoptosis, cell cycle deregulation, deregulation of DNA repair, loss of tumor suppressor genes, integrin-mediated adhesion, insulin-like growth factors, epidermal growth factor, and ErbB2 in modulating breast cancer response to systemic therapy, especially, certain chemotherapeutic agents. Breast Cancer Chemosensitivity provides an example of using novel approaches for chemosensitization of breast cancer cells that gives readers an idea about the future direction in breast cancer treatment.
Branching Morphogenesis
Branching morphogenesis, the creation of branched structures in the body, is a key feature of animal and plant development. This book brings together, for the first time, expert researchers working on a variety of branching systems to present a state-of-the-art view of the mechanisms that control branching morphogenesis. Systems considered range from single cells, to blood vessel and drainage duct systems to entire body plans, and approaches range from observation through experiment to detailed biophysical modelling. The result is an integrated overview of branching.
Brain, Mind and Medicine : Essays in Eighteenth-Century Neuroscience
Ideas we associate with the 18th century are clearly seen in work published from the latter decades of the 17th century through the first decades of the 19th century. This is the "long 18th century", a period which exhibits multiple discourses in medicine, brain science and philosophy. The editors have deliberately adopted a "presentist" subtitle, "neuroscience", to emphasize that this collection of essays reflect a range of current thought about 18th century-studies of the nervous system in isolation and in context. There are six sections, each preceded by a short introduction.
Brain tumor pathology : Current diagnostic hotspots and pitfalls
Since Bailey and Cushing (1926), all brain tumor classifications have been called histogenetic. The nosographic position that the tumor types progressively acquired in the classification systems derived from the resemblance of tumor cells to those of the cytogenesis, modified whenever new information became available from different biological research fields and especially from molecular genetics. Classically, on the basis of the rough correspondence between the mature/immature aspect of tumor cells and the benign/malignant biological behavior of the tumors, the histological labels contained a prognostic significance. The supposed origin of the tumors was thus a factor for prognosis. Later on, with the concept of anaplasia (Cox, 1933; Kernohan et al., 1949) new criteria were introduced for establishing the malignancy grades of tumors. Immunohistochemistry and later molecular genetics further refined the prognostic diagnoses, substantially increasing the opportunities to recognize the cell origin of tumors, beside revealing the pathogenetic mechanisms. Prognoses became more accurate, as required by the greater and more targeted possibilities of therapy.
Brain Repair
Brain Repair, addresses all relevant issues underlying the mechanisms of brain damage, brain plasticity and post-traumatic reorganisation after CNS lesions. This book is divided the three major sections that follow; cellular and molecular basis of brain repair, plasticity and reorganisation of neural networks, and experimental therapy strategies. Brain Repair is written by high profile, international experts who describe in detail the newest results from basic research and highlight new model systems, techniques and therapy approaches. Based on a careful analysis of the cellular and molecular reaction patterns of the CNS to lesions, the contributions cover possibilities for endogenous reorganisation and repair as well as exciting new therapies emerging from basic research, some of which have already been introduced into the clinics.
Brain development in Drosophila melanogaster
The central nervous system (CNS) represents the organ with the highest structural and functional complexity. Accordingly, uncovering the mechanisms leading to cell diversity, patterning and connectivity in the CNS is one of the major challenges in developmental biology. The developing CNS of the fruitfly Drosophila melanogaster is an ideal model system to study these processes. Several principle questions regarding neurogenesis (like stem cell formation, cell fate specification, axonal pathfinding) have been addressed in Drosophila by focusing on the relatively simply structured truncal parts of the nervous system. This book provides an overview of some major facets of recent research on Drosophila brain development.
Brain Death : A Reappraisal
This text is intended to provide an overview of brain death. The topics explored in this book are the concept and historical approach of human death, clinical examinations of brain-dead patients, ancillary tests in coma and brain death, bioethical discussions of brain death and its relationship with some consciousness disturbances, and the legal considerations of human death.
Brain Control of Wakefulness and Sleep
The book is rich in references and leaves no aspect of the problem untouched. The morphological, pharmacological, physiological and mathematical modeling aspects of different components of the subject are treated to exhaustion...the book is richly illustrated and down-right comprehensive. It will delight those interested in the field, will inform those who need a context for their research efforts and is a must for graduate and medical libraries.
Botulinum toxin
Offering a step-by-step, practical approach to this commonly performed cosmetic procedure, Procedures in Cosmetic Dermatology: Botulinum Toxin, 5th Edition, enables you to master the up-to-date cosmetic techniques that produce the superior results your patients expect. It covers the science behind these neuromodulators and their usage areas in cosmetic dermatology, as well as the latest treatment options—all abundantly illustrated and evidence based. A substantial video library demonstrating injection techniques helps you successfully incorporate the latest procedures into your practice.
Botrytis : Biology, Pathology and Control
The book is the result of intensive work of 43 authors, all of them leading scientists in the Botrytis sciences. New technologies have arisen that when applied to long-standing problems or to test new hypotheses have been most rewarding and many of these are covered in this book.
Botany Illustrated : Introduction to Plants, Major Groups, Flowering Plant Families
This easy-to-use book helps you acquire a wealth of fascinating information about plants. There are 130 pages with text, each facing 130 pages of beautiful illustrations. Each page is a separate subject. Included is a coloring guide for the realistic illustrations. The illustration pages are composed of scientifically accurate line drawings with the true sizes of the plants indicated. Using colored pencils and the authors’ instructions, you can color the various plant structures to stand out in vivid clarity. Your knowledge of plants increases rapidly as you color the illustrations.
Botanical drug products : Recent developments and market trends
Botanicals, which have been part of human food and medicine for thousands of years, are perceived as being safer than synthetic pharmaceuticals. The global botanical drug market was expected to reach $26.6 billion by 2017. In terms of FDA regulations, botanical drugs are no different from non-botanical products, having to meet the safety and effectiveness standards of a new drug in accordance. This book comprises a complete start-to-end process from drug-idea conception, to drug development process.
Boreal Peatland Ecosystems
This volume adopts an ecosystems approach to understanding the world's boreal peatlands. It focuses on biogeochemical patterns and processes, production, decomposition, and peat accumulation, and provides additional information on animal and fungal diversity. A recurring theme is the legacy of boreal peatlands as impressive accumulators of carbon as peat over millennia. This carbon legacy is under threat from a wide diversity of disturbances, including wildfire, ongoing climate change, the changing chemistry of atmospheric deposition, and continuing resource exploitation. The volume is of inte.
Boreal Forest and Climate Change
There are several crucial feedbacks from forests to the climate system. The mechanisms for those feedbacks are elaborated in the book: they involve changes in the carbon cycle, albedo, N2O emissions and the production of aerosols. Much of this work is new and the feedback relationships have not yet been incorporated into models of the climate system. The book will be an important introduction for students and climate modellers alike, providing conceptual tools and ideas that are broadly applicable to terrestrial systems.
Bone Marrow Derived Progenitors
The ability of stem cells to acquire different desired phenotypes has opened the door for a new discipline: regenerative medicine. Much of the interest for this purpose is generated by embryonic stem cells, but their use is still controversial for moral reasons as well as scientifically. Less controversial and readily available are the adult bone marrow-derived progenitors including hematopoietic stem cells, endothelial progenitors and mesenchymal stem cells. The ambitious goal of this volume is to provide a comprehensive overview of the currently available information related to the therapeutic utility of adult bone marrow-derived cells. Each chapter has been written by an accomplished expert in the field, making this a hugely valuable resource for anyone looking for an up-to-the-minute assessment of current practice in adult bone marrow-derived cell therapy.
Biotic elicitors: Production, purification, and characterization
Details techniques to study biotic elicitors involved in the field of agriculture for the benefit of the environment and growers. Chapters guide readers through protein, carbohydrate, lipid, glycoprotein and glycolipid components derived from microorganisms and their production, purification, and characterization.
Biotechnology of medicinal plants with antiallergy properties : Research trends and prospects
Covers critically investigated information on medicinal plants prioritized for their anti-allergy properties. It offers insights into strategies related to the distribution, mechanism of action, and assessment of antiallergic medicinal plants, and also delves into crucial aspects of modern biotechnological tools, addressing their implementation challenges, presenting innovative approaches through case studies, and exploring opportunities for nanotechnologies. These elaborated discussions aim to raise awareness and bridge the gap between human health and the biodiversity of antiallergic medicinal plants.
