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Sensitization of Cancer Cells for Chemo/immuno/Radio-therapy
Sensitization of Cancer Cells for Chemo/Immuno/Radio-therapy, edited by Benjamin Bonavida, reviews novel approaches developed to reverse tumor cell resistance to chemo/immuno/radio-therapy and the use of various sensitizing agents in combination with various cytotoxics. Such sensitizing agents target gene products that regulate resistance and therefore identify novel targets for drug development. This book also introduces several of the current approaches that have been developed by established investigators in the field that are aimed at overcoming resistance. This book is the first that compiles studies on tumor cell sensitization and is useful for students, scientists, clinicians and pharmaceutical companies.
Semiparametric Theory and Missing Data
Combines much of what is known in regard to the theory of estimation for semiparametric models with missing data in an organized and comprehensive manner. It starts with the study of semiparametric methods when there are no missing data. The description of the theory of estimation for semiparametric models is at a level that is both rigorous and intuitive, relying on geometric ideas to reinforce the intuition and understanding of the theory. These methods are then applied to problems with missing, censored, and coarsened data with the goal of deriving estimators that are as robust and efficient as possible.
Semi-Markov Chains and Hidden Semi-Markov Models toward Applications : Their use in Reliability and DNA Analysis
This book is concerned with the estimation of discrete-time semi-Markov and hidden semi-Markov processes. Semi-Markov processes are much more general and better adapted to applications than the Markov ones because sojourn times in any state can be arbitrarily distributed, as opposed to the geometrically distributed sojourn time in the Markov case. Another unique feature of the book is the use of discrete time, especially useful in some specific applications where the time scale is intrinsically discrete. The models presented in the book are specifically adapted to reliability studies and DNA analysis.
Semantic Web Services : Concepts, Technologies, and Applications
Semantic Web services combine Web services communication technology with the intelligent processing of ontology-based metadata to achieve highly integrated enterprise application integration scenarios, for service look-up, schema matching, or protocol negotiation, for example. Rudi Studer and his team deliver a self-contained compendium about this exciting field, starting with the basic standards and technologies and also including advanced applications in eGovernment and eHealth. The contributions provide both the theoretical background and the practical knowledge necessary to understand the essential ideas and to design new cutting-edge applications.
Self-healing construction materials : Fundamentals, monitoring and large scale applications
Provides a thorough overview of all techniques for producing self-healing construction materials. Construction materials (cement-based, bituminous, metals, and alloys) are prone to cracking, which with the progress of time can lead to compromising of the structural integrity of critical infrastructure. Self-healing materials form a new class of materials that have inbuilt engineered properties to counteract damage and repair it before it becomes critical. The methods for monitoring, modeling, and assessing self-healing are also reviewed. The final section of the book discusses the future outlook and potential extension of self-healing concepts to other materials (e.g., heritage structures and soils).
Selenium : Its Molecular Biology and Role in Human Health
Selenium is an essential trace element in the diet of humans and many other life forms. As discussed in this book, selenium plays an important role in preventing certain forms of cancer, heart disease and other cardiovascular and muscle disorders. Evidence points to numerous other health benefits including an indispensable function in development, male reproduction and the immune system. In addition, selenium serves as an antiviral agent and may delay the onset of AIDS in HIV positive patients and delay the aging process. This element occurs primarily in cellular proteins in the form of a novel amino acid selenocysteine. The emphasis of this book is on the current status of the molecular biology of selenium. The importance of this element in human health is also highlighted.
Seismic retrofit of existing reinforced Concrete Buildings
Seismic Retrofit of Existing Reinforced Concrete Buildings readers will also find : Detailed treatment of each available strengthening technique, complete with advantages and disadvantages / In-depth guidelines to select a specific technique for a given building type and/or engineering scenario / Step-by-step guidance through the assessment/retrofitting process
Seeds for Diversity and Inclusion : Agroecology and Endogenous Development
This book will contribute to a more nuanced debate around seed system resilience that goes beyond the dominant dichotomous conceptualization of seed governance often characterized as traditional vs modern, subsistence vs commercial, or local vs global. While reflecting on the expanding oligopoly in the current seed system, the authors argue that such classifications limit our ability to critically reflect on and acknowledge the diverse approaches through which seed governance is practiced around the world, at various scales, creating a mosaic of dynamic complementarities and autonomies.
Security in pervasive computing ; Vol. 3450 ; 2nd International Conference, SPC 2005, Boppard, Germany, April 6-8, 2005, Proceedings
The objective of this second conference was to develop new security concepts for complex application scenarios based on systems like handhelds, phones, smartcards, RFID-chips and smart labels hand in hand with the emerging technology of ubiquitous and pervasive computing. In particular the conference focused on methods and technologies concerning the identification of risks, the definition of security policies, and the development of security and privacy measures, especially cryptographic protocols that are related to specific aspects of ubiquitous and pervasive computing like mobility, location-based services, adhoc networking, resource allocation / restriction, invisibility, and secure hardware / software platforms.
Scenarios : Models, transformations and tools ; International Workshop, Dagstuhl Castle, Germany, September 7-12, 2003, Revised Selected Papers
Visual notations and languages continue to play a pivotal role ˆ in the design of complex software systems. In many cases visual notations are used to - scribe usage or interaction scenarios of software systems or their components. While representing scenarios using a visual notation is not the only possibility, a vast majority of scenario description languages is visual. Scenarios are used in telecommunications as Message Sequence Charts, in object-oriented system design as Sequence Diagrams, in reverse engineering as execution traces, and in requirements engineering as, for example, Use Case Maps or Life Sequence Charts. These techniques are used to capture requirements, to capture use cases in system documentation, to specify test cases, or to visualize runs of existing systems. They are often employed to represent concurrent systems that int- act via message passing or method invocation.
Scale Space and Variational Methods in Computer Vision ; 1st International Conference, SSVM 2007, Ischia, Italy, May 30 - June 2, 2007, Proceedings
Constitutes the refereed proceedings of the First International Conference on Scale Space Methods and Variational Methods in Computer Vision, SSVM 2007. This book introduces topical sections on scale space and features extraction, image enhancement and reconstruction, image segmentation and visual grouping, motion analysis, and optical flow.
Saving dental implants
Comprehensive, multidisciplinary approach to all aspects of dental implant maintenance, based on treatment outcomes. The book offers a complete reference to all factors in long-term success in dental implants. and examines treatment outcomes, provides advice on how to manage implants for long-term success, and supports clinicians in avoiding and managing peri-implant complications.
SALICYLIC ACID - A Plant Hormone
This book provides information about a natural chemical, Salicylic Acid, that could be raised to the status of the above phytohormones because it has significant impact on various aspects of plant life.
Rotifera X: Rotifer Research : Trends, new tools and recent advances
This volume reflects the latest developments in the research of a global community of rotifer researchers, who came together at Illmitz, Austria in 2003. Contributions are manifold and span fields from phylogeny and evolution of the phylum Rotifera to practical aspects of aquaculture and ecotoxicology. Major issues include phylogeny and evolution, genetics and molecular ecology, new aspects of rotifer anatomy through the application of confocal laser-scanning microscopy, anhydrobiosis, long-term studies in lakes and rivers, population dynamics and community ecology, trophic relationships between copepods and rotifers, alongside biodiversity studies based on classical taxonomic concepts and molecular approaches. Although primarily focussed on one taxonomic group, the scientific outcome of this meeting is of relevance to the study of other aquatic microinvertebrates as well.
Root Physiology : From Gene to Function
The classical boundaries between physiology, biochemistry and molecular biology have vanished. There has been a strong focus on a limited number of model species, including Arabidopsis thaliana. That focus has allowed greater insight into the significance of specific genes for plant development and functioning. However, many species are very different from A. thaliana, in that they are mycorrhizal, develop a symbiosis with N2-fixing microsymbionts, or have other specialised root structures. Also, some have a much greater capacity to resist extreme environments, such as soil acidity, salinity, flooding or heavy-metal toxicities, due to specific adaptations. Research on species other than A. thaliana is therefore pivotal, to develop new knowledge in plant sciences in a comprehensive manner. This fundamental new knowledge can be the basis for important applications in, e.g., agriculture and plant conservation. Although significant progress has been made, much remains to be learnt. It is envisaged that discoveries made in the recent past will likely lead to major breakthroughs in the next decade.
Robotic Exploration and Landmark Determination : Hardware-Efficient Algorithms and FPGA Implementations
This book presents hardware-efficient algorithms and FPGA implementations for two robotic tasks, namely exploration and landmark determination. The work identifies scenarios for mobile robotics where parallel processing and selective shutdown offered by FPGAs are invaluable. The book proceeds to systematically develop memory-driven VLSI architectures for both the tasks. The architectures are ported to a low-cost FPGA with a fairly small number of system gates. A robot fabricated with this FPGA on-board serves to validate the efficacy of the approach. Numerous experiments with the robot are reported.
RNA nanostructures : Design, characterization, and applications
Details protocols for computer-assisted design and experimental characterization of RNA nanostructures. Chapters guide readers through RNA nanotechnology, design and characterization of RNA nanostructures, assessment of immunology of nanomaterials, biosensing and drug delivery, various biomedical applications, and delivery approaches for therapeutic RNA nanoparticles.
Rightshore! : Successfully SAP(R) Projects Offshore
At a time when business demands urge companies to innovate and CIOs face increasing cost pressures, offshore delivery offers the opportunity to industrialize the implementation processes for system harmonization, consolidation, and enhancement, thereby realizing substantial cost savings and quality improvements. Rightshore® - a registered trademark of Capgemini - is about organizing the distributed delivery process that embraces on-site, nearshore and offshore services.
Reviews in Fluorescence 2006
Reviews in Fluorescence offers an essential reference material for any lab working in the fluorescence field. All academics, bench scientists, and industry professionals wishing to take advantage of the latest and greatest in the continuously emerging field of fluorescence will find it an invaluable resource.
Reviews in Fluorescence 2005
It summarizes the year’s progress in fluorescence, with authoritative analytical reviews specialized enough to be attractive to professional researchers, yet also appealing to the wider audience of scientists in related disciplines of fluorescence. Reviews in Fluorescence 2005 topics include: - RNA folding and RNA-protein binding analyzed using fluorescence. / Progress in Lanthanides as luminescent probes. / The combined use of fluorescence spectroscopy and X-Ray crystallography to elucidating structure and dynamics of proteins. / Tapered fibers for cell studies. / Fluorescence-based ophthalmic glucose monitoring for diabetics. / High-throughput tissue image cytometry. / DNA condensation using FCS. / Multidimensional TCSPC.
