LINQ for Visual C# 2005
LINQ for Visual C# 2005 is a short, yet comprehensive guide to the major features of LINQ. It thoroughly covers LINQ to Objects, LINQ to SQL, LINQ to DataSet, and LINQ to XML. It also details significant enhancements to C#, .NET, and ADO.NET.
Lighting Design Basics, 3rd ed.
Offering fundamental concepts and prescriptive techniques in a highly visual format, this book provides clear, practical guidance on utilizing the latest in lighting techniques and technology to showcase a space without sacrificing utility. Covering more than 25 different design scenarios with in-depth rationale for proposed solutions, this book provides insightful distribution diagrams, floor plans, and details for lighting installation and construction. Real-world case studies illustrate lighting design in residential, commercial, healthcare, education, and hospitality settings, and skill-building exercises offer practice for real-world projects as well as NCIDQ and NCARB exam preparation.
Lessons Learned : Risk Management Issues in Genetic Counseling
The only book devoted exclusively to this specialty, Lessons Learned details the risk management issues involved in genetic counseling practice, and offers solid strategies for minimizing the risk of costly, career-damaging malpractice suits. Schmerler clearly identifies areas of practitioner liability and demonstrates how they may be averted, so counselors can better manage their practice while lowering the risk of legal action. Examples drawn from relevant court cases illustrate typical issues in malpractice, negligence, and breach of contract suits. With this in-depth knowledge, readers can refine their goals toward increased self-protection as well as client care.
Le dépistage du cancer du col de lutérus = Cervical cancer screening
Each year, cervical cancer kills approximately 1,000 people in France, making it the fifth leading cause of cancer death and the eighth most common cancer among women. While eradicating cervical cancer is not possible, a national screening campaign should significantly reduce its incidence. This campaign should be based, in particular, on the systematic use of Pap smears. Conventional Pap smears have already reduced the number of invasive cancers by more than 50%. Improving them requires optimizing their sensitivity. This book details the natural history of cervical cancer, its incidence and mortality, and the various aspects of screening: general principles, the French screening program, the different types of Pap smears, the role and contribution of the HPV test, the management of abnormal Pap smears, the role of colposcopy, and the follow-up of treated women. It is intended for all those involved in this screening : specialist interns and gynecologists, pathologists and biologists, public health physicians, but also general practitioners whose role in screening is privileged since they are at the forefront of medical demand.
Lattice : Multivariate Data Visualization with R
R is rapidly growing in popularity as the environment of choice for data analysis and graphics both in academia and industry. Lattice brings the proven design of Trellis graphics (originally developed for S by William S. Cleveland and colleagues at Bell Labs) to R, considerably expanding its capabilities in the process. Lattice is a powerful and elegant high level data visualization system that is sufficient for most everyday graphics needs, yet flexible enough to be easily extended to handle demands of cutting edge research. Written by the author of the lattice system, this book describes it in considerable depth, beginning with the essentials and systematically delving into specific low levels details as necessary. No prior experience with lattice is required to read the book, although basic familiarity with R is assumed.
KRAS : Methods and protocols
Details protocols ranging from high yield production metabolically labeled KRAS for NMR studies to approaches that quantify engagement of novel molecules that bind KRAS in live cells. Chapters focus on protein production and characterization, biochemical assays, cell-based assays, KRAS-membrane interactions, targeting KRAS, and cell models.
Key Clinical Trials in Erectile Dysfunction
Represents a critical appraisal of the major clinical trials that have had a significant impact on clinical research and practice during the last decade. Each trial follows a strict format, starting with reference to the original source of publication, details on the key investigators and their methods of research. The strengths and weaknesses of each trial are discussed as well as their influence on clinical practice. Articles are complemented by a diagrammatic summary of the trial design and the key findings.
Jubilee Line Extension : From concept to completion
Details the story of London Underground's award winning Jubilee Line Extension (JLE), how it came to being, how it was planned, how it was designed, built and commissioned, and how the millennium deadline imposed by the Dome was met. Always in the public eye and the political spotlight, the JLE has played a significant role in the success of the Canary Wharf development, improved public transport immeasurably in the areas of southeast and east London, and set new standards for London Underground and public transport.
Community Quality-of-Life Indicators : Best Cases VIII
Offers critical insights into the thriving international field of community indicators, incorporating the experiences of government leaders, philanthropic professionals, community planners and a wide range of academic disciplines. It illuminates the important role of community indicators in diverse settings and the rationale for the development and implementation of these innovative projects. details many of the practical “how to” aspects of the field as well as lessons learned from implementing indicators in practice. The case studies included here also demonstrate how, using a variety of data applications, leaders of today are monitoring and measuring progress and communities are empowered to make sustainable improvements in their wellbeing.
Clinical Blood Pool MR Imaging
MR Angiography covers the basic techniques, safety, efficacy, image processing and pharmaco-economic details to successfully implement a new level of MRA image quality with this new contrast agent.
Climate Variability, Predictability and Climate Risks : A European Perspective
This book provides an integrated assessment of issues related to climate variability and change, predictability and risks. It details both the technical aspects of variability and abrupt climate change and the agricultural and economical impacts and consequences.
Climate Change and Technological Options : Basic facts, Evaluation and Practical Solutions
climate change focussing on technical solutions for the most important and climate relevant economic sectors is presented. It is intended for key decision makers, and administrators within industry, agricultural and energy sectors, as well as masters students and post graduates. The first of three sections covers the scientific basis of climate change and the instruments to prevent or reduce negative climate effects. It includes a survey covering current practices at different levels.It discusses evaluation methods for climate impacts from industrial processes. Climate relevant processes and measures to reduce their impact such as sequestration are defined in the final section, with the main focus being on renewable resources. Details are given on climate impacts of waste prevention, recycling and waste management as well as are proposals for every day solutions.
Cities After Crisis : Reinventing Neighborhood Design from the Ground-Up
The book details how these crises have led to a new urban vision—from avantgarde modern design to an artisan aesthetic that calls for simplicity and the everyday, from the sustainable development paradigm to a resilient vision that defends de-growth and the re-wilding of cities, from a homogenizing globalism to a new localism that values what is distinctive and nearby, from the privatization of the public realm to the commoning and self-governance of urban resources, and from top-down to bottom-up processes based on the engagement and empowerment of communities.
Chromatin and Disease
It is more evident now than ever before that dynamic organization of human genome into nucleoprotein structure, chromatin confers the unique regulatory mechanisms for most of the cellular phenomena, which include replication, transcription, DNA repair, recombination and also apoptosis. The dynamic nature of the chromatin is regulated by chromatin modifications (epigenetic alterations), remodeling, histone chaperones and functional interactions of different chromatin interacting n- histone proteins. Dysfunction of this highly inter connected machineries disturb the cellular homoeostasis, and thereby causes several diseases. As we advance in our knowledge of chromatin function and also disease mechanisms in more details, their causal relationship is becoming more evident. This has lead to the identification of chromatin function as target for new generation therapeutics.
Chitosan-based nanocomposite materials : fabrication, characterization and biomedical applications
Discovery in the use of chitosan-based nanocomposites in biomedical applications, including the scope to which these novel materials have been incorporated by the community. It provides an exceptional insight into the strategies for the synthesis and chemical modifications of chitosan, characterization techniques, their use as anticancer agents, antimicrobial, antiviral, and antifungal agents, their role in the biomedical field, and applications in drug delivery, gene therapy, dentistry, orthopedics, etc. This book will also emphasize the challenges with previous signs of progress and way for further research, details relating to the current pioneering technology, and future perspectives with a multidisciplinary approach. Furthermore, it presents up-to-date information on the economics, toxicity, and regulations related to these novel materials.
Characteristics Finite Element Methods in Computational Fluid Dynamics
This book details a systematic characteristics-based finite element procedure to investigate incompressible, free-surface and compressible flows. The fluid dynamics equations are derived from basic thermo-mechanical principles and the multi-dimensional and infinite-directional upstream procedure is developed by combining a finite element discretization of a characteristics-bias system with an implicit Runge-Kutta time integration. For the computational solution of the Euler and Navier Stokes equations, the procedure relies on the mathematics and physics of multi-dimensional characteristics. As a result, the procedure crisply captures contact discontinuities, normal as well as oblique shocks, and generates essentially non-oscillatory solutions for incompressible, subsonic, transonic, supersonic, and hypersonic inviscid and viscous flows.
Chaos : A Program Collection for the PC
This new edition strives yet again to provide readers with a working knowledge of chaos theory and dynamical systems through parallel introductory explanations in the book and interaction with carefully-selected programs supplied on the accompanying diskette. The programs enable readers, especially advanced-undergraduate students in physics, engineering, and math, to tackle relevant physical systems quickly on their PCs, without distraction from algorithmic details. For the third edition of Chaos: A Program Collection for the PC, each of the previous twelve programs is polished and rewritten in C++ (both Windows and Linux versions are included). A new program treats kicked systems, an important class of two-dimensional problems, which is introduced in Chapter 13. Each chapter follows the structure: theoretical background; numerical techniques; interaction with the program; computer experiments; real experiments and empirical evidence; reference.
Care of Astronomical Telescopes and Accessories : A Manual for the Astronomical Observer and Amateur Telescope Maker
guide for anyone who wants to understand more than just the basics of astronomical telescopes and accessories, and how to maintain them in the peak of condition. The latest on safely adjusting, cleaning, and maintaining your equipment is combined with thoroughly updated methods from the old masters. Here, too, are details of choosing new and used optics and accessories, along with enhancements you can make to extend their versatility and useful lifetime. This book is for you. Really. Looking after an astronomical telescope isn’t only for the experts - although there are some things that only an expert should attempt - and every serious amateur astronomer will find invaluable information here, gleaned from Barlow Pepin's many years’ experience working with optical instruments.
Cancerimmunotherapies : Solid tumors and hematologic malignancies
Presents the clinical scope of cancer immunotherapeutic agents for solid tumors and Hematologic malignancies, elaborates on the scientific details of their modes of action, and presents the impact of these agents on oncology, patients and the broader healthcare system. At present, cancer immunotherapies fall broadly into three categories: immune checkpoint inhibitors (ICIs), adoptive T cell therapies, and cancer vaccines which have distinct mechanisms of action. Immune checkpoint inhibitors rely upon disrupting tumor antigen recognition as self by the immune system through inhibition of checkpoint molecules. Adoptive T cell therapies involve the engineering of T cells ex vivo to target and destroy tumor cells. The first part of this book will provide an overview of the discovery and mechanistic details of the technology. The second part will be devoted to elaborating on the clinical outcomes, successes and limitations for specific tumor subtypes, which includes both solid tumors and hematologic malignances for both pediatric and adult populations.
Cancer immunotherapy : Methods and protocols
Details multiple areas of new and emerging methods to develop the next generation of immunotherapy treatments. Chapters guide readers through analysis and characterisation of the interactions between tumour and immune cells, and cell engineering tools for cancer treatment, to provide a unique and compelling set of techniques instrumental to work with, and engineer, immune cells. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.



















