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Ribosome biogenesis : Methods and protocols
This volume provides comprehensive reviews and describes the latest techniques to study eukaryotic ribosome biogenesis. For more than 50 years ribosomes are a major research topic. Our knowledge about ribosome biogenesis and function such as transcription, mRNA modification, and translation was the sine qua non for developing the powerful RNA-based vaccines against RNA-viruses causing the world-threatening Covid-19 pandemia. The chapters in this book are organized into six parts. Part One discusses a comparative survey about the unity and diversity of ribosome biogenesis in pro- and eukaryotic cells. Part Two deals with the genomic organization of eukaryotic rDNA and the role of RNA polymerase I in ribosomal RNA transcription. Part Three explores in vitro methods to study RNA polymerase I structure and its function, and Part Four analyzes the nucleo-cytoplasmic transport of assembled ribosomes and RNP complexes. Part Five covers modifications that increase the complexity of rRNAs, and Part Six provides readers with a review of eukaryotic translation and - for the first time - describes a new method to analyze translation in vitro.
Revolution and evolution in private law
The essays range across all areas of private law, including contract, tort, unjust enrichment and property. No area has been immune from development. That fact itself is unsurprising, but an extended examination of the particular circumstances and contexts which delivered some of private law’s most important developments has its own special significance for what it might indicate about the shape, and the shaping, of private law regimes in the future.
Retrial Queueing Systems : A Computational Approach
Retrial Queueing Systems: A Computational Approach also : Presents motivating examples in telephone and computer networks. / Establishes a comparative analysis of the retrial queues versus standard queues with waiting lines and queues with losses. / Integrates a wide range of techniques applied to the main M/G/1 and M/M/c retrial queues, and variants with general retrial times, finite population and the discrete-time case. / Surveys basic results of the matrix-analytic formalism and emphasizes the related tools employed in retrial queues. / Discusses a few selected retrial queues with QBD, GI/M/1 and M/G/1 structures.
Rethinking Nordic Courts
This book examines whether a distinctly Nordic procedural or court culture exists and what the hallmarks of that culture are. Do Nordic courts and court proceedings share a distinct set of ideas and values that in combination constitute the core of a regional legal culture? How do Europeanisation, privatisation, diversification and digitisation influence courts and court proceedings in the Nordic countries? The book traces the genesis and formation of Nordic courts and justice systems to provide a richer comprehension of contemporary Nordic legal culture, and an understanding of the relationship between legal cultural stability and change. In answering these questions, the book provides models for conceptualising procedural culture.
Research, ethics and risk in the authoritarian field
This Open Access book offers a synthetic reflection on the authors’ fieldwork experiences in seven countries within the framework of ‘Authoritarianism in a Global Age’, a major comparative research project. It responds to the demand for increased attention to methodological rigor and transparency in qualitative research, and seeks to advance and practically support field research in authoritarian contexts. Without reducing the conundrums of authoritarian field research to a simple how-to guide, the book systematically reflects and reports on the authors’ combined experiences in (i) getting access to the field, (ii) assessing risk, (iii) navigating ‘red lines’, (iv) building relations with local collaborators and respondents, (v) handling the psychological pressures on field researchers, and (vi) balancing transparency and prudence in publishing research. It offers unique insights into this particularly challenging area of field research, makes explicit how the authors handled methodological challenges and ethical dilemmas, and offers recommendations where appropriate.
Report on Global Environmental Competitiveness
This book explores the environmental competitiveness of 133 countries around the world, presenting an index evaluation system to facilitate a comparative analysis of environmental competitiveness on a global scale. This is a new way to measure competitiveness in the light of the contradiction between world economic development and environmental protection. Global environmental competitiveness covers five aspects: the ecological environment, resources environment, environmental management, environmental impacts and environmental coordination. The authors use longitudinal study and horizontal analysis, combining qualitative and quantitative analysis methods so as to conduct an in-depth study of theoretical, empirical and methodological issues of global environmental competitiveness.
Religious offences in common law Asia : Colonial legacies, constitutional rights and contemporary practice
Providing rigorous studies of common law jurisdictions that have adopted similar provisions in their penal code, the contributors provide an original examination and analysis of the use and development of these religious clauses in their respective jurisdictions. They draw upon their insights into the background sociopolitical and constitutional contexts to consider how the inter-relationship of religion and state may determine the rationale and scope of religious offences.
Religious Education in Public Schools : Study of Comparative Law
This publication is a compilation of studies on religious instruction in state schools. It describes the diversity between states and analyzes the legislative basis of religious instruction in various countries. Whereas in some countries, religious instruction in state schools is optional or compulsory with the possibility to opt out, in other countries religious instruction is banned from state schools.The comparative analyses in this book will be of great value to researchers in educational research and to educational policymakers.
Religion in the public sphere : A comparative analysis of German, Israeli, American and International Law
How closely correlated should church and state be? May a state recognize or dignify the role and meaning of religion at all, and if so can it treat different religious groups differently? This book intends to answer these questions through a portrayal and comparison of various legal orders including those of Germany, Israel, France and the USA.
Reliability and validity of international large-scale assessment : Understanding IEA’s comparative studies of student achievement
This book describes and reviews the development of the quality control mechanisms and methodologies associated with IEA’s extensive program of educational research. A group of renowned international researchers, directly involved in the design and execution of IEA’s international large-scale assessments (ILSAs), describe the operational and quality control procedures that are employed to address the challenges associated with providing high-quality, comparable data.
Regulatory Genomics ; RECOMB 2004 International Workshop, RRG 2004, San Diego, CA, USA, March 26-27, 2004, Revised Selected Papers
Research in the field of gene regulation is evolving rapidly in an ever-changing scientific environment. Microarray techniques and comparative genomics have enabled more comprehensive studies of regulatory genomics and are proving to be powerful tools of discovery. The application of chromatin immunoprecipitation and microarrays (chIP-on-chip) to directly study the genomic binding locations of transcription factors has enabled more comprehensive modeling of regulatory networks. In addition, complete genome sequences and the comparison of numerous related species has demonstrated that conservation in non-coding DNA sequences often provides evidence for cis-regulatory binding sites. That said, much is still to be learned about the regulatory networks of these sequenced genomes.
Regularized system identification: learning dynamic models from data
Provides a comprehensive treatment of recent developments in kernel-based identification that are of interest to anyone engaged in learning dynamic systems from data. The reader is led step by step into understanding of a novel paradigm that leverages the power of machine learning without losing sight of the system-theoretical principles of black-box identification. The authors’ reformulation of the identification problem in the light of regularization theory not only offers new insight on classical questions, but paves the way to new and powerful algorithms for a variety of linear and nonlinear problems. Regression methods such as regularization networks and support vector machines are the basis of techniques that extend the function-estimation problem to the estimation of dynamic models. Many examples, also from real-world applications, illustrate the comparative advantages of the new nonparametric approach with respect to classic parametric prediction error methods.
Reframing the Alhambra: Architecture, Poetry, Textiles and Court Ceremonial
Resolves that impasse by investigating the neglected, interdisciplinary contexts of medieval poetics and optics and through comparative study of Islamic court ceremonials. This reframing enables the reconstruction of the underlying, integrated aesthetic, focusing on the harmonious interrelationship between diverse artistic media – architecture, poetry and textiles – in the experience of the beholder, resulting in a new understanding of the Alhambra.
Reforms, Organizational Change and Performance in Higher Education : A Comparative Account from the Nordic Countries
This book investigates the effects of changes in leadership and managerial structures of Nordic universities resulting from reforms in the last decade. It builds on a rich, comparative dataset across a multiplicity of system-wide (macro) and organisational (meso and micro) dimensions, namely: reform or policy initiatives; drivers, aims, instruments and actors; structural changes within universities; strategic and performance management ; the rise of accountability regimes; incentive and evaluative systems; and perceived changes/effects by the key actors involved, at various levels. The volume provides critical insights to the larger phenomenon of change and adaptation within the public sector. Its findings and implications are of relevance to social science researchers, policy makers, managers/administrators, and external stakeholders.
Refining nature : the landscape architecture of Peter Walker
Peter Walker is one of the most seminal and prolific figures in contemporary landscape design worldwide--both as a teacher and as practitioner. Among his best-known works are Nasher Garden in Dallas, Novartis Campus in Basel, Switzerland and the World Trade Center Memorial in New York. This academic review of Walker's unique oeuvre look closely at his design work and provides a comparative analysis
Reelin Glycoprotein : Structure, Biology and Roles in Health and Disease
Reelin glycoprotein is a major secretory protein with important roles in embryogenesis and during adult life. Reelin gene mutations or deficiency of the protein product cause abnormal cortical development and reelin signaling impairment in brain. Since the first discovery of the reelin mutant mouse in 1951 by Falconer, and later discovery of the gene for reelin in 1995, there has been an explosion of new knowledge about this important molecule. Reelin Glycoprotein: Structure, Biology and Roles in Health and Disease, written by an international panel of experts, summarizes the state of the knowledge on various aspects of reelin. Topics include the reelin gene and its receptors, downstream effector molecules in reelin signaling cascade, chemistry and structure of reelin, comparative anatomy of reelin, presence of reelin in various body tissues, reelin mutations, and abnormalities of reelin production in neuropsychiatric disorders and cancer. This book will serve as a foundation for analysis of this emerging novel protein for all neuroscientists and clinicians.
Re-Configurations : Contextualising Transformation Processes and Lasting Crises in the Middle East and North Africa
This book title and assembles both the historical consciousness and transformation of the MENA region in various disciplinary and topical facets. At the same time, it aims to go beyond the MENA region, contributing to critical debates on area studies while pointing out transregional and cultural references in a broad and comparative manner.
Reality Lost : Markets of Attention, Misinformation and Manipulation
This book looks at how a democracy can devolve into a post-factual state. The media is being flooded by populist narratives, fake news, conspiracy theories and make-believe. Misinformation is turning into a challenge for all of us, whether politicians, journalists, or citizens. In the age of information, attention is a prime asset and may be converted into money, power, and influence – sometimes at the cost of facts. The point is to obtain exposure on the air and in print media, and to generate traffic on social media platforms. With information in abundance and attention scarce, the competition is ever fiercer with truth all too often becoming the first victim. It is an analysis of the nuts and bolts of the information market, the attention economy and media eco-system which may pave way to postfactual democracy. Here misleading narratives become the basis for political opinion formation, debate, and legislation. To curb this development and the threat it poses to democratic deliberation, political self-determination and freedom, it is necessary that we first grasp the mechanisms and structural conditions that cause it.
Quality-of-Life Research in Chinese, Western and Global Contexts
The majority of studies on the quality of life have been conducted in Western contexts and are based on Western participants. Comparatively speaking, there are only a few studies that have been conducted in different Chinese contexts. Also, there are fewer QOL studies based on children and adolescents, or studies that examine the relationship between QOL and economic disadvantage. In addition, more research is needed to address the methodological issues related to the assessment of quality of life. It is the first book to cover research in Chinese, Western and global contexts in a single volume.
Quality Measures in Data Mining
This volume presents the state of the art concerning quality and interestingness measures for data mining. The book summarizes recent developments and presents original research on this topic. The chapters include surveys, comparative studies of existing measures, proposals of new measures, simulations, and case studies. Both theoretical and applied chapters are included. Papers for this book were selected and reviewed for correctness and completeness by an international review committee.
